Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442 · see citing works

Diversity of the Human Intestinal Microbial Flora

Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913 · see citing works

Linking long-term dietary patterns with gut microbial enterotypes

Wu, G. D., Chen, J., Hoffmann, C., Bittinger, K., Chen, Y.-Y., Keilbaugh, S. A., Bewtra, M., Knights, D., Walters, W. A., Knight, R., et al. (2011) · Science · doi:10.1126/science.1208344 · Cited by 6,513 · see citing works

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591 · see citing works

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549 · see citing works

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T _reg Cell Homeostasis

Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M., Glickman, J. N., & Garrett, W. S. (2013) · Science · doi:10.1126/science.1241165 · Cited by 5,413 · see citing works

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H., et al. (2001) · Nature · doi:10.1038/35079114 · Cited by 5,030 · see citing works

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

Arpaia, N., Campbell, C., Fan, X., Dikiy, S., van der Veeken, J., deRoos, P., Liu, H., Cross, J. R., Pfeffer, K., Coffer, P. J., et al. (2013) · Nature · doi:10.1038/nature12726 · Cited by 4,838 · see citing works

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

Frank, D. N., St. Amand, A. L., Feldman, R. A., Boedeker, E. C., Harpaz, N., & Pace, N. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706625104 · Cited by 4,611 · see citing works

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.033 · Cited by 4,554 · see citing works

<i>Faecalibacterium prausnitzii</i> is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804812105 · Cited by 4,413 · see citing works

Interleukin-10-deficient mice develop chronic enterocolitis

Kühn, R., Löhler, J., Rennick, D. M., Rajewsky, K., & Müller, W. (1993) · Cell · doi:10.1016/0092-8674(93)80068-p · Cited by 4,248 · see citing works

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

Gevers, D., Kugathasan, S., Denson, L. A., Vázquez-Baeza, Y., Van Treuren, W., Ren, B., Schwager, E., Knights, D., Song, S. J., Yassour, M., et al. (2014) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2014.02.005 · Cited by 3,220 · see citing works

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

Turnbaugh, P. J., Ridaura, V. K., Faith, J. J., Rey, F. E., Knight, R., & Gordon, J. I. (2009) · Science Translational Medicine · doi:10.1126/scitranslmed.3000322 · Cited by 3,058 · see citing works

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

Atarashi, K., Tanoue, T., Oshima, K., Suda, W., Nagano, Y., Nishikawa, H., Fukuda, S., Saito, T., Narushima, S., Hase, K., et al. (2013) · Nature · doi:10.1038/nature12331 · Cited by 2,872 · see citing works

Bile salt biotransformations by human intestinal bacteria

Ridlon, J. M., Kang, D.-J., & Hylemon, P. B. (2006) · Journal of Lipid Research · doi:10.1194/jlr.r500013-jlr200 · Cited by 2,829 · see citing works

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

Desai, M. S., Seekatz, A. M., Koropatkin, N. M., Kamada, N., Hickey, C. A., Wolter, M., Pudlo, N. A., Kitamoto, S., Terrapon, N., Muller, A., et al. (2016) · Cell · doi:10.1016/j.cell.2016.10.043 · Cited by 2,805 · see citing works

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

Morgan, X. C., Tickle, T. L., Sokol, H., Gevers, D., Devaney, K. L., Ward, D. V., Reyes, J. A., Shah, S. A., LeLeiko, N., Snapper, S. B., et al. (2012) · Genome Biology · doi:10.1186/gb-2012-13-9-r79 · Cited by 2,713 · see citing works

A microbial symbiosis factor prevents intestinal inflammatory disease

Mazmanian, S. K., Round, J. L., & Kasper, D. L. (2008) · Nature · doi:10.1038/nature07008 · Cited by 2,340 · see citing works

Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach

Manichanh, C., Rigottier-Gois, L., Bonnaud, E., Gloux, K., Pelletier, E., Frangeul, L., Nalin, R., Jarrin, C., Chardon, P., Marteau, P., et al. (2006) · Gut · doi:10.1136/gut.2005.073817 · Cited by 2,277 · see citing works

Intestinal inflammation targets cancer-inducing activity of the microbiota

Arthur, J. C., Perez-Chanona, E., Mühlbauer, M., Tomkovich, S., Uronis, J. M., Fan, T.-J., Campbell, B. J., Abujamel, T., Dogan, B., Rogers, A. B., et al. (2012) · Science · doi:10.1126/science.1224820 · Cited by 2,263 · see citing works

Role of the gut microbiota in immunity and inflammatory disease

Kamada, N., Seo, S.-U., Chen, G. Y., & Núñez, G. (2013) · Nature reviews. Immunology · doi:10.1038/nri3430 · Cited by 2,256 · see citing works

Inducible Foxp3 ⁺ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

Round, J. L., & Mazmanian, S. K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909122107 · Cited by 2,233 · see citing works

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

Johansson, M. E. V., Phillipson, M., Petersson, J., Velcich, A., Holm, L., & Hansson, G. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803124105 · Cited by 2,200 · see citing works

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

Viaud, S., Saccheri, F., Mignot, G., Yamazaki, T., Daillère, R., Hannani, D., Enot, D. P., Pfirschke, C., Engblom, C., Pittet, M. J., et al. (2013) · Science · doi:10.1126/science.1240537 · Cited by 2,050 · see citing works

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

Buffie, C. G., Bucci, V., Stein, R. R., McKenney, P. T., Ling, L., Gobourne, A., No, D., Liu, H., Kinnebrew, M., Viale, A., et al. (2015) · Nature · doi:10.1038/nature13828 · Cited by 1,872 · see citing works

Ecology of prokaryotic viruses

Weinbauer, M. G. (2003) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2003.08.001 · Cited by 1,775 · see citing works

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

Ivanov, I. I., Frutos, R. D. L., Manel, N., Yoshinaga, K., Rifkin, D. B., Sartor, R. B., Finlay, B. B., & Littman, D. R. (2008) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2008.09.009 · Cited by 1,770 · see citing works

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

Rioux, J. D., Xavier, R. J., Taylor, K. D., Silverberg, M. S., Goyette, P., Huett, A., Green, T., Kuballa, P., Barmada, M. M., Datta, L. W., et al. (2007) · Nature Genetics · doi:10.1038/ng2032 · Cited by 1,769 · see citing works

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

Ouyang, W., Kolls, J. K., & Zheng, Y. (2008) · Immunity · doi:10.1016/j.immuni.2008.03.004 · Cited by 1,697 · see citing works

Muc2-Deficient Mice Spontaneously Develop Colitis, Indicating That MUC2 Is Critical for Colonic Protection

Van der Sluis, M., De Koning, B. A. E., De Bruijn, A. C. J. M., Velcich, A., Meijerink, J. P. P., Van Goudoever, J. B., Büller, H. A., Dekker, J., Van Seuningen, I., Renes, I. B., et al. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.04.020 · Cited by 1,684 · see citing works

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

Walker, A. W., Ince, J., Duncan, S. H., Webster, L. M., Holtrop, G., Ze, X., Brown, D., Stares, M. D., Scott, P., Bergerat, A., et al. (2011) · The ISME Journal · doi:10.1038/ismej.2010.118 · Cited by 1,632 · see citing works

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

Round, J. L., Lee, S. M., Li, J., Tran, G., Jabri, B., Chatila, T. A., & Mazmanian, S. K. (2011) · Science · doi:10.1126/science.1206095 · Cited by 1,604 · see citing works

Bacteriophage Therapy

Sulakvelidze, A., Alavidze, Z., & Morris, J. G. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.3.649-659.2001 · Cited by 1,569 · see citing works

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

Darfeuille-Michaud, A., Boudeau, J., Bulois, P., Neut, C., Glasser, A.-L., Barnich, N., Bringer, M.-A., Swidsinski, A., Beaugerie, L., & Colombel, J.-F. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.04.061 · Cited by 1,566 · see citing works

Resident Enteric Bacteria Are Necessary for Development of Spontaneous Colitis and Immune System Activation in Interleukin-10-Deficient Mice

Sellon, R. K., Tonkonogy, S., Schultz, M., Dieleman, L. A., Grenther, W., Balish, E., Rennick, D. M., & Sartor, R. B. (1998) · Infection and Immunity · doi:10.1128/iai.66.11.5224-5231.1998 · Cited by 1,483 · see citing works

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

Gaboriau-Routhiau, V., Rakotobe, S., Lécuyer, E., Mulder, I., Lan, A., Bridonneau, C., Rochet, V., Pisi, A., De Paepe, M., Brandi, G., et al. (2009) · Immunity · doi:10.1016/j.immuni.2009.08.020 · Cited by 1,452 · see citing works

How glycan metabolism shapes the human gut microbiota

Koropatkin, N. M., Cameron, E. A., & Martens, E. C. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2746 · Cited by 1,419 · see citing works

The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine

Vaishnava, S., Yamamoto, M., Severson, K. M., Ruhn, K. A., Yu, X., Koren, O., Ley, R., Wakeland, E. K., & Hooper, L. V. (2011) · Science · doi:10.1126/science.1209791 · Cited by 1,412 · see citing works

Mucosal flora in inflammatory bowel disease

Swidsinski, A. V., Ladhoff, A., Pernthaler, A., Swidsinski, S., Loening-Baucke, V. A., Ortner, M., Weber, J., Hoffmann, U., Schreiber, S., Dietel, M., et al. (2002) · Gastroenterology · doi:10.1053/gast.2002.30294 · Cited by 1,344 · see citing works

Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae

Lupp, C., Robertson, M. L., Wickham, M. E., Sekirov, I., Champion, O. L., Gaynor, E. C., & Finlay, B. B. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.06.010 · Cited by 1,310 · see citing works

Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease

Palm, N. W., de Zoete, M. R., Cullen, T. W., Barry, N. A., Stefanowski, J., Hao, L., Degnan, P. H., Hu, J., Peter, I., Zhang, W., et al. (2014) · Cell · doi:10.1016/j.cell.2014.08.006 · Cited by 1,286 · see citing works

Gut inflammation provides a respiratory electron acceptor for Salmonella

Winter, S., Thiennimitr, P., Winter, M. G., Butler, B. P., Huseby, D. L., Crawford, R. W., Russell, J. M., Bevins, C. L., Adams, L. G., Tsolis, R. M., et al. (2010) · Nature · doi:10.1038/nature09415 · Cited by 1,271 · see citing works

Viruses in the faecal microbiota of monozygotic twins and their mothers

Reyes, A., Haynes, M. R., Hanson, N., Angly, F. E., Heath, A. C., Rohwer, F. L., & Gordon, J. I. (2010) · Nature · doi:10.1038/nature09199 · Cited by 1,198 · see citing works

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

Bain, C. C., Bravo-Blas, A., Scott, C. L., Gomez Perdiguero, E., Geissmann, F., Henri, S., Malissen, B., Osborne, L. C., Artis, D., & Mowat, A. M. (2014) · Nature Immunology · doi:10.1038/ni.2967 · Cited by 1,178 · see citing works

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

Inagaki, T., Moschetta, A., Lee, Y.-K., Peng, L., Zhao, G., Downes, M., Yu, R. T., Shelton, J. M., Richardson, J. A., Repa, J. J., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509592103 · Cited by 1,164 · see citing works

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats.

Taurog, J. D., Richardson, J. A., Croft, J. T., Simmons, W. A., Zhou, M., FERNÁNDEZ-SUEIRO, J. L., Balish, E., & Hammer, R. E. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.6.2359 · Cited by 1,156 · see citing works

IgE in allergy and asthma today

Gould, H. J., & Sutton, B. J. (2008) · Nature reviews. Immunology · doi:10.1038/nri2273 · Cited by 1,138 · see citing works

A Primitive T Cell-Independent Mechanism of Intestinal Mucosal IgA Responses to Commensal Bacteria

Macpherson, A. J., Gatto, D., Sainsbury, E., Harriman, G. R., Hengartner, H., & Zinkernagel, R. M. (2000) · Science · doi:10.1126/science.288.5474.2222 · Cited by 1,113 · see citing works

Th17 cell induction by adhesion of microbes to intestinal epithelial cells

Atarashi, K., Tanoue, T., Ando, M., Kamada, N., Nagano, Y., Narushima, S., Suda, W., Imaoka, A., Setoyama, H., Nagamori, T., et al. (2015) · Cell · doi:10.1016/j.cell.2015.08.058 · Cited by 1,071 · see citing works

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

Stecher, B., Robbiani, R., Walker, A. W., Westendorf, A. M., Barthel, M., Kremer, M., Chaffron, S., Macpherson, A. J., Buer, J., Parkhill, J., et al. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050244 · Cited by 1,048 · see citing works

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

Ng, K. M., Ferreyra, J. A., Higginbottom, S. K., Lynch, J. B., Kashyap, P. C., Gopinath, S., Naidu, N., Choudhury, B., Weimer, B. C., Monack, D. M., et al. (2013) · Nature · doi:10.1038/nature12503 · Cited by 1,035 · see citing works

Colicin Biology

Cascalès, E., Buchanan, S. K., Duché, D., Kleanthous, C., Lloubès, R., Postle, K., Riley, M. A., Slatin, S. L., & Cavard, D. (2007) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00036-06 · Cited by 1,023 · see citing works

Host-Derived Nitrate Boosts Growth of <i>E. coli</i> in the Inflamed Gut

Winter, S. E., Winter, M. G., Xavier, M. N., Thiennimitr, P., Poon, V., Keestra, A. M., Laughlin, R. C., Gomez, G., Wu, J., Lawhon, S. D., et al. (2013) · Science · doi:10.1126/science.1232467 · Cited by 1,019 · see citing works

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

Theriot, C. M., Koenigsknecht, M. J., Carlson, P. E., Hatton, G. E., Nelson, A. M., Li, B., Huffnagle, G. B., Z. Li, J., & Young, V. B. (2014) · Nature Communications · doi:10.1038/ncomms4114 · Cited by 974 · see citing works

Colorectal Cancer in Mice Genetically Deficient in the Mucin Muc2

Velcich, A., Yang, W., Heyer, J., Fragale, A., Nicholas, C., Viani, S., Kucherlapati, R., Lipkin, M., Yang, K., & Augenlicht, L. (2002) · Science · doi:10.1126/science.1069094 · Cited by 936 · see citing works

The human gut virome: inter-individual variation and dynamic response to diet

Minot, S., Sinha, R., Chen, J., Li, H., Keilbaugh, S. A., Wu, G. D., Lewis, J. D., & Bushman, F. D. (2011) · Genome Research · doi:10.1101/gr.122705.111 · Cited by 935 · see citing works

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

Smythies, L. E., Sellers, M. T., Clements, R. H., Mosteller‐Barnum, M., Meng, G., Benjamin, W. H., Orenstein, J. M., & Smith, P. D. (2005) · Journal of Clinical Investigation · doi:10.1172/jci200519229 · Cited by 924 · see citing works

Communicable Ulcerative Colitis Induced by T-bet Deficiency in the Innate Immune System

Garrett, W. S., Lord, G. M., Punit, S., Lugo‐Villarino, G., Mazmanian, S. K., Ito, S., Glickman, J. N., & Glimcher, L. H. (2007) · Cell · doi:10.1016/j.cell.2007.08.017 · Cited by 918 · see citing works

Early life antibiotic‐driven changes in microbiota enhance susceptibility to allergic asthma

Russell, S. L., Gold, M. J., Hartmann, M., Willing, B. P., Thorson, L., Wlodarska, M., Gill, N., Blanchet, M., Mohn, W. W., McNagny, K. M., et al. (2012) · The EMBO Reports · doi:10.1038/embor.2012.32 · Cited by 883 · see citing works

Mechanisms of inflammation-driven bacterial dysbiosis in the gut

Zeng, M. Y., Inohara, N., & Núñez, G. (2016) · Mucosal Immunology · doi:10.1038/mi.2016.75 · Cited by 872 · see citing works

Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum

D’Haens, G., Geboes, K., Peeters, M., Baert, F., PENNINCKX, F. M., & Rutgeerts, P. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70476-7 · Cited by 866 · see citing works

Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella

Rivera-Chávez, F., Zhang, L. F., Faber, F., Lopez, C. A., Byndloss, M. X., Olsan, E. E., Xu, G., Velazquez, E. M., Lebrilla, C. B., Winter, S. E., et al. (2016) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2016.03.004 · Cited by 864 · see citing works

Bacteriocin production as a mechanism for the antiinfective activity of <i>Lactobacillus salivarius</i> UCC118

Corr, S. C., Li, Y., Riedel, C. U., O'Toole, P. W., Hill, C., & Gahan, C. G. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700440104 · Cited by 853 · see citing works

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

Qiu, J., Heller, J. J., Guo, X.-H., Chen, Z.-M. E., Fish, K., Fu, Y.-X., & Zhou, L. (2011) · Immunity · doi:10.1016/j.immuni.2011.11.011 · Cited by 850 · see citing works

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

Geuking, M. B., Cahenzli, J., Lawson, M. A. E., Ng, D. C. K., Slack, E., Hapfelmeier, S., McCoy, K. D., & Macpherson, A. J. (2011) · Immunity · doi:10.1016/j.immuni.2011.03.021 · Cited by 840 · see citing works

Neutrophil ageing is regulated by the microbiome

Zhang, D., Chen, G., Manwani, D., Mortha, A., Xu, C., Faith, J. J., Burk, R. D., Kunisaki, Y., Jang, J.-E., Scheiermann, C., et al. (2015) · Nature · doi:10.1038/nature15367 · Cited by 839 · see citing works

NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease

Caruso, R., Warner, N., Inohara, N., & Núñez, G. (2014) · Immunity · doi:10.1016/j.immuni.2014.12.010 · Cited by 830 · see citing works

Metagenomic Analyses of an Uncultured Viral Community from Human Feces

Breitbart, M., Hewson, I., Felts, B., Mahaffy, J. M., Nulton, J., Salamon, P., & Rohwer, F. L. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.20.6220-6223.2003 · Cited by 828 · see citing works

Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease

Greenblum, S., Turnbaugh, P. J., & Borenstein, E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1116053109 · Cited by 821 · see citing works

Bacterial flagellin is a dominant antigen in Crohn disease

Lodes, M. J., Cong, Y., Elson, C. O., Mohamath, R., Landers, C. J., Targan, S. R., Fort, M., & Hershberg, R. M. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420295 · Cited by 802 · see citing works

Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles

Kiss, E. A., Vonarbourg, C., Kopfmann, S., Hobeika, E., Finke, D., Esser, C., & Diefenbach, A. (2011) · Science · doi:10.1126/science.1214914 · Cited by 801 · see citing works

The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts

Skaar, E. P. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000949 · Cited by 796 · see citing works

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

Garrett, W. S., Gallini, C. A., Yatsunenko, T., Michaud, M., DuBois, A., Delaney, M. L., Punit, S., Karlsson, M., Bry, L., Glickman, J. N., et al. (2010) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2010.08.004 · Cited by 788 · see citing works

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

Lee, J. S., Cella, M., McDonald, K. G., Garlanda, C., Kennedy, G. D., Nukaya, M., Mantovani, A., Kopan, R., Bradfield, C. A., Newberry, R. D., et al. (2012) · Nature Immunology · doi:10.1038/ni.2187 · Cited by 777 · see citing works

Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum

Rutgeerts, P., Peeters, M., Hiele, M. I., Vantrappen, G. R., Pennincx, F., Aerts, R., Kerremans, R., & Goboes, K. (1991) · The Lancet · doi:10.1016/0140-6736(91)90663-a · Cited by 758 · see citing works

Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon

Seksik, P., Rigottier‐Gois, L., Gramet, G., BRIEND‐SUTREN, M., Pochart, P., Marteau, P. R., Jian, R., & Dore, J. M. (2003) · Gut · doi:10.1136/gut.52.2.237 · Cited by 746 · see citing works

Specificity of Polysaccharide Use in Intestinal Bacteroides Species Determines Diet-Induced Microbiota Alterations

Sonnenburg, E. D., Zheng, H., Joglekar, P., Higginbottom, S. K., Firbank, S. J., Bolam, D. N., & Sonnenburg, J. L. (2010) · Cell · doi:10.1016/j.cell.2010.05.005 · Cited by 745 · see citing works

Alternative respiratory pathways of Escherichia coli: energetics and transcriptional regulation in response to electron acceptors

Unden, G., & Bongaerts, J. (1997) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(97)00034-0 · Cited by 744 · see citing works

Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria

Sonnenberg, G. F., Monticelli, L. A., Alenghat, T., Fung, T. C., Hutnick, N. A., Kunisawa, J., Shibata, N., Grunberg, S., Sinha, R., Zahm, A. M., et al. (2012) · Science · doi:10.1126/science.1222551 · Cited by 738 · see citing works

Enhanced Escherichia coli adherence and invasion in Crohn’s disease and colon cancer 1 1The authors thank Professor T. K. Korhonen (Division of General Microbiology, University of Helsinki, Finland), who kindly donated Escherichia coli IH11165; Professor J.-F. Colombel (Laboratoire de Recherche sur les Maladies Inflammatoire de l’Intestine, Centre Hospitalier Universitaire, Lille, France) and Professor A. Darfeuille-Michaud (Faculte de Pharmacie, Clermont-Ferrand, France), who kindly donated the Crohn’s disease ileal isolates LF10 and LF82; and Dr. Keith Leiper (Gastroenterology Unit, Royal Liverpool & Broadgreen University Hospitals Trust, Liverpool, UK) for his cooperation in obtaining colorectal tissue specimens.As a consequence of the work described herein, a patent application has been filed by the University of Liverpool regarding the use of soluble plantain fiber in Crohn’s disease.

Martin, H., Campbell, B. J., Hart, C. A., Mpofu, C., Nayar, M. K., Singh, R., Englyst, H. N., Williams, H. F., & Rhodes, J. M. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.03.054 · Cited by 719 · see citing works

Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis

Pammi, M., Cope, J., Tarr, P. I., Warner, B. B., Morrow, A. L., Mai, V., Gregory, K. E., Kroll, J. S., McMurtry, V., Ferris, M. J., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0248-8 · Cited by 708 · see citing works

Regulated virulence controls the ability of a pathogen to compete with the gut microbiota

Kamada, N., Kim, Y.-G., Sham, H. P., Vallance, B. A., Puente, J. L., Martens, E. C., & Núñez, G. (2012) · Science · doi:10.1126/science.1222195 · Cited by 682 · see citing works

Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome

Saulnier, D. M., Riehle, K., Mistretta, T., Diaz, M., Mandal, D., Raza, S., Weidler, E. M., Qin, X., Coarfa, C., Milosavljevic, A., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.06.072 · Cited by 672 · see citing works

Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis

Karhausen, J., Furuta, G. T., Tomaszewski, J. E., Johnson, R. S., Colgan, S. P., & Haase, V. H. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200421086 · Cited by 655 · see citing works

Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection

Khosravi, A., Yáñez, A., Price, J. G., Chow, A. T., Mérad, M., Goodridge, H. S., & Mazmanian, S. K. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.02.006 · Cited by 651 · see citing works

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

Chu, H., Khosravi, A., Kusumawardhani, I. P., Kwon, A. H. K., Vasconcelos, A. C., Cunha, L. D., Mayer, A. E., Shen, Y., Wu, W.-L., Kambal, A., et al. (2016) · Science · doi:10.1126/science.aad9948 · Cited by 647 · see citing works

Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum

Baumgart, M., Dogan, B., Rishniw, M., Weitzman, G., Bosworth, B. P., Yantiss, R. K., Orsi, R. H., Wiedmann, M., McDonough, P. L., Kim, S. G., et al. (2007) · The ISME Journal · doi:10.1038/ismej.2007.52 · Cited by 630 · see citing works

Bacterial colonization factors control specificity and stability of the gut microbiota

Lee, S. M., Donaldson, G. P., Mikulski, Z., Boyajian, S., Ley, K. F., & Mazmanian, S. K. (2013) · Nature · doi:10.1038/nature12447 · Cited by 629 · see citing works

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

Bergstrom, K. S. B., Kissoon-Singh, V., Gibson, D. L., Ma, C., Montero, M., Sham, H. P., Ryz, N., Huang, T., Velcich, A., Finlay, B. B., et al. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000902 · Cited by 625 · see citing works

Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels

Cahenzli, J., Köller, Y., Wyss, M., Geuking, M. B., & McCoy, K. D. (2013) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2013.10.004 · Cited by 611 · see citing works

Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis

Buffie, C. G., Jarchum, I., Equinda, M., Lipuma, L., Gobourne, A., Viale, A., Ubeda, C., Xavier, J., & Pamer, E. G. (2012) · Infection and Immunity · doi:10.1128/iai.05496-11 · Cited by 596 · cited 1× · see citing works

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

Barnich, N., Carvalho, F. A., Glasser, A.-L., Darcha, C., Jantscheff, P., Allez, M., Peeters, H., Bommelaer, G., Desreumaux, P., Colombel, J., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci30504 · Cited by 590 · see citing works

Selective IgA Deficiency

Yel, L. (2010) · Journal of Clinical Immunology · doi:10.1007/s10875-009-9357-x · Cited by 582 · see citing works

The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice

Deshmukh, H. S., Liu, Y., Menkiti, O. R., Mei, J., Dai, N., O'Leary, C. E., Oliver, P. M., Kolls, J. K., Weiser, J. N., & Worthen, G. S. (2014) · Nature Medicine · doi:10.1038/nm.3542 · Cited by 579 · see citing works

Consumption of human milk oligosaccharides by gut-related microbes

Marcobal, A., Barboza, M., Froehlich, J. W., Block, D. E., German, J. B., Lebrilla, C. B., & Mills, D. A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9044205 · Cited by 568 · see citing works

Innate lymphoid cells regulate intestinal epithelial cell glycosylation

Goto, Y., Obata, T., Kunisawa, J., Sato, S., Ivanov, I. I., Lamichhane, A., Takeyama, N., Kamioka, M., Sakamoto, M., Matsuki, T., et al. (2014) · Science · doi:10.1126/science.1254009 · Cited by 568 · see citing works

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

Brest, P., Lapaquette, P., Souidi, M., Lebrigand, K., Cesaro, A., Vouret-Craviari, V., Mari, B., Barbry, P., Mosnier, J.-F., Hébuterne, X., et al. (2011) · Nature Genetics · doi:10.1038/ng.762 · Cited by 563 · see citing works

Antibiotic-mediated antagonism leads to a bacterial game of rock–paper–scissors in vivo

Kirkup, B. C., & Riley, M. A. (2004) · Nature Cell Biology · doi:10.1038/nature02429 · Cited by 561 · see citing works

Probiotic Bacteria Reduce Salmonella Typhimurium Intestinal Colonization by Competing for Iron

Deriu, E., Liu, J. Z., Pezeshki, M., Edwards, R. A., Ochoa, R. J., Contreras, H., Libby, S. J., Fang, F. C., & Raffatellu, M. (2013) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2013.06.007 · Cited by 550 · see citing works

Normalization of host intestinal mucus layers requires long-term microbial colonization

Johansson, M. E. V., Jakobsson, H. E., Holmén-Larsson, J., Schütte, A., Ermund, A., Rodríguez-Piñeiro, A. M., Arike, L., Wising, C., Svensson, F., Bäckhed, F., et al. (2015) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2015.10.007 · Cited by 549 · see citing works

Microcins mediate competition among Enterobacteriaceae in the inflamed gut

Sassone-Corsi, M., Nuccio, S.-P., Liu, H., Hernandez, D., Vu, C. T., Takahashi, A. A., Edwards, R. A., & Raffatellu, M. (2016) · Nature · doi:10.1038/nature20557 · Cited by 549 · see citing works

Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice

Carvalho, F. A., Koren, O., Goodrich, J. K., Johansson, M. E. V., Nalbantoglu, I., Aitken, J. D., Su, Y., Chassaing, B., Walters, W. A., González, A., et al. (2012) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2012.07.004 · Cited by 548 · see citing works

Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes

Brandtzaeg, P., Halstensen, T. S., Kett, K., Krajči, P., Kvale, D., Rognum, T. O., Scott, H., & Sollid, L. M. (1989) · Gastroenterology · doi:10.1016/0016-5085(89)90406-x · Cited by 547 · see citing works

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

Sano, T., Huang, W., Hall, J. A., Yang, Y., Chen, A., Gavzy, S. J., Lee, J.-Y., Ziel, J. W., Miraldi, E. R., Domingos, A. I., et al. (2015) · Cell · doi:10.1016/j.cell.2015.08.061 · Cited by 547 · see citing works

Differences between Tissue-Associated Intestinal Microfloras of Patients with Crohn's Disease and Ulcerative Colitis

Gophna, U., Sommerfeld, K., Gophna, S., Doolittle, W., & van Zanten, S. V. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.01004-06 · Cited by 541 · see citing works

Healthy human gut phageome

Manrique, P., Bolduc, B., Walk, S. T., John van der, O. O. S. T., de Vos, W. M., & Young, M. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1601060113 · Cited by 538 · see citing works

Predicting a Human Gut Microbiota’s Response to Diet in Gnotobiotic Mice

Faith, J. J., McNulty, N. P., Rey, F. E., & Gordon, J. I. (2011) · Science · doi:10.1126/science.1206025 · Cited by 536 · see citing works

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

Pickard, J. M., Maurice, C. F., Kinnebrew, M. A., Abt, M. C., Schenten, D., Golovkina, T. V., Bogatyrev, S. R., Ismagilov, R. F., Pamer, E. G., Turnbaugh, P. J., et al. (2014) · Nature · doi:10.1038/nature13823 · Cited by 535 · see citing works

Association of antibody responses to microbial antigens and complications of small bowel Crohn’s disease

Mow, W. S., Vasiliauskas, E. A., Lin, Y.-C., Fleshner, P. R., Papadakis, K. A., Taylor, K. D., Landers, C. J., Abreu-Martin, M. T., Rotter, J. I., Yang, H., et al. (2004) · Gastroenterology · doi:10.1053/j.gastro.2003.11.015 · Cited by 517 · see citing works

Stable Engraftment of Bifidobacterium longum AH1206 in the Human Gut Depends on Individualized Features of the Resident Microbiome

Maldonado-Gómez, M. X., Martínez, I., Bottacini, F., O’Callaghan, A., Ventura, M., van Sinderen, D., Hillmann, B., Vangay, P., Knights, D., Hutkins, R. W., et al. (2016) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2016.09.001 · Cited by 517 · see citing works

Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4 + T cells

Hepworth, M. R., Fung, T. C., Masur, S. H., Kelsen, J. R., McConnell, F. M., Dubrot, J., Withers, D. R., Hugues, S., Farrar, M. A., Reith, W., et al. (2015) · Science · doi:10.1126/science.aaa4812 · Cited by 515 · see citing works

Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses

Hirota, K., Turner, J.-E., Villa, M., Duarte, J. H., Demengeot, J., Steinmetz, O. M., & Stockinger, B. (2013) · Nature Immunology · doi:10.1038/ni.2552 · Cited by 509 · see citing works

Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases

Peterson, D. A., Frank, D. N., Pace, N. R., & Gordon, J. I. (2008) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2008.05.001 · Cited by 503 · see citing works

A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem

Hooper, L. V., Xu, J., Falk, P. G., Midtvedt, T., & Gordon, J. I. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.17.9833 · Cited by 500 · see citing works

Fucose sensing regulates bacterial intestinal colonization

Pacheco, A. R., Curtis, M. M., Ritchie, J. M., Munera, D., Waldor, M. K., Moreira, C. G., & Sperandio, V. (2012) · Nature · doi:10.1038/nature11623 · Cited by 499 · see citing works

Eating For Two: How Metabolism Establishes Interspecies Interactions in the Gut

Fischbach, M. A., & Sonnenburg, J. L. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.10.002 · Cited by 494 · see citing works

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells

Lotz, M., Gütle, D., Walther, S., Ménard, S., Bogdan, C., & Hornef, M. W. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20050625 · Cited by 464 · see citing works

Bacteriocin production augments niche competition by enterococci in the mammalian gastrointestinal tract

Kommineni, S., Bretl, D. J., Lam, V., Chakraborty, R., Hayward, M., Simpson, P., Cao, Y., Bousounis, P., Kristich, C. J., & Salzman, N. H. (2015) · Nature · doi:10.1038/nature15524 · Cited by 458 · see citing works

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence

Schaubeck, M., Clavel, T., Calasan, J., Lagkouvardos, I., Haange, S. B., Jehmlich, N., Basic, M., Dupont, A., Hornef, M., Bergen, M. V., et al. (2016) · Gut · doi:10.1136/gutjnl-2015-309333 · Cited by 447 · see citing works

Requirement for Lymphoid Tissue-Inducer Cells in Isolated Follicle Formation and T Cell-Independent Immunoglobulin A Generation in the Gut

Tsuji, M., Suzuki, K., Kitamura, H., Maruya, M., Kinoshita, K., Ivanov, I. I., Itoh, K., Littman, D. R., & Fagarasan, S. (2008) · Immunity · doi:10.1016/j.immuni.2008.05.014 · Cited by 441 · see citing works

Intestinal short‐chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirA

Lawhon, S. D., Maurer, R., Suyemoto, M. M., & Altier, C. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03268.x · Cited by 440 · see citing works

Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

Herbst, T., Sichelstiel, A., Schär, C., Yadava, K., Bürki, K., Cahenzli, J., McCoy, K., Marsland, B. J., & Harris, N. L. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201010-1574oc · Cited by 440 · see citing works

Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria.

Macpherson, A. J., Khoo, U. Y., Forgács, I., Philpott‐Howard, J., & Bjarnason, I. (1996) · Gut · doi:10.1136/gut.38.3.365 · Cited by 435 · see citing works

Enteric Salmonellosis Disrupts the Microbial Ecology of the Murine Gastrointestinal Tract

Barman, M., Unold, D., Shifley, K., Amir, E., Hung, K.-C., Bos, N. A., & Salzman, N. H. (2007) · Infection and Immunity · doi:10.1128/iai.01432-07 · Cited by 428 · see citing works

Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus

Kehl-Fie, T. E., Chitayat, S., Hood, M. I., Damo, S., Restrepo, N., Garcia, C., Munro, K. A., Chazin, W. J., & Skaar, E. P. (2011) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2011.07.004 · Cited by 419 · see citing works

Absence of Epithelial Immunoglobulin a Transport, with Increased Mucosal Leakiness, in Polymeric Immunoglobulin Receptor/Secretory Component–Deficient Mice

Johansen, F., Pekna, M., Norderhaug, I. N., Haneberg, B., Hietala, M. A., Krajči, P., Betsholtz, C., & Brandtzæg, P. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.7.915 · Cited by 417 · see citing works

Gut Microbiota-Induced Immunoglobulin G Controls Systemic Infection by Symbiotic Bacteria and Pathogens

Zeng, M. Y., Cisalpino, D., Varadarajan, S., Hellman, J., Warren, H. S., Cascalho, M., Inohara, N., & Núñez, G. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.006 · Cited by 417 · see citing works

Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gut mucosal immune system

Talham, G. L., Jiang, H.-Q., Bos, N. A., & Cebra, J. J. (1999) · Infection and Immunity · doi:10.1128/iai.67.4.1992-2000.1999 · Cited by 408 · see citing works

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

Franchi, L., Kamada, N., Nakamura, Y., Burberry, A., Kuffa, P., Suzuki, S., Shaw, M. H., Kim, Y., & Núñez, G. (2012) · Nature Immunology · doi:10.1038/ni.2263 · Cited by 394 · see citing works

Gut Microbiota-Produced Succinate Promotes C. difficile Infection after Antibiotic Treatment or Motility Disturbance

Ferreyra, J. A., Wu, K. J., Hryckowian, A. J., Bouley, D. M., Weimer, B. C., & Sonnenburg, J. L. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.11.003 · Cited by 382 · see citing works

Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to Exacerbated <i>Citrobacter rodentium</i> -Induced Colitis

Wlodarska, M., Willing, B., Keeney, K. M., Menendez, A., Bergstrom, K. S., Gill, N., Russell, S. L., Vallance, B. A., & Finlay, B. B. (2011) · Infection and Immunity · doi:10.1128/iai.01104-10 · Cited by 382 · see citing works

Butyrate Specifically Down-Regulates Salmonella Pathogenicity Island 1 Gene Expression

Gantois, I., Ducatelle, R., Pasmans, F., Haesebrouck, F., Hautefort, I., Thompson, A., Hinton, J. C. D., & Immerseel, F. V. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.1.946-949.2006 · Cited by 378 · see citing works

Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice

Faith, J. J., Ahern, P. P., Ridaura, V. K., Cheng, J., & Gordon, J. I. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008051 · Cited by 373 · see citing works

A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism

Russell, A. B., Wexler, A. G., Harding, B. N., Whitney, J. C. C., Bohn, A., Goo, Y. A., Tran, B. Q., Barry, N. A., Zheng, H., Peterson, S. B., et al. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.07.007 · Cited by 369 · see citing works

Effect of Streptomycin on Susceptibility of Intestinal Tract to Experimental Salmonella Infection.

Bohnhoff, M., Drake, B. L., & Miller, C. P. (1954) · Experimental Biology and Medicine · doi:10.3181/00379727-86-21030 · Cited by 354 · see citing works

Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota

Josefsdottir, K. S., Baldridge, M. T., Kadmon, C. S., & King, K. Y. (2017) · Blood · doi:10.1182/blood-2016-03-708594 · Cited by 343 · see citing works

Mechanisms That Control Bacterial Populations in Continuous-Flow Culture Models of Mouse Large Intestinal Flora

Freter, R., Brickner, H., Botney, M. D., Cleven, D., & Aranki, A. (1983) · Infection and Immunity · doi:10.1128/iai.39.2.676-685.1983 · Cited by 340 · see citing works

T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment.

Dianda, L., Hanby, A., Wright, N. A., Sebesteny, A., Hayday, A., & Owen, M. J. (1997) · Europe PMC (PubMed Central) · Cited by 337 · see citing works

Tissue‐resident macrophages: then and now

Davies, L. C., & Taylor, P. R. (2015) · Immunology · doi:10.1111/imm.12451 · Cited by 333 · see citing works

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

Shaw, M. H., Kamada, N., Yun-Gi, K., & Núñez, G. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20111703 · Cited by 331 · see citing works

Culture-Independent Analyses of Temporal Variation of the Dominant Fecal Microbiota and Targeted Bacterial Subgroups in Crohn's Disease

Scanlan, P. D., Shanahan, F., O'Mahony, C., & Marchesi, J. R. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.00312-06 · Cited by 330 · see citing works

Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut

Liu, J. Z., Jellbauer, S., Poe, A. J., Ton, V., Pesciaroli, M., Kehl-Fie, T. E., Restrepo, N. A., Hosking, M. P., Edwards, R. A., Battistoni, A., et al. (2012) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2012.01.017 · Cited by 328 · see citing works

The dynamics of gut‐associated microbial communities during inflammation

Winter, S., Lopez, C. A., & Bäumler, A. J. (2013) · EMBO Reports · doi:10.1038/embor.2013.27 · Cited by 328 · see citing works

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

Seo, S.-U., Kamada, N., Muñoz-Planillo, R., Kim, Y.-G., Kim, D., Koizumi, Y., Hasegawa, M., Himpsl, S. D., Browne, H. P., Lawley, T. D., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.03.004 · Cited by 318 · see citing works

Ethanolamine utilization in bacterial pathogens: roles and regulation

Garsin, D. A. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2334 · Cited by 318 · see citing works

The bacterial LexA transcriptional repressor

Butala, M., Žgur-Bertok, D., & Busby, S. J. W. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8378-6 · Cited by 315 · see citing works

Maternal IgG and IgA Antibodies Dampen Mucosal T Helper Cell Responses in Early Life

Koch, M. A., Reiner, G. L., Lugo, K. A., Kreuk, L. S. M., Stanbery, A. G., Ansaldo, E., Seher, T. D., Ludington, W. B., & Barton, G. M. (2016) · Cell · doi:10.1016/j.cell.2016.04.055 · Cited by 315 · see citing works

Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly

Lapaquette, P., Glasser, A.-L., Huett, A. S., Xavier, R. J., & Darfeuille–Michaud, A. (2009) · Cellular Microbiology · doi:10.1111/j.1462-5822.2009.01381.x · Cited by 312 · see citing works

Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers

Krogius-Kurikka, L., Lyra, A., Malinen, E., Aarnikunnas, J., Tuimala, J., Paulin, L. G., Mäkivuokko, H., Kajander, K., & Palva, A. (2009) · BMC Gastroenterology · doi:10.1186/1471-230x-9-95 · Cited by 307 · see citing works

Oral Treatment with Live Lactobacillus reuteri Inhibits the Allergic Airway Response in Mice

Forsythe, P., Inman, M. D., & Bienenstock, J. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200606-821oc · Cited by 306 · see citing works

Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

Pham, T. A. N., Clare, S., Goulding, D., Arasteh, J. M., Stares, M. D., Browne, H. P., Keane, J. A., Page, A. J., Kumasaka, N., Kane, L., et al. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.08.017 · Cited by 305 · see citing works

Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome – a longitudinal study in IBS and control subjects

Mättö, J., Maunuksela, L., Kajander, K., Palva, A., Korpela, R., Kassinen, A., & Saarela, M. (2005) · FEMS Immunology &amp; Medical Microbiology · doi:10.1016/j.femsim.2004.08.009 · Cited by 301 · see citing works

Role of competition for nutrients in suppression of Clostridium difficile by the colonic microflora

Wilson, K. H., & Perini, F. (1988) · Infection and Immunity · doi:10.1128/iai.56.10.2610-2614.1988 · Cited by 297 · see citing works

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome

McNulty, N. P., Wu, M., Erickson, A. R., Pan, C., Erickson, B. K., Martens, E. C., Pudlo, N. A., Muegge, B. D., Henrissat, B., Hettich, R. L., et al. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001637 · Cited by 295 · see citing works

Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection

Abt, M. C., Lewis, B. B., Caballero, S., Xiong, H., Carter, R. A., Sušac, B., Ling, L., Leiner, I. M., & Pamer, E. G. (2015) · Cell Host & Microbe · doi:10.1016/j.chom.2015.06.011 · Cited by 293 · see citing works

Microbial colonization influences early B-lineage development in the gut lamina propria

Wesemann, D. R., Portuguese, A. J., Meyers, R. M., Gallagher, M. P., Cluff-Jones, K., Magee, J. M., Panchakshari, R. A., Rodig, S. J., Kepler, T. B., & Alt, F. W. (2013) · Nature · doi:10.1038/nature12496 · Cited by 286 · see citing works

Lactoferrin and host defense

Ward, P. P., Uribe-Luna, S., & Conneely, O. M. (2002) · Biochemistry and Cell Biology · doi:10.1139/o01-214 · Cited by 283 · see citing works

Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease

Shaw, K. A., Bertha, M., Hofmekler, T., Chopra, P., Vatanen, T., Srivatsa, A., Prince, J., Kumar, A., Sauer, C. G., Zwick, M. E., et al. (2016) · Genome Medicine · doi:10.1186/s13073-016-0331-y · Cited by 278 · see citing works

Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohnʼs disease: A randomized, double-blind, placebo-controlled pilot study

Thia, K. T. J., Mahadevan, U., Feagan, B. G., Wong, C. J., Cockeram, A. W., Bitton, A., Bernstein, C. N., & Sandborn, W. J. (2008) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20608 · Cited by 276 · see citing works

Microbiota-Derived Compounds Drive Steady-State Granulopoiesis via MyD88/TICAM Signaling

Balmer, M. L., Schürch, C. M., Saito, Y., Geuking, M. B., Li, H., Miguelangel Cuenca, V., Kovtonyuk, L. V., McCoy, K. D., Hapfelmeier, S., Ochsenbein, A. F., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400762 · Cited by 274 · see citing works

Innate Lymphoid Cell Interactions with Microbiota: Implications for Intestinal Health and Disease

Sonnenberg, G. F., & Artis, D. (2012) · Immunity · doi:10.1016/j.immuni.2012.10.003 · Cited by 272 · see citing works

Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens

Kim, Y., Sakamoto, K., Seo, S., Pickard, J. M., Gillilland, M. G., Pudlo, N. A., Hoostal, M. J., Li, X., Wang, T. D., Feehley, T., et al. (2017) · Science · doi:10.1126/science.aag2029 · Cited by 272 · see citing works

A composite bacteriophage alters colonization by an intestinal commensal bacterium

Duerkop, B. A., Clements, C. V., Rollins, D., Rodrigues, J. L. M., & Hooper, L. V. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206136109 · Cited by 259 · see citing works

Regulation of Cytokine Secretion in Human CD127+ LTi-like Innate Lymphoid Cells by Toll-like Receptor 2

Crellin, N. K., Trifari, S., Kaplan, C. D., Satoh‐Takayama, N., Santo, J. P. D., & Spits, H. (2010) · Immunity · doi:10.1016/j.immuni.2010.10.012 · Cited by 252 · see citing works

RESISTANCE OF THE MOUSE'S INTESTINAL TRACT TO EXPERIMENTAL SALMONELLA INFECTION

Bohnhoff, M., Miller, C. P., & Martin, W. R. (1964) · The Journal of Experimental Medicine · doi:10.1084/jem.120.5.805 · Cited by 246 · see citing works

Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice

Huang, Y., Chassard, C., Hausmann, M., von Itzstein, M., & Hennet, T. (2015) · Nature Communications · doi:10.1038/ncomms9141 · Cited by 242 · see citing works

Phage-Mediated Acquisition of a Type III Secreted Effector Protein Boosts Growth of Salmonella by Nitrate Respiration

Lopez, C. A., Winter, S., Rivera-Chávez, F., Byndloss, M. X., Poon, V., Nuccio, S., Tsolis, R. M., & Bäumler, A. J. (2012) · mBio · doi:10.1128/mbio.00143-12 · Cited by 242 · see citing works

Streptomycin-Induced Inflammation Enhances Escherichia coli Gut Colonization Through Nitrate Respiration

Spees, A. M., Wangdi, T., Lopez, C. A., Kingsbury, D. D., Byndloss, M. X., Winter, S., Tsolis, R. M., & Bäumler, A. J. (2013) · mBio · doi:10.1128/mbio.00430-13 · Cited by 237 · see citing works

Short‐chain organic acids at pH 5.0 kill <i>Escherichia coli</i> and <i>Salmonella</i> spp. without causing membrane perturbation

Cherrington, C. A., Hinton, M., Pearson, G. R., & Chopra, I. (1991) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1991.tb04442.x · Cited by 225 · see citing works

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

Raetz, M. M., Hwang, S., Wilhelm, C. L., Kirkland, D., Benson, A., Sturge, C. R., Mirpuri, J., Vaishnava, S., Hou, B., DeFranco, A. L., et al. (2012) · Nature Immunology · doi:10.1038/ni.2508 · Cited by 217 · see citing works

Human symbionts inject and neutralize antibacterial toxins to persist in the gut

Wexler, A. G., Bao, Y., Whitney, J. C. C., Bobay, L., Xavier, J. B., Schofield, W. B., Barry, N. A., Russell, A. B., Tran, B. Q., Goo, Y. A., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1525637113 · Cited by 216 · see citing works

Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota

Ayres, J. S., Trinidad, N. J., & Vance, R. E. (2012) · Nature Medicine · doi:10.1038/nm.2729 · Cited by 213 · see citing works

CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiomePreprint

Stern, A., Mick, E., Tirosh, I., Sagy, O., & Sorek, R. (2012) · Genome Research · doi:10.1101/gr.138297.112 · Cited by 212 · see citing works

Chaperone function of FkpA, a heat shock prolyl isomerase, in the periplasm ofEscherichia coli

Arié, J., Sassoon, N., & Betton, J. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02250.x · Cited by 208 · see citing works

Interleukin-1β Selectively Expands and Sustains Interleukin-22+ Immature Human Natural Killer Cells in Secondary Lymphoid Tissue

Hughes, T. L., Becknell, B., Freud, A. G., McClory, S., Briercheck, E. L., Yu, J., Mao, C., Giovenzana, C., Nuovo, G. J., Wei, L., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.06.007 · Cited by 207 · see citing works

The Mucin Muc2 Limits Pathogen Burdens and Epithelial Barrier Dysfunction during Salmonella enterica Serovar Typhimurium Colitis

Zarepour, M., Bhullar, K., Montero, M., Ma, C., Huang, T., Velcich, A., Xia, L., & Vallance, B. A. (2013) · Infection and Immunity · doi:10.1128/iai.00854-13 · Cited by 206 · see citing works

Inflammation boosts bacteriophage transfer between Salmonella spp.

Diard, M., Bakkeren, E., Cornuault, J. K., Moor, K., Hausmann, A., Sellin, M. E., Loverdo, C., Aertsen, A., Ackermann, M., Paepe, M. D., et al. (2017) · Science · doi:10.1126/science.aaf8451 · Cited by 205 · see citing works

Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media

Bouchet, V., Hood, D. W., Li, J., Brisson, J., Randle, G. A., Martin, A., Li, Z., Goldstein, R., Schweda, E. K. H., Pelton, S. I., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432026100 · Cited by 204 · see citing works

Virulence factors enhance <i>Citrobacter rodentium</i> expansion through aerobic respiration

Lopez, C. A., Miller, B. M., Rivera-Chávez, F., Velazquez, E. M., Byndloss, M. X., Chávez-Arroyo, A., Lokken, K. L., Tsolis, R. M., Winter, S. E., & Bäumler, A. J. (2016) · Science · doi:10.1126/science.aag3042 · Cited by 201 · see citing works

RESISTANCE OF THE MOUSE'S INTESTINAL TRACT TO EXPERIMENTAL SALMONELLA INFECTION

Bohnhoff, M., Miller, C. P., & Martin, W. R. (1964) · The Journal of Experimental Medicine · doi:10.1084/jem.120.5.817 · Cited by 196 · see citing works

Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes

Nash, J. J., Villegas, A., Kropinski, A. M., Aguilar‐Valenzuela, R., Konczy, P., Mascarenhas, M., Ziebell, K. A., Torres, A. G., Karmali, M. A., & Coombes, B. K. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-667 · Cited by 194 · see citing works

What is type VI secretion doing in all those bugs?

Schwarz, S., Hood, R. D., & Mougous, J. D. (2010) · Trends in Microbiology · doi:10.1016/j.tim.2010.09.001 · Cited by 194 · see citing works

The Fatal Enteric Cholera Infection in the Guinea Pig, Achieved by Inhibition of Normal Enteric Flora

Freter, R. (1955) · The Journal of Infectious Diseases · doi:10.1093/infdis/97.1.57 · Cited by 194 · see citing works

Infection Mobilizes Hematopoietic Stem Cells through Cooperative NOD-like Receptor and Toll-like Receptor Signaling

Burberry, A., Zeng, M. Y., Ding, L., Wicks, I. P., Inohara, N., Morrison, S. J., & Núñez, G. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.05.004 · Cited by 191 · see citing works

Mucosal lipocalin 2 has pro-inflammatory and iron-sequestering effects in response to bacterial enterobactin

Bachman, M. A., Miller, V. L., & Weiser, J. N. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000622 · Cited by 186 · see citing works

Strain competition restricts colonization of an enteric pathogen and prevents colitis

Hecht, A. L., Casterline, B. W., Earley, Z. M., Goo, Y. A., Goodlett, D. R., & Wardenburg, J. B. (2016) · EMBO Reports · doi:10.15252/embr.201642282 · Cited by 182 · see citing works

Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion

Faber, F., Tran, L., Byndloss, M. X., Lopez, C. A., Velazquez, E. M., Kerrinnes, T., Nuccio, S., Wangdi, T., Fiehn, O., Tsolis, R. M., et al. (2016) · Nature · doi:10.1038/nature18597 · Cited by 180 · see citing works

Generation of Polymeric Immunoglobulin Receptor-Deficient Mouse with Marked Reduction of Secretory IgA

Shimada, S.-I., Kawaguchi-Miyashita, M., Kushiro, A., Sato, T., Nanno, M., Sako, T., Matsuoka, Y., Sudo, K., Tagawa, Y., Iwakura, Y., et al. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.10.5367 · Cited by 177 · see citing works

Point Mutations in FimH Adhesin of Crohn's Disease-Associated Adherent-Invasive Escherichia coli Enhance Intestinal Inflammatory Response

Dreux, N., Denizot, J., Martínez-Medina, M., Mellmann, A., Billig, M., Kisiela, D., Chattopadhyay, S., Sokurenko, E. V., Neut, C., Gower‐Rousseau, C., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003141 · Cited by 177 · see citing works

Antibiotics increase functional abdominal symptoms

Maxwell, P., Rink, E., Kumar, D., & Mendall, M. A. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05428.x · Cited by 176 · see citing works

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

Bergström, J. H., Birchenough, G. M. H., Katona, G., Schroeder, B. O., Schütte, A., Ermund, A., Johansson, M., & Hansson, G. C. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1611400113 · Cited by 176 · see citing works

Intestinal Muc2 mucin O-glycosylation is affected by microbiota and regulated by differential expression of glycosyltranferases

Arike, L., Holmén‐Larsson, J., & Hansson, G. C. (2017) · Glycobiology · doi:10.1093/glycob/cww134 · Cited by 176 · see citing works

Homeland Security: IgA immunity at the frontiers of the body

Macpherson, A. J., Geuking, M. B., & McCoy, K. D. (2012) · Trends in Immunology · doi:10.1016/j.it.2012.02.002 · Cited by 174 · see citing works

Rifaximin-Extended Intestinal Release Induces Remission in Patients With Moderately Active Crohn's Disease

Prantera, C., Lochs, H. H., Grimaldi, M., Danese, S., Scribano, M. L., & Gionchetti, P. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.11.032 · Cited by 174 · see citing works

Salmonella Uses Energy Taxis to Benefit from Intestinal Inflammation

Rivera-Chávez, F., Winter, S., Lopez, C. A., Byndloss, M. X., Winter, M. G., Nuccio, S., Russell, J. M., Laughlin, R. C., Lawhon, S. D., Sterzenbach, T., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003267 · Cited by 170 · see citing works

Anti-infective properties of bacteriocins: an update

Hammami, R., Fernandez, B., Lacroix, C., & Fliss, I. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1202-3 · Cited by 165 · see citing works

Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration

Diaz-Ochoa, V. E., Lam, D., Lee, C. S., Klaus, S., Behnsen, J., Liu, J. Z., Chim, N., Nuccio, S.-P., Rathi, S. G., Mastroianni, J. R., et al. (2016) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2016.05.005 · Cited by 164 · see citing works

Inflammation-associated Adherent-invasive Escherichia coli Are Enriched in Pathways for Use of Propanediol and Iron and M-cell Translocation

Dogan, B., Suzuki, H., Herlekar, D., Sartor, R. B., Campbell, B. J., Roberts, C. L., Stewart, K., Scherl, E., Araz, Y., Bitar, P. P., et al. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000183 · Cited by 158 · see citing works

Antibiotic use, childhood affluence and irritable bowel syndrome (IBS)

Mendall, M. A., & Kumar, D. (1998) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-199801000-00011 · Cited by 155 · see citing works

Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

Yi, M., Zheng, X., Niu, M., Zhu, S., Ge, H., & Wu, K. (2022) · Molecular Cancer · doi:10.1186/s12943-021-01489-2 · Cited by 1,445 · see citing works

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

Jalili-Firoozinezhad, S., Gazzaniga, F. S., Calamari, E. L., Camacho, D. M., Fadel, C. W., Bein, A., Swenor, B., Nestor, B., Cronce, M. J., Tovaglieri, A., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0397-0 · Cited by 855 · see citing works

Oral microbiomes: more and more importance in oral cavity and whole body

Gao, L., Xu, T., Huang, G., Jiang, S., Gu, Y., & Chen, F. (2018) · Protein &amp; Cell · doi:10.1007/s13238-018-0548-1 · Cited by 770 · see citing works

Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection

Ducarmon, Q. R., Zwittink, R. D., Hornung, B. V. H., van Schaik, W., Young, V. B., & Kuijper, E. J. (2019) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00007-19 · Cited by 566 · see citing works

Microbiota-mediated colonization resistance: mechanisms and regulation

Caballero-Flores, G., Pickard, J. M., & Núñez, G. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00833-7 · Cited by 474 · see citing works

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

Das, N. K., Schwartz, A. J., Barthel, G., Inohara, N., Liu, Q., Sankar, A., Hill, D. R., Ma, X., Lamberg, O., Schnizlein, M. K., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2019.10.005 · Cited by 331 · see citing works

Polyamines and gut microbiota

Tofalo, R., Cocchi, S., & Suzzi, G. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00016 · Cited by 306 · see citing works

Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases

Opazo, M. C., Ortega-Rocha, E. M., Coronado-Arrázola, I., Bonifaz, L. C., Boudin, H., Neunlist, M., Bueno, S. M., Kalergis, A. M., & Riedel, C. A. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00432 · Cited by 179 · see citing works

Dietary Fiber-Induced Microbial Short Chain Fatty Acids Suppress ILC2-Dependent Airway Inflammation

Lewis, G., Wang, B., Shafiei Jahani, P., Hurrell, B. P., Banie, H., Aleman Muench, G. R., Maazi, H., Helou, D. G., Howard, E., Galle-Treger, L., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02051 · Cited by 163 · see citing works

Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer’s Disease

Gaitán, J. M., Moon, H. Y., Stremlau, M., Dubal, D. B., Cook, D. B., Okonkwo, O. C., & van Praag, H. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.660181 · Cited by 160 · see citing works

Multiscale Evolutionary Dynamics of Host-Associated Microbiomes

Ferreiro, A., Crook, N., Gasparrini, A. J., & Dantas, G. (2018) · Cell · doi:10.1016/j.cell.2018.02.015 · Cited by 127 · see citing works

Dimethyl itaconate ameliorates cognitive impairment induced by a high-fat diet via the gut-brain axis in mice

Pan, W., Zhao, J., Wu, J., Xu, D., Meng, X., Jiang, P., Shi, H., Ge, X., Yang, X., Hu, M., et al. (2023) · Microbiome · doi:10.1186/s40168-023-01471-8 · Cited by 113 · see citing works

Oxidative Stress and Gut-Derived Lipopolysaccharides in Neurodegenerative Disease: Role of NOX2

Loffredo, L., Ettorre, E., Zicari, A. M., Inghilleri, M., Nocella, C., Perri, L., Spalice, A., Fossati, C., De Lucia, M. C., Pigozzi, F., et al. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/8630275 · Cited by 100 · see citing works

Role of the gut microbiota in nutrient competition and protection against intestinal pathogen colonization

Horrocks, V., King, O. G., Yip, A. Y. G., Marques, I. M., & McDonald, J. A. K. (2023) · Microbiology · doi:10.1099/mic.0.001377 · Cited by 104 · see citing works

Pathogenic E. coli Extracts Nutrients from Infected Host Cells Utilizing Injectisome Components

Pal, R. R., Baidya, A. K., Mamou, G., Bhattacharya, S., Socol, Y., Kobi, S., Katsowich, N., Ben-Yehuda, S., & Rosenshine, I. (2019) · Cell · doi:10.1016/j.cell.2019.02.022 · Cited by 72 · see citing works

Cow’s Milk Allergy: Immunomodulation by Dietary Intervention

D’Auria, E., Salvatore, S., Pozzi, E., Mantegazza, C., Sartorio, M. U. A., Pensabene, L., Baldassarre, M. E., Agosti, M., Vandenplas, Y., & Zuccotti, G. (2019) · Nutrients · doi:10.3390/nu11061399 · Cited by 70 · see citing works

Manipulating Gut Microbiota Composition to Enhance the Therapeutic Effect of Cancer Immunotherapy

Yi, M., Jiao, D., Qin, S., Chu, Q., Li, A., & Wu, K. (2019) · Integrative Cancer Therapies · doi:10.1177/1534735419876351 · Cited by 69 · see citing works

Current Progress and Future Perspectives of Immune Checkpoint in Cancer and Infectious Diseases

Cai, X., Zhan, H., Ye, Y., Yang, J., Zhang, M., Li, J., & Zhuang, Y. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.785153 · Cited by 66 · see citing works

Gut-Brain Axis: Probiotic,<i>Bacillus subtilis</i>, Prevents Aggression via the Modification of the Central Serotonergic System

Cheng, H.-W., Jiang, S., & Hu, J. (2019) · Oral Health by Using Probiotic Products · doi:10.5772/intechopen.86775 · Cited by 17 · see citing works

Impaired Colonization Defence of the Oropharynx

JOHANSON, W. G. (1989) · Update in intensive care and emergency medicine · doi:10.1007/978-3-642-83752-4_7 · Cited by 3 · see citing works

Microbiological factors affecting the colonization of tomato roots byRalstonia solanacearumYU1Rif43lux

Toyota, K., Kimura, M., & Kinoshita, T. (2000) · Soil Science & Plant Nutrition · doi:10.1080/00380768.2000.10409129 · Cited by 14 · see citing works

The Influence of Climate Factor on Betula albo-sinensis's Colonization and Colonization Intensity by AMF

Li, W. (2005) · Sichuan linye ke-ji

Co-colonization with multiple different species of multidrug-resistant gram-negative bacteria

Snyder, G. M., O’Fallon, E., & D’Agata, E. M. C. (2011) · American Journal of Infection Control · doi:10.1016/j.ajic.2010.09.012 · Cited by 30 · see citing works

Environmental and genetic effects on the formation of ectomycorrhizal and arbuscular mycorrhizal associations in cottonwoods

Gehring, C. A., Mueller, R., & Whitham, T. G. (2006) · Oecologia · doi:10.1007/s00442-006-0437-9 · Cited by 153 · see citing works