Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Cited by (1,029)

Items 601–700 of 1,029

  1. TOR on the brain
    Michael G. Garelick, Brian Keith Kennedy · 2010 · Experimental Gerontology
  2. Sumoylation of amyloid precursor protein negatively regulates Aβ aggregate levels
    Yu-Qian Zhang, Kevin D. Sarge · 2008 · Biochemical and Biophysical Research Communications
  3. Brain-Derived Neurotrophic Factor Reduces Amyloidogenic Processing through Control of SORLA Gene Expression
    Michael Rohe, Michael Synowitz, Rainer Glaß, Steven M. Paul, Anders Nykjær, Thomas E. Willnow · 2009 · Journal of Neuroscience
  4. New clues to Alzheimer's disease: Unraveling the roles of amyloid and tau
    Bruce A. Yanker · 1996 · Nature Medicine
  5. Transgenic mice expressing Alzheimer amyloid precursor proteins
    Karen Hsiao · 1998 · Experimental Gerontology
  6. Mechanisms of Neurotoxicity Associated with Amyloid β Deposition and the Role of Free Radicals in the Pathogenesis of Alzheimer's Disease: A Critical Appraisal
    Lawrence M. Sayre, Michael G. Zagorski, Witold K. Surewicz, Grant A. Krafft, George L. Perry · 1997 · Chemical Research in Toxicology
  7. Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau
    Rayaprolu, Sruti, Higginbotham, Lenora, Bagchi, Pritha, Watson, Caroline M., Zhang, Tian, Levey, Allan I., Rangaraju, Srikant, Seyfried, Nicholas T. · 2021 · Neuropsychopharmacology
  8. Leveraging preclinical models for the development of Alzheimer disease therapeutics
    Kimberly A. Scearce-Levie, Pascal E. Sanchez, Joseph W. Lewcock · 2020 · Nature Reviews Drug Discovery
  9. Calcium-mediated Transient Phosphorylation of Tau and Amyloid Precursor Protein Followed by Intraneuronal Amyloid-β Accumulation
    Nathalie Pierrot, Susana Ferrão Santos, Christine Feyt, Marina Morel, Jean‐Pierre Brion, Jean Noël Octave · 2006 · Journal of Biological Chemistry
  10. Expression of human β‐secretase in the mouse brain increases the steady‐state level of β‐amyloid
    Ursula Bodendorf, Simone Danner, Frauke Fischer, Muriel Stefani, Christine Sturchler, Karl‐Heinz Wiederhold, Matthias Staufenbiel, Paolo Paganetti · 2002 · Journal of Neurochemistry
  11. Phosphorylation of Tau at S422 is enhanced by Aβ in TauPS2APP triple transgenic mice
    Grueninger, Fiona, Bohrmann, Bernd, Czech, Christian, Ballard, Theresa Maria, Frey, Johann R., Weidensteiner, Claudia, von Kienlin, Markus, Ozmen, Laurence · 2010 · Neurobiology of Disease
  12. Genetics, Functions, and Clinical Impact of Presenilin-1 (PSEN1) Gene
    Jaya Bagaria, Eva Bagyinszky, Seong Soo A. An · 2022 · International Journal of Molecular Sciences
  13. Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann‐Pick C disease
    Dwight C. German, E. Matthew Quintero, Chang‐Lin Liang, Benton Ng, Surender Punia, Chonglun Xie, John M. Dietschy · 2001 · The Journal of Comparative Neurology
  14. Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy
    Mark P. Mattson · 2000 · Experimental Gerontology
  15. Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome
    Abdul Shukkur Ebrahim, Atsushi Shimohata, Takumi Akagi, Wenxin Yu, Mika Yamaguchi, Miyuki Murayama, Dehua Chui, Tamaki Takeuchi, Kenji Amano, Karthik Harve Subramhanya et al. · 2006 · Human Molecular Genetics
  16. Neurofibrillary Pathology in Transgenic Mice Overexpressing V717F β-Amyloid Precursor Protein
    Eliezer Masliah, Abbyann Sisk, Margaret E. Mallory, Dora Games · 2001 · Journal of Neuropathology & Experimental Neurology
  17. The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain
    Carlo, Anne-Sophie, Gustafsen, Camilla, Mastrobuoni, Guido, Nielsen, Morten S., Burgert, Tilman, Hartl, Daniela, Rohe, Michael, Nykjaer, Anders, Herz, Joachim, Heeren, Joerg et al. · 2013 · The Journal of Neuroscience
  18. Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics
    Sala Frigerio, Carlo, De Strooper, Bart · 2016 · Annual Review of Neuroscience
  19. Small-Animal PET Imaging of Amyloid-Beta Plaques with [11C]PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease
    André Manook, Behrooz H. Yousefi, Antje Willuweit, Stefan Platzer, Sybille Reder, Andreas Voß, Marc C. Huisman, Markus Settles, Frauke Neff, Joachim Velden et al. · 2012 · PLoS ONE
  20. Elevation of Cystatin C in Susceptible Neurons in Alzheimer's Disease
    Amy Deng, Michael C. Irizarry, Roger M. Nitsch, John H. Growdon, George William Rebeck · 2001 · American Journal Of Pathology
  21. Decreased Rhythmic GABAergic Septal Activity and Memory-Associated θ Oscillations after Hippocampal Amyloid-β Pathology in the Rat
    Vincent Villette, Frédérique Poindessous‐Jazat, Axelle Simon, Clément Léna, Elodie Roullot, Brice Bellessort, Jacques Epelbaum, P. Dutar, Aline Stéphan · 2010 · Journal of Neuroscience
  22. Mechanisms for nitric oxide-induced cell death: Involvement of apoptosis
    Pierluigi Nicotera, Emanuela Bonfoco, Bernhard Brüne · 1995 · Advances in Neuroimmunology
  23. Endoplasmic reticulum chaperones inhibit the production of amyloid-β peptides
    Tatsuya Hoshino, Tadashi Nakaya, Wataru Araki, Keitarou Suzuki, Toshiharu Suzuki, Tohru Mizushima · 2007 · Biochemical Journal
  24. Long-Term Accumulation of Amyloid-β in Axons Following Brain Trauma Without Persistent Upregulation of Amyloid Precursor Protein Genes
    Akira Iwata, Xiaohan Chen, Tracy K. McIntosh, Kevin D. Browne, Douglas H. Smith · 2002 · Journal of Neuropathology & Experimental Neurology
  25. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer’s disease
    Hartman, Richard E., Laurer, Helmut, Longhi, Luca, Bales, Kelly R., Paul, Steven M., McIntosh, Tracy K., Holtzman, David M. · 2002 · The Journal of Neuroscience
  26. Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus
    Chihiro Tohda, T Tamura, Shogo Matsuyama, Katsuko Komatsu · 2006 · British Journal of Pharmacology
  27. CNS SIRT3 Expression Is Altered by Reactive Oxygen Species and in Alzheimer’s Disease
    Heather J. M. Weir, Tracey K. Murray, Patrick G. Kehoe, Seth Love, Eric M. Verdin, Michael J. O’Neill, Jon D. Lane, Nina Balthasar · 2012 · PLoS ONE
  28. Cystatin C Protects Neuronal Cells from Amyloid-β-induced Toxicity
    Belén Tizón, Elena M. Ribé, Weiqian Mi, Carol M. Troy, Efrat Levy · 2010 · Journal of Alzheimer s Disease
  29. ?-sheet breaker peptide inhibitor of Alzheimer's amyloidogenesis with increased blood-brain barrier permeability and resistance to proteolytic degradation in plasma
    Joseph F. Poduslo, Geoffry L. Curran, Asok R. Kumar, Blas Frangione, Claudio A. Soto · 1999 · Journal of Neurobiology
  30. It all sticks together—the APP-related family of proteins and Alzheimer's disease
    Thomas A. Bayer, Roberto Cappai, Colin Louis Masters, Konrad T. Beyreuther, Gerd Multhaup · 1999 · Molecular Psychiatry
  31. Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: The role of the complement system
    Giulio Maria Pasinetti · 1996 · Neurobiology of Aging
  32. Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo
    Eliezer Masliah, Chris Westland, Edward M. Rockenstein, Carmela R. Abraham, Margaret E. Mallory, I Veinberg, Elizabeth Sheldon, Lennart Mucke · 1997 · Neuroscience
  33. LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer’s Disease
    Van Gool, Bart, Storck, Steffen E., Reekmans, Sara M., Lechat, Benoit, Gordts, Philip L. S. M., Pradier, Laurent, Pietrzik, Claus U., Roebroek, Anton J. M. · 2019 · Molecular Neurobiology
  34. Insights into Alzheimer disease pathogenesis from studies in transgenic animal models
    Schaeffer, Evelin L, Figueiró, Micheli, Gattaz, Wagner F · 2011 · Clinics
  35. Single Chain Variable Fragments against β-Amyloid (Aβ) Can Inhibit Aβ Aggregation and Prevent Aβ-Induced Neurotoxicity
    Ruitian Liu, Bin Yuan, Sharareh Emadi, Andleeb Zameer, Philip Schulz, Chad McAllister, Yuri L. Lyubchenko, Gaddam Narsa Goud, Michael R. Sierks · 2004 · Biochemistry
  36. Affinity-Based Inhibition of β-Amyloid Toxicity
    Christopher W. Cairo, Andrea Strzelec, Regina M. Murphy, Laura L. Kiessling · 2002 · Biochemistry
  37. Ergothioneine rescues PC12 cells from β-amyloid-induced apoptotic death
    Jang, Jung-Hee, Aruoma, Okezie I., Jen, Ling-Sun, Chung, Hae Young, Surh, Young-Joon · 2004 · Free Radical Biology and Medicine
  38. Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice.
    Frank M. LaFerla, C K Hall, Lien T. Ngo, Gregory D. Jay · 1996 · Journal of Clinical Investigation
  39. Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait‐linked phenotype.
    Tomoki Yamatsuji, Takashi Okamoto, S. Takeda, Yoshitake Murayama, Noritaka Tanaka, Ikuo Nishimoto · 1996 · The EMBO Journal
  40. BACE1 gene deletion: Impact on behavioral function in a model of Alzheimer’s disease
    Kobayashi, Dione, Zeller, Michelle, Cole, Tracy, Buttini, Manuel, McConlogue, Lisa, Sinha, Sukanto, Freedman, Stephen, Morris, Richard G.M., Chen, Karen S. · 2008 · Neurobiology of Aging
  41. Appearance of Sodium Dodecyl Sulfate-Stable Amyloid β-Protein (Aβ) Dimer in the Cortex During Aging
    Enya, Miho, Morishima-Kawashima, Maho, Yoshimura, Masahiro, Shinkai, Yasuhisa, Kusui, Kaoru, Khan, Karen, Games, Dora, Schenk, Dale, Sugihara, Shiro, Yamaguchi, Haruyasu et al. · 1999 · The American Journal of Pathology
  42. Alzheimer's in 3D culture: Challenges and perspectives
    D'Avanzo, Carla, Aronson, Jenna, Kim, Young Hye, Choi, Se Hoon, Tanzi, Rudolph E., Kim, Doo Yeon · 2015 · BioEssays
  43. A critical analysis of the ‘amyloid cascade hypothesis’
    A. Armstrong, Richard · 2014 · Folia Neuropathologica
  44. Cannabinoids and the Brain
    Attila Köfalvi · 2007 · Springer eBooks
  45. Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease
    Oliver Wirths, Thomas A. Bayer · 2010 · International Journal of Alzheimer s Disease
  46. Nucleolin and Heterogeneous Nuclear Ribonucleoprotein C Proteins Specifically Interact with the 3′-Untranslated Region of Amyloid Protein Precursor mRNA
    Syed Hassan Ejaz Zaidi, James S. Malter · 1995 · Journal of Biological Chemistry
  47. Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation
    Lu Lin, Biljana Georgievska, Anna Mattsson, Ole Isacson A · 1999 · Proceedings of the National Academy of Sciences
  48. Regulation of astrocyte glutamine synthetase in epilepsy
    Eid, Tore, Tu, Nathan, Lee, Tih-Shih W., Lai, James C.K. · 2013 · Neurochemistry International
  49. Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease
    Watts, Joel C., Giles, Kurt, Grillo, Sunny K., Lemus, Azucena, DeArmond, Stephen J., Prusiner, Stanley B. · 2011 · Proceedings of the National Academy of Sciences
  50. In vivo optical imaging and dynamic contrast methods for biomedical research
    Elizabeth M. C. Hillman, Cyrus Amoozegar, Tracy S. Wang, Addason F.H. McCaslin, Matthew B. Bouchard, James Robert Mansfield, Richard M. Levenson · 2011 · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
  51. Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease
    Jessica L. Hoffman, Sara Faccidomo, Michelle Kim, Seth M. Taylor, Abigail E. Agoglia, Ashley M. May, Evan N. Smith, L.C. Wong, Clyde W. Hodge · 2019 · International review of neurobiology
  52. Amyloid-β-Induced Action Potential Desynchronization and Degradation of Hippocampal Gamma Oscillations Is Prevented by Interference with Peptide Conformation Change and Aggregation
    Firoz Roshan Kurudenkandy, Misha Y. Zilberter, Henrik Biverstål, Jenny Presto, Dmytro Honcharenko, Roger Strömberg, Jan Johansson, Bengt G. Winblad, André Fisahn · 2014 · Journal of Neuroscience
  53. The Pathogenesis of Alzheimer′s Disease: A Reevaluation of the “Amyloid Cascade Hypothesis”
    Richard A. Armstrong · 2011 · International Journal of Alzheimer s Disease
  54. A Reductionist View of Alzheimer's Disease
    Peter T. Lansbury · 1996 · Accounts of Chemical Research
  55. Exploring the efficacy of natural products in alleviating Alzheimer’s disease
    Amit Singh, Prajakta Deshpande, Neha Gogia · 2019 · Neural Regeneration Research
  56. A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment
    Li Liu, Ian J. Orozco, Emmanuel Planel, Yi Wen, Alexis Bretteville, Pavan Krishnamurthy, Lili Wang, Mathieu Herman, Helen Y. Figueroa, Wai Haung Yu et al. · 2008 · Neurobiology of Disease
  57. Amyloid-β Deposition Is Associated with Decreased Hippocampal Glucose Metabolism and Spatial Memory Impairment in APP/PS1 Mice
    Marcin Sadowski, Joanna E. Pankiewicz, Henrieta Scholtzova, Yong Ji, David Quartermain, Catrin H. Jensen, Karen Duff, Ralph A. Nixon, Rand J. Gruen, Thomas Wısnıewskı · 2004 · Journal of Neuropathology & Experimental Neurology
  58. The role of complement in Alzheimer’s disease pathology
    Mark R. Emmerling, M. Desiree Watson, Charlotte A. Raby, Katharyn Spiegel · 2000 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  59. Functional γ-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and γ-secretase substrates
    Stéphanie Baulac, Matthew J. LaVoie, William Taylor Kimberly, Jennifer Mae Strahle, Michael S. Wolfe, Dennis J. Selkoe, Weiming Xia · 2003 · Neurobiology of Disease
  60. Genes, models and Alzheimer's disease
    Paul F. Chapman, Agnieszka M. Falinska, Simon G. Knevett, Mark F. Ramsay · 2001 · Trends in Genetics
  61. Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models
    Zhao, Lingzhi, Gottesdiener, Andrew J., Parmar, Mayur, Li, Mingjie, Kaminsky, Stephen M., Chiuchiolo, Maria J., Sondhi, Dolan, Sullivan, Patrick M., Holtzman, David M., Crystal, Ronald G. et al. · 2016 · Neurobiology of Aging
  62. Modeling human neurodegenerative diseases in transgenic systems
    Miguel A. Gama Sosa, Rita De Gasperi, Gregory A. Elder · 2011 · Human Genetics
  63. Familial Alzheimer’s Disease Mutations in Presenilin Generate Amyloidogenic Aβ Peptide Seeds
    Sarah Veugelen, Takashi Saito, Takaomi C. Saido, Lucía Chávez‐Gutiérrez, Bart De Strooper · 2016 · Neuron
  64. Neuronal Structure is Altered by Amyloid Plaques
    Tara L. Spires‐Jones, Bradley T. Hyman · 2004 · Reviews in the Neurosciences
  65. APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis
    Leslie A. Crews, Edward M. Rockenstein, Eliezer Masliah · 2009 · Brain Structure and Function
  66. Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior
    Mark P. Mattson, Wenzhen Duan, Sic L. Chan, A. Cheng, Norman J. Haughey, Devin S. Gary, Z GUO, Jaewon Lee, Katsutoshi Furukawa · 2002 · Neurobiology of Aging
  67. Treatment with Simvastatin in Patients with Alzheimer’s Disease Lowers Both α- and β-Cleaved Amyloid Precursor Protein
    Magnus J.C. Sjögren, K Gustafsson, Steinar Syversen, Annika Olsson, Åke Edman, Pia Davidsson, Anders Wallin, Kaj Blennow · 2003 · Dementia and Geriatric Cognitive Disorders
  68. Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models
    Nicholson, Rachel M., Kusne, Yael, Nowak, Lee A., LaFerla, Frank M., Reiman, Eric M., Valla, Jon · 2010 · Brain Research
  69. Sortilin-related Receptor with A-type Repeats (SORLA) Affects the Amyloid Precursor Protein-dependent Stimulation of ERK Signaling and Adult Neurogenesis
    Rohe, Michael, Carlo, Anne-Sophie, Breyhan, Henning, Sporbert, Anje, Militz, Daniel, Schmidt, Vanessa, Wozny, Christian, Harmeier, Anja, Erdmann, Bettina, Bales, Kelly R. et al. · 2008 · Journal of Biological Chemistry
  70. The unsolved relationship of brain aging and late-onset Alzheimer disease
    Andreas Kern, Christian Behl · 2009 · Biochimica et Biophysica Acta (BBA) - General Subjects
  71. A highly insoluble state of Aβ similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice
    Ola Philipson, Per Hammarström, K. Peter R. Nilsson, Erik Portelius, Tommie Olofsson, Martin Ingelsson, Bradley T. Hyman, Kaj Blennow, Lars Lannfelt, Hannu Kalimo et al. · 2008 · Neurobiology of Aging
  72. Anti-Amyloid-β Immunotherapy in Alzheimer's Disease: Relevance of Transgenic Mouse Studies to Clinical Trials
    Donna M. Wilcock, Carol A. Colton · 2008 · Journal of Alzheimer s Disease
  73. Maintained synaptophysin immunoreactivity in Tg2576 transgenic mice during aging: correlations with cognitive impairment
    King, David L., Arendash, Gary W. · 2002 · Brain Research
  74. Inflammatory Cascade in Alzheimer’s Disease Pathogenesis: A Review of Experimental Findings
    Jade de Oliveira, Ewa Kucharska, Michelle Lima Garcez, Matheus Scarpatto Rodrigues, João Quevedo, Inés Moreno‐González, Josiane Budni · 2021 · Cells
  75. Behavioral Disturbances without Amyloid Deposits in Mice Overexpressing Human Amyloid Precursor Protein with Flemish (A692G) or Dutch (E693Q) Mutation
    Samir Kumar‐Singh, Ilse Dewachter, Dieder Moechars, Ursula Lübke, Chris De Jonghe, C. Ceuterick, Frédéric Checler, Asha Naidu, Barbara Cordell, Patrick P Cras et al. · 2000 · Neurobiology of Disease
  76. The inhibitory effects of β-amyloid on glutamate and glucose uptakes by cultured astrocytes
    Aleksandra Parpura‐Gill, Donald C. Beitz, Etsuro Uemura · 1997 · Brain Research
  77. Staging of Alzheimer's Pathology in Triple Transgenic Mice: A Light and Electron Microscopic Analysis
    Oh, Kwang-Jin, Perez, Sylvia E., Lagalwar, Sarita, Vana, Laurel, Binder, Lester, Mufson, Elliott J. · 2010 · International Journal of Alzheimer's Disease
  78. The Tottori (D7N) and English (H6R) Familial Alzheimer Disease Mutations Accelerate Aβ Fibril Formation without Increasing Protofibril Formation
    Yukiko Hori, Tadafumi Hashimoto, Yosuke Wakutani, Katsuya Urakami, Kenji Nakashima, Margaret M. Condron, Satoshi Tsubuki, Takaomi C. Saido, David B. Teplow, Takeshi Iwatsubo · 2006 · Journal of Biological Chemistry
  79. Exercise as a pro-cognitive, pro-neurogenic and anti-inflammatory intervention in transgenic mouse models of Alzheimer’s disease
    Sinead M. Ryan, Aine Marie Kelly · 2016 · Ageing Research Reviews
  80. The Role of Adenosine in Alzheimers Disease
    Anisur Rahman · 2009 · Current Neuropharmacology
  81. SYMPOSIUM: Clearance of Aβ from the Brain in Alzheimer' Disease: The Role of the Immune System in Clearance of Aβ from the Brain
    Delphine Boche, James A. R. Nicoll · 2008 · Brain Pathology
  82. Cdk5: One of the links between senile plaques and neurofibrillary tangles?
    Ming-Sum Lee, Li‐Huei Tsai · 2003 · Journal of Alzheimer s Disease
  83. SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types
    Gaël Yvert · 2001 · Human Molecular Genetics
  84. Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span
    Markus von Kienlin, Basil Künnecke, Friedrich Metzger, Guido Steiner, John Grayson Richards, Laurence Ozmen, Helmut Jacobsen, Hansruedi Loetscher · 2004 · Neurobiology of Disease
  85. Hyperphosphorylated tau and paired helical filament-like structures in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes
    Mustafa Ayberk Kurt · 2003 · Neurobiology of Disease
  86. β-Amyloid(Phe(SO3H)24)25–35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation
    Tibor Harkany, Siobhain M. O’Mahony, John P. Kelly, Katalin Soós, I Törõ, Botond Penke, Paul G.M. Luiten, Csaba J. Nyakas, Károly Gulya, Brian E. Leonard · 1998 · Behavioural Brain Research
  87. Age related changes in brain metabolites observed by 1H MRS in APP/PS1 mice
    Johanna Öberg, Christian Spenger, Fuhua Wang, Anders David Ragnar Andersson, Eric Westman, Peter Skoglund, Dan Sunnemark, Ulf Norinder, Tomas Klason, Lars‐Olof Wahlund et al. · 2007 · Neurobiology of Aging
  88. Tau phosphorylation increases in symptomatic mice overexpressing A30P α-synuclein
    Mark A. Frasier, Mark Walzer, L. McCarthy, Debra J. Magnuson, J.M. Lee, Carola A. Haas, Philipp J. Kahle, Benjamin L. Wolozin · 2004 · Experimental Neurology
  89. Relative Increase in Alzheimer's Disease of Soluble Forms of Cerebral Aβ Amyloid Protein Precursor Containing the Kunitz Protease Inhibitory Domain
    Robert D. Moir, Toni Lynch, Ashley Ian Bush, Scott Whyte, Anna Henry, Stuart D Portbury, Gerd Multhaup, David Henry Small, Rudolph E. Tanzi, Konrad T. Beyreuther et al. · 1998 · Journal of Biological Chemistry
  90. DegenerationIn Vivoof Rat Hippocampal Neurons by Wild-Type Alzheimer Amyloid Precursor Protein Overexpressed by Adenovirus-Mediated Gene Transfer
    Isao Nishimura, Taichi Uetsuki, Sergio Ulhoa Dani, Yoshiyuki Ohsawa, Izumu Saito, Hitoshi Okamura, Yasuo Uchiyama, Kazuaki Yoshikawa · 1998 · Journal of Neuroscience
  91. Mechanisms of neuronal death in disease: defining the models and the players
    Elena M. Ribé, Esther Serrano‐Saiz, Nsikan Akpan, Carol M. Troy · 2008 · Biochemical Journal
  92. Possible Causes of Alzheimer's Disease: Amyloid Fragments, Free Radicals, and Calcium Homeostasis
    Christian Hölscher · 1998 · Neurobiology of Disease
  93. Probing the Initial Stage of Aggregation of the Aβ10-35-protein: Assessing the Propensity for Peptide Dimerization
    Bogdan Tarus, John E. Straub, Dave Thirumalai · 2004 · Journal of Molecular Biology
  94. Immunotherapy for Alzheimer's disease
    Richard C. Dodel, Harald Juergen Hampel, Yansheng Du · 2003 · The Lancet Neurology
  95. Antagonistic Effects of β-Site Amyloid Precursor Protein-cleaving Enzymes 1 and 2 on β-Amyloid Peptide Production in Cells
    Guriqbal S. Basi, Normand L. Frigon, Robin Barbour, Tam Doan, Grace Gordon, Lisa McConlogue, Sukanto Sinha, Michelle Zeller · 2003 · Journal of Biological Chemistry
  96. Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons
    Sven Furler, J.C. Paterna, Mirjam Weibel, Hansruedi Büeler · 2001 · Gene Therapy
  97. Nasal Aβ Treatment Induces Anti‐Aβ Antibody Production and Decreases Cerebral Amyloid Burden in PD‐APP Mice
    Cynthia Ann Lemere, Ruth Maron, E.T. SPOONER, Trelawney J. Grenfell, Chica Mori, Roanak V Desai, Wayne W. Hancock, Howard L. Weiner, Dennis J. Selkoe · 2000 · Annals of the New York Academy of Sciences
  98. In Vitro Growth of Alzheimer's Disease β-Amyloid Plaques Displays First-Order Kinetics †
    William P. Esler, Evelyn R. Stimson, Joseph R. Ghilardi, Harry V. Vinters, Jonathan P. Lee, Patrick W. Mantyh, John E. Maggio · 1996 · Biochemistry
  99. Transgenic mouse models of Alzheimer’s disease
    Janus, Christopher, Chishti, M.Azhar, Westaway, David · 2000 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  100. Animal models of dementia and cognitive dysfunction
    Neha Neha, Rupinder Kaur Sodhi, Amteshwar Singh Jaggi, Nirmal Singh · 2014 · Life Sciences