The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
MAPK signalling in cellular metabolism: stress or wellness?
Open accessAbstract
Mitogen‐activated protein kinase (MAPK) signalling occurs in response to almost any change in the extracellular or intracellular milieu that affects the metabolism of the cell, organ or the entire organism. MAPK‐dependent signal transduction is required for physiological metabolic adaptation, but inappropriate MAPK signalling contributes to the development of several interdependent pathological traits, collectively known as metabolic syndrome. Metabolic syndrome leads to life‐threatening clinical consequences, such as type 2 diabetes. This Review provides an overview of the MAPK‐signalling mechanisms that underly basic cellular metabolism, discussing their link to disease.
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Cites
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Cited by
Inflammation, metaflammation and immunometabolic disorders
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Biochemical and cellular properties of insulin receptor signalling
Haeusler, R. A., McGraw, T. E., & Accili, D. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.89 · Cited by 739
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Metadata
- Authors
- Gehart, H., Kumpf, S., Ittner, A., & Ricci, R.
- Venue
- EMBO reports
- Published
- 2010-10-08
- Volume
- 11
- Issue
- 11
- Pages
- 834-840
- ISSN
- 1469-221X (ISSN-L)
- 1469-3178
- OpenAlex
- W2037023961
- Cited by
- 326
- References
- 54
- FWCI
- 5.91
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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