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Cited by 329

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

The dynamics of gut‐associated microbial communities during inflammation

Open access
Winter, Sebastian E, Lopez, Christopher A, Bäumler, Andreas J·2013·EMBO reports

Abstract

Our intestine is host to a large microbial community (microbiota) that educates the immune system and confers niche protection. Profiling of the gut‐associated microbial community reveals a dominance of obligate anaerobic bacteria in healthy individuals. However, intestinal inflammation is associated with a disturbance of the microbiota—known as dysbiosis—that often includes an increased prevalence of facultative anaerobic bacteria. This group contains potentially harmful bacterial species, the bloom of which can further exacerbate inflammation. Here, we review the mechanisms that generate changes in the microbial community structure during inflammation. One emerging concept is that electron acceptors generated as by‐products of the host inflammatory response feed facultative anaerobic bacteria selectively, thereby increasing their prevalence within the community. This new paradigm has broad implications for understanding dysbiosis during gut inflammation and identifies potential targets for intervention strategies.

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Metadata

Authors
Winter, S. E., Lopez, C. A., & Bäumler, A. J.
Venue
EMBO reports
Published
2013-03-12
Volume
14
Issue
4
Pages
319-327
ISSN
  • 1469-221X (ISSN-L)
  • 1469-3178
OpenAlex
W2164175488
Cited by
329
References
17
FWCI
11.83
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The dynamics of gut‐associated microbial communities during inflammation. https://app.cochat.ai/papers/10.1038/embor.2013.27
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Winter, S. E., Lopez, C. A., & Bäumler, A. J. (2013). The dynamics of gut‐associated microbial communities during inflammation. EMBO reports. https://doi.org/10.1038/embor.2013.27

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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