Cited by 134Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental DisordersGenetic Associations and Epidemiology

Autism recurrence in half siblings: strong support for genetic mechanisms of transmission in ASD

Constantino, J N, Todorov, A, Hilton, C, Law, P, Zhang, Y, Molloy, E, Fitzgerald, R, Geschwind, D·2013·Molecular Psychiatry

Integrity signals

Registry

Crossref · 10.1038/mp.2012.9

Cites

8 of 8 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Only few earlier studies have had the possibility to calculate the relative recurrence risk.

    “Only few earlier studies have had the possibility to calculate the RR8,27,28.”

    From The Familial Risk of Autism (2014) · cites this paper as [8]

  • Two earlier studies presented self-selected samples and limited family data.

    “Two studies are presenting self-selected samples8,28 and with limited family data.”

    From The Familial Risk of Autism (2014) · cites this paper as [8]

  • The overrepresentation of high-risk siblings in latent classes with subtly disturbed functioning is consonant with genetic models of autism spectrum disorder that encompass transmission of subclinical manifestations in a subset of first-degree relatives.

    “The overrepresentation of HR siblings among latent classes characterized by subtly disturbed levels of functioning is consonant with genetic models of ASD that encompass the transmission of subclinical manifestations of the autistic syndrome in a subset of first-degree relatives, on the basis of either incomplete penetrance or additive (multigenic) models of inheritance.39–41”
  • Earlier population studies indicated importance of shared maternal bloodline in sibling risk.

    “Earlier population studies have indicated the importance of a shared maternal bloodline in sibling risk (19,20).”
  • Enhanced anandamide signaling can curb the effects of chronic stress, possibly by maintaining normal amygdala function via extinction-driven reductions in fear resulting in improved stress-reactivity in humans.

    “as emerging data have revealed that enhanced anandamide signaling can curb the effects of chronic stress, possibly by maintaining normal amygdala function64 via extinction-driven reductions in fear resulting in improved stress-reactivity in humans10.”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Constantino, J. N., Todorov, A., Hilton, C., Law, P., Zhang, Y., Molloy, E., Fitzgerald, R., & Geschwind, D.
Affiliations
  • Washington University in St. Louis (US)
  • Kennedy Krieger Institute (US)
  • University of California, Los Angeles (US)
Corresponding author
Constantino, J N
Venue
Molecular Psychiatry
Published
2012-02-28
Volume
18
Issue
2
Pages
137-138
ISSN
  • 1359-4184 (ISSN-L)
  • 1476-5578
OpenAlex
W2069515082
Cited by
134
References
8
Citations by year
2026: 2 · 2025: 3 · 2024: 1 · 2023: 4 · 2022: 9 · 2021: 8 · 2020: 12 · 2019: 11 · 2018: 11 · 2017: 8 · 2016: 16 · 2015: 20 · 2014: 14 · 2013: 9 · 2012: 6
FWCI
8.03
Type
journal article
Language
en
Open access
closed
Locations
  • Molecular Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Autism Speaks (AS2306)
  • National Institute of Neurological Disorders and Stroke (R01NS073871)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords
autism spectrum disorder, half-siblings, genetic transmission, heritability, genetic susceptibility, pleiotropy, maternal genetics, fetal brain development
MeSH terms
Adolescent, Autistic Disorder, Child, Child Development Disorders, Pervasive, Child, Preschool, Female, Humans, Male, Recurrence, Registries, Prevalence, Siblings

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review