Complement and its role in innate and adaptive immune responses

Toll-like receptor control of the adaptive immune responses

Iwasaki, A., & Medzhitov, R. M. (2004) · Nature Immunology · doi:10.1038/ni1112 · Cited by 4,166

Immunobiology: the immune system in health and disease

(1995) · Choice Reviews Online · doi:10.5860/choice.32-3876 · Cited by 4,111

Approaching the asymptote? Evolution and revolution in immunology.Preprint

Janeway, C. (1989) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1989.054.01.003 · Cited by 3,396

Complement

Walport, M. J. (2001) · New England Journal of Medicine · doi:10.1056/nejm200104053441406 · Cited by 2,969

Decoding the Patterns of Self and Nonself by the Innate Immune System

Medzhitov, R., & Janeway, C. A. (2002) · Science · doi:10.1126/science.1068883 · Cited by 2,154

Anesthesiology

Wiklund, R. A., & Rosenbaum, S. H. (1997) · New England Journal of Medicine · doi:10.1056/nejm199710163371606 · Cited by 2,153

Innate Immunity

Medzhitov, R. M., & Janeway, C. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008033430506 · Cited by 1,827

Complement

Walport, M. J. (2001) · New England Journal of Medicine · doi:10.1056/nejm200104123441506 · Cited by 1,502

C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity

Dempsey, P. W., Allison, M. E. D., Akkaraju, S., Goodnow, C. C., & Fearon, D. T. (1996) · Science · doi:10.1126/science.271.5247.348 · Cited by 1,197

Pattern Recognition Receptors

Gordon, S. (2002) · Cell · doi:10.1016/s0092-8674(02)01201-1 · Cited by 1,153

Dysregulation of adaptive immune responses in complement C3‐deficient patients

Pekkarinen, P. T., Heikkilä, N., Kisand, K. E., Peterson, P., Botto, M., Daha, M. R., Drouet, C., Isaac, L., Helminen, M., Haahtela, T., et al. (2014) · European Journal of Immunology · doi:10.1002/eji.201444948 · Cited by 18

Oxidative stress in paroxysmal nocturnal hemoglobinuria and other conditions of complement-mediated hemolysis

Fibach, E., & Dana, M. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.04.027 · Cited by 18

The lectin pathway of complement: Advantage or disadvantage in HIV pathogenesis?

Ballegaard, V., Haugaard, A. K., Garred, P., Nielsen, S. D., & Munthe‐Fog, L. (2014) · Clinical Immunology · doi:10.1016/j.clim.2014.06.002 · Cited by 18

Bacterial composition and activity determines host gene-expression responses in gnotobiotic Atlantic cod (Gadus morhua) larvae

Forberg, T., Vestrum, R. I., Arukwe, A., & Vadstein, Ô. (2012) · Veterinary Microbiology · doi:10.1016/j.vetmic.2012.01.007 · Cited by 18

Targeted complement inhibition and microvasculature in transplants: a therapeutic perspective

Khan, M. A., Hsu, J. L., Assiri, A. M., & Broering, D. C. (2015) · Clinical & Experimental Immunology · doi:10.1111/cei.12713 · Cited by 18

The humoral immune systems of the American lobster (Homarus americanus) and the European lobster (Homarus gammarus)

Bowden, T. J. (2016) · Fisheries Research · doi:10.1016/j.fishres.2016.07.023 · Cited by 18

In VivoBiological Evaluation of High Molecular Weight Multifunctional Acid-Degradable Polymeric Drug Carriers with Structurally Different Ketals

Shenoi, R. A., Abbina, S., & Kizhakkedathu, J. N. (2016) · Biomacromolecules · doi:10.1021/acs.biomac.6b01198 · Cited by 18

Strategy and Tactics for Designing Analogs: Biochemical Characterization of the Large Molecules

Ahn, J., Kassees, K., Lee, T.-K., Manandhar, B., & Yousif, A. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.12413-8 · Cited by 20

Blocking Synthesis of the Variant Surface Glycoprotein Coat in Trypanosoma brucei Leads to an Increase in Macrophage Phagocytosis Due to Reduced Clearance of Surface Coat Antibodies

Cheung, J. L. Y., Wand, N. V., Ooi, C., Ridewood, S., Wheeler, R. J., & Rudenko, G. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1006023 · Cited by 18

Morgagnian cataract resulting from a naturally occurring nonsense mutation elucidates a role of CPAMD8 in mammalian lens development

Hollmann, A. K., Dammann, I., Wemheuer, W. M., Wemheuer, W., Chilla, A., Tipold, A., Schulz‐Schaeffer, W., Beck, J., Schütz, E., & Brenig, B. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180665 · Cited by 18

The liver proteome in a mouse model for Ascaris suum resistance and susceptibility: evidence for an altered innate immune response

Deslyper, G., Holland, C. V., Colgan, T. J., & Carolan, J. C. (2019) · Parasites & Vectors · doi:10.1186/s13071-019-3655-9 · Cited by 18

Complement system and phagocytosis in a colonial protochordate

Peronato, A., Drago, L., Rothbächer, U., Macor, P., Ballarin, L., & Franchi, N. (2019) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2019.103530 · Cited by 18

A review of the treatment landscape in paroxysmal nocturnal haemoglobinuria: where are we now and where are we going?

Griffin, M., Kelly, R., & Pike, A. (2020) · Therapeutic Advances in Rare Disease · doi:10.1177/2633004020959349 · Cited by 18

Quantitative proteomics analysis of Angiostrongylus vasorum-induced alterations in dog serum sheds light on the pathogenesis of canine angiostrongylosis

Tritten, L., Gillis-Germitsch, N., Kockmann, T., & Schnyder, M. (2021) · Scientific Reports · doi:10.1038/s41598-020-79459-9 · Cited by 19

The SARS-CoV-2/Receptor Axis in Heart and Blood Vessels: A Crisp Update on COVID-19 Disease with Cardiovascular Complications

Veluswamy, P., Wacker, M., Stavridis, D., Reichel, T., Schmidt, H., Scherner, M. P., Wippermann, J., & Michels, G. (2021) · Viruses · doi:10.3390/v13071346 · Cited by 18

Alterations of Plasma Galectin-3 and C3 Levels in Patients with Parkinson’s Disease

Wu, H.-C., Chang, K., Chiang, M.-C., & Chen, C. (2021) · Brain Sciences · doi:10.3390/brainsci11111515 · Cited by 19

Kidney diseases

Daina, E., Cortinovis, M., & Remuzzi, G. (2022) · Immunological Reviews · doi:10.1111/imr.13167 · Cited by 18

Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae

Aguinagalde, L., den Boer, M. A., Castenmiller, S. M., Zwarthoff, S. A., de Haas, C. J. C., Aerts, P. C., Beurskens, F. J. M., Schuurman, J., Heck, A. J. R., van Kessel, K. P. M., et al. (2023) · eLife · doi:10.7554/elife.80669 · Cited by 19

Comprehensive transcriptomic, proteomic, and intestinal microbiota analyses of largemouth bass (Micropterus salmoides) intestines reveal new insights into immune responses to Aeromonas hydrophila infection

Chen, F., Ouyang, X., Liao, Z., Huang, T., Tong, G., Tan, H., Zhou, M., Lu, X., Wei, X., Xue-ming, Y., et al. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.110057 · Cited by 17

Reduced Terminal Complement Complex Formation in Mice Manifests in Low Bone Mass and Impaired Fracture Healing

Mödinger, Y., Rapp, A. E., Vikman, A., Ren, Z., Fischer, V., Bergdolt, S., Haffner‐Luntzer, M., Song, W., Lambris, J. D., Huber-Lang, M. S., et al. (2018) · American Journal Of Pathology · doi:10.1016/j.ajpath.2018.09.011 · Cited by 17

What bacterial cell death teaches us about life

Johnson, A. G., & Kranzusch, P. J. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010879 · Cited by 19

The sex-dependent and enduring impact of pubertal stress on health and disease

Smith, K. B., Murack, M., & Ismail, N. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.110701 · Cited by 17

Cell-targeted vaccines: implications for adaptive immunity

Ung, T. W.-M., Rutledge, N. S., Weiss, A. M., Esser-Kahn, A. P., & Deak, P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1221008 · Cited by 19

Mycobacterium tuberculosis and its clever approaches to escape the deadly macrophage

Krishnan, V., Nath, S., Nair, P., & Das, B. (2023) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-023-03735-9 · Cited by 17

Toxicoproteomic analysis of pulmonary carbon nanotube exposure using LC-MS/MS

Hilton, G. M., Taylor-Just, A. J., McClure, C. D., Parsons, G. N., Bonner, J. C., & Bereman, M. S. (2015) · Toxicology · doi:10.1016/j.tox.2015.01.011 · Cited by 17

Revisiting the Concept of Targeting Only Bacillus anthracis Toxins as a Treatment for Anthrax

Glinert, I., Bar-David, E., Sittner, A., Weiss, S., Schlomovitz, J., Ben‐Shmuel, A., Mechaly, A., Altboum, Z., Kobiler, D., & Levy, H. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00546-16 · Cited by 17

Tongue sole ( Cynoglossus semilaevis ) CD59: A complement inhibitor that binds bacterial cells and promotes bacterial escape from the killing of fish serum

Sui, Z., Li, M.-F., & Sun, L. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.09.051 · Cited by 17

Glutathione inhibits antibody and complement-mediated immunologic cell injury via multiple mechanisms

Zhang, Z., Zhang, X., Fang, X., Niimi, M., Huang, Y., Piao, H., Gao, S., Fan, J., & Yao, J. Q. (2017) · Redox Biology · doi:10.1016/j.redox.2017.03.030 · Cited by 17

Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism

Høiland, I. I., Liang, R. A., Hindberg, K., Latysheva, N., Brekke, O., Mollnes, T. E., & Hansen, J. (2018) · Thrombosis Research · doi:10.1016/j.thromres.2018.06.019 · Cited by 17

Protective efficacy of Shilajit enriched diet on growth performance and immune resistance against Aeromonas hydrophila in Oreochromis mossambicus

Musthafa, M. S., Asgari, S. M., Elumalai, P., Hoseinifar, S. H., & Doan, H. V. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.08.022 · Cited by 17

Complement factor and T-cell interactions during alloimmune inflammation in transplantation

Khan, M. A., & Shamma, T. (2018) · Journal of Leukocyte Biology · doi:10.1002/jlb.5ru0718-288r · Cited by 19

Ficolin A derived from local macrophages and neutrophils protects against lipopolysaccharide‐induced acute lung injury by activating complement

Wu, X., Yao, D., Bao, L., Liu, D., Xu, X., An, Y., Zhang, X., & Cao, B. (2020) · Immunology and Cell Biology · doi:10.1111/imcb.12344 · Cited by 17

CD46 signaling in T cells: Linking pathogens with polarity

Hawkins, E. D., & Oliaro, J. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.09.003 · Cited by 17

A Novel Mutation in the Complement Component 3 Gene in a Patient with Selective IgA Deficiency

Santos-Valente, E., Reisli, İ., Artaç, H., Ott, R., Sanal, Ö., & Boztuǧ, K. (2012) · Journal of Clinical Immunology · doi:10.1007/s10875-012-9775-z · Cited by 17

Interactions Between the Complement System and Fcγ Receptors

Lindorfer, M. A., Köhl, J., & Taylor, R. P. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-394802-1.00003-0 · Cited by 18

A Single-Step Gold Nanoparticle–Blood Serum Interaction Assay Reveals Humoral Immunity Development and Immune Status of Animals from Neonates to Adults

Zheng, T., Crews, J., McGill, J. L., Dhume, K., Finn, C. M., Strutt, T. M., McKinstry, K. K., & Huo, Q. (2018) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.8b00213 · Cited by 17

Two alpha-2 macroglobulin from Portunus trituberculatus involved in the prophenoloxidase system, phagocytosis and regulation of antimicrobial peptides

Ning, J., Liu, Y., Gao, F., Song, C., & Cui, Z. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.04.033 · Cited by 17

Genome-wide identification, evolution, and mRNA expression of complement genes in common carp (Cyprinus carpio)

Lv, H., Zhou, T., Dong, C., Kong, S., Chen, L., Pu, F., Li, X., & Xu, P. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.11.032 · Cited by 19

Modulation of Iberian Ribbed Newt Complement Component C3 by Stressors Similar to those Encountered during a Stay Onboard the International Space Station

Guéguinou, N., Jeandel, J., Kaminski, S., Baatout, S., Ghislin, S., & Frippiat, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071579 · Cited by 17

At The Interface: Small-Molecule Inhibitors of Soluble Cytokines

Raavi, Koehler, A. N., & Vegas, A. J. (2025) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00469 · Cited by 18

Boosting Immunity Through Nutrition and Gut Health: A Narrative Review on Managing Allergies and Multimorbidity

Andreou, E. P., & Papaneophytou, C. P. (2025) · Nutrients · doi:10.3390/nu17101685 · Cited by 19

Klebsiella pneumoniae: Host interactions, virulence mechanisms, and novel therapeutic strategies

Abhinand, K., Menon, A. M., Thomas, S. S., Anil, A. B., Mohanan, P. C. P., Arun, K. B., Edison, L. K., Babu, P., Kumar, G. B., Nair, B. G., et al. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107856 · Cited by 18

Vaccination with LetiFend® reduces circulating immune complexes in dogs experimentally infected with L. infantum

Cacheiro‐Llaguno, C., Parody, N., Renshaw-Calderón, A., Osuna, C., Alonso‐Moreno, C., & Carnés, J. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.10.078 · Cited by 16

Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma

Panaampon, J., Kariya, R., & Okada, S. (2021) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-021-03054-8 · Cited by 16

Molecularly-imprinted hydrogel beads via self-sacrificing micro-reactors as safe and selective bilirubin adsorbents

Yin, S., Xu, Y., Wang, Z., Wei, Z., Xu, T., Zhao, W., & Zhao, C. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb01895g · Cited by 16

Machine Learning-Based Identification of Potentially Novel Non-Alcoholic Fatty Liver Disease Biomarkers

Shafiha, R., Bahcivanci, B., Gkoutos, G. V., & Acharjee, A. (2021) · Biomedicines · doi:10.3390/biomedicines9111636 · Cited by 16

The complement system and complement-like factors in sea cucumber

Xiao, K., Zhang, S., & Li, C. (2022) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2022.104511 · Cited by 16

Immunomodulatory potential of apolipoproteins and their mimetic peptides in asthma: Current perspective

Ghosh, S., Rihan, M., Ahmed, S., Pande, A. H., & Sharma, S. S. (2022) · Respiratory Medicine · doi:10.1016/j.rmed.2022.107007 · Cited by 18

Stress, psychiatric disease, and obesity: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022

Christensen, S. M., Varney, C., Gupta, V., Wenz, L., & Bays, H. E. (2022) · Obesity Pillars · doi:10.1016/j.obpill.2022.100041 · Cited by 16

Proteomics Analysis of Plasma-Derived Exosomes Unveils the Aberrant Complement and Coagulation Cascades in Dermatomyositis/Polymyositis

Meng, S., Wang, T., Zhao, Q., Hu, Q., Chen, Y., Li, H., Liu, C., Liu, D. J., & Hong, X. (2022) · Journal of Proteome Research · doi:10.1021/acs.jproteome.2c00532 · Cited by 16

Activation of the Complement and Coagulation Systems in the Small Airways in Asthma

Kokelj, S., Östling, J., Fromell, K., Vanfleteren, L. E. G. W., Olsson, H., Ekdahl, K. N., Nilsson, B., & Olin, A. (2023) · Respiration · doi:10.1159/000531374 · Cited by 18

Circulatory HMGB1 is an early predictive and prognostic biomarker of ARDS and mortality in a swine model of polytrauma

Young, M. D., Cancio, T. S., Thorpe, C. R., Willis, R. P., Snook, J. K., Jordan, B. S., Demons, S. T., Salinas, J., & Yang, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1227751 · Cited by 17

The Role of Peritoneal Immunity in Peritoneal Endometriosis and Related Infertility

Huang, Q., Yu, Y., Xu, W., Li, S., Zhou, Y., & Shu, J. (2023) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2808166 · Cited by 19

Imaging geographic atrophy: integrating structure and function to better understand the effects of new treatments

Vujosevic, S., Loewenstein, A., O’Toole, L., Schmidt-Erfurth, U. M., Zur, D., & Chakravarthy, U. (2024) · British Journal of Ophthalmology · doi:10.1136/bjo-2023-324246 · Cited by 16

Recurrent C3 glomerulopathy after kidney transplantation

Obata, S., de Castro, P. A. S. V., Riella, L. V., & Cravedi, P. (2024) · Transplantation Reviews · doi:10.1016/j.trre.2024.100839 · Cited by 16

Double-Edged Sword: Exploring the Mitochondria–Complement Bidirectional Connection in Cellular Response and Disease

Lin, J., Hwang, S., Luo, H., & Mohamud, Y. (2024) · Biology · doi:10.3390/biology13060431 · Cited by 16

Gene therapy for the leukodystrophies: From preclinical animal studies to clinical trials.

Metovic, J., Li, Y., Gong, Y., & Eichler, F. (2024) · Neurotherapeutics · doi:10.1016/j.neurot.2024.e00443 · Cited by 16

Bead Arrays for Antibody and Complement Profiling Reveal Joint Contribution of Antibody Isotypes to C3 Deposition

Ayoglu, B., Szarka, E., Huber, K., Orosz, A., Babos, F., Magyar, A., Hudecz, F., Rojkovich, B., Gáti, T., Nagy, G., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096403 · Cited by 16

The role of complement regulatory proteins in peripheral blood cells of patients with systemic lupus erythematosus: Review

Alegretti, A. P., Schneider, L., Piccoli, A. K., & Xavier, R. M. (2012) · Cellular Immunology · doi:10.1016/j.cellimm.2012.06.008 · Cited by 16

Serum ficolin-2 concentrations are significantly changed in patients with hepatitis B virus infection and liver diseases

Chen, T., Hu, Y., Ding, Q., Yu, J., Wang, X., Luo, F., & Zhang, X. (2015) · Virologica Sinica · doi:10.1007/s12250-015-3605-4 · Cited by 16

Mutational analysis of Kaposica reveals that bridging of MG2 and CUB domains of target protein is crucial for the cofactor activity of RCA proteins

Gautam, A. K., Panse, Y., Ghosh, P., Reza, M. J., Mullick, J., & Sahu, A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1506449112 · Cited by 16

Fluid phase recognition molecules in neutrophil-dependent immune responses

Jaillon, S., Ponzetta, A., Magrini, E. I., Barajon, I., Barbagallo, M., Garlanda, C., & Mantovani, A. (2016) · Seminars in Immunology · doi:10.1016/j.smim.2016.03.005 · Cited by 16

Characterizing the effect of multiple Fc glycan attributes on the effector functions and FcγRIIIa receptor binding activity of an IgG1 antibody

Pace, D. L., Lewis, N. E., Wu, T. J.-T., Gillespie, R., Dan, L., Velayudhan, J., Rohrbach, A. S., & Connell‐Crowley, L. (2016) · Biotechnology Progress · doi:10.1002/btpr.2300 · Cited by 17

Immune response in common carp (Cyprinus carpioL.) following glyphosate-exposure

Ma, J., Feng, Y., Xie, W., Yang, L., & Li, X. (2015) · Toxin Reviews · doi:10.3109/15569543.2015.1133647 · Cited by 16

Notch1a can widely mediate innate immune responses in zebrafish larvae infected with Vibrio parahaemolyticus

Ji, C., Guo, X., Dong, X., Ren, J., Zu, Y., Li, W., & Zhang, Q. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.06.058 · Cited by 16

A new case of congenital ficolin-3 deficiency with primary immunodeficiency

Babaha, F., Abolhassani, H., Esfahani, Z. H., Yazdani, R., & Aghamohammadi, A. (2020) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2020.1792779 · Cited by 16

Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction

Mizuno, M., Khaledian, B., Maeda, M., Hayashi, T., Mizuno, S., Munetsuna, E., Watanabe, T., Kono, S., Okada, S., Suzuki, M., et al. (2021) · Cancers · doi:10.3390/cancers13164238 · Cited by 16

The role of complement C3 in the outcome of regional myocardial infarction

Fang, Z., Li, X., Liu, J., Lee, H., Salciccioli, L. F., Lazar, J., & Zhang, M. (2023) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2023.101434 · Cited by 16

Exogenous C3 Postpones Complement Exhaustion and Confers Organ Protection in Murine Sepsis

Yuan, Y., Ren, J., Wu, X., Cao, S., & Li, J. (2011) · Journal of Surgical Research · doi:10.1016/j.jss.2011.01.062 · Cited by 16

Mannose-binding lectin polymorphisms and rheumatoid arthritis: A short review and meta-analysis

Boschmann, S. E., Goeldner, I., Tuon, F. F., Schiel, W. A., Aoyama, F., & Messias-Reason, I. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.10.010 · Cited by 16

Comparative Proteomic Profiling and Biomarker Identification of Traditional Chinese Medicine-Based HIV/AIDS Syndromes

Wen, L., Liu, Y., Jiang, C., Zeng, S., Su, Y., Wu, W., Liu, X.-Y., Wang, J., Liu, Y., Su, C. H., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-22611-3 · Cited by 16

Complement C3 and incident hospitalization due to chronic kidney disease: a population-based cohort study

Bao, X., Borné, Y., Muhammad, I. F., Schulz, C., Persson, M., Orho‐Melander, M., Niu, K., Christensson, A. G., & Engström, G. (2019) · BMC Nephrology · doi:10.1186/s12882-019-1248-7 · Cited by 16

A Novel C1-Esterase Inhibitor Oxygenator Coating Prevents FXII Activation in Human Blood

Gerling, K., Ölschläger, S., Avci‐Adali, M., Neumann, B., Schweizer, E., Schlensak, C., Wendel, H.-P., & Stoppelkamp, S. (2020) · Biomolecules · doi:10.3390/biom10071042 · Cited by 16

Complement and systemic lupus erythematosus

Liu, C., Manzi, S., & Ahearn, J. M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-93232-5.00026-5 · Cited by 16

Immune Regulatory Crosstalk in Adipose Tissue Thermogenesis

Yildiz, R., Ganbold, K., Sparman, N. Z. R., & Rajbhandari, P. (2025) · Comprehensive physiology · doi:10.1002/cph4.70001 · Cited by 17

Understanding the Mechanism of Cardiotoxicity Induced by Nanomaterials: A Comprehensive Review

Zheng, Z., Zhu, S., Wang, X., Wu, H., Fu, M., Hu, H., Gu, Z., & Zhang, C. (2025) · Small Science · doi:10.1002/smsc.202400498 · Cited by 21

Multimodal sequencing of neoadjuvant nivolumab treatment in hepatocellular carcinoma reveals cellular and molecular immune landscape for drug response

Zeng, F., Zhang, Q., Tsui, Y., Ma, H., Tian, L., Husain, A., Lu, J., Lee, J. M., Zhang, V. X., Li, P.-M., et al. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02314-w · Cited by 19

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Woodworth, K. E., Callaghan, N. I., & Huyer, L. D. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202508761 · Cited by 16

Monoclonal Antibodies: Historical Perspective and Current Trends in Biological Drug Development

Madej, B., Tomaszewski, F., Szmajda‐Krygier, D., Świechowski, R., Jeleń, A. M., & Mirowski, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26188794 · Cited by 15

Natural products provide a new perspective for anti-complement treatment of severe COVID-19: a review

Fan, Y., Wang, Y., Yu, S., Chang, J. B. P., Yan, Y., Wang, Y., & Bian, Y. (2021) · Chinese Medicine · doi:10.1186/s13020-021-00478-3 · Cited by 15

Tumor Temporal Proteome Profiling Reveals the Immunological Triple Offensive Induced by Synthetic Anti-Cancer Salmonella

Yang, S., Zhao, W., Zhu, M., Hu, H., Wang, W., Zang, Z., Jin, M., Bi, J., Huang, J., Liu, C., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.712936 · Cited by 15

Screening of Surface-Exposed Lipoproteins of Leptospira Involved in Modulation of Host Innate Immune Response

Kumar, A., Varma, V. P., & Faisal, S. M. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.761670 · Cited by 15

Immunometabolic Signature during Respiratory Viral Infection: A Potential Target for Host-Directed Therapies

dos Reis, L. M., Berçot, M. R., Castelucci, B. G., Martins, A. J. E., Castro, G., & Moraes‐Vieira, P. M. (2023) · Viruses · doi:10.3390/v15020525 · Cited by 17

Challenge of material haemocompatibility for microfluidic blood-contacting applications

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