Alzheimer's disease
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Each is checked against this paper’s own text: does it say what the citing paper says it does?
Efforts to rationally design AD therapeutics based on compounds that control Aβ aggregation have been hampered by the lack of a complete understanding of the neurotoxic role of various Aβ aggregates.
“In this regard, efforts to rationally design AD therapeutics based on compounds that control Aβ aggregation have been hampered by the lack of a complete understanding of the neurotoxic role of various Aβ aggregates.22”
From Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ<sub>42</sub>Peptide (2012) · cites this paper as [22]
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Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
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Self-citationAmbadipudi, S., Biernat, J., Riedel, D., Mandelkow, E., & Zweckstetter, M. (2017) · Nature Communications · doi:10.1038/s41467-017-00480-0 · Cited by 782 · see citing works
The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy
Sengupta, U., Nilson, A. N., & Kayed, R. (2016) · EBioMedicine · doi:10.1016/j.ebiom.2016.03.035 · Cited by 740 · see citing works
Alzheimer's Disease: Treatment Strategies and Their Limitations.
Passeri, E., Elkhoury, K., Morsink, M., Broersen, K., Linder, M., Tamayol, A., Malaplate, C., Yen, F. T., & Arab-Tehrany, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232213954 · Cited by 592 · see citing works
Dominguez, L. J., Veronese, N., Vernuccio, L., Catanese, G., Inzerillo, F., Salemi, G., & Barbagallo, M. (2021) · Nutrients · doi:10.3390/nu13114080 · Cited by 433 · see citing works
Lifespan brain activity, β-amyloid, and Alzheimer's disease
Jagust, W. J., & Mormino, E. C. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.09.004 · Cited by 221 · see citing works
Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ<sub>42</sub>Peptide
Sharma, A. K., Pavlova, S. T., Kim, J., Finkelstein, D., Hawco, N. J., Rath, N. P., Kim, J., & Mirica, L. M. (2012) · Journal of the American Chemical Society · doi:10.1021/ja210588m · Cited by 202 · see citing works
Sun, Y., Zhang, H., Zhang, X., Wang, W., Chen, Y., Cai, Z., Wang, Q., Wang, J., & Shi, Y. (2023) · Redox Biology · doi:10.1016/j.redox.2023.102690 · Cited by 151 · see citing works
Type 2 diabetes mellitus, dyslipidemia, and Alzheimer’s disease
Carlsson, C. M. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100012 · Cited by 109 · see citing works
Contribution of proteases to the hallmarks of aging and to age-related neurodegeneration
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Huang, H., Zheng, S., Yang, Z., Wu, Y., Li, Y., Qiu, J., Cheng, Y., Lin, P., Lin, Y., Guan, J., et al. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhac099 · Cited by 57 · see citing works
HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective
Chu, Q., Diedrich, J. K., Vaughan, J. M., Donaldson, C. J., Nunn, M. F., Lee, K.-F., & Saghatelian, A. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b03463 · Cited by 46 · see citing works
Gomaa, A. A., Makboul, R. M., El-Mokhtar, M. A., Abdel-Rahman, E. A., Ahmed, I. A., & Nicola, M. A. (2019) · Cytokine · doi:10.1016/j.cyto.2018.10.017 · Cited by 45 · see citing works
The Role of Genetic, Environmental, and Dietary Factors in Alzheimer’s Disease: A Narrative Review
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In vivo diffusion tensor imaging of amyloid‐β‐induced white matter damage in mice
Sun, S.-W., Liang, H.-F., Mei, J., Xu, D., & Shi, W.-X. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-130236 · Cited by 27 · see citing works
Li, X., Li, T., Zhan, F., Cheng, F., Lu, L., Zhang, B., Li, J., Hu, Z., Zhou, S., Jia, Y., et al. (2022) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00520 · Cited by 18 · see citing works
Wang, X.-B., Cui, N.-H., Yang, J., Qiu, X.-P., Gao, J.-J., Yang, N., & Zheng, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111406 · Cited by 15 · see citing works
Bae, J., Logan, P. E., Acri, D. J., Bharthur, A., Nho, K., Saykin, A. J., Risacher, S. L., Nudelman, K., Polsinelli, A. J., Pentchev, V., et al. (2023) · Alzheimer's & Dementia · doi:10.1002/alz.13319 · Cited by 14 · see citing works
- Authors
- Mucke, L.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Mucke, Lennart
- ORCID
- Mucke, Lennart
- Venue
- Nature
- Published
- 2009-10
- Volume
- 461
- Issue
- 7266
- Pages
- 895-897
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2066918975
- Cited by
- 456
- References
- 0
- Citations by year
- 2026: 12 · 2025: 30 · 2024: 34 · 2023: 43 · 2022: 62 · 2021: 44 · 2020: 20 · 2019: 21 · 2018: 19 · 2017: 19 · 2016: 27 · 2015: 22 · 2014: 14 · 2013: 22 · 2012: 27
- FWCI
- 14.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Pharmacology › Cholinesterase and Neurodegenerative Diseases
- Keywords
- Alzheimer's disease, neurodegeneration, population aging, drug development, drug evaluation, disease mechanisms
- MeSH terms
- Aging, Alzheimer Disease, Animals, Genetic Testing, Humans, United States, Amyloid beta-Peptides, Treatment Failure, Age of Onset, Controlled Clinical Trials as Topic, Stem Cell Transplantation, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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