Role of amygdala oscillations in the consolidation of emotional memories
Abstract
Much evidence indicates that emotional arousal generally improves memory and that the amygdala is responsible for this effect. The available data suggest that stress hormones and neuromodulators released in emotionally arousing conditions alter the activity of basolateral amygdala (BLA) neurons in the hours after the learning episode. In turn, these changes would facilitate synaptic plasticity elsewhere in the brain; however, the biological mechanisms underlying the facilitation of memory consolidation by the BLA remain unknown. This article focuses on data suggesting that synchronized oscillatory BLA activity promotes synaptic plasticity by facilitating interactions between neocortical and temporal lobe areas involved in declarative memory.
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The amygdala appears to remain in phase 1 longer than the hippocampus, but eventually, the phase 2 (inhibitory) period develops, perhaps while the amygdala is involved in the consolidation of the emotional memory.
“The amygdala appears to remain in phase 1 longer than the hippocampus, but eventually, the phase 2 (inhibitory) period develops, perhaps while the amygdala is involved in the consolidation of the emotional memory (Izquierdo and Medina [347]; Pelletier and Paré [348]; McGaugh [88]).”
From The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007) · cites this paper as Pelletier and Paré [348]
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- Authors
- Pelletier, J. G., & Paré, D.
- Affiliations
- Rutgers, The State University of New Jersey (US)
- Corresponding author
- Paré, Denis
- ORCID
- Paré, Denis
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2004-03
- Volume
- 55
- Issue
- 6
- Pages
- 559-562
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2028598103
- Cited by
- 71
- References
- 23
- Citations by year
- 2024: 1 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 4 · 2015: 4 · 2014: 2 · 2013: 5 · 2012: 5
- FWCI
- 2.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01MH066856)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- amygdala, memory consolidation, emotional memory, emotional arousal, basolateral amygdala, neural oscillations, synaptic plasticity, stress hormones, neuromodulators, temporal lobe, declarative memory
- MeSH terms
- Adrenal Cortex Hormones, Amygdala, Animals, Arousal, Electroencephalography, Emotions, Memory, Neurotransmitter Agents
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