Cited by 436Psoriasis: Treatment and PathogenesisDermatology and Skin DiseasesMental Health Treatment and Access

The DOI matches its Crossref record; 73 of the 77 references it cites were found in a registry or an index.

The Prevalence and Odds of Depressive Symptoms and Clinical Depression in Psoriasis Patients: A Systematic Review and Meta-Analysis

Open access

Dowlatshahi, Emmilia A., Wakkee, Marlies, Arends, Lidia R., Nijsten, Tamar·2014·Journal of Investigative Dermatology

DOI 10.1038/jid.2013.508

Open this paper in CoChat — free account

Abstract

The reported prevalence of depression in psoriasis varies substantially. This study aims to determine the prevalence and odds of depressive symptoms and clinical depression in psoriasis. A systematic literature search was conducted. Mean questionnaire values and proportions for depressive symptoms and clinical depression were pooled according to different assessment methods. In controlled studies, standardized mean differences (SMDs) and odds ratio (OR) compared depression in psoriasis patients with controls using the random-effect model. The majority of the 98 eligible studies were conducted in tertiary centers without a control group. The prevalence of depressive symptoms was 28% using questionnaires and the prevalence of clinical depression was 12% using International Classification of Diseases codes, 19% using Diagnostic and Statistical Manual of Mental Disorders IV, and 9% for antidepressant use. Psoriasis patients had significantly more depressive symptoms (SMD 1.16; 95% confidence interval (CI) 0.67-1.66), and population-based studies showed that they were at least one and a half times more likely to experience depression (OR 1.57; 95% CI 1.40-1.76) and used more antidepressants than did controls (OR 4.24, 95% CI 1.53-11.76). More than 10% of psoriasis patients suffer from clinical depression, and twice as many have depressive symptoms. The high prevalence of these symptoms is likely to be affected by the tertiary study populations and differential misclassification using questionnaires, where psoriasis-related symptoms may be detected as depressive symptoms.

Integrity signals

Registry

Crossref · 10.1038/jid.2013.508

Cites

73 of 73 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763
Untitled work
(1992) · PubMed · Cited by 33,716
A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
Untitled work
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139

Show all 77 references

Research works printed but not linked: 3

Chan, 2009, Depression in Hong Kong Chinese patients with psoriasis, Hong Kong J Dermatol Venereol, 17, 69
Dowlatshahi, 2011, Antidepressant drug use in patients with psoriasis: a population based cohort study, J Invest Dermatol, 131, S48
Zhang, 2011, Prevalence of autoimmune diseases and other comorbidities in patients with psoriatic arthritis in the United States, Arthritis Care Res, 63, 1333

Sorted by citations

Pathophysiology, Clinical Presentation, and Treatment of Psoriasis
Armstrong, A. W., & Read, C. (2020) · JAMA · doi:10.1001/jama.2020.4006 · Cited by 2,364
Psoriasis and comorbid diseases
Takeshita, J., Grewal, S. K., Langan, S., Mehta, N. N., Ogdie, A., Voorhees, A. S. V., & Gelfand, J. M. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2016.07.064 · Cited by 1,228
The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries
Dalgard, F. J., Gieler, U., Tomas-Aragones, L., Lien, L., Poot, F., Jemec, G. B. E., Misery, L., Szabo, C., Linder, D., Sampogna, F., et al. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.530 · Cited by 968
Comorbid depression in medical diseases
Gold, S. M., Köhler‐Forsberg, O., Moss-Morris, R. E., Mehnert-Theuerkauf, A., Miranda, J. J., Bullinger, M., Steptoe, A., Whooley, M. A., & Otte, C. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0200-2 · Cited by 583
Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities
Elmets, C. A., Leonardi, C. L., Davis, D. M. R., Gelfand, J. M., Lichten, J. B., Mehta, N. N., Armstrong, A. W., Connor, C. J., Cordoro, K. M., Elewski, B. E., et al. (2019) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2018.11.058 · Cited by 542
Prevalence and odds of S taphylococcus aureus carriage in atopic dermatitis: a systematic review and meta-analysis
Totté, J. E. E., van der Feltz, W. T., Hennekam, M., van Belkum, A., van Zuuren, E. J., & Pasmans, S. G. M. A. (2016) · British Journal of Dermatology · doi:10.1111/bjd.14566 · Cited by 470
Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies
Köhler, C. A., Evangelou, E., Stubbs, B., Solmi, M., Veronese, N., Belbasis, L., Bortolato, B., Melo, M. C. A., Coelho, C. A., Fernandes, B. S., et al. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.05.020 · Cited by 302
Neutrophils in Psoriasis
Chiang, C.-C., Cheng, W.-J., Kořínek, M., Lin, C.-Y., & Hwang, T. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02376 · Cited by 300
Efficacy and Safety of Biologics for Psoriasis and Psoriatic Arthritis and Their Impact on Comorbidities: A Literature Review
Kamata, M., & Tada, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051690 · Cited by 238
Psoriasis and suicidality: A systematic review and meta-analysis
Singh, S., Taylor, C., Kornmehl, H. A., & Armstrong, A. W. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.05.019 · Cited by 247
Psoriasis and comorbid diseases
Takeshita, J., Grewal, S. K., Langan, S., Mehta, N. N., Ogdie, A., Voorhees, A. S. V., & Gelfand, J. M. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2016.07.065 · Cited by 242
Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment
Guttman‐Yassky, E., Krueger, J. G., & Lebwohl, M. (2017) · Experimental Dermatology · doi:10.1111/exd.13336 · Cited by 233
Psoriasis
Armstrong, A. W., Blauvelt, A., Duffin, K. C., Huang, Y., Savage, L. J., Guo, L., & Merola, J. F. (2025) · Nature Reviews Disease Primers · doi:10.1038/s41572-025-00630-5 · Cited by 271
Depression and suicidality in psoriasis: review of the literature including the cytokine theory of depression
Koo, J. Y. M., Marangell, L. B., Nakamura, M., Armstrong, A. W., Jeon, C., Bhutani, T., & Wu, J. J. (2017) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.14460 · Cited by 214
Psoriasis and Cardiovascular Comorbidities: Focusing on Severe Vascular Events, Cardiovascular Risk Factors and Implications for Treatment
Hu, S. C., & Lan, C.-C. E. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18102211 · Cited by 199
Long-term safety and tolerability of apremilast in patients with psoriasis: Pooled safety analysis for ≥156 weeks from 2 phase 3, randomized, controlled trials (ESTEEM 1 and 2)
Crowley, J., Thaçi, D., Joly, P., Peris, K., Papp, K. A., Goncalves, J., Day, R. M., Chen, R., Shah, K., Ferrándiz, C., et al. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.01.052 · Cited by 193
Understanding the prospective of nano-formulations towards the treatment of psoriasis
Pradhan, M., Alexander, A., Singh, M. R., Singh, D., Saraf, S., Saraf, S., & Ajazuddin, M. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.07.156 · Cited by 177
Psoriasis and sleep disorders: A systematic review
Gupta, M. A., Simpson, F. C., & Gupta, A. K. (2015) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.09.003 · Cited by 166
The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases
Harden, J. L., Lewis, S. M., Lish, S. R., Suárez‐Fariñas, M., Gareau, D. S., Lentini, T., Johnson-Huang, L. M., Krueger, J. G., & Lowes, M. A. (2015) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.09.055 · Cited by 158
Certolizumab pegol for the treatment of chronic plaque psoriasis: Results through 48 weeks from 2 phase 3, multicenter, randomized, double-blinded, placebo-controlled studies (CIMPASI-1 and CIMPASI-2)
Gottlieb, A. B., Blauvelt, A., Thaçi, D., Leonardi, C. L., Poulin, Y. P., Drew, J., Peterson, L., Arendt, C. H., Burge, D. J., & Reich, K. (2018) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2018.04.012 · Cited by 157
The prevalence of anxiety in patients with psoriasis: a systematic review of observational studies and clinical trials
Fleming, P., Bai, J., Pratt, M. E., Sibbald, C. J., Lynde, C. W., & Gulliver, W. P. F. (2016) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.13891 · Cited by 164
Depression and Anxiety in Adults With Hidradenitis Suppurativa
Machado, M. O., Stergiopoulos, V., Maes, M. H. J., Kurdyak, P. A., Lin, P.-Y., Wang, L., Shyu, Y., Firth, J., Koyanagi, A., Solmi, M., et al. (2019) · JAMA Dermatology · doi:10.1001/jamadermatol.2019.0759 · Cited by 164
Psoriasis and the Risk of Depression in the US Population
Cohen, B. E., Martires, K. J., & Ho, R. S. (2015) · JAMA Dermatology · doi:10.1001/jamadermatol.2015.3605 · Cited by 152
Treatment of Psoriasis: A Comprehensive Review of Entire Therapies
Bakshi, H., Nagpal, M., Singh, M., Dhingra, G. A., & Aggarwal, G. (2020) · Current Drug Safety · doi:10.2174/1574886315666200128095958 · Cited by 143
The Involvement of TNF-α in Cognitive Dysfunction Associated with Major Depressive Disorder: An Opportunity for Domain Specific Treatments
Bortolato, B., F. Carvalho, A., K. Soczynska, J., I. Perini, G., & S. McIntyre, R. (2015) · Current Neuropharmacology · doi:10.2174/1570159x13666150630171433 · Cited by 142
Safety of biologics in psoriasis
Kamata, M., & Tada, Y. (2017) · The Journal of Dermatology · doi:10.1111/1346-8138.14096 · Cited by 133
Psychosocial burden of localised cutaneous Leishmaniasis: a scoping review
Bennis, I., Brouwere, V. D., Belrhiti, Z., Sahibi, H., & Boelaert, M. (2018) · BMC Public Health · doi:10.1186/s12889-018-5260-9 · Cited by 131
Depressive symptoms, depression, and the effect of biologic therapy among patients in Psoriasis Longitudinal Assessment and Registry (PSOLAR)
Strober, B. E., Gooderham, M., de Jong, E. M. G. J., Kimball, A. B., Langley, R. G. B., Lakdawala, N. R., Goyal, K., Lawson, F. L., Langholff, W. K., Hopkins, L., et al. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.08.051 · Cited by 123
Screening for anxiety and depression in people with psoriasis: a cross-sectional study in a tertiary referral setting
Lamb, R. C., Matcham, F., Turner, M. A., Rayner, L., Simpson, A., Hotopf, M. H., Barker, J. N., Jackson, K., & Smith, C. H. (2016) · British Journal of Dermatology · doi:10.1111/bjd.14833 · Cited by 121
Safety and efficacy of brodalumab for psoriasis after 120 weeks of treatment
Papp, K. A., Leonardi, C. L., Menter, A., Thompson, E. H. Z., Milmont, C. E., Kricorian, G., Nirula, A., & Klekotka, P. A. (2014) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2014.08.039 · Cited by 116
Impact of Ixekizumab Treatment on Depressive Symptoms and Systemic Inflammation in Patients with Moderate-to-Severe Psoriasis: An Integrated Analysis of Three Phase 3 Clinical Studies
Griffiths, C. E. M., Fava, M., Miller, A. H., Russell, J., Ball, S. G., Xu, W., Acharya, N., & Rapaport, M. H. (2017) · Psychotherapy and Psychosomatics · doi:10.1159/000479163 · Cited by 115
Associations between psoriasis and mental illness: an update for clinicians
Hedemann, T. L., Liu, X., Kang, C. N.-Y., & Husain, M. I. (2022) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2022.01.006 · Cited by 112
Pediatric Psoriasis Comorbidity Screening Guidelines
Osier, E., Wang, A. S., Tollefson, M. M., Cordoro, K. M., Daniels, S. R., Eichenfield, A. H., Gelfand, J. M., Gottlieb, A. B., Kimball, A. B., Lebwohl, M., et al. (2017) · JAMA Dermatology · doi:10.1001/jamadermatol.2017.0499 · Cited by 111
The Challenge of Managing Psoriasis: Unmet Medical Needs and Stakeholder Perspectives.
Feldman, S. R., Goffe, B. S., Rice, G. K., Mitchell, M., Kaur, M., Robertson, D. H., Sierka, D., Bourret, J. A., Evans, T. S., & Gottlieb, A. B. (2016) · Europe PMC (PubMed Central) · Cited by 109
The Role of IL-17 Cytokines in Psoriasis
Mosca, M., Hong, J., Hadeler, E., Hakimi, M., Liao, W. J., & Bhutani, T. (2021) · ImmunoTargets and Therapy · doi:10.2147/itt.s240891 · Cited by 117
Effect of biologics on depressive symptoms in patients with psoriasis: a systematic review
Fleming, P., Roubille, C., Richer, V., Starnino, T., McCourt, C., McFarlane, A., Siu, S., Kraft, J. N., Lynde, C. W., Pope, J. E., et al. (2014) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12909 · Cited by 104
All-cause and cause-specific mortality in psoriasis: A systematic review and meta-analysis
Dhana, A. V., Yen, H., Yen, H., & Cho, E. (2018) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2018.12.037 · Cited by 96
Depression and the risk of autoimmune disease: a nationally representative, prospective longitudinal study
Andersson, N. W., Gustafsson, L. N., Okkels, N., Taha, F., Cole, S. W., Munk‐Jørgensen, P., & Goodwin, R. D. (2015) · Psychological Medicine · doi:10.1017/s0033291715001488 · Cited by 103
Anti-IL17 therapies for psoriasis
Silfvast‐Kaiser, A., Paek, S. Y., & Menter, A. (2018) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2019.1555235 · Cited by 93
Psoriasis, Depression, and Inflammatory Overlap: A Review
Patel, N., Nadkarni, A., Cardwell, L. A., Vera, N., Frey, C. D., Patel, N. N., & Feldman, S. R. (2017) · American Journal of Clinical Dermatology · doi:10.1007/s40257-017-0279-8 · Cited by 92
Real-world burden of comorbidities in US patients with psoriasis
Shah, K., Mellars, L., Changolkar, A. K., & Feldman, S. R. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2017.03.037 · Cited by 91
The impact of genital psoriasis on quality of life: a systematic review
Yang, E., Beck, K. M., Sanchez, I. M., Koo, J. Y. M., & Liao, W. J. (2018) · Psoriasis Targets and Therapy · doi:10.2147/ptt.s169389 · Cited by 91
Cutaneous and Systemic Psoriasis: Classifications and Classification for the Distinction
Yan, B., Chen, X., Ye, L., Chen, J., Zheng, M., & Man, X. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.649408 · Cited by 90
Risk of depression in women with psoriasis: a cohort study
Dommasch, E. D., Li, T., Okereke, O. I., Li, Y., Qureshi, A. A., & Cho, E. (2015) · British Journal of Dermatology · doi:10.1111/bjd.14032 · Cited by 84
Sleep disturbance in psoriasis: a case-controlled study
Jensen, P., Zachariae, C. O. C., Skov, L., & Zachariae, R. H. (2018) · British Journal of Dermatology · doi:10.1111/bjd.16702 · Cited by 87
Diagnosis and Management of Cutaneous Psoriasis: A Review
Brandon, A., Mufti, A., & Sibbald, R. G. (2019) · Advances in Skin & Wound Care · doi:10.1097/01.asw.0000550592.08674.43 · Cited by 83
Patients with Hidradenitis Suppurativa Have a High Psychiatric Disease Burden: A Finnish Nationwide Registry Study
Huilaja, L., Tiri, H., Jokelainen, J. J., Timonen, M., & Tasanen, K. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2017.06.020 · Cited by 82
The impact of gender and sex in psoriasis: What to be aware of when treating women with psoriasis
Guillet, C., Seeli, C., Meienberger, N., Maul, L. V., & Maul, J. (2022) · International Journal of Women’s Dermatology · doi:10.1097/jw9.0000000000000010 · Cited by 85
Mendelian Disorders of Cornification Caused by Defects in Intracellular Calcium Pumps: Mutation Update and Database for Variants in ATP2A2 and ATP2C1 Associated with Darier Disease and Hailey-Hailey Disease
Nellen, R. G. L., Steijlen, P. M., Steensel, M. A. M. V., Vreeburg, M., Contributors, E. P., Frank, J., & van Geel, M. (2016) · Human Mutation · doi:10.1002/humu.23164 · Cited by 78
Quality of life, anxiety and depressive symptoms in patients with psoriasis: A case-control study
Martínez-Ortega, J. M., Morillas, P. N., Muñoz-Negro, J. E., Gutiérrez-Rojas, L., González-Domenech, P., & Manuel Gurpegui, A. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109780 · Cited by 76
Reliability and validity of the Chinese version of the Patient Health Questionnaire-9 (C-PHQ-9) in patients with psoriasis: a cross-sectional study
Ye, X., Shu, H., Feng, X., Xia, D., Wang, Z.-Q., Mi, W., Yu, B., Zhang, X., & Li, C. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-033211 · Cited by 75
Role of neuroimmune circuits and pruritus in psoriasis
Ayasse, M. T., Buddenkotte, J., Alam, M. A., & Steinhoff, M. S. (2020) · Experimental Dermatology · doi:10.1111/exd.14071 · Cited by 76
The Role of IL-17 Cytokines in Psoriasis
Mosca, M., Hong, J. J., Hadeler, E. K., Hakimi, M., Liao, W. J., & Bhutani, T. (2021) · Dove Medical Press (Taylor and Francis Group) · Cited by 73
Psychosocial Burden of Psoriasis: A Systematic Literature Review of Depression Among Patients with Psoriasis
Luna, P. C., Chu, C., Fatani, M. I. A., Borlenghi, C. E., Adora, A., Llamado, L. J. Q., & Wee, J. (2023) · Dermatology and Therapy · doi:10.1007/s13555-023-01060-5 · Cited by 73
Prevalence and Odds of Depressive and Anxiety Disorders and Symptoms in Children and Adults With Alopecia Areata
Lauron, S., Plasse, C., Vaysset, M., Pereira, B., D'Incan, M., Rondepierre, F., & Jalenques, I. (2023) · JAMA Dermatology · doi:10.1001/jamadermatol.2022.6085 · Cited by 71
Psoriasis and Depression: The Role of Inflammation
González-Parra, S., & Daudén, E. (2019) · Actas Dermo-Sifiliográficas (English Edition) · doi:10.1016/j.adengl.2018.05.035 · Cited by 70
A systematic review and meta-analysis on Staphylococcus aureus carriage in psoriasis, acne and rosacea
Totté, J. E. E., van der Feltz, W. T., Bode, L. G. M., van Belkum, A., van Zuuren, E. J., & Pasmans, S. G. M. A. (2016) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-016-2647-3 · Cited by 77
Psoriasis y depresión: el papel de la inflamación
González‐Parra, S., & Daudén, E. (2018) · Actas Dermo-Sifiliográficas · doi:10.1016/j.ad.2018.05.009 · Cited by 67
Advances in the Application of Natural Products and the Novel Drug Delivery Systems for Psoriasis
Xie, J., Huang, S., Huang, H., Deng, X., Yue, P., Lin, J., Yang, M., Han, L., & Zhang, D. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.644952 · Cited by 67
Topical treatments for scalp psoriasis
Schlager, J. G., Rosumeck, S., Werner, R. N., Jacobs, A., Schmitt, J. M., Schlager, C., & Nast, A. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009687.pub2 · Cited by 67
Psoriasis and New-onset Depression: A Danish Nationwide Cohort Study
Jensen, P., Ahlehoff, O., Egeberg, A., Gislason, G., Hansen, P. R., & Skov, L. (2015) · Acta Dermato Venereologica · doi:10.2340/00015555-2183 · Cited by 67
How does stigma affect people with psoriasis?
Łakuta, P., Marcinkiewicz, K., Bergler-Czop, B. S., & Brzezińska-Wcisło, L. A. (2017) · Advances in Dermatology and Allergology · doi:10.5114/pdia.2016.62286 · Cited by 73
The prevalence and odds of anxiety and depression in children and adults with hidradenitis suppurativa: Systematic review and meta-analysis
Jalenques, I., Ciortianu, L., Pereira, B., D'Incan, M., Lauron, S., & Rondepierre, F. (2020) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2020.03.041 · Cited by 67
A Cross-sectional Study of Prevalence and Implications of Depression and Anxiety in Psoriasis
Lakshmy, S., Balasundaram, S., Sarkar, S., Audhya, M., & Subramaniam, E. (2015) · Indian Journal of Psychological Medicine · doi:10.4103/0253-7176.168587 · Cited by 66
Drug survival rates and reasons for drug discontinuation in psoriasis
Arnold, T., Schaarschmidt, M., Herr, R. M., Fischer, J. E., Goerdt, S., & Peitsch, W. K. (2016) · JDDG Journal der Deutschen Dermatologischen Gesellschaft · doi:10.1111/ddg.13152 · Cited by 65
Determinants of quality of life and psychological status in adults with psoriasis
Kwan, Z., Bong, Y. B., Tan, L. L., Lim, S. X., Yong, A. S. W., Ch’ng, C. C., Tan, M. P., & Ismail, R. (2018) · Archives of Dermatological Research · doi:10.1007/s00403-018-1832-x · Cited by 64
The Risk of Systemic Diseases in Those with Psoriasis and Psoriatic Arthritis: From Mechanisms to Clinic
Woo, Y. R., Park, C. J., Kang, H., & Kim, J. E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197041 · Cited by 64
Comorbidity in Adult Psoriasis: Considerations for the Clinician
Daugaard, C. A., Iversen, L., & Hjuler, K. F. (2022) · Psoriasis Targets and Therapy · doi:10.2147/ptt.s328572 · Cited by 62
Gender, Body Image and Social Support: Biopsychosocial Determinants of Depression Among Patients with Psoriasis
Wojtyna, E., Łakuta, P., Marcinkiewicz, K., Bergler-Czop, B. S., & Brzezińska-Wcisło, L. A. (2016) · Acta Dermato Venereologica · doi:10.2340/00015555-2483 · Cited by 64
Epidemiology of depression and anxiety in patients with psoriatic arthritis: A systematic review and meta-analysis
Zusman, E. Z., Howren, A. M., Park, J. Y. E., Dutz, J. P., & Vera, M. A. D. (2020) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2020.02.001 · Cited by 60
Common Fundamentals of Psoriasis and Depression
Hölsken, S., Krefting, F., Schedlowski, M., & Sondermann, W. (2021) · Acta Dermato Venereologica · doi:10.2340/actadv.v101.565 · Cited by 59
Depression and Insomnia in Patients With Psoriasis and Psoriatic Arthritis Taking Tumor Necrosis Factor Antagonists
Wu, C., Chang, Y.-T., Juan, C., Shen, J., Lin, Y.-P., Shieh, J., Liu, H., & Chen, Y. (2016) · Medicine · doi:10.1097/md.0000000000003816 · Cited by 58
Cross-sectional study of psychiatric comorbidities in patients with atopic dermatitis and nonatopic eczema, urticaria, and psoriasis
Ahn, H., Shin, M. K., Seo, J., Jeong, S. J., Cho, A. R., Choi, S.-H., & Lew, B. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s191509 · Cited by 57
Beyond skin deep: addressing comorbidities in psoriasis
Kovitwanichkanont, T., Chong, A. H., & Foley, P. A. (2020) · The Medical Journal of Australia · doi:10.5694/mja2.50591 · Cited by 58
Psychosocial implications of rare genetic skin diseases affecting appearance on daily life experiences, emotional state, self-perception and quality of life in adults: a systematic review
Fournier, H., Calcagni, N., Morice‐Picard, F., & Quintard, B. (2023) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-023-02629-1 · Cited by 60
Association Between Psoriasis and Sexual and Erectile Dysfunction in Epidemiologic Studies
Molina‐Leyva, A., Salvador‐Rodríguez, L., Martínez‐López, A., Ruiz‐Carrascosa, J. C., & Arias‐Santiago, S. (2018) · JAMA Dermatology · doi:10.1001/jamadermatol.2018.3442 · Cited by 52
Epidemiology of mental health comorbidity in patients with psoriasis: An analysis of trends from 1986 to 2019
Liu, L., Lin, N., Yu, Y., Wang, S., Wang, J., Cai, X., Wang, C., Zhang, M., Li, X., & Li, B. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115078 · Cited by 53
Psychiatric morbidity and suicidal behaviour in psoriasis: a primary care cohort study
Parisi, R., Webb, R. T., Kleyn, C. E., Carr, M., Kapur, N., Griffiths, C. E. M., & Ashcroft, D. M. (2018) · British Journal of Dermatology · doi:10.1111/bjd.17004 · Cited by 56
Psoriasis in Taiwan: From epidemiology to new treatments
Chiu, H., Wang, T., Chen, P.-H., Hsu, S.-H., Tsai, Y., & Tsai, T. (2018) · Dermatologica Sinica · doi:10.1016/j.dsi.2018.06.001 · Cited by 51
Risk of first‐time and recurrent depression in patients with psoriasis: a population‐based cohort study
Egeberg, A., Thyssen, J. P., Wu, J. J., & Skov, L. (2018) · British Journal of Dermatology · doi:10.1111/bjd.17208 · Cited by 50
Current challenges and emerging drug delivery strategies for the treatment of psoriasis
Hoffman, M. B., Hill, D., & Feldman, S. R. (2016) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2016.1188801 · Cited by 49
Psoriasis and sport: a new ally?
Balato, N., Megna, M., Palmisano, F., Patruno, C., Napolitano, M., Scalvenzi, M., & Ayala, F. (2015) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12607 · Cited by 48
Impact and management of depression in psoriasis patients
Korman, A. M., Hill, D., Alikhan, A., & Feldman, S. R. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2016.1128894 · Cited by 48
Psoriasis and Related Disorders
Burden, A. D., & Kirby, B. (2016) · Wiley eBooks · doi:10.1002/9781118441213.rtd0036 · Cited by 47
Neurological and psychiatric disorders in psoriasis
Amanat, M., Salehi, M., & Rezaei, N. (2018) · Reviews in the Neurosciences · doi:10.1515/revneuro-2017-0108 · Cited by 47
Prevalence and Odds of Anxiety Disorders and Anxiety Symptoms in Children and Adults with Psoriasis: Systematic Review and Meta-analysi
Jalenques, I., Bourlot, F., Martinez, E., Pereira, B., D'Incan, M., Lauron, S., & Rondepierre, F. (2022) · Acta Dermato Venereologica · doi:10.2340/actadv.v102.1386 · Cited by 45
Depression and anxiety among patients with psoriasis: A correlation with quality of life and associated factors
Bakar, R. S., Jaapar, S. Z. S., Azmi, A. F., & Aun, Y. C. (2021) · Journal of Taibah University Medical Sciences · doi:10.1016/j.jtumed.2021.02.008 · Cited by 45
Impact of Depression on Risk of Myocardial Infarction, Stroke and Cardiovascular Death in Patients with Psoriasis: A Danish Nationwide Study
Egeberg, A., Khalid, U., Gislason, G., Mallbris, L., Skov, L., & Hansen, P. R. (2015) · Acta Dermato Venereologica · doi:10.2340/00015555-2218 · Cited by 44
Psychiatric disorders associated with some chronic dermatologic diseases among a group of Egyptian dermatology outpatient clinic attendants
Sorour, F. A., Abdelmoaty, A. A., Bahary, M. H., & Birqdar, B. E. (2017) · Journal of the Egyptian Womenʼs Dermatologic Society · doi:10.1097/01.ewx.0000503397.22746.bd · Cited by 43
Management of the psychological comorbidities of dermatological conditions: practitioners' guidelines
Connor, C. J. (2017) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s111041 · Cited by 48
Psoriasis and Mental Health Workshop Report: Exploring the Links between Psychosocial Factors, Psoriasis, Neuroinflammation and Cardiovascular Disease Risk
Kleyn, C. E., Talbot, P. S., Mehta, N. N., Sampogna, F., Bundy, C., Ashcroft, D. M., Kimball, A. B., Kerkhof, P., Griffiths, C. E. M., Valenzuela, F., et al. (2019) · Acta Dermato Venereologica · doi:10.2340/00015555-3375 · Cited by 46
Comorbidities in Patients with Psoriatic Arthritis
Haddad, A., & Zisman, D. (2017) · Rambam Maimonides Medical Journal · doi:10.5041/rmmj.10279 · Cited by 42
Effectiveness of Biologic and Conventional Systemic Therapies in Adults with Chronic Plaque Psoriasis in Daily Practice: A Systematic Review
Zweegers, J., Otero, M., van den Reek, J. M. P. A., van Lümig, P. P. M., Driessen, R. S., Kievit, W., Seyger, M. M. B., van de Kerkhof, P. C. M., & de Jong, E. M. G. J. (2015) · Acta Dermato Venereologica · doi:10.2340/00015555-2276 · Cited by 41
A Novel E3 Probiotics Formula Restored Gut Dysbiosis and Remodelled Gut Microbial Network and Microbiome Dysbiosis Index (MDI) in Southern Chinese Adult Psoriasis Patients
Choy, C. T., Chan, U. K., Siu, P. L. K., Zhou, J., Wong, C. H., Lee, Y. W., Chan, H. W., Tsui, J. C. C., Loo, S. K. F., & Tsui, S. K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076571 · Cited by 39
The Prevalence of Anxiety and Depression in Arab Dermatology Patients
AlShahwan, M. A. (2015) · Journal of Cutaneous Medicine and Surgery · doi:10.2310/7750.2014.14110 · Cited by 38
Psoriatic arthritis: complexities, comorbidities and implications for the clinic
Haroon, M., & FitzGerald, O. (2016) · Expert Review of Clinical Immunology · doi:10.1586/1744666x.2016.1139453 · Cited by 38
A Chinese cross-sectional study on depression and anxiety symptoms in patients with psoriasis vulgaris
Tian, Z. F., Huang, Y., Yue, T., Zhou, J., Tao, L., Han, L., Yan, K., Huang, Q., Zhang, Z., & Shao, C. (2018) · Psychology Health & Medicine · doi:10.1080/13548506.2018.1529323 · Cited by 38
Happiness and depression in psoriasis: a cross-sectional study in Germany
Schuster, B., Peifer, C., Ziehfreund, S., Tizek, L., Biedermann, T., Zink, A., & Schielein, M. C. (2021) · Quality of Life Research · doi:10.1007/s11136-021-02991-2 · Cited by 38
The Relationship between Alexithymia and Mental Health Is Fully Mediated by Anxiety and Depression in Patients with Psoriasis
Quinto, R. M., Vincenzo, F. D., Graceffa, D., Bonifati, C., Innamorati, M., & Iani, L. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063649 · Cited by 38
Komorbidität bei Psoriasis vulgaris
Gerdes, S., Mrowietz, U., & Boehncke, W. (2016) · Der Hautarzt · doi:10.1007/s00105-016-3805-3 · Cited by 38

Authors: Dowlatshahi, E. A., Wakkee, M., Arends, L. R., & Nijsten, T.
Affiliations: Erasmus MC (NL)
Corresponding author: Nijsten, Tamar
ORCID: Wakkee, Marlies
Arends, Lidia R.
Nijsten, Tamar
Venue: Journal of Investigative Dermatology
Publisher: Elsevier BV
Published: 2014-06
Volume: 134
Issue: 6
Pages: 1542-1551
ISSN: 0022-202X (ISSN-L)
DOI: 10.1038/jid.2013.508
OpenAlex: W2005241673
Cited by: 436
References: 77
Citations by year: 2026: 33 · 2025: 41 · 2024: 33 · 2023: 40 · 2022: 30 · 2021: 47 · 2020: 41 · 2019: 37 · 2018: 46 · 2017: 31 · 2016: 29 · 2015: 16 · 2014: 9
FWCI: 1.57
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 549 d)
Locations: Journal of Investigative Dermatology (publishedVersion)
PubMed (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords: psoriasis, depression, depressive symptoms, prevalence, antidepressant use, psychiatric comorbidity, tertiary care hospital patients
MeSH terms: Antidepressive Agents, Depression, Humans, Psoriasis, Quality of Life, Surveys and Questionnaires, Risk Factors, Prevalence, Confidence Intervals, Odds Ratio

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Prevalence and Odds of Depressive Symptoms and Clinical Depression in Psoriasis Patients: A Systematic Review and Meta-Analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks