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Uemura, S., Mochizuki, T., Amemiya, K., Kurosaka, G., Yazawa, M., Nakamoto, K., Ishikawa, Y., Izawa, S., & Abe, F. (2020) · Journal of Cell Science · doi:10.1242/jcs.245555 · Cited by 12 · see citing works

Feedback regulation of TORC1 by its downstream effectors Npr1 and Par32

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C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly

Rasheed, N., Lima, T. B., Mercaldi, G. F., Nascimento, A. F. Z., Silva, A. L. S., Righetto, G. L., Bar‐Peled, L., Shen, K., Sabatini, D. M., Gozzo, F. C., et al. (2019) · FEBS Open Bio · doi:10.1002/2211-5463.12700 · Cited by 12 · see citing works

TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89

Nicastro, R., Gulli, M., Caligaris, M., Jaquenoud, M., Dokládal, L., Alba, J., Tripodi, F., Pillet, B., Brunner, M., Stumpe, M., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115683 · Cited by 10 · see citing works

Conserved Pib2 regions have distinct roles in TORC1 regulation at the vacuole

Troutman, K. K., Varlakhanova, N. V., Tornabene, B. A., Ramachandran, R., & Ford, M. G. J. (2022) · Journal of Cell Science · doi:10.1242/jcs.259994 · Cited by 10 · see citing works

TOR Signaling in Budding Yeast

Inoue, Y., & Nomura, W. (2018) · InTech eBooks · doi:10.5772/intechopen.70784 · Cited by 10 · see citing works

The yeast cell wall protein Pry3 inhibits mating through highly conserved residues within the CAP domain

Cottier, S., Darwiche, R., Meyenhofer, F., Debelyy, M. O., & Schneiter, R. (2020) · Biology Open · doi:10.1242/bio.053470 · Cited by 9 · see citing works

Analysis of the TORC1 interactome reveals a spatially distinct function of TORC1 in mRNP complexes

Chang, Y., Lim, G., & Huh, W. (2021) · The Journal of Cell Biology · doi:10.1083/jcb.201912060 · Cited by 8 · see citing works

Overexpression of smORF YNR034W-A/EGO4 in Saccharomyces cerevisiae increases the fermentative efficiency of Agave tequilana Weber must

Vargas-Maya, N. I., Hernández, G. A. G., Padilla-Guerrero, I. E., & Guzmán, J. C. T. (2016) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-016-1871-2 · Cited by 7 · see citing works

The nutrient transceptor/PKA pathway functions independently of TOR and responds to leucine and Gcn2 in a TOR-independent manner

Conrad, M., Kankipati, H. N., Kimpe, M., Zeebroeck, G. V., Zhang, Z., & Thevelein, J. M. (2017) · FEMS Yeast Research · doi:10.1093/femsyr/fox048 · Cited by 7 · see citing works

EGO complex at 20: The Rag GTPase-TORC1 nutrient-sensing blueprint.

Virgilio, C. D. (2026) · Molecules and Cells · doi:10.1016/j.molcel.2025.12.018 · Cited by 6 · see citing works

Involvement of Gtr1p in the oxidative stress response in yeast Saccharomyces cerevisiae

Sekiguchi, T., Ishii, T., Kamada, Y., Funakoshi, M., Kobayashi, H., & Furuno, N. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.02.016 · Cited by 6 · see citing works

Macronucleophagy maintains cell viability under nitrogen starvation by modulating micronucleophagy

Li, Z., Mochida, K., & Nakatogawa, H. (2024) · Nature Communications · doi:10.1038/s41467-024-55045-9 · Cited by 4 · see citing works

The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicine

Xiao, X., & Dokudovskaya, S. (2026) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2026.02.004 · Cited by 4 · see citing works

Non-dikarya fungi share the TORC1 pathway with animals, not with Saccharomyces cerevisiae

Barua, D., Płecha, M., & Muszewska, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-89635-4 · Cited by 4 · see citing works

Paralogs in the PKA Regulon Traveled Different Evolutionary Routes to Divergent Expression in Budding Yeast

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Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing

Tettoni, S. D., Egri, S. B., Doxsey, D. D., Veinotte, K., Ouch, C., Chang, J.-Y., Song, K., Chen, X., & Shen, K. (2023) · Structure · doi:10.1016/j.str.2023.06.012 · Cited by 3 · see citing works

Multilayered regulation of TORC1 signaling by Ait1, Gcn2, and SEAC/GATOR during nitrogen limitation and starvation

Padilla, C. M., Lim, J., Lipinski, A. A., Langlais, P. R., & Capaldi, A. (2025) · Nature Communications · doi:10.1038/s41467-025-66907-1 · Cited by 1 · see citing works

TOR signaling on membranes

Loewith, R., & Tafur, L. (2025) · FEBS Letters · doi:10.1002/1873-3468.70171

Ragtime Regulation: Mechanism of TORC1 Activation in Nutrient Sensing

Williams, R. L., & Anandapadamanaban, M. (2017) · Biochemistry · doi:10.1021/acs.biochem.7b01120 · Cited by 1 · see citing works

Analisis funcional de PP2AB55 en ciclo celular, autofagia y transcripcion

Bolado, A. U. V. (2020) · doi:10.14201/gredos.145212

The Yeast FKH/APC Stress and Sch9/Tor1 Nutrient Response Pathways Mutually Antagonize One Another to Determine Yeast LifespanPreprint

Postnikoff, S. D. L., Malo, M. E., & Harkness, T. A. A. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3288531

The Greatwall-Endosulfine-PP2A/B55 pathway in Schizosaccharomyces pombe: regulatory mechanisms and roles in cell differentiation and ageing

García-Blanco, N. (2021) · doi:10.14201/gredos.149314

Single-cell analysis of TORC1 and PKA signalling during the budding yeast cell cycle

Guerra, P. (2022) · doi:10.33612/diss.217083871

Biochemical characterization of mTORC1 regulation by glutamine metabolism

Bodineau, C. (2020) · theses.fr (ABES) · doi:10.70675/9d5aaabdz81bdz4118zb3edze237bdd8dee0

Sphingolipids integrate TORC2 with TORC1 through vacuolar liquid-ordered domain formationPreprint

Denda, H., Eto, K., Nishiyama, K., HAGIWARA, R., Okano, T., YOSHIZUMI, S., Hirota, A., NAKAZONO, K., Yabuki, Y., Okano, A., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.03.729730

The oxidative cost of losing low temperature viability protein 1 [Ltv1]: insights into cellular damage and homeostasis

Remines, M., Ammerman, S. A., Keeney, J. B., & Strome, E. D. (2026) · FEMS Yeast Research · doi:10.1093/femsyr/foag019

Glucose Stress Response Through the PKA-Msn2 Axis in Saccharomyces cerevisiae

Lao, Z. (2026) · doi:10.56902/etdcrp.2026.100

Ego3 Functions as a Homodimer to Mediate the Interaction between Gtr1-Gtr2 and Ego1 in the EGO Complex to Activate TORC1

Zhang, T., Gulli, M., Yang, H., VIRGILIO, C. D., & Ding, J. (2012) · Structure · doi:10.1016/j.str.2012.09.019 · Cited by 63 · see citing works

Structural insights into the EGO-TC–mediated membrane tethering of the TORC1-regulatory Rag GTPases

Zhang, T., Gulli, M., Zhang, Z., Tang, X. H., Ye, J., VIRGILIO, C. D., & Ding, J. (2019) · Science Advances · doi:10.1126/sciadv.aax8164 · Cited by 22 · see citing works

Amino acid residues required for Gtr1p‐Gtr2p complex formation and its interactions with the Ego1p‐Ego3p complex and TORC1 components in yeast

Sekiguchi, T., Kamada, Y., Furuno, N., Funakoshi, M., & Kobayashi, H. (2014) · Genes to Cells · doi:10.1111/gtc.12145 · Cited by 23 · see citing works

The Vam6 GEF Controls TORC1 by Activating the EGO Complex

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Crystal structure of the Gtr1p–Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation

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