Caffeine alters plasma adenosine levels
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Repeated caffeine exposure in rodents indicates an adaptive response in the adenosinergic system characterised by an increase in cerebral adenosine concentrations.
“Although evidence is scarce in humans [62], repeated caffeine exposure in rodents indicates an adaptive response in the adenosinergic system characterised by an increase in cerebral adenosine concentrations [83] and an upregulation in cerebral adenosine receptors [58 e 61].”
From The effect of caffeine on subsequent sleep: A systematic review and meta-analysis (2023) · cites this paper as [83]
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Fredholm, B. B., Bättig, K., Holmén, J., Nehlig, A., & Zvartau, E. E. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01396-6 · Cited by 2,624 · see citing works
A receptor for green tea polyphenol EGCG
Tachibana, H., Koga, K., Fujimura, Y., & Yamada, K. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb743 · Cited by 682 · see citing works
Ciruela, F., Casadó, V., Rodrigues, R. J., Luján, R., Burgueño, J., Canals, M., Borycz, J., Rebola, N., Goldberg, S. R., Mallol, J., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3574-05.2006 · Cited by 591 · see citing works
Ribeiro, J. A., & Sebastião, A. M. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1379 · Cited by 584 · see citing works
Clark, I., & Landolt, H. P. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.01.006 · Cited by 499 · see citing works
Arendash, G. W., Schleif, W. S., Rezai-Zadeh, K. P., Jackson, E. K., Zacharia, L. C., Cracchiolo, J. R., Shippy, D. C., & Tan, J. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.07.021 · Cited by 459 · see citing works
An Update on the Mechanisms of the Psychostimulant Effects of Caffeine
Ferré, S. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05196.x · Cited by 440 · see citing works
Coffee, caffeine and blood pressure: a critical review
Nurminen, M.-L., Niittynen, L., Korpela, R., & Vapaatalo, H. (1999) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600899 · Cited by 351 · see citing works
The effect of caffeine on subsequent sleep: A systematic review and meta-analysis
Gardiner, C., Weakley, J., Burke, L. M., Roach, G. D., Sargent, C., Maniar, N., Townshend, A., & Halson, S. L. (2023) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2023.101764 · Cited by 315 · see citing works
“Although evidence is scarce in humans [62], repeated caffeine exposure in rodents indicates an adaptive response in the adeno-sinergic system characterised by an increase in cerebral adenosine concentrations [83] and an upregulation in cerebral adenosine receptors [58 e 61].”
BackgroundEffects of caffeine on the human circadian clock in vivo and in vitro
Burke, T. M., Markwald, R. R., McHill, A. W., Chinoy, E. D., Snider, J. A., Bessman, S. C., Jung, C. M., O’Neill, J. S., & Wright, K. P. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aac5125 · Cited by 283 · see citing works
Adenosine Receptors and the Central Nervous System
Sebastião, A. M., & Ribeiro, J. A. (2009) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-89615-9_16 · Cited by 271 · see citing works
Chemical sensing of neurotransmitters
Pradhan, T., Jung, H. S., Jang, J. H., Kim, T. W., Kang, C., & Kim, J. S. (2014) · Chemical Society Reviews · doi:10.1039/c3cs60477b · Cited by 254 · see citing works
Caffeine’s Vascular Mechanisms of Action
Echeverri, D., Montes, F. R., Cabrera, M., Galán, A., & Prieto, A. (2010) · International Journal of Vascular Medicine · doi:10.1155/2010/834060 · Cited by 233 · see citing works
Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders
Ferré, S. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4212-2 · Cited by 209 · see citing works
Adenosine, caffeine, and sleep–wake regulation: state of the science and perspectives
Reichert, C. F., Deboer, T., & Landolt, H. (2022) · Journal of Sleep Research · doi:10.1111/jsr.13597 · Cited by 183 · see citing works
“Animal studies suggest that plasma adenosine levels rise during daily intake (Conlay et al., 1997).”
BackgroundAdenosine A1-A2A receptor heteromers: New targets for caffeine in the brain
Ferre, S. (2008) · Frontiers in bioscience · doi:10.2741/2852 · Cited by 149 · see citing works
Dose and Time Effects of Caffeine Intake on Human Platelet Adenosine A2AReceptors
Varani, K., Portaluppi, F., Gessi, S., Merighi, S., Ongini, E., Belardinelli, L., & Borea, P. A. (2000) · Circulation · doi:10.1161/01.cir.102.3.285 · Cited by 117 · see citing works
Ecto-enzymes: physiology meets pathology
Goding, J. W. (2000) · Journal of Leukocyte Biology · doi:10.1002/jlb.67.3.285 · Cited by 116 · see citing works
Huang, W., Cane, M. C., Mukherjee, R., Szatmary, P., Zhang, X., Elliott, V., Ouyang, Y., Chvanov, M., Latawiec, D., Wen, L., et al. (2015) · Gut · doi:10.1136/gutjnl-2015-309363 · Cited by 108 · see citing works
Saura, C. A., Mallol, J., Canela, E. I., Lluís, C., & Franco, R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.28.17610 · Cited by 103 · see citing works
Atrial fibrillation: comorbidities, lifestyle, and patient factors
Shantsila, E., Choi, E., Lane, D. A., Joung, B., & Lip, G. Y. H. (2024) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2023.100784 · Cited by 104 · see citing works
Meyers, B. M., & CAFARELLI, E. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00937.2004 · Cited by 97 · see citing works
Finger sweat analysis enables short interval metabolic biomonitoring in humans
Brunmair, J., Gotsmy, M., Niederstaetter, L., Neuditschko, B., Bileck, A., Slany, A., Feuerstein, M. L., Langbauer, C., Janker, L., Zanghellini, J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-26245-4 · Cited by 96 · see citing works
Shapiro, R. E. (2008) · Current Pain and Headache Reports · doi:10.1007/s11916-008-0052-z · Cited by 96 · see citing works
The Cardiovascular Effects of Methylxanthines
Riksen, N. P., Smits, P., & Rongen, G. A. P. J. M. (2010) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-13443-2_16 · Cited by 89 · see citing works
Role of Endogenous Adenosine as a Modulator of Syncope Induced During Tilt Testing
Saadjian, A., Lévy, S., Franceschi, F., Zouher, I., Paganelli, F. F., & Guieu, R. (2002) · Circulation · doi:10.1161/01.cir.0000023924.66889.4c · Cited by 90 · see citing works
Caffeine and seizures: A systematic review and quantitative analysis.
Koert, R. R. V., Bauer, P., Schuitema, I., Sander, J. W., & Visser, G. (2018) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2017.11.003 · Cited by 79 · see citing works
Voskoboinik, A., Kalman, J. M., & Kistler, P. M. (2018) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2018.01.012 · Cited by 79 · see citing works
The Role of Adenosine Signaling in Headache: A Review
Fried, N. T., Elliott, M. B., & Oshinsky, M. L. (2017) · Brain Sciences · doi:10.3390/brainsci7030030 · Cited by 76 · see citing works
Wei, Y., Xu, J., Miao, S., Wei, K., Peng, L., Wang, Y., & Wei, X. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2048291 · Cited by 73 · see citing works
León, D., Albasanz, J. L., Ruiz, M. A., Fernández, M., & Martı́n, M. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01008.x · Cited by 71 · see citing works
Neuropathic pain: Mechanisms and therapeutic strategies
Petroianu, G. A., Aloum, L., & Adem, A. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1072629 · Cited by 71 · see citing works
Antoniou, K., Papadopoulou‐Daifoti, Z., Hyphantis, T. N., Papathanasiou, G., Bekris, E., Μαρσέλος, Μ., Panlilio, L. V., Müller, C. E., Goldberg, S. R., & Ferré, S. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0173-6 · Cited by 69 · see citing works
Regulation of cerebrospinal fluid production by caffeine consumption
Han, M., Kim, H., Lee, Y.-S., Kim, D., Choi, J.-T., Pan, C.-S., Yoon, S., Baek, S., Kim, B.-S., Kim, J.-B., et al. (2009) · BMC Neuroscience · doi:10.1186/1471-2202-10-110 · Cited by 68 · see citing works
Porta, M. S., Vioqué, J., Ayude, D., Alguacil, J., Jariod, M., Ruíz, L., & Murillo, J. A. (2003) · European Journal of Epidemiology · doi:10.1023/a:1023700216945 · Cited by 57 · see citing works
Opposite actions of caffeine and creatine on muscle relaxation time in humans
Hespel, P., ‘t Eijnde, B. O., & Van Leemputte, M. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00255.2001 · Cited by 78 · see citing works
Environmental factors and disturbances of brain development
Gressèns, P., Mesplès, B., Sahir, N., Marret, S., & Sola, A. (2001) · Seminars in Neonatology · doi:10.1053/siny.2001.0048 · Cited by 54 · see citing works
Acute caffeine intake increases muscle oxygen saturation during a maximal incremental exercise test
Ruíz‐Moreno, C., Lara, B., de Souza, D. B., Gutiérrez‐Hellín, J., Romero‐Moraleda, B., Cuéllar-Rayo, Á., & Coso, J. D. (2019) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.14189 · Cited by 53 · see citing works
The impact of daily caffeine intake on nighttime sleep in young adult men
Weibel, J., Lin, Y.-S., Landolt, H.-P., Kistler, J., Rehm, S., Rentsch, K. M., Slawik, H., Borgwardt, S., Cajochen, C., & Reichert, C. F. (2021) · Scientific Reports · doi:10.1038/s41598-021-84088-x · Cited by 52 · see citing works
The Impact of Coffee and Caffeine on Multiple Sclerosis Compared to Other Neurodegenerative Diseases
Herden, L., & Weissert, R. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00133 · Cited by 43 · see citing works
Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial
Gardiner, C., Weakley, J. J. S., Burke, L. M., Fernandez, F., Johnston, R. D., Leota, J., Russell, S., Munteanu, G., TOWNSHEND, A. D., & Halson, S. L. (2024) · SLEEP · doi:10.1093/sleep/zsae230 · Cited by 46 · see citing works
Yang, J., Björklund, O., Lindström-Törnqvist, K., Lindgren, E., Eriksson, T. M., Kahlström, J., Chen, J., Schwarzschild, M. A., Tobler, I., & Fredholm, B. B. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90971.2008 · Cited by 37 · see citing works
Peripheral adenosine levels in euthymic patients with bipolar disorder
Gubert, C., Moritz, C. E. J., Vasconcelos-Moreno, M. P., Tietbohl-Santos, B., Sartori, J., Fijtman, A., Kauer‐Sant’Anna, M., Kapczinski, F. P., Battastini, A. M. O., & Magalhães, P. V. D. S. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.10.007 · Cited by 36 · see citing works
Modulation of neuroimmunity by adenosine and its receptors: Metabolism to mental illness
Chiu, G. S., & Freund, G. G. (2014) · Metabolism · doi:10.1016/j.metabol.2014.09.003 · Cited by 34 · see citing works
Caffeine-dependent changes of sleep-wake regulation: Evidence for adaptation after repeated intake
Weibel, J., Lin, Y.-S., Landolt, H., Garbazza, C., Kolodyazhniy, V., Kistler, J., Rehm, S., Rentsch, K., Borgwardt, S., Cajochen, C., et al. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109851 · Cited by 33 · see citing works
Recent advances in the role of the adenosinergic system in coronary artery disease
Paganelli, F. F., Gaudry, M., Ruf, J., & Guieu, R. (2020) · Cardiovascular Research · doi:10.1093/cvr/cvaa275 · Cited by 33 · see citing works
León, D., Albasanz, J. L., Ruiz, M. A., & Martı́n, M. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.11.028 · Cited by 33 · see citing works
Caffeine intake induces an alteration in human neutrophil A2A adenosine receptors
Varani, K., Portaluppi, F., Gessi, S., Merighi, S., Vincenzi, F., Cattabriga, E., Dalpiaz, A., Bortolotti, F., Belardinelli, L., & Borea, P. A. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5312-z · Cited by 33 · see citing works
Effects of chronic caffeine consumption on sleep and the sleep electroencephalogram in mice
Panagiotou, M., Meijer, M., Meijer, J. H., & Deboer, T. (2018) · Journal of Psychopharmacology · doi:10.1177/0269881118806300 · Cited by 31 · see citing works
Carrega, L., Saadjian, A., Mercier, L., Zouher, I., Bergé‐Lefranc, J., Gérolami, V., Giaime, P., Sbragia, P., Paganelli, F. F., Fenouillet, E., et al. (2007) · Heart Rhythm · doi:10.1016/j.hrthm.2007.03.002 · Cited by 32 · see citing works
Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation
Wong, C. X. J., Cheung, C. C., Montenegro, G., Oo, H. H., Peña, I. J., Tang, J. J., Tu, S. J., Wall, G. C., Dewland, T. A., Moss, J. D., et al. (2025) · JAMA · doi:10.1001/jama.2025.21056 · Cited by 31 · see citing works
Lopes, C. R., Oliveira, A., Gaspar, I. L., Rodrigues, M. S., Santos, J., Szabó, E. C., Silva, H. B. L., Tomé, Â. R., Canas, P. M., Agostinho, P. M., et al. (2023) · Biomolecules · doi:10.3390/biom13010106 · Cited by 29 · see citing works
Kerbaul, F., Collart, F., Giorgi, R., Zouher, I., Guillen, J., Gil, J., Saadjian, A., Mouly-Bandini, A., Habib, G., Gouin, F., et al. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000201005.34203.50 · Cited by 29 · see citing works
Procopio, M. C., Lauro, R., Nasso, C., Carerj, S., Squadrito, F., Bitto, A., Bella, G. D., Micari, A., Irrera, N., & Costa, F. (2021) · Biomedicines · doi:10.3390/biomedicines9020204 · Cited by 28 · see citing works
Montoya, G. A., Bakuradze, T., Eirich, M., Erk, T., Baum, M., Habermeyer, M., Eisenbrand, G., & Richling, E. (2014) · British Journal Of Nutrition · doi:10.1017/s0007114514002232 · Cited by 28 · see citing works
Coffee, pancreatic cancer, and K-rasmutations: updating the research agenda
Porta, M. S., Malats, N., Alguacil, J., RUIZ, L., Jariod, M., Carrato, A., RIFÁ, J., & Guarner, L. (2000) · Journal of Epidemiology & Community Health · doi:10.1136/jech.54.9.656 · Cited by 28 · see citing works
A selective adenosine sensor derived from a triplex DNA aptamer
Patel, M. R., Dutta, A., & Huang, H. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-011-4996-1 · Cited by 26 · see citing works
Time for abstention from caffeine before an adenosine myocardial perfusion scan
MAJD-ARDEKANI, J., CLOWES, P., MENASH-BONSU, V., & NUNAN, T. O. (2000) · Nuclear Medicine Communications · doi:10.1097/00006231-200004000-00011 · Cited by 27 · see citing works
The Use of Caffeine by People with Epilepsy: the Myths and the Evidence
Bauer, P. R., & Sander, J. W. A. S. (2019) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-019-0948-5 · Cited by 25 · see citing works
Understanding Quantitative Circadian Regulations Are Crucial Towards Advancing Chronotherapy
Chowdhury, D., Wang, C., Lü, A., & Zhu, H. (2019) · Cells · doi:10.3390/cells8080883 · Cited by 24 · see citing works
Qian, J., Zhang, Y., Qu, Y., Zhang, L., Shi, J., Zhang, X., Liu, S., Kim, B. H., Hwang, S. J., Zhou, T., et al. (2018) · Biology of Reproduction · doi:10.1093/biolre/ioy155 · Cited by 25 · see citing works
Time to Recover From Daily Caffeine Intake
Lin, Y.-S., Weibel, J., Landolt, H., Santini, F., Garbazza, C., Kistler, J., Rehm, S., Rentsch, K., Borgwardt, S., Cajochen, C., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2021.787225 · Cited by 24 · see citing works
Lin, Y.-S., Weibel, J., Landolt, H., Santini, F., Slawik, H. C., Borgwardt, S., Cajochen, C., & Reichert, C. (2023) · Scientific Reports · doi:10.1038/s41598-022-26808-5 · Cited by 31 · see citing works
Caffeine ingestion and antigen‐stimulated human lymphocyte activation after prolonged cycling
Fletcher, D. K., & BISHOP, N. C. (2010) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2010.01223.x · Cited by 23 · see citing works
Iglesias, I., León, D., Ruiz, M. A., Albasanz, J. L., & Martı́n, M. (2006) · Amino Acids · doi:10.1007/s00726-005-0293-7 · Cited by 20 · see citing works
Modulatory effects of caffeine on oxidative stress and anxiety-like behavior in ovariectomized rats
Caravan, I., Sevastre-Berghian, A., Moldovan, R., Decea, N., Orăsan, R., & Filip, G. A. (2016) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2015-0502 · Cited by 20 · see citing works
Fletcher, D. K., & BISHOP, N. C. (2011) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.21.2.155 · Cited by 20 · see citing works
Evaluating the Validity of Caffeine Use Disorder
Budney, A. J., Lee, D. C., & Juliano, L. M. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-015-0611-z · Cited by 20 · see citing works
Caffeine Modulates Spontaneous Adenosine and Oxygen Changes during Ischemia and Reperfusion
Wang, Y., & Venton, B. J. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00251 · Cited by 19 · see citing works
Down‐regulation of rat brain adenosine A1receptors at the end of pregnancy
León, D., Albasanz, J. L., Fernández, M., Ruiz, M. A., & Martı́n, M. (2004) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02220.x · Cited by 19 · see citing works
Simões-Henriques, C. F., Mateus‐Pinheiro, M., Gaspar, R., Pinheiro, H., Duarte, J. M., Baptista, F. I., Canas, P. M., Ribeiro, C., Cunha, R. A., Ambrósio, A. F., et al. (2019) · European Journal of Neuroscience · doi:10.1111/ejn.14561 · Cited by 18 · see citing works
Xanthine Derivatives in the Heart: Blessed or Cursed?
Szentmiklosi, A. J., Cseppentö, A., Gesztelyi, R., Zsuga, J., Körtvély, Á., Harmati, G., & Nánási, P. P. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711796642391 · Cited by 18 · see citing works
A simple one-step assay platform based on fluorescence quenching of macroporous silicon
Yoo, L., Ahn, K.-Y., Ahn, J., Laurell, T., Lee, Y. M., Yoo, P. J., & Lee, J. (2012) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2012.09.012 · Cited by 17 · see citing works
Craving espresso: the dialetics in classifying caffeine as an abuse drug
dos Santos, M. K. F., Gavioli, E. C., Rosa, L. S., Soares-Rachetti, V. D. P., & Soares, B. L. (2018) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-018-1570-9 · Cited by 17 · see citing works
Lagier, D., Née, L., Guieu, R., Kerbaul, F., Fenouillet, E., Roux, N., Giorgi, R., Théron, A., Grisoli, D., Gariboldi, V., et al. (2018) · European Journal of Anaesthesiology · doi:10.1097/eja.0000000000000824 · Cited by 16 · see citing works
Caffeine exposure alters adenosine system and neurochemical markers during retinal development
Brito, R., Pereira‐Figueiredo, D., Socodato, R., Paes‐de‐Carvalho, R., & Calaza, K. D. C. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13683 · Cited by 16 · see citing works
Coffee, Atrial Fibrillation, and Circulating Ceramides in Patients with Chronic Heart Failure
Signori, C., Meessen, J. M. T. A., Laaksonen, R., Maggioni, A. P., Novelli, D., Blanda, A., Jylhä, A., Nicolis, E., Targher, G., Tavazzi, L., et al. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c03741 · Cited by 14 · see citing works
Astley, C., Souza, D., & Polito, M. (2018) · International Journal of Exercise Science · doi:10.70252/kqvq5193 · Cited by 14 · see citing works
Guieu, R., Degioanni, C., Fromonot, J., Maria, L. C. D., Ruf, J., Deharo, J., & Brignole, M. (2022) · Biomedicines · doi:10.3390/biomedicines10051127 · Cited by 13 · see citing works
Guieu, R., Brignole, M., Deharo, J., Deharo, P., Mottola, G., Groppelli, A., Paganelli, F. F., & Ruf, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147584 · Cited by 13 · see citing works
Hoexter, M. Q., Rosa, P. S., Tufik, S. B., & Mello, L. E. (2005) · Epilepsia · doi:10.1111/j.1528-1167.2005.63904.x · Cited by 13 · see citing works
Biagi, G., Giorgi, I., Livi, O., Pacchini, F., Rum, P., Scartoni, V., Costa, B., Mazzoni, M. R., & Giusti, L. (2002) · Il Farmaco · doi:10.1016/s0014-827x(02)01200-4 · Cited by 13 · see citing works
Valenti, O., Zambon, A., & Boehm, S. (2021) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyab049 · Cited by 10 · see citing works
Yu, Y., Yang, X., Hu, G., Tong, K., Yin, Y., & Yu, R. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1290731 · Cited by 11 · see citing works
Caffeine reduces the sensitivity of vasodilator MPI for the detection of myocardial ischaemia: Pro
Reyes, E. (2016) · Journal of Nuclear Cardiology · doi:10.1007/s12350-015-0371-5 · Cited by 11 · see citing works
A case–control study of drinking beverages and the risk of multiple sclerosis in Iran
Dastoorpoor, M., Nabavi, S. M., Majdinasab, N., Javid, A. Z., Angali, K. A., & Seyedtabib, M. (2023) · Journal of Health Population and Nutrition · doi:10.1186/s41043-023-00364-8 · Cited by 11 · see citing works
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Bourgeois‐Vionnet, J., Ryvlin, P., Elsensohn, M., Michel, V., Valton, L., Derambure, P., Frazzini, V., Hirsch, É., Maillard, L. G., Bartoloméi, F., et al. (2021) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2021.108486 · Cited by 10 · see citing works
Modulating P1 Adenosine Receptors in Disease Progression of SOD1G93A Mutant Mice
Armida, M., Matteucci, A., Pèzzola, A., Baqi, Y., Müller, C. E., Popoli, P., & Potenza, R. L. (2019) · Neurochemical Research · doi:10.1007/s11064-019-02745-0 · Cited by 10 · see citing works
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Yalcin, N., Chen, S., Yu, E. S., Liu, T.-T., Yen, J., Atalay, Y. B., Qin, T., Celik, F., van den Maagdenberg, A. M. J. M., Moskowitz, M. A., et al. (2018) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x18768955 · Cited by 9 · see citing works
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Reich, N., Mannino, M., & Kotler, S. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105577 · Cited by 8 · see citing works
Iglesias, I., Albasanz, J. L., & Martı́n, M. (2014) · Journal of Caffeine Research · doi:10.1089/jcr.2014.0010 · Cited by 8 · see citing works
Olajuyigbe, O. O., Adeoye-Isijola, M. O., Okon, V., Adedayo, O., & Coopoosamy, R. M. (2017) · Acta Biochimica Polonica · doi:10.18388/abp.2016_1327 · Cited by 8 · see citing works
Caffeine Consumption and Heart Rate and Blood Pressure Response to Regadenoson
Bitar, A., Mastouri, R. A., & Kreutz, R. P. (2015) · PLoS ONE · doi:10.1371/journal.pone.0130487 · Cited by 8 · see citing works
Adenosine Concentration in Patients With Neurally Mediated Syncope
Groppelli, A., Brignole, M., Chefrour, M., Gastaldi, M., Oufir, F. E., Deharo, J., Parati, G., & Guieu, R. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.900023 · Cited by 7 · see citing works
Akboğa, M. K., İnanç, İ. H., Keskin, M., Şabanoğlu, C., & Görenek, B. (2021) · Cardiology in Review · doi:10.1097/crd.0000000000000426 · Cited by 6 · see citing works
Santoso, L. F. A. S., Nasr, K., Roumani, A. M., Zeid, H. K. A., & Dabbous, M. S. (2024) · Health Science Reports · doi:10.1002/hsr2.70105 · Cited by 5 · see citing works
Montes, F. R., Cabrera, M., Delgadillo, A., Salgar, C., & Echeverri, D. (2008) · Vascular Pharmacology · doi:10.1016/j.vph.2008.11.002 · Cited by 5 · see citing works
Daly, J. W. (1998) · Springer eBooks · doi:10.1007/978-1-4757-2913-9_5 · Cited by 5 · see citing works
Porous Silicon Biosensors Employing Emerging Capture Probes
Urmann, K., Tenenbaum, E., Walter, J., & Segal, E. (2015) · Springer series in materials science · doi:10.1007/978-3-319-20346-1_4 · Cited by 5 · see citing works
(2003) · Chemie in unserer Zeit · doi:10.1002/ciuz.200390058 · Cited by 5 · see citing works
- Authors
- Conlay, L. A., Conant, J. A., deBros, F., & Wurtman, R.
- Affiliations
- Harvard University (US)
- Massachusetts Institute of Technology (US)
- Venue
- Nature
- Published
- 1997-09-11
- Volume
- 389
- Issue
- 6647
- Pages
- 136-136
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1631317414
- Cited by
- 133
- References
- 0
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 8 · 2023: 6 · 2022: 5 · 2021: 9 · 2020: 2 · 2019: 7 · 2018: 12 · 2017: 3 · 2016: 7 · 2015: 6 · 2014: 4 · 2013: 1 · 2012: 3
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Adenosine and Purinergic Signaling
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Molecular Research
- Keywords
- caffeine, plasma adenosine, methylxanthines, adenosine receptors, adenosine receptor blockade, caffeine withdrawal, dose-response relationship
- MeSH terms
- Adenosine, Animals, Caffeine, Humans, Injections, Intravenous, Male, Sympathomimetics, Tyramine, Rats, Sprague-Dawley, Receptors, Purinergic P1, Rats
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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