Cited by 174Neural dynamics and brain functionNeuroscience and Music PerceptionHearing, Cochlea, Tinnitus, Genetics

Thalamic modulation of high-frequency oscillating potentials in auditory cortex

Barth, Daniel S., MacDonald, Kurt D.·1996·Nature

Abstract

Perhaps the most widely recognized but least understood electrophysiological activity of the cerebral cortex is its characteristic electrical oscillations. Recently, there have been efforts to understand the mechanisms underlying high-frequency gamma oscillations(approximately 40 Hz) because they may coordinate sensory processing between populations of cortical cells. High-resolution cortical recordings show the gamma oscillations are constrained to sensory cortex, that they occur independently in auditory and somatosensory cortex, and that they are phase-locked between primary and secondary sensory cortex. As yet, the mechanism of their neurogenesis is unknown. Whereas cortical neurons can produce gamma oscillations without subcortical input, they may also be modulated by the thalamus and basal forebrain. Here we report that the neural generator of gamma oscillations in auditory cortex seems to be intracortical, serving to synchronize interactions between the primary and secondary areas. The acoustic thalamus directly modulates these oscillations, which are inhibited by stimulation of the dorsal and ventral divisions of the medial geniculate nucleus (MGd and MGv) and evoked by stimulation of the adjacent posterior intralaminar nucleus (PIL).

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Crossref · 10.1038/383078a0

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  • Stimulation of the posterior intralaminar nucleus modulates synchronous gamma oscillations in the auditory cortex.

    “it has been shown that stimulation of the posterior intralaminar nucleus modulates synchronous gamma oscillations in the auditory cortex [62].”

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Authors
Barth, D. S., & MacDonald, K. D.
Affiliations
University of Colorado Boulder (US)
Venue
Nature
Published
1996-09
Volume
383
Issue
6595
Pages
78-81
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W2046154593
Cited by
174
References
25
Citations by year
2026: 1 · 2024: 4 · 2022: 2 · 2021: 4 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 6 · 2016: 1 · 2015: 5 · 2014: 3 · 2013: 3 · 2012: 7
FWCI
8.02
Type
journal article
Language
en
Open access
closed
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
  • Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
Keywords
gamma oscillations, auditory cortex, medial geniculate body, cortical synchronization, sensory processing
MeSH terms
Animals, Auditory Cortex, Electrophysiology, Geniculate Bodies, Neural Inhibition, Thalamic Nuclei, Thalamus, Rats

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