The DOI matches its Crossref record; 73 of the 77 references it cites were found in a registry or an index.
The Prevalence and Odds of Depressive Symptoms and Clinical Depression in Psoriasis Patients: A Systematic Review and Meta-Analysis
Open accessAbstract
The reported prevalence of depression in psoriasis varies substantially. This study aims to determine the prevalence and odds of depressive symptoms and clinical depression in psoriasis. A systematic literature search was conducted. Mean questionnaire values and proportions for depressive symptoms and clinical depression were pooled according to different assessment methods. In controlled studies, standardized mean differences (SMDs) and odds ratio (OR) compared depression in psoriasis patients with controls using the random-effect model. The majority of the 98 eligible studies were conducted in tertiary centers without a control group. The prevalence of depressive symptoms was 28% using questionnaires and the prevalence of clinical depression was 12% using International Classification of Diseases codes, 19% using Diagnostic and Statistical Manual of Mental Disorders IV, and 9% for antidepressant use. Psoriasis patients had significantly more depressive symptoms (SMD 1.16; 95% confidence interval (CI) 0.67-1.66), and population-based studies showed that they were at least one and a half times more likely to experience depression (OR 1.57; 95% CI 1.40-1.76) and used more antidepressants than did controls (OR 4.24, 95% CI 1.53-11.76). More than 10% of psoriasis patients suffer from clinical depression, and twice as many have depressive symptoms. The high prevalence of these symptoms is likely to be affected by the tertiary study populations and differential misclassification using questionnaires, where psoriasis-related symptoms may be detected as depressive symptoms.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The prevalence of depression among psoriasis patients and the significant OR of 3.02 are in accordance with a recent meta-analysis of 98 studies, showing that >10% of psoriasis patients have clinical depression (Dowlatshahi et al., 2013).”
From The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries (2015) · cites this paper as Dowlatshahi et al., 2013
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763
(1992) · PubMed · Cited by 33,716
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gotzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · BMJ · doi:10.1136/bmj.b2700 · Cited by 17,648
(2014) · Medical Entomology and Zoology · Cited by 17,633
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962
Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation
Beck, A. T., Steer, R. A., & Carbin, M. G. (1988) · Clinical Psychology Review · doi:10.1016/0272-7358(88)90050-5 · Cited by 11,696
(1998) · PubMed · Cited by 10,216
A self-rating depression scale
ZUNG, W. W. K. (1965) · Archives of General Psychiatry · doi:10.1001/archpsyc.1965.01720310065008 · Cited by 9,813
The validity of the Hospital Anxiety and Depression Scale
Bjelland, I., Dahl, A. A., Haug, T. T., & Neckelmann, D. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(01)00296-3 · Cited by 9,779 · cited 1×
“, 1997), HADS (Zigmond and Snaith, 1983; Bjelland et al., 2002), Hamilton DS (Hamilton, 1960), CRSD (Carroll et al.”
MCHORNEY, C. A., JOHNE, W., & ANASTASIAE, R. (1993) · Medical Care · doi:10.1097/00005650-199303000-00006 · Cited by 6,681
The mini international neuropsychiatric interview
Lecrubier, Y., Sheehan, D. V., Hergueta, T., & Weiller, E. (1998) · European Psychiatry · doi:10.1016/s0924-9338(99)80239-9 · Cited by 5,899
The Prevalence of Comorbid Depression in Adults With Diabetes
Anderson, R. J., Freedland, K. E., Clouse, R. E., & Lustman, P. J. (2001) · Diabetes Care · doi:10.2337/diacare.24.6.1069 · Cited by 3,926
Diagnostic and Statistical Manual of Mental Disorders
Sciacca, F., Sharma, R., & Knipe, H. (2020) · Radiopaedia.org · doi:10.53347/rid-80880 · Cited by 2,395
Rutledge, T., Reis, V. A., Linke, S. E., Greenberg, B. H., & Mills, P. J. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.06.055 · Cited by 1,513
Psoriasis causes as much disability as other major medical diseases
Rapp, S. R., Feldman, S. R., Exum, M. L., Fleischer, A. B., & Reboussin, D. M. (1999) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(99)70112-x · Cited by 1,489
Beekman, A. T. F., Deeg, D. J. H., van Limbeek, J., Braam, A. W., VRIES, M. Z. D., & van Tilburg, W. (1997) · Psychological Medicine · doi:10.1017/s0033291796003510 · Cited by 1,135
Pignone, M. P., Gaynes, B. N., Rushton, J. L., Burchell, C. M., Orleans, C. T., Mulrow, C. D., & Lohr, K. N. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-10-200205210-00013 · Cited by 1,086
Palmer, S., Vecchio, M., Craig, J. C., Tonelli, M., Johnson, D. W., Nicolucci, A., Pellegrini, F., Saglimbene, V., Logroscino, G., Fishbane, S., et al. (2013) · Kidney International · doi:10.1038/ki.2013.77 · Cited by 925
for the European Depression in Diabetes (EDID) Research Consortium, Nouwen, A., Winkley, K., Twisk, J., Lloyd, C. E., Peyrot, M., Ismail, K., & Pouwer, F. (2010) · Diabetologia · doi:10.1007/s00125-010-1874-x · Cited by 756
Stern, R. S., Nijsten, T. E. C., Feldman, S. R., Margolis, D. J., & Rolstad, T. (2004) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1046/j.1087-0024.2003.09102.x · Cited by 732
Self-citationThe Risk of Depression, Anxiety, and Suicidality in Patients With Psoriasis
Chosidow, O., ROBERT, P. D., DAIHUNG, D., URBÀ, G., CATALIN, M. P., Hywel, W., Kurd, S. K., Troxel, A. B., Crits-Christoph, P. F., & Gelfand, J. M. (2010) · Archives of Dermatology · doi:10.1001/archdermatol.2010.186 · Cited by 646
Depression in Rheumatoid Arthritis: A Systematic Review of the Literature With Meta-Analysis
Dickens, C. M., McGowan, L., Clark-Carter, D. D., & Creed, F. H. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200201000-00008 · Cited by 635
Langan, S., Seminara, N. M., Shin, D. B., Troxel, A. B., Kimmel, S. E., Mehta, N. N., Margolis, D. J., & Gelfand, J. M. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.365 · Cited by 523
The Carroll Rating Scale for Depression I. Development, Reliability and Validation
Carroll, B. J., Feinberg, M. P., Smouse, P. E., Rawson, S. G., & Greden, J. F. (1981) · The British Journal of Psychiatry · doi:10.1192/bjp.138.3.194 · Cited by 380
Gupta, A. K., Gupta, A. K., Schork, N. J., & Ellis, C. N. (1994) · Psychosomatic Medicine · doi:10.1097/00006842-199401000-00005 · Cited by 328
Epidemiology and comorbidities of psoriasis patients in a national database in Taiwan
Tsai, T., Wang, T., Hung, S.-T., Tsai, P. I.-C., Schenkel, B., Zhang, M., & Tang, C. (2011) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2011.03.002 · Cited by 323
Is This Patient Clinically Depressed?
Williams, J. W. (2002) · JAMA · doi:10.1001/jama.287.9.1160 · Cited by 319
The contribution of perceptions of stigmatisation to disability in patients with psoriasis
Richards, H. L., Fortune, D. G., Griffiths, C. E. M., & Main, C. J. (2001) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(00)00210-5 · Cited by 295
SUICIDAL IDEATION IN PSORIASIS
Gupta, M. A., Schork, N. J., Gupta, A. K., Kirkby, S., & Ellis, C. N. (1993) · International Journal of Dermatology · doi:10.1111/j.1365-4362.1993.tb02790.x · Cited by 262
A cognitive-behavioural symptom management programme as an adjunct in psoriasis therapy
Fortune, D. G., Richards, H. L., Kirby, B., Bowcock, S., Main, C. J., & Griffiths, C. E. M. (2002) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2002.04622.x · Cited by 254
An Italian Study on Psoriasis and Depression
Esposito, M., Saraceno, R., Giunta, A., Maccarone, M., & Chimenti, S. (2006) · Dermatology · doi:10.1159/000090652 · Cited by 249
Psychological Distress Impairs Clearance of Psoriasis in Patients Treated With Photochemotherapy
Fortune, D. G., Richards, H. L., Kirby, B., McElhone, K., Markham, T., Rogers, S., Main, C. J., & Griffiths, C. E. M. (2003) · Archives of Dermatology · doi:10.1001/archderm.139.6.752 · Cited by 244
Fortune, D. G., Richards, H. L., Griffiths, C. E. M., & Main, C. J. (2002) · British Journal of Clinical Psychology · doi:10.1348/014466502163949 · Cited by 240
Screening and case finding instruments for depression
Gilbody, S., House, A., & Sheldon, T. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002792.pub2 · Cited by 205
the BELLA study group, Döpfner, M., Breuer, D., Wille, N., Erhart, M., & Ravens‐Sieberer, U. (2008) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-008-1007-y · Cited by 196
Sampogna, F., Sera, F., & ABENI, D. D. (2004) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2003.09101.x · Cited by 191
Psoriasis and sex: a study of moderately to severely affected patients
Gupta, M. A., & Gupta, A. K. (1997) · International Journal of Dermatology · doi:10.1046/j.1365-4362.1997.00032.x · Cited by 183
Role of Depression in Quality of Life for Patients with Psoriasis
Schmitt, J. M., & Ford, D. E. (2007) · Dermatology · doi:10.1159/000102029 · Cited by 167
de Korte, J., Mombers, F. M. C., Sprangers, M., & Bos, J. (2002) · Archives of Dermatology · doi:10.1001/archderm.138.9.1221 · Cited by 167
Gupta, M. A. (1988) · Archives of Dermatology · doi:10.1001/archderm.1988.01670070040016 · Cited by 154
Psychiatric Morbidity in Psoriasis and Vitiligo: A Comparative Study
Sharma, N., Koranne, R. V., & Singh, R. K. (2001) · The Journal of Dermatology · doi:10.1111/j.1346-8138.2001.tb00003.x · Cited by 149
Classification in psychiatry: ICD–10 versus DSM–IV
Andrews, G., Slade, T., & Peters, L. (1999) · British Journal of Psychiatry · doi:10.1192/bjp.174.1.3 · Cited by 145
Schmitt, J. M., & Ford, D. (2009) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2009.03537.x · Cited by 133
Use of the general health questionnaire in clinical work.
Goldberg, D. P. (1986) · BMJ · doi:10.1136/bmj.293.6556.1188 · Cited by 128
Richards, H. L., Fortune, D. G., Weidmann, A. K., Sweeney, S. K. T., & Griffiths, C. E. M. (2004) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2004.06221.x · Cited by 123
Economic burden of comorbidities in patients with psoriasis is substantial
Kimball, A. B., Guérin, A., Tsaneva, M., Yu, A., Wu, E., Gupta, S., Bao, Y., & Mulani, P. M. (2010) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2010.03730.x · Cited by 122
Gupta, M. A., Gupta, A. K., & Watteel, G. N. (1998) · PubMed · Cited by 104
Sexual dysfunction in patients with psoriasis
Ermertcan, A. T., Temeltaş, G., Deveci, A., Dinç, G., GÜLER, H. B., & Öztürkcan, S. (2006) · The Journal of Dermatology · doi:10.1111/j.1346-8138.2006.00179.x · Cited by 101
The Carroll Rating Scale for Depression
Feinberg, M. P., & Carroll, B. J. (1986) · Springer eBooks · doi:10.1007/978-3-642-70486-4_18 · Cited by 97
Schmitt, J. M., & Ford, D. E. (2007) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2006.12.004 · Cited by 94
Depression and Anxiety Disorders among Patients with Psoriasis: A Hospital-Based Case-Control Study
Golpour, M., Hosseini, S. H., Khademloo, M., Ghasemi, M., Ebadi, A., Koohkan, F., & Shahmohammadi, S. (2012) · Dermatology Research and Practice · doi:10.1155/2012/381905 · Cited by 85
Han, C., Lofland, J. H., Zhao, N. O., & Schenkel, B. (2011) · PubMed · Cited by 73
Divergent Beliefs About Psoriasis Are Associated with Increased Psychological Distress
Richards, H. L., Fortune, D. G., Chong, S. L. P., Mason, D., Sweeney, S. K. T., Main, C. J., & Griffiths, C. E. M. (2004) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2004.22703.x · Cited by 63
Li, W., Han, J., Hu, F. B., Curhan, G. C., & Qureshi, A. A. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.319 · Cited by 62
Attentional Bias for Psoriasis-Specific and Psychosocial Threat in Patients with Psoriasis
Fortune, D. G., Richards, H. L., Corrin, A. R., Taylor, R. J., Griffiths, C. E. M., & Main, C. J. (2003) · Journal of Behavioral Medicine · doi:10.1023/a:1023408503807 · Cited by 56
Quality of Life Impairment and Psychological Distress in Elderly Patients with Psoriasis
Sampogna, F., Tabolli, S., Mastroeni, S., Pietro, C. D., Fortes, C., & ABENI, D. D. (2007) · Dermatology · doi:10.1159/000107628 · Cited by 53
Crown, W. H., Bresnahan, B. W., Orsini, L. S., Kennedy, S., & Leonardi, C. L. (2004) · Current Medical Research and Opinion · doi:10.1185/030079904x15192 · Cited by 53
Saito, M., Iwata, N., Kawakami, N., Matsuyama, Y., Ono, Y., Nakane, Y., Nakamura, Y., Tachimori, H., Uda, H., Nakane, H., et al. (2010) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.320 · Cited by 41
Fortune, D. G., Richards, H. L., Griffiths, C. E. M., & Main, C. J. (2004) · Psychology Health & Medicine · doi:10.1080/13548500512331315352 · Cited by 32
Psoriasis, mental disorders and stress.
Biljan, D., Laufer, D., Filaković, P., Šitum, M., & Brataljenović, T. (2009) · PubMed · Cited by 30
Pruritus associated with nocturnal wakenings: Organic or psychogenic?
Gupta, M. A., Gupta, A. K., Kirkby, S., Schork, N. J., Weiner, H. K., Ellis, C. N., & Voorhees, J. J. (1989) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(89)70211-5 · Cited by 29
The Carroll Rating Scale for Depression II. Factor Analyses of the Feature Profiles
Smouse, P. E., Feinberg, M. P., Carroll, B. J., Park, M. H., & Rawson, S. G. (1981) · The British Journal of Psychiatry · doi:10.1192/bjp.138.3.201 · Cited by 24
Dowlatshahi, E. A., Wakkee, M., Herings, R. M. C., Hollestein, L. M., & Nijsten, T. E. C. (2013) · Acta Dermato Venereologica · doi:10.2340/00015555-1566 · Cited by 24
Self-citationSymptoms of Depression and Anxiety, and Screening for Mental Disorders in Migrainous Patients
Kowacs, F., Socal, M., Ziomkowski, S., Borges-Neto, V., Toniolo, D. P., Francesconi, C., & Chaves, M. (2003) · Cephalalgia · doi:10.1046/j.1468-2982.2003.00461.x · Cited by 21
Fortune, D. G., Richards, H. L., Griffiths, C. E. M., & Main, C. J. (2005) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-005-3274-9 · Cited by 13
Research works printed but not linked: 3
- Chan, 2009, Depression in Hong Kong Chinese patients with psoriasis, Hong Kong J Dermatol Venereol, 17, 69
- Dowlatshahi, 2011, Antidepressant drug use in patients with psoriasis: a population based cohort study, J Invest Dermatol, 131, S48
- Zhang, 2011, Prevalence of autoimmune diseases and other comorbidities in patients with psoriatic arthritis in the United States, Arthritis Care Res, 63, 1333
Cited by
Sorted by citations
Pathophysiology, Clinical Presentation, and Treatment of Psoriasis
Armstrong, A. W., & Read, C. (2020) · JAMA · doi:10.1001/jama.2020.4006 · Cited by 2,364
Psoriasis and comorbid diseases
Takeshita, J., Grewal, S. K., Langan, S., Mehta, N. N., Ogdie, A., Voorhees, A. S. V., & Gelfand, J. M. (2017) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2016.07.064 · Cited by 1,228
Dalgard, F. J., Gieler, U., Tomas-Aragones, L., Lien, L., Poot, F., Jemec, G. B. E., Misery, L., Szabo, C., Linder, D., Sampogna, F., et al. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.530 · Cited by 968
Comorbid depression in medical diseases
Gold, S. M., Köhler‐Forsberg, O., Moss-Morris, R. E., Mehnert-Theuerkauf, A., Miranda, J. J., Bullinger, M., Steptoe, A., Whooley, M. A., & Otte, C. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0200-2 · Cited by 583
Elmets, C. A., Leonardi, C. L., Davis, D. M. R., Gelfand, J. M., Lichten, J. B., Mehta, N. N., Armstrong, A. W., Connor, C. J., Cordoro, K. M., Elewski, B. E., et al. (2019) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2018.11.058 · Cited by 542
Metadata
- Authors
- Dowlatshahi, E. A., Wakkee, M., Arends, L. R., & Nijsten, T.
- Affiliations
- Erasmus MC (NL)
- Corresponding author
- Nijsten, Tamar
- Venue
- Journal of Investigative Dermatology
- Publisher
- Elsevier BV
- Published
- 2014-06
- Volume
- 134
- Issue
- 6
- Pages
- 1542-1551
- ISSN
- 0022-202X (ISSN-L)
- OpenAlex
- W2005241673
- Cited by
- 436
- References
- 77
- Citations by year
- 2026: 33 · 2025: 41 · 2024: 33 · 2023: 40 · 2022: 30 · 2021: 47 · 2020: 41 · 2019: 37 · 2018: 46 · 2017: 31 · 2016: 29 · 2015: 16 · 2014: 9
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Investigative Dermatology (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- psoriasis, depression, depressive symptoms, prevalence, antidepressant use, psychiatric comorbidity, tertiary care hospital patients
- MeSH terms
- Antidepressive Agents, Depression, Humans, Psoriasis, Quality of Life, Surveys and Questionnaires, Risk Factors, Prevalence, Confidence Intervals, Odds Ratio
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review