Fear conditioning induces associative long-term potentiation in the amygdala

Rogan, Michael T., Stäubli, Ursula V., LeDoux, Joseph E.·1997·Nature
DOI 10.1038/37601

Cited by (999)

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  1. The history of long‐term potentiation as a memory mechanism: Controversies, confirmation, and some lessons to remember
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  2. Neural cytoskeleton capabilities for learning and memory
    Avner Priel, Jack A. Tuszyński, Nancy J. Woolf · 2009 · Journal of Biological Physics
  3. Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala
    Ingie Hong, Beomjong Song, Sukwon Lee, Jihye Kim, Jeongyeon Kim, Sukwoo Choi · 2009 · European Journal of Neuroscience
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  5. A stable brain from unstable components: Emerging concepts and implications for neural computation
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  6. Memory and long-term potentiation (LTP) dissociated: Normal spatial memory despite CA1 LTP elimination with Kv1.4 antisense
    Noam Meiri, Miao‐Kun Sun, Zachary Segal, Daniel L. Alkon · 1998 · Proceedings of the National Academy of Sciences
  7. Blocking, Unblocking, and Overexpectation of Fear: A Role for Opioid Receptors in the Regulation of Pavlovian Association Formation.
    Gavan P. McNally, Michael Pigg, Gabrielle Weidemann · 2004 · Behavioral Neuroscience
  8. Mechanisms of fear learning and extinction: synaptic plasticity–fear memory connection
    Natalia V. Luchkina, Vadim Y. Bolshakov · 2018 · Psychopharmacology
  9. Capsaicin-Induced Changes in LTP in the Lateral Amygdala Are Mediated by TRPV1
    Carsten Alexander Zschenderlein, Christine Gebhardt, Oliver von Bohlen und Halbach, Christoph Kulisch, Doris Albrecht · 2011 · PLoS ONE
  10. Spatiotemporal asymmetry of associative synaptic plasticity in fear conditioning pathways.
    Ryong-moon Shin, E. Tsvetkov, V. Bolshakov · 2006 · Neuron
  11. Natural noxious stimulation can induce long-term increase of spinal nociceptive responses
    Lars Jørgen Rygh, Frode Svendsen, Kjell Hole, Arne Tjølsen · 1999 · Pain
  12. Basolateral amygdala lesions impair both cue- and cocaine-induced reinstatement in animals trained on a discriminative stimulus task
    Irene A. Yun, Howard L. Fields · 2003 · Neuroscience
  13. The extended amygdala and the dopamine system: another piece of the dopamine puzzle.
    J. Fudge, A. Emiliano · 2003 · The Journal of Neuropsychiatry and Clinical Neurosciences
  14. GABAergic interneurons: The orchestra or the conductor in fear learning and memory?
    Elizabeth K. Lucas, Roger L. Clem · 2017 · Brain Research Bulletin
  15. Sleep Deprivation Impairs Consolidation of Cued Fear Memory in Rats
    Tankesh Kumar, Sushil K. Jha · 2012 · PLoS ONE
  16. Social buffering suppresses fear-associated activation of the lateral amygdala in male rats: behavioral and neurophysiological evidence
    Felipe Fuzzo, Jumpei Matsumoto, Yasushi Kiyokawa, Yukari Takeuchi, Taketoshi Ono, Hisao Nishijo · 2015 · Frontiers in Neuroscience
  17. Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia.
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  18. Amount of fear extinction changes its underlying mechanisms
    Bobae An, Jihye Kim, Kyungjoon Park, Sukwon Lee, Sukwoon Song, Sukwoo Choi · 2017 · eLife
  19. Noradrenergic Regulation of Fear and Drug-Associated Memory Reconsolidation
    James M. Otis, Craig T. Werner, Devin T Mueller · 2014 · Neuropsychopharmacology
  20. Translational evidence for a role of endocannabinoids in the etiology and treatment of posttraumatic stress disorder
    Alexander Neumeister, Jordan Seidel, Benjamin Ragen, Robert H. Pietrzak · 2014 · Psychoneuroendocrinology
  21. Functional neuroanatomy of the basolateral amygdala: Neurons, neurotransmitters, and circuits
    Alexander Joseph McDonald · 2020 · Handbook of behavioral neuroscience
  22. L‐Type Voltage‐Gated Calcium Channels Are Involved in the in Vivo and in Vitro Expression of Fear Conditioning
    Patricia Shinnick‐Gallagher, MARGARET G. McKERNAN, Jiangang Xie, Fatiha Zinebi · 2003 · Annals of the New York Academy of Sciences
  23. Long-Term Depression of Excitatory Synaptic Transmission in the Rat Amygdala
    Su‐Jane Wang, Po-Wu Gean · 1999 · Journal of Neuroscience
  24. The actin cytoskeleton in memory formation
    Raphael Lamprecht · 2014 · Progress in Neurobiology
  25. Role of AMPA receptor trafficking in NMDA receptor‐dependent synaptic plasticity in the rat lateral amygdala
    Shu Yan Yu, Dong Wu, Lidong Liu, Yuan Ge, Yu Tian Wang · 2008 · Journal of Neurochemistry
  26. A pathophysiological paradigm for the therapy of psychiatric disease
    Michael Spedding, Thérèse M. Jay, Jorge Costa e Silva, Laurent Perret · 2005 · Nature Reviews Drug Discovery
  27. The genetic basis of cognition
    Jonathan Flint · 1999 · Brain
  28. Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's disease
    Shira Knafo, César Venero, Paula Merino‐Serrais, Isabel Fernaud-Espinosa, Juncal González‐Soriano, Isidró Ferrer, Gabriel Santpere, Javier DeFelipe · 2009 · The Journal of Pathology
  29. Higher-Order Sensory Cortex Drives Basolateral Amygdala Activity during the Recall of Remote, but Not Recently Learned Fearful Memories
    Marco Cambiaghi, Anna Grosso, Ekaterina Likhtik, Raffaele Mario Mazziotti, Giulia Concina, Annamaria Renna, Tiziana Sacco, Joshua A. Gordon, Benedetto Sacchetti · 2016 · Journal of Neuroscience
  30. Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder
    Varun Kilaru, Shruti V. Iyer, Lynn M. Almli, Jennifer Strafford Stevens, Adriana Lori, Tanja Jovanović, Timothy D. Ely, Bekh Bradley, Elisabeth B. Binder, Nastassja Koen et al. · 2016 · Translational Psychiatry
  31. Learning and Memory
    John H. Byrne, Kevin S. LaBar, Joseph E. LeDoux, Glenn E. Schafe, Richard F. Thompson · 2014 · Elsevier eBooks
  32. Role of amygdala oscillations in the consolidation of emotional memories
    Pelletier, Joe Guillaume, Paré, Denis · 2004 · Biological Psychiatry
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  35. Association of the androgen receptor gene (AR) with ADHD and conduct disorder
    David E. Comings, Cynthia Chen, Shijuan Wu, Donn R. Muhleman · 1999 · Neuroreport
  36. Distribution of PSA-NCAM expression in the amygdala of the adult rat
    Juan Nácher, Enrique Lanuza, Bruce S. McEwen · 2002 · Neuroscience
  37. GABAB receptor-mediated presynaptic inhibition of glutamatergic and GABAergic transmission in the basolateral amygdala
    Junko Yamada · 1999 · Neuropharmacology
  38. Phosphorylated cyclic AMP response element binding protein expression induced in the periaqueductal gray by predator stress: its relationship to the stress experience, behavior and limbic neural plasticity
    Robert E. Adamec, Jacqueline J. Blundell, Paul Burton · 2003 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
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    A. Beyeler, J. Dabrowska · 2020 · Handbook of Behavioral Neuroscience
  44. Fear learning and memory across adolescent development
    Siobhan S. Pattwell, Francis S. Lee, Betty Jo Casey · 2013 · Hormones and Behavior
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    Nishith K. Mahanty, Pankaj Sah · 1999 · European Journal of Neuroscience
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    Ryong-Moon Shin, Keith Tully, Yan Li, Jun-Hyeong Cho, Makoto Higuchi, Tetsuya Suhara, Vadim Y. Bolshakov · 2010 · Proceedings of the National Academy of Sciences
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    D. Yaniv, A. Desmedt, R. Jaffard, G. Richter-Levin · 2004 · Brain research. Brain research reviews
  50. Epigenetic Modifications in Alzheimer’s Neuropathology and Therapeutics
    Michelle Marie Esposito, Goldie Libby Sherr · 2019 · Frontiers in Neuroscience
  51. Deficient long-term memory and long-lasting long-term potentiation in mice with a targeted deletion of neurotrophin-4 gene
    Cui-Wei Xie, David M. Sayah, Qi-Sheng Chen, Weizheng Wei, Desmond Smith, Xin Liu · 2000 · Proceedings of the National Academy of Sciences
  52. NMDA Currents and Receptor Protein Are Downregulated in the Amygdala during Maintenance of Fear Memory
    Fatiha Zinebi, Jiangang Xie, Jie Liu, Rex T. Russell, Joel P. Gallagher, Margaret G. McKernan, Patricia Shinnick‐Gallagher · 2003 · Journal of Neuroscience
  53. Cognitive neuroscience
    Thomas David Albright, Eric R. Kandel, Michael I. Posner · 2000 · Current Opinion in Neurobiology
  54. TrkB Modulates Fear Learning and Amygdalar Synaptic Plasticity by Specific Docking Sites
    Gabriele Musumeci, Carla Sciarretta, Antonio Rodríguez Moreno, Mumna Al Banchaabouchi, José Vicente Negrete‐Díaz, Marco Costanzi, Valeria Berno, Alexei V. Egorov, Oliver von Bohlen und Halbach, Vincenzo Cestari et al. · 2009 · Journal of Neuroscience
  55. Functional connections and epileptic spread between hippocampus, entorhinal cortex and amygdala in a modified horizontal slice preparation of the rat brain
    Ron Stoop, Étienne Pralong · 2000 · European Journal of Neuroscience
  56. Role of NMDA receptors in the lateralized potentiation of amygdala afferent and efferent neural transmission produced by predator stress
    Robert E. Adamec, Jacqueline J. Blundell, Paul Burton · 2005 · Physiology & Behavior
  57. Protein synthesis and the mechanisms of lasting change in anxiety induced by severe stress
    Robert E. Adamec, Kirby J. Strasser, J BLUNDELL, P. Burton, D MCKAY · 2005 · Behavioural Brain Research
  58. Functional Imaging of Stimulus Convergence in Amygdalar Neurons during Pavlovian Fear Conditioning
    Barot, Sabiha K., Chung, Ain, Kim, Jeansok J., Bernstein, Ilene L. · 2009 · PLoS ONE
  59. A Naturally-Occurring Histone Acetyltransferase Inhibitor Derived from Garcinia indica Impairs Newly Acquired and Reactivated Fear Memories
    Stephanie A. Maddox, Casey S. Watts, Valérie Doyère, Glenn E. Schafe · 2013 · PLoS ONE
  60. GABAergic implications in anxiety and related disorders
    Indu Arora, Pankaj Mal, Poonam Arora, Anushka Paul, Manish Kumar · 2024 · Biochemical and Biophysical Research Communications
  61. Block of γ-Aminobutyric Acid-A Receptor Insertion in the Amygdala Impairs Extinction of Conditioned Fear
    Hui‐Ching Lin, Sheng-Chun Mao, Po‐Wu Gean · 2009 · Biological Psychiatry
  62. β-Adrenergic Receptors Regulate the Acquisition and Consolidation Phases of Aversive Memory Formation Through Distinct, Temporally Regulated Signaling Pathways
    Hillary C. Schiff, Joshua P. Johansen, Mian Hou, David E A Bush, Emily K Smith, JoAnna E Klein, Joseph E. LeDoux, Robert M. Sears · 2016 · Neuropsychopharmacology
  63. Input-Specific Long-Term Depression in the Lateral Amygdala Evoked by Theta Frequency Stimulation
    Thomas Heinbockel, Hans‐Christian Pape · 2000 · Journal of Neuroscience
  64. Dopamine Regulation of Amygdala Inhibitory Circuits for Expression of Learned Fear
    Oh-Bin Kwon, Joo Han Lee, Hyun Jin Kim, Seung‐Ho Lee, Sanghyeon Lee, Min-Jae Jeong, Su-Jeong Kim, Hee-Jung Jo, BumJin Ko, Sunghoe Chang et al. · 2015 · Neuron
  65. Ensemble coding in amygdala circuits for associative learning
    Jan Gründemann, Andreas Lüthi · 2015 · Current Opinion in Neurobiology
  66. Sensory-Specific Associations Stored in the Lateral Amygdala Allow for Selective Alteration of Fear Memories
    Lorenzo Díaz-Mataix, Jacek Dębiec, Joseph E. LeDoux, Valérie Doyère · 2011 · Journal of Neuroscience
  67. Induction of long-term potentiation of single wide dynamic range neurones in the dorsal horn is inhibited by descending pathways
    Johannes Gjerstad, Arne Tjølsen, Kjell Hole · 2001 · Pain
  68. Innate visual object recognition in vertebrates: some proposed pathways and mechanisms
    Terence V. Sewards, Mark A. Sewards · 2002 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
  69. Antisense DNA against calcineurin facilitates memory in contextual fear conditioning by lowering the threshold for hippocampal long-term potentiation induction
    S Ikegami, Kaoru Inokuchi · 2000 · Neuroscience
  70. Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice
    Tobias Müller, Doris Albrecht, Christine Gebhardt · 2009 · Learning & Memory
  71. Onset and offset of aversive events establish distinct memories requiring fear and reward networks
    Marta Andreatta, Markus Fendt, Andreas Mühlberger, Matthias J. Wieser, Stefan Imobersteg, Ayse Yarali, Bertram Gerber, Paul Pauli · 2012 · Learning & Memory
  72. Blockade of NMDA Receptors in the Amygdala Prevents Latent Inhibition of Fear-Conditioning
    Cornelia Schauz, Michael Koch · 2000 · Learning & Memory
  73. Phosphorylation of ERK/MAP kinase is required for long-term potentiation in anatomically restricted regions of the lateral amygdala in vivo
    Glenn E. Schafe, Michael W. Swank, Sarina M. Rodrigues, Jacek Dębiec, Valérie Doyère · 2008 · Learning & Memory
  74. Current understanding of fear learning and memory in humans and animal models and the value of a linguistic approach for analyzing fear learning and memory in humans
    Raber, Jacob, Arzy, Shahar, Bertolus, Julie Boulanger, Depue, Brendan, Haas, Haley E., Hofmann, Stefan G., Kangas, Maria, Kensinger, Elizabeth, Lowry, Christopher A., Marusak, Hilary A. et al. · 2019 · Neuroscience & Biobehavioral Reviews
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  76. Fundamentals of the septo-hippocampal system
    J.A. Gray, Neil McNaughton · 2003 · Oxford University Press eBooks
  77. Amygdala Circuits for Fear Memory: A Key Role for Dopamine Regulation
    Joo Han Lee, Seung Ho Lee, Joung‐Hun Kim · 2016 · The Neuroscientist
  78. The role of serotonin in impulsive and aggressive behaviors associated with epilepsy-like neuronal hyperexcitability in the amygdala
    N. Bradley Keele · 2005 · Epilepsy & Behavior
  79. Effect of amphetamine on extrastriatal D2 dopamine receptor binding in the primate brain: A PET study
    Yuan-Hwa Chou, Christer Halldin, Lars Farde · 2000 · Synapse
  80. Functional MRI of long-term potentiation: imaging network plasticity
    Efrén Álvarez-Salvado, Vicente Pallarés, Andrea Moreno, Santiago Canals · 2013 · Philosophical Transactions of the Royal Society B Biological Sciences
  81. Methods for developmental studies of fear conditioning circuitry
    Pine, Daniel S, Fyer, Abby, Grun, Joseph, Phelps, Elizabeth A, Szeszko, Philip R, Koda, Vivian, Li, Wei, Ardekani, Babak, Maguire, Eleanor A, Burgess, Neil et al. · 2001 · Biological Psychiatry
  82. Impaired long-term potentiation and enhanced neuronal excitability in the amygdala of CaV1.3 knockout mice
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  83. Learning and reconsolidation implicate different synaptic mechanisms
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  85. Glutamate Plasticity in the Drunken Amygdala
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  89. Synergistic Activation of Dopamine D1 and TrkB Receptors Mediate Gain Control of Synaptic Plasticity in the Basolateral Amygdala
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  90. Homeostatic systems, biocybernetics, and autonomic neuroscience
    David S. Goldstein, Irwin J. Kopin · 2017 · Autonomic Neuroscience
  91. Orchestration of synaptic plasticity through AKAP signaling complexes
    Andrea L. Bauman, April S. Goehring, John D. Scott · 2003 · Neuropharmacology
  92. Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology
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  93. The amygdala mediates the emotional modulation of threat-elicited skin conductance response.
    Kimberly H. Wood, Lawrence Ver Hoef, David C. Knight · 2014 · Emotion
  94. Single cell plasticity and population coding stability in auditory thalamus upon associative learning
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  95. Activation of Group II Metabotropic Glutamate Receptors Induces Long-Term Depression of Synaptic Transmission in the Rat Amygdala
    Hui‐Ching Lin, Su‐Jane Wang, Ming‐Zen Luo, Po‐Wu Gean · 2000 · Journal of Neuroscience
  96. Adaptations or pathologies? Long-term changes in brain and behavior after a single exposure to severe threat
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  97. Rewarding Morphine-Induced Synaptic Function of δ-Opioid Receptors on Central Glutamate Synapses
    Bihua Bie, Wei Jian Zhu, Zhizhong Z. Pan · 2009 · Journal of Pharmacology and Experimental Therapeutics
  98. d-Cycloserine as an augmentation strategy for cognitive behavioral therapy of anxiety disorders
    Hofmann, Stefan G, Wu, Jade Q, Boettcher, Hannah · 2013 · Biology of Mood & Anxiety Disorders
  99. Valence encoding in the amygdala influences motivated behavior
    Dana M. Smith, Mary M. Torregrossa · 2021 · Behavioural Brain Research
  100. Computational validity: using computation to translate behaviours across species
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