Glioblastoma: exosome and microRNA as novel diagnosis biomarkers

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834 · see citing works

Tumour exosome integrins determine organotropic metastasis

Hoshino, A., Costa-Silva, B., Shen, T.-L., Rodrigues, G., Hashimoto, A., Tesic Mark, M., Molina, H., Kohsaka, S., Di Giannatale, A., Ceder, S., et al. (2015) · Nature · doi:10.1038/nature15756 · Cited by 5,101 · see citing works

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Skog, J., Würdinger, T., van Rijn, S., Meijer, D. H., Gainche, L., Curry, W. T., Carter, B. S., Krichevsky, A. M., & Breakefield, X. O. (2008) · Nature Cell Biology · doi:10.1038/ncb1800 · Cited by 5,001 · see citing works

Extensive modulation of a set of microRNAs in primary glioblastoma

Ciafrè, S. A., Galardi, S., Mangiola, A., Ferracin, M., Liu, C.-G., Sabatino, G., Negrini, M., Maira, G., Croce, C. M., & Farace, M. G. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.07.030 · Cited by 1,096 · see citing works

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

Nilsson, J. A., Skog, J., Nordstrand, A., Baranov, V. I., Mincheva‐Nilsson, L., Breakefield, X. O., & Widmark, A. (2009) · British Journal of Cancer · doi:10.1038/sj.bjc.6605058 · Cited by 771 · see citing works

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

Silber, J., Lim, D. A., Petritsch, C., Persson, A. I., Maunakea, A. K., Yu, M., Vandenberg, S. R., Ginzinger, D. G., James, C. D., Costello, J. F., et al. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-14 · Cited by 765 · see citing works

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

Shao, H., Chung, J., Balaj, L., Charest, A., Bigner, D. D., Carter, B. S., Hochberg, F. H., Breakefield, X. O., Weissleder, R., & Lee, H. (2012) · Nature Medicine · doi:10.1038/nm.2994 · Cited by 757 · see citing works

Body fluid derived exosomes as a novel template for clinical diagnostics

Keller, S., Ridinger, J., Rupp, A.-K., Janssen, J. W. G., & Altevogt, P. (2011) · Journal of Translational Medicine · doi:10.1186/1479-5876-9-86 · Cited by 752 · see citing works

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

Kefas, B. A., Godlewski, J. A., Comeau, L., Li, Y., Abounader, R., Hawkinson, M. P., Lee, J., Fine, H. A., Chiocca, E. A., Lawler, S. E., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-6639 · Cited by 742 · see citing works

Altered Expression of miR-21, miR-31, miR-143 and miR-145 Is Related to Clinicopathologic Features of Colorectal Cancer

Slabý, O., Svoboda, M., Fabián, P., Šmerdová, T., Knoflíčková, D., Bednaříková, M., Nenutil, R., & Vyzula, R. (2007) · Oncology · doi:10.1159/000113489 · Cited by 682 · see citing works

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA

Guescini, M., Genedani, S., Stocchi, V., & Agnati, L. F. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0288-8 · Cited by 662 · see citing works

RNA-quality control by the exosome

Houseley, J. M., LaCava, J., & Tollervey, D. W. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1964 · Cited by 645 · see citing works

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

Shao, H., Chung, J., Lee, K., Balaj, L., Min, C., Carter, B. S., Hochberg, F. H., Breakefield, X. O., Lee, H., & Weissleder, R. (2015) · Nature Communications · doi:10.1038/ncomms7999 · Cited by 613 · see citing works

Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers

Alvarez, M. L., Khosroheidari, M., Ravi, R. K., & DiStefano, J. K. (2012) · Kidney International · doi:10.1038/ki.2012.256 · Cited by 578 · see citing works

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

Munoz, J. L., Bliss, S. A., Greco, S. J., Ramkissoon, S. H., Ligon, K. L., & Rameshwar, P. (2013) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2013.60 · Cited by 520 · see citing works

Glioblastoma: From Molecular Pathology to Targeted Treatment

Cloughesy, T. F., Cavenee, W. K., & Mischel, P. S. (2011) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130324 · Cited by 513 · see citing works

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivoPreprint

Huse, J. T., Brennan, C., Hambardzumyan, D., Wee, B., Pena, J., Rouhanifard, S. H., Sohn-Lee, C., le Sage, C., Agami, R., Tuschl, T., et al. (2009) · Genes & Development · doi:10.1101/gad.1777409 · Cited by 511 · see citing works

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease

Miranda, K. C., Bond, D. T., McKee, M. L., Skog, J., Păunescu, T. G., Silva, N. D., Brown, D., & Russo, L. M. (2010) · Kidney International · doi:10.1038/ki.2010.106 · Cited by 409 · see citing works

Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?

Bellingham, S. A., Guo, B. B., Coleman, B. M., & Hill, A. F. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00124 · Cited by 355 · see citing works

Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

Valentine, R., Dawson, W. O., Hu, C., Shah, K. M., Owen, T. J., Date, K. L., Pinheiro-Maia, S., Shao, J., Arrand, J. R., Young, L. S., et al. (2010) · Molecular Cancer · doi:10.1186/1476-4598-9-1 · Cited by 353 · see citing works

Biological gene delivery vehicles: beyond viral vectors.

Seow, Y., & Wood, M. (2009) · Molecular Therapy · doi:10.1038/mt.2009.41 · Cited by 339 · see citing works

miR-21 in the Extracellular Vesicles (EVs) of Cerebrospinal Fluid (CSF): A Platform for Glioblastoma Biomarker Development

Akers, J. C., Ramakrishnan, V., Kim, R., Skog, J., Nakano, I., Pingle, S. C., Kalinina, J., Hua, W., Kesari, S., Mao, Y. Q., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078115 · Cited by 335 · see citing works

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

Zhang, C., Zhang, J., Zhang, A., Shi, Z., Han, L., Jia, Z.-F., Yang, W., Wang, G., Jiang, T., You, Y., et al. (2010) · Molecular Cancer · doi:10.1186/1476-4598-9-229 · Cited by 314 · see citing works

A randomised controlled trial of a theory-based intervention to improve sun protective behaviour in adolescents ('you can still be HOT in the shade'): study protocol

Hawkes, A. L., Hamilton, K., White, K. M., & Young, R. M. (2012) · BMC Cancer · doi:10.1186/1471-2407-12-1 · Cited by 312 · see citing works

microRNA-34a is tumor suppressive in brain tumors and glioma stem cells

Guessous, F., Zhang, Y., Kofman, A., Catania, A., Li, Y., Schiff, D., Purow, B. W., & Abounader, R. (2010) · Cell Cycle · doi:10.4161/cc.9.6.10987 · Cited by 306 · see citing works

A Systematic Review of MicroRNA in Glioblastoma Multiforme: Micro-modulators in the Mesenchymal Mode of Migration and Invasion

Møller, H. G., Rasmussen, A. P., Andersen, H. H., Johnsen, K. B., Henriksen, M., & Duroux, M. C. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8349-7 · Cited by 266 · see citing works

Curcumin: A new candidate for melanoma therapy?

Mirzaei, H., Naseri, G., Rezaee, R., Mohammadi, M., Banikazemi, Z., Mirzaei, H. R., Salehi, H., Peyvandi, M., Pawelek, J. M., & Sahebkar, A. (2016) · International Journal of Cancer · doi:10.1002/ijc.30224 · Cited by 254 · see citing works

miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma

Wei, J., Wang, F., Kong, L.-Y., Xu, S., Doucette, T. A., Ferguson, S. D., Yang, Y., McEnery, K., Jethwa, K. R., Gjyshi, O., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-4318 · Cited by 253 · see citing works

Exosomes as nano-theranostic delivery platforms for gene therapy

Tan, A., Rajadas, J., & Seifalian, A. M. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.06.014 · Cited by 244 · see citing works

miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis

Smits, M., Nilsson, J. A., Mir, S. E., van der Stoop, P. M., Hulleman, E., Niers, J. M., Hamer, P. C. D. W., Márquez, V. E., Cloos, J. J., Krichevsky, A. M., et al. (2010) · Oncotarget · doi:10.18632/oncotarget.205 · Cited by 236 · see citing works

Cathepsin B: a potential prognostic marker for inflammatory breast cancer

Nouh, M. A., Mohamed, M. M., El‐Shinawi, M., Shaalan, M. A., Cavallo‐Medved, D., Khaled, H. M., & Sloane, B. F. (2011) · Journal of Translational Medicine · doi:10.1186/1479-5876-9-1 · Cited by 234 · see citing works

MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells

Gal, H., Pandi, G., Kanner, A. A., Ram, Z., Lithwick‐Yanai, G., Amariglio, N., Rechavi, G., & Givol, D. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.08.107 · Cited by 233 · see citing works

Ionizing Radiation and Glioblastoma Exosomes: Implications in Tumor Biology and Cell Migration

Arscott, W. T., Tandle, A. T., Zhao, S., Shabason, J. E., Gordon, I. K., Schlaff, C. D., Zhang, G., Tofilon, P. J., & Camphausen, K. A. (2013) · Translational Oncology · doi:10.1593/tlo.13640 · Cited by 229 · see citing works

miR-195, miR-455-3p and miR-10a∗ are implicated in acquired temozolomide resistance in glioblastoma multiforme cells

Ujifuku, K., Mitsutake, N., Takakura, S., Matsuse, M., Saenko, V., Suzuki, K., Hayashi, K., Matsuo, T., Kamada, K., Nagata, I., et al. (2010) · Cancer Letters · doi:10.1016/j.canlet.2010.04.013 · Cited by 226 · see citing works

Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of glioma

Wang, Q., Li, P., Li, A., Jiang, W., Wang, H., Wang, J., & Xie, K. (2012) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-31-97 · Cited by 202 · see citing works

The Exosome Is Recruited to RNA Substrates through Specific Adaptor Proteins

Thoms, M., Thomson, E., Baßler, J., Gnädig, M., Griesel, S., & Hurt, E. (2015) · Cell · doi:10.1016/j.cell.2015.07.060 · Cited by 192 · see citing works

Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases

Papagiannakopoulos, T. Y., Friedmann‐Morvinski, D., Neveu, P. A., Dugas, J. C., Gill, R. M., Huillard, E., Liu, C., Zong, H., Rowitch, D. H., Barres, B. A., et al. (2011) · Oncogene · doi:10.1038/onc.2011.380 · Cited by 188 · see citing works

MicroRNAs as potential diagnostic and prognostic biomarkers in melanoma

Mirzaei, H., Gholamin, S., Shahidsales, S., Sahebkar, A., Jaafari, M. R., Mirzaei, H. R., Hassanian, S. M., & Avan, A. (2015) · European Journal of Cancer · doi:10.1016/j.ejca.2015.10.009 · Cited by 183 · see citing works

Advanced health biotechnologies in Thailand: redefining policy directions

Velasco, R. P., Chaikledkaew, U., Myint, C. Y., Khampang, R., Tantivess, S., & Teerawattananon, Y. (2013) · Journal of Translational Medicine · doi:10.1186/1479-5876-11-1 · Cited by 182 · see citing works

MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3

Zheng, X., Chopp, M., Lü, Y., Buller, B., & Jiang, F. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.10.026 · Cited by 168 · see citing works

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients

Qiu, S., Lin, S., Hu, D., Feng, Y., Tan, Y., & Peng, Y. (2013) · Journal of Translational Medicine · doi:10.1186/1479-5876-11-10 · Cited by 166 · see citing works

Reduced expression of tissue factor pathway inhibitor-2 contributes to apoptosis and angiogenesis in cervical cancer

Zhang, Q., Zhang, Y., Wang, S. Z., Wang, N., Jiang, W. G., Ji, Y. H., & Zhang, S. L. (2012) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-31-1 · Cited by 164 · see citing works

Regulated microRNAs in the CSF of patients with multiple sclerosis

Haghikia, A., Haghikia, A., Hellwig, K., Baraniskin, A., Holzmann, A., Décard, B. F., Thum, T., & Gold, R. (2012) · Neurology · doi:10.1212/wnl.0b013e3182759621 · Cited by 160 · see citing works

Oncogenic effects of miR-10b in glioblastoma stem cells

Guessous, F., Alvarado‐Velez, M., Marcinkiewicz, L., Zhang, Y., Kim, J., Heister, S., Kefas, B. A., Godlewski, J. A., Schiff, D., Purow, B. W., et al. (2013) · Journal of Neuro-Oncology · doi:10.1007/s11060-013-1047-0 · Cited by 158 · see citing works

MiR‐195, miR‐196b, miR‐181c, miR‐21 expression levels and O‐6‐methylguanine‐DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

Lakomý, R., Šáňa, J., Hankeová, S., Fadrus, P., Křen, L., Lžičařová, E., Svoboda, M., Doleželová, H., Smrčka, M., Vyzula, R., et al. (2011) · Cancer Science · doi:10.1111/j.1349-7006.2011.02092.x · Cited by 155 · see citing works

Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers

Mirzaei, H. R., Sahebkar, A., Mohammadi, M., Yari, R., Salehi, H., Jafari, M., Namdar, A., Khabazian, E., Jaafari, M. R., & Mirzaei, H. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666160303110838 · Cited by 150 · see citing works

MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells

Xia, H., Qi, Y., Ng, S. S., Chen, X., Chen, S., Fang, M., Li, D., Zhao, Y. F., Ge, R., Guo, L., et al. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.12.169 · Cited by 147 · see citing works

Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-like Phenotype

Ying, Z., Li, Y., Wu, J., Zhu, X., Yang, Y., Tian, H., Li, W., Hu, B., Cheng, S., & Li, M. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-2895 · Cited by 146 · see citing works

MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme

Suh, S.-S., Yoo, J. Y., Nuovo, G. J., Jeon, Y.-J., Kim, S., Lee, T. J., Kim, T., Bakàcs, A., Alder, H., Kaur, B., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1202465109 · Cited by 144 · see citing works

MicroRNA involvement in glioblastoma pathogenesis

Nováková, J., Slabý, O., Vyzula, R., & Michálek, J. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.06.034 · Cited by 141 · see citing works

Glioblastoma: A Pathogenic Crosstalk between Tumor Cells and Pericytes

Caspani, E. M., Crossley, P. H., Redondo-Garcia, C., & Martı́nez, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101402 · Cited by 137 · see citing works

Identification of MMP-9 specific microRNA expression profile as potential targets of anti-invasion therapy in glioblastoma multiforme

Yan, W., Zhang, W., Sun, L., Liu, Y., You, G., Wang, Y., Kang, C., You, Y., & Jiang, T. (2011) · Brain Research · doi:10.1016/j.brainres.2011.07.002 · Cited by 134 · see citing works

Epi-Drugs and Epi-miRs: Moving Beyond Current Cancer Therapies

Salarinia, R., Sahebkar, A., Peyvandi, M., Mirzaei, H. R., Jaafari, M. R., Riahi, M. M., Ebrahimnejad, H., Nahand, J. S., Hadjati, J., Asrami, M. O., et al. (2016) · Current Cancer Drug Targets · doi:10.2174/1568009616666151207110143 · Cited by 134 · see citing works

Radiation-Induced Micro-RNA Modulation in Glioblastoma Cells Differing in DNA-Repair Pathways

Chaudhry, M. A., Sachdeva, H., & Omaruddin, R. A. (2010) · DNA and Cell Biology · doi:10.1089/dna.2009.0978 · Cited by 131 · see citing works

microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma

Kim, J., Zhang, Y., Skalski, M., Hayes, J. L., Kefas, B. A., Schiff, D., Purow, B. W., Parsons, S. J., Lawler, S. E., & Abounader, R. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-1449 · Cited by 127 · see citing works

MicroRNA expression profiling identifies miR-328 regulates cancer stem cell-like SP cells in colorectal cancer

Xu, X., Xu, Q., Tong, J., Zhu, M., Nie, F., Chen, X., Xiao, S., & Ran, Z. H. (2012) · British Journal of Cancer · doi:10.1038/bjc.2012.88 · Cited by 123 · see citing works

MiR‐136 promotes apoptosis of glioma cells by targeting AEG‐1 and Bcl‐2

Yang, Y., Wu, J., Guan, H., Cai, J., Fang, L., Li, J., & Li, M. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.08.003 · Cited by 121 · see citing works

VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling

Chen, L., Han, L., Zhang, K., Shi, Z., Zhang, J., Zhang, A., Wang, Y., Song, Y., Li, Y., Jiang, T., et al. (2012) · Neuro-Oncology · doi:10.1093/neuonc/nos122 · Cited by 118 · see citing works

cAMP response element-binding protein promotes gliomagenesis by modulating the expression of oncogenic microRNA-23a

Tan, X., Wang, S., Zhu, L., Wu, C., Yin, B., Zhao, J., Yuan, J., Qiang, B., & Peng, X. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1207787109 · Cited by 117 · see citing works

miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase

Wang, K., Wang, X., Zou, J., Zhang, A., Wan, Y., Pu, P., Song, Z., Qian, C., Chen, Y., Yang, S., et al. (2013) · Neuro-Oncology · doi:10.1093/neuonc/not004 · Cited by 117 · see citing works

STAT3 Regulation of Glioblastoma Pathogenesis

de la Iglesia, N., Puram, S. V., & Bonni, A. (2009) · Current Molecular Medicine · doi:10.2174/156652409788488739 · Cited by 117 · see citing works

Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth

Tang, H., Liu, X., Wang, Z., She, X., Zeng, X., Deng, M., Liao, Q., Guo, X., Wang, R., Li, X., et al. (2011) · Brain Research · doi:10.1016/j.brainres.2011.03.034 · Cited by 102 · see citing works

Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

Li, X., Liu, Y., Granberg, K. J., Wang, Q., Moore, L. M., Ji, P., Gumin, J., Sulman, E. P., Calin, G. A., Haapasalo, H., et al. (2015) · Oncogene · doi:10.1038/onc.2014.98 · Cited by 99 · see citing works

The CREB-miR-9 Negative Feedback Minicircuitry Coordinates the Migration and Proliferation of Glioma Cells

Tan, X., Wang, S., Yang, B., Zhu, L., Yin, B., Chao, T., Zhao, J., Yuan, J., Qiang, B., & Peng, X. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049570 · Cited by 98 · see citing works

MiR-410 regulates MET to influence the proliferation and invasion of glioma

Chen, L., Zhang, J., Feng, Y., Li, R., Sun, X., Du, W., Piao, X., Wang, H., Yang, D., Sun, Y., et al. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.06.027 · Cited by 95 · see citing works

MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation

Delic, S., Lottmann, N., Stelzl, A., Liesenberg, F., Wolter, M., Götze, S., Zapatka, M., Shiio, Y., Sabel, M., Felsberg, J., et al. (2013) · Neuro-Oncology · doi:10.1093/neuonc/not164 · Cited by 89 · see citing works

miR‐125b regulates the proliferation of glioblastoma stem cells by targeting E2F2

Wu, N., Xiao, L., Zhao, X., Zhao, J., Wang, J., Wang, F., Cao, S., & Lin, X. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.08.023 · Cited by 86 · see citing works

The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatment

Gholamin, S., Pasdar, A., Khorrami, M. S., Mirzaei, H., Mirzaei, H. R., Salehi, R., Ferns, G. A., Ghayour‐Mobarhan, M., & Avan, A. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612822666151112151924 · Cited by 85 · see citing works

MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status

Yang, G., Zhang, R., Chen, X., Mu, Y., Ai, J., Chen, S., Liu, Y., Shi, C., Sun, L., Rainov, N. G., et al. (2011) · Journal of Molecular Medicine · doi:10.1007/s00109-011-0775-x · Cited by 83 · see citing works

Low birthweight and preterm birth in young people with special educational needs: a magnetic resonance imaging analysis

Spencer, M. D., Moorhead, T. W. J., Gibson, R. J., McIntosh, A. M., Sussmann, J. E., Owens, D. G. C., Lawrie, S. M., & Johnstone, E. C. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-1 · Cited by 78 · see citing works

MiR‐483–5p suppresses the proliferation of glioma cells via directly targeting ERK1

Wang, L., Shi, M., Hou, S., Ding, B., Liu, L., Ji, X., Zhang, J., & Deng, Y. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.03.035 · Cited by 77 · see citing works

MicroRNAs and glioblastoma: roles in core signalling pathways and potential clinical implications

Šáňa, J., Hajdúch, M., Michálek, J., Vyzula, R., & Slabý, O. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01317.x · Cited by 69 · see citing works

MiR-24 regulates the proliferation and invasion of glioma by ST7L via β-catenin/Tcf-4 signaling

Chen, L., Zhang, A., Li, Y., Zhang, K., Han, L., Du, W., Yan, W., Li, R., Wang, Y., Wang, K., et al. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.10.025 · Cited by 68 · see citing works

MiR-328 Expression Is Decreased in High-Grade Gliomas and Is Associated with Worse Survival in Primary Glioblastoma

Wu, Z., Sun, L., Wang, H., Yao, J.-S., Jiang, C., Xu, W., & Yang, Z. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047270 · Cited by 60 · see citing works

Serial selection for invasiveness increases expression of miR-143/miR-145 in glioblastoma cell lines

Koo, S., Martin, G. S., Schulz, K. J., Ronck, M., & Toussaint, L. G. (2012) · BMC Cancer · doi:10.1186/1471-2407-12-143 · Cited by 53 · see citing works

MiR-330-Mediated Regulation of SH3GL2 Expression Enhances Malignant Behaviors of Glioblastoma Stem Cells by Activating ERK and PI3K/AKT Signaling Pathways

Yao, Y., Xue, Y., Ma, J., Shang, C., Wang, P., Liu, L., Liu, W., Li, Z., Qu, S., Li, Z., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095060 · Cited by 53 · see citing works

Differential Effects of MicroRNAs on Glioblastoma Growth and Migration

Jeansonne, D. P., Pacifici, M., Lassak, A., Krzysztof Reiss, F., Russo, G. M., Zabaleta, J., & Peruzzi, F. (2013) · Genes · doi:10.3390/genes4010046 · Cited by 21 · see citing works

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Cheshmi, H. (2011) · New Cellular and Molecular Biotechnology Journal · Cited by 2 · see citing works

Integrating liquid biopsies into the management of cancer

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Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance

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Plasminogen Activator Inhibitor Type‐1 as a Regulator of Fibrosis

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Stroke in Women: Risk Factors and Clinical Biomarkers

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Cytokines and MicroRNA in Coronary Artery Disease

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MiRNA-451 Inhibits Glioma Cell Proliferation and Invasion Through the mTOR/HIF-1α/VEGF Signaling Pathway by Targeting CAB39

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miRNA-Based Strategy for Modulation of Influenza A Virus Infection

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Exosomal microRNA and stroke: A review

Ghoreishi, A., Khosravi, A., & Ghaemmaghami, A. B. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.29130 · Cited by 42 · see citing works

Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2

Qian, C., Wang, Y., Ji, Y., Chen, D., Wang, C., Zhang, G., & Wang, Y. (2022) · International Journal of Oncology · doi:10.3892/ijo.2022.5405 · Cited by 42 · see citing works

Vaccines for colorectal cancer: an update

Sarvizadeh, M., Ghasemi, F., Tavakoli, F., Khatami, S. S., Razi, E., Sharifi, H., Mousavi, N., & Taghizadeh, M. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28179 · Cited by 41 · see citing works

MicroRNA and exosome: Key players in rheumatoid arthritis

Zakeri, Z., Salmaninejad, A., Hosseini, N., Shahbakhsh, Y., Fadaee, E., Shahrzad, M. K., & Fadaei, S. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28499 · Cited by 42 · see citing works

Profiling of novel circulating microRNAs as a non-invasive biomarker in diagnosis and follow-up of high and low-grade gliomas

Tabibkhooei, A., Izadpanahi, M., Arab, A., Zare‐Mirzaie, A., Minaeian, S., Rostami, A., & Mohsenian, A. (2019) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2019.105652 · Cited by 41 · see citing works

Role of RNA-binding proteins during the late stages of Flavivirus replication cycle

Toro, M. D., Prasanth, K. R., Bradrick, S. S., & García-Blanco, M. A. (2020) · Virology Journal · doi:10.1186/s12985-020-01329-7 · Cited by 40 · see citing works

Therapeutically Significant MicroRNAs in Primary and Metastatic Brain Malignancies

Balachandran, A. A., Larcher, L. M., Chen, S., & Veedu, R. N. (2020) · Cancers · doi:10.3390/cancers12092534 · Cited by 41 · see citing works

Circulating microRNAs as potential diagnostic biomarkers and therapeutic targets in prostate cancer: Current status and future perspectives

Movahedpour, A., Ahmadi, N., Ghasemi, Y., Savardashtaki, A., & Shabaninejad, Z. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.29053 · Cited by 40 · see citing works

Cancer-testis antigen lactate dehydrogenase C4 in hepatocellular carcinoma: a promising biomarker for early diagnosis, efficacy evaluation and prognosis prediction

Cui, Z., Li, Y., Gao, Y., Kong, L., Lin, Y., & Chen, Y. (2020) · Aging · doi:10.18632/aging.103879 · Cited by 39 · see citing works

Extracellular vesicle-mediated regulation of macrophage polarization in bacterial infections

Qu, M., Zhu, H., & Zhang, X. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1039040 · Cited by 39 · see citing works

Exosomes: promising sacks for treating ischemic heart disease?

Chen, G.-H., Xu, J., & Yang, Y. (2017) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00213.2017 · Cited by 37 · see citing works

Modulation of Biological Activities in Glioblastoma Mediated by Curcumin

Trotta, T., Panaro, M. A., Prifti, E., & Porro, C. (2019) · Nutrition and Cancer · doi:10.1080/01635581.2019.1604978 · Cited by 37 · see citing works

NCAPG2 facilitates glioblastoma cells’ malignancy and xenograft tumor growth via HBO1 activation by phosphorylation

Wu, J., Li, L., Jiang, G., Zhan, H., Zhu, X., & Yang, W. (2020) · Cell and Tissue Research · doi:10.1007/s00441-020-03281-y · Cited by 37 · see citing works

Liquid Biopsy: the Value of Different Bodily Fluids

Santos, V., Freitas, C., Fernandes, M. G., Sousa, C., Reboredo, C., Martins, N. A., Mosquera, J., Hespanhol, V. P., & Campelo, R. G. (2022) · Biomarkers in Medicine · doi:10.2217/bmm-2021-0370 · Cited by 38 · see citing works

Ultracentrifugation Versus Kit Exosome Isolation: NanoLC–MS and Other Tools Reveal Similar Performance Biomarkers, But Also Contaminations

Skottvoll, F. S., Berg, H. E., Bj⊘rseth, K., Lund, K., Roos, N., Bekhradnia, S., Thiede, B., Sandberg, C. J., Vik-Mo, E. O., Røberg‐Larsen, H., et al. (2018) · Future Science OA · doi:10.4155/fsoa-2018-0088 · Cited by 36 · see citing works

Exploring the role of Nrf2 signaling in glioblastoma multiforme

Awuah, W. A., Abdul‐Rahman, T., Yarlagadda, R., Mikhailova, T., Mehta, A., Huang, H., Kundu, M., Lopes, L. A., Benson, S., Mykola, L., et al. (2022) · Discover Oncology · doi:10.1007/s12672-022-00556-4 · Cited by 36 · see citing works

MicroRNA-based integrated diagnosis and therapy for GBM: current status and advances

Chen, Y., Liu, H., Yuan, P., Liu, H., Xu, C., Li, R. Q., Chen, J., & Wu, F. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1806864 · Cited by 1 · see citing works

Roles of microRNAs carried by exosomes in glioblastoma microenvironment

Günay, A., Demirel, Z., Dinçkurt, N., Kopal, E., & Yerlikaya, P. O. (2025) · Human Gene · doi:10.1016/j.humgen.2025.201423 · Cited by 1 · see citing works

Advances in exosome-related biomarkers for glioblastoma: Basic research and clinical application

Chang, Q., Jiang, Y., Qian, J., Yang, J., Xiao-ling, Y. A. N., & Xue, X. (2018) · Glioma · doi:10.4103/glioma.glioma_35_18 · Cited by 3 · see citing works

Microcargos with Megaeffects: A Literature Review of Immunomodulatory, Diagnostic, Prognostic, and Therapeutic Dimensions of Exosomal MicroRNAs in Glioblastoma Multiforme

Kamroo, A., Esmaeili, A., Tahan, K., Shafizadeh, M., & Rezaei, N. (2025) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-025-01620-7 · Cited by 2 · see citing works

血漿エクソソーム由来microRNA を用いたグリオブラストーマ診断バイオマーカーの探索

Yamaguchi, K., Moriguchi, T., Yamashita, D., Ohnishi, T., Kaneko, S., Matoba, R., Kondo, T., & Tei, K. (2019) · Institutional Repositories DataBase (IRDB)