Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

Shelterin: the protein complex that shapes and safeguards human telomeres

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T‐loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang

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Growth Retardation and Leaky SCID Phenotype of Ku70-Deficient Mice

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Ku acts in a unique way at the mammalian telomere to prevent end joiningPreprint

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Ku is associated with the telomere in mammals

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The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities

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Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells

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The Human Rap1 Protein Complex and Modulation of Telomere Length

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DNA-PKcs is critical for telomere capping

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Interaction of human Ku70 with TRF2

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Protection of Telomeres by the Ku Protein in Fission Yeast

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DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair

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Ku Binds Telomeric DNA in Vitro

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A Quantitative Assay for Telomere Protection in Saccharomyces cerevisiae

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Alternative Pathways for the Repair of RAG-Induced DNA Breaks

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An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres

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Which end: dissecting Ku's function at telomeres and double-strand breaks: Figure 1.Preprint

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How Shelterin Protects Mammalian Telomeres

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The multifaceted roles of PARP1 in DNA repair and chromatin remodelling

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Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1

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How Telomeres Solve the End-Protection Problem

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Shelterin-Mediated Telomere Protection

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Telomeres in cancer: tumour suppression and genome instability

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Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

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Removal of Shelterin Reveals the Telomere End-Protection Problem

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53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

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Targeting telomeres and telomerase

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Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth

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End-joining, translocations and cancer

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53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions

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Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4–ligase IV during chromosomal translocation formation

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MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection

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Loss of Rap1 Induces Telomere Recombination in the Absence of NHEJ or a DNA Damage Signal

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The Ku heterodimer: Function in DNA repair and beyond

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Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

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Double strand break repair functions of histone H2AX

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In Vivo Stoichiometry of Shelterin Components

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Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers

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53BP1: a DSB escortPreprint

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Roles of Werner syndrome protein in protection of genome integrity

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Apollo, an Artemis-Related Nuclease, Interacts with TRF2 and Protects Human Telomeres in S Phase

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Telomeric Strategies: Means to an End

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Characterization of Oxidative Guanine Damage and Repair in Mammalian Telomeres

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Telomere protection by mammalian Pot1 requires interaction with Tpp1

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TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signalingPreprint

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The function of classical and alternative non‐homologous end‐joining pathways in the fusion of dysfunctional telomeres

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Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells

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ATM activates p53 by regulating MDM2 oligomerization and E3 processivity

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The Role of Telomere Biology in Cancer

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Apollo Contributes to G Overhang Maintenance and Protects Leading-End Telomeres

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Mechanisms of telomere loss and their consequences for chromosome instability

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How Shelterin Solves the Telomere End-Protection ProblemPreprint

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The Telomere Deprotection Response Is Functionally Distinct from the Genomic DNA Damage Response

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Mouse Embryonic Stem Cells, but Not Somatic Cells, Predominantly Use Homologous Recombination to Repair Double-Strand DNA Breaks

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Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats

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XIAP inhibits autophagy via XIAP‐Mdm2‐p53 signalling

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The tumour suppressor RASSF1A promotes MDM2 self‐ubiquitination by disrupting the MDM2–DAXX–HAUSP complex

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The Role of Double-Strand Break Repair Pathways at Functional and Dysfunctional TelomeresPreprint

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Degradation of MDM2 by the Interaction between Berberine and DAXX Leads to Potent Apoptosis in MDM2-Overexpressing Cancer Cells

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Ku Suppresses Formation of Telomeric Circles and Alternative Telomere Lengthening in Arabidopsis

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Functional Dissection of Human and Mouse POT1 Proteins

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Telomere uncapping and alternative lengthening of telomeres

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Cell Cycle-Dependent Role of MRN at Dysfunctional Telomeres: ATM Signaling-Dependent Induction of Nonhomologous End Joining (NHEJ) in G1 and Resection-Mediated Inhibition of NHEJ in G2

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Telomere and Telomerase Biology

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Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication

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Multiple pathways inhibit NHEJ at telomeresPreprint

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