The immunopathogenesis of sepsis

Early goal-directed therapy in the treatment of severe sepsis and septic shock

Rivers, E., Nguyen, B., Havstad, S., Ressler, J., Muzzin, A., Knoblich, B., Peterson, E., & Tomlanovich, M. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010307 · Cited by 10,743

Intensive insulin therapy in critically ill patients.

Van den Berghe, G., Wouters, P., Weekers, F., Verwaest, C., Bruyninckx, F., Schetz, M., Vlasselaers, D., Ferdinande, P., Lauwers, P., & Bouillon, R. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011300 · Cited by 9,977

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

Angus, D. C., Linde-Zwirble, W. T., Lidicker, J., Clermont, G., Carcillo, J., & Pinsky, M. R. (2001) · Critical Care Medicine · doi:10.1097/00003246-200107000-00002 · Cited by 8,503

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Medzhitov, R., Preston-Hurlburt, P., & Janeway, C. A. J. (1997) · Nature · doi:10.1038/41131 · Cited by 6,137

Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

Bernard, G. R., Vincent, J., Laterre, P., LaRosa, S. P., Dhainaut, J.-F., Lopez-Rodriguez, A., Steingrub, J. S., Garber, G. E., Helterbrand, J. D., Ely, E. W., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200103083441001 · Cited by 6,124

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

Wright, S. D., Ramos, R., Tobias, P. S., Ulevitch, R. J., & Mathison, J. C. (1990) · Science · doi:10.1126/science.1698311 · Cited by 3,996

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K., & Akira, S. (1999) · Immunity · doi:10.1016/s1074-7613(00)80119-3 · Cited by 3,680

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Hayashi, F., Smith, K. D., Ozinsky, A., Hawn, T. R., Yi, E. C., Goodlett, D. R., Eng, J. K., Akira, S., Underhill, D. M., & Aderem, A. A. (2001) · Nature · doi:10.1038/35074106 · Cited by 3,605

HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Wang, H., Bloom, O., Zhang, M., Vishnubhakat, J. M., Ombrellino, M., Che, J., Frazier, A., Yang, H., Ivanova, S., Borovikova, L. V., et al. (1999) · Science · doi:10.1126/science.285.5425.248 · Cited by 3,386

Immunomodulatory activity of protein hydrolysates derived from Virgibacillus halodenitrificans SK1-3-7 proteinase

Tidarat, T., Mes, J. J., Wichers, H. J., & Yongsawatdigul, J. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.12.041 · Cited by 41

6-Nitrotriazolo[1,5-a]pyrimidines as promising structures for pharmacotherapy of septic conditions

Savateev, K. V., Ulomsky, E. N., Fedotov, V. V., Русинов, В. Л., Сивак, К. В., Любишин, М. М., Kuzmich, N. N., & Александров, А. Г. (2017) · Russian Journal of Bioorganic Chemistry · doi:10.1134/s1068162017040094 · Cited by 41

An Essential Role for TAGLN2 in Phagocytosis of Lipopolysaccharide-activated Macrophages

Kim, H. R., Lee, H., Lee, K.-S., Jung, I. D., Kwon, M., Kim, C., Kim, S., Yoon, M., Park, Y., Lee, S., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-09144-x · Cited by 41

Thymoquinone reduces mortality and suppresses early acute inflammatory markers of sepsis in a mouse model

Alkharfy, K. M., Ahmad, A., Jan, B. L., & Raish, M. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.01.028 · Cited by 41

Mitochondrial Division Inhibitor 1 Attenuates Mitophagy in a Rat Model of Acute Lung Injury

Luo, X., Liu, R., Zhang, Z., Chen, Z., He, J., & Liu, Y. (2019) · BioMed Research International · doi:10.1155/2019/2193706 · Cited by 41

Artesunate interacts with the vitamin D receptor to reverse sepsis‐induced immunosuppression in a mouse model via enhancing autophagy

Shang, S., Wu, J., Li, X., Liu, X., Pan, L., Zheng, C., Wang, Y., Liu, S., Zheng, J., & Zhou, H. (2020) · British Journal of Pharmacology · doi:10.1111/bph.15158 · Cited by 41

A Novel Peptide Antibiotic, Pro10-1D, Designed from Insect Defensin Shows Antibacterial and Anti-Inflammatory Activities in Sepsis Models

Krishnan, M., Choi, J., Jang, A., & Kim, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176216 · Cited by 41

Dissecting the relationship between antimicrobial peptides and mesenchymal stem cells

Silva-Carvalho, A. É., Cardoso, M. H. E. S., Alencar‐Silva, T., Bogéa, G. M. R., Carvalho, J. L., Franco, O. L., & Saldanha‐Araújo, F. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.108021 · Cited by 41

The Acyl Group as the Central Element of the Structural Organization of Antimicrobial Lipopeptide

Japelj, B., Zorko, M. S., Majerle, A., Pristovšek, P., Sánchez-Gómez, S., de Tejada, G. M., Moriyón, I., Blondelle, S. E., Brandenburg, K., Andrä, J., et al. (2007) · Journal of the American Chemical Society · doi:10.1021/ja067419v · Cited by 41

Induction of cystine/glutamate transporter in bacterial lipopolysaccharide induced endotoxemia in mice

Taguchi, K., Tamba, M., Bannai, S., & Sato, H. (2007) · Journal of Inflammation · doi:10.1186/1476-9255-4-20 · Cited by 41

Lysophospholipid metabolism facilitates Toll-like receptor 4 membrane translocation to regulate the inflammatory response

Jackson, S. K., Abate, W., Parton, J., Jones, S., & Harwood, J. L. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.0907601 · Cited by 41

SYNCRIP-Dependent Nox2 mRNA Destabilization Impairs ROS Formation in M2-Polarized Macrophages

Kuchler, L., Giegerich, A. K., Sha, L. K., Knape, T., Wong, M. S. K., Schröder, K., Brandes, R. P., Heide, H., Wittig, I., Brüne, B., et al. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5760 · Cited by 40

Purified active lotus plumule (Nelumbo nucifera Gaertn) polysaccharides exert anti-inflammatory activity through decreasing Toll-like receptor-2 and -4 expressions using mouse primary splenocytes

Liao, C.-H., & Lin, J. (2013) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2013.02.028 · Cited by 40

Peptide Nanofibers Preconditioned with Stem Cell Secretome Are Renoprotective

Wang, Y., Bakota, E. L., Chang, B. H., Entman, M. L., Hartgerink, J. D., & Danesh, F. R. (2011) · Journal of the American Society of Nephrology · doi:10.1681/asn.2010040403 · Cited by 40

Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction

Yin, Y., Xu, N., Shi, Y., Zhou, B., Sun, D., Ma, B., Xu, Z., Yang, J., & Li, C. (2021) · Marine Drugs · doi:10.3390/md19060346 · Cited by 40

Flow cytometric analysis of peripheral blood dendritic cells in patients with severe sepsis

Riccardi, F., Porta, M. G. D., Rovati, B., Casazza, A., Radolovich, D. K., AMICI, M. D., Danova, M., & Langer, M. (2010) · Cytometry Part B Clinical Cytometry · doi:10.1002/cyto.b.20540 · Cited by 40

Characterization of the LPS-induced inflammation of the adrenal gland in mice

Kanczkowski, W., Chatzigeorgiou, A., Samus, M., Tran, N., Zacharowski, K. D., Chavakis, T., & Bornstein, S. R. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.12.020 · Cited by 40

Methyl palmitate inhibits lipopolysaccharide‐stimulated phagocytic activity of rat peritoneal macrophages

Sarkar, S., Khan, M. F., Kaphalia, B. S., & Ansari, G. A. S. (2006) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.20150 · Cited by 40

Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis

Li, P., Guo, Y., Bledsoe, G., Yang, Z., Fan, H., Chao, L., & Chao, J. (2015) · Critical Care · doi:10.1186/s13054-015-0919-4 · Cited by 39

Agarose-Based Microfluidic Device for Point-of-Care Concentration and Detection of Pathogen

Li, Y., Yan, X., Feng, X., Wang, J., Du, W., Wang, Y., Chen, P., Xiong, L., & Liu, B. (2014) · Analytical Chemistry · doi:10.1021/ac5026623 · Cited by 39

The SaeR/S Gene Regulatory System Induces a Pro-Inflammatory Cytokine Response during Staphylococcus aureus Infection

Watkins, R. L., Pallister, K. B., & Voyich, J. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019939 · Cited by 39

N-glycosylation deficiency reduces ICAM-1 induction and impairs inflammatory response

He, P., Srikrishna, G., & Freeze, H. H. (2014) · Glycobiology · doi:10.1093/glycob/cwu006 · Cited by 39

A Conjugated Linoleic Acid-Enriched Beef Diet Attenuates Lipopolysaccharide-Induced Inflammation in Mice in Part through PPARγ-Mediated Suppression of Toll-Like Receptor 4

Reynolds, C. M., Draper, E., Keogh, B., Rahman, A., MOLONEY, A. P., Mills, K. H. G., Loscher, C. E., & Roche, H. M. (2009) · Journal of Nutrition · doi:10.3945/jn.109.113035 · Cited by 39

Anti-inflammatory effects of vicenin-2 and scolymoside in vitro and in vivo

Kang, H., Ku, S., Jung, B., & Bae, J. (2015) · Inflammation Research · doi:10.1007/s00011-015-0886-x · Cited by 39

Monitoring sepsis using electrical cell profiling

Prieto, J. L., Su, H.-W., Hou, H. W., Pinilla-Vera, M., Levy, B. D., Baron, R. M., Han, J., & Joel Voldman, B. (2016) · Lab on a Chip · doi:10.1039/c6lc00940a · Cited by 39

Innovative Drugs to Target Renal Inflammation in Sepsis: Alkaline Phosphatase

Hümmeke-Oppers, F., Hemelaar, P., & Pickkers, P. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00919 · Cited by 39

Aggregated carbon dots‐loaded macrophages treat sepsis by eliminating multidrug‐resistant bacteria and attenuating inflammation

Li, L., Chen, L., Lu, Y., Li, B., Hu, R., Huang, L., Zhang, T., Wei, X., Yang, Z., & Mao, C. (2022) · Aggregate · doi:10.1002/agt2.200 · Cited by 39

Sodium-Dependent Glucose Transporter-1 as a Novel Immunological Player in the Intestinal Mucosa

Palazzo, M., Gariboldi, S., Zanobbio, L., Selleri, S., Dusio, G. F., Mauro, V., Rossini, A., Balsari, A., & Rumio, C. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.5.3126 · Cited by 41

An LRR-only protein representing a new type of pattern recognition receptor in Chlamys farreri

Wang, M., Wang, L., Guo, Y., Yi, Q., & Song, L. (2015) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2015.09.006 · Cited by 39

High serum nitric oxide levels in patients with severe leptospirosis

Maciel, E. A. P., Athanazio, D. A., Reis, E. A. G., Cunha, F. Q., Queiroz, A., de Almeida, D. T., McBride, A. J. A., Ko, A. I., & dos Reis, M. G. (2006) · Acta Tropica · doi:10.1016/j.actatropica.2006.11.006 · Cited by 39

Proinflammatory Mediators of Toxic Shock and Their Correlation to Lethality

Krakauer, T., Buckley, M. J., & Fisher, D. (2010) · Mediators of Inflammation · doi:10.1155/2010/517594 · Cited by 39

Furosemide is associated with acute kidney injury in critically ill patients

Levi, T. M., Rocha, M. D. S., Almeida, D. N., Martins, R. T. C., Silva, M. G. C., Santana, N., Sanjuan, I. T., & Cruz, C. M. S. (2012) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2012007500093 · Cited by 39

The return of the Scarlet Pimpernel: cobalamin in inflammation II — cobalamins can both selectively promote all three nitric oxide synthases (NOS), particularly iNOS and eNOS, and, as needed, selectively inhibit iNOS and nNOS

Wheatley, C. (2007) · Journal of Nutritional & Environmental Medicine · doi:10.1080/10520290701791839 · Cited by 42

β-1,4-Mannobiose Stimulates Innate Immune Responses and Induces TLR4-Dependent Activation of Mouse Macrophages but Reduces Severity of Inflammation during Endotoxemia in Mice

Kovacs-Nolan, J., Kanatani, H., Nakamura, A., Ibuki, M., & Mine, Y. (2013) · Journal of Nutrition · doi:10.3945/jn.112.167866 · Cited by 38

Anti-inflammatory effects of oroxylin A on RAW 264.7 mouse macrophages induced with polyinosinic-polycytidylic acid

Lee, J. Y., & Park, W. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3320 · Cited by 39

Annexin A5 Increases Survival in Murine Sepsis Model by Inhibiting HMGB1-Mediated Proinflammation and Coagulation

Park, J. H., Jang, J., Choi, E. J., Kim, Y. S., Lee, E. J., Jung, I. D., Han, H. D., Wu, T., Hung, C., Kang, T. H., et al. (2016) · Molecular Medicine · doi:10.2119/molmed.2016.00026 · Cited by 38

Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model

Lee, S. W., Park, H. J., Kaer, L. V., Hong, S., & Hong, S. (2018) · Scientific Reports · doi:10.1038/s41598-018-28396-9 · Cited by 38

C/EBPδ protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress

Banerjee, S., Fu, Q., Shah, S. K., Melnyk, S. B., Sterneck, E., Hauer‐Jensen, M., & Pawar, S. A. (2019) · Scientific Reports · doi:10.1038/s41598-019-49437-x · Cited by 38

Bacterial virulence plays a crucial role in MRSA sepsis

Cheung, G. Y. C., Bae, J. S., Liu, R., Hunt, R. L., Zheng, Y., & Otto, M. J. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009369 · Cited by 38

Immunological Endotyping of Chronic Critical Illness After Severe Sepsis

Fenner, B. P., Darden, D. B., Kelly, L. S., Rincon, J. C., Brakenridge, S. C., Larson, S. D., Moore, F. A., Efron, P. A., & Moldawer, L. L. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2020.616694 · Cited by 41

Dapagliflozin Ameliorates Lipopolysaccharide Related Acute Kidney Injury in Mice with Streptozotocin-induced Diabetes Mellitus

Chi, P., Lee, C., Hsieh, Y.-J., Lu, C., & Hsu, B. (2022) · International Journal of Medical Sciences · doi:10.7150/ijms.69031 · Cited by 40

Mapping residue-specific contacts of polymyxin B with lipopolysaccharide by saturation transfer difference NMR: Insights into outer-membrane disruption and endotoxin neutralization

Bhunia, A., & Bhattacharjya, S. (2010) · Biopolymers · doi:10.1002/bip.21530 · Cited by 38

Cardamonin suppresses nitric oxide production via blocking the IFN-γ/STAT pathway in endotoxin-challenged peritoneal macrophages of ICR mice

Takahashi, A., Yamamoto, N., & Murakami, A. (2011) · Life Sciences · doi:10.1016/j.lfs.2011.06.027 · Cited by 38

Alkaline Phosphatase as a Treatment of Sepsis-Associated Acute Kidney Injury

Peters, E., van Elsas, A., Heemskerk, S., Jonk, L. J. C., van der Hoeven, J., Arend, J., Masereeuw, R., & Pickkers, P. (2012) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.112.198226 · Cited by 38

Microglia from neurogenic and non-neurogenic regions display differential proliferative potential and neuroblast support

Marshall, G. P., Deleyrolle, L. P., Reynolds, B. A., Steindler, D. A., & Laywell, E. D. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00180 · Cited by 38

Cell Activation by Ligands of the Toll-Like Receptor and Interleukin-1 Receptor Family Depends on the Function of the Large-Conductance Potassium Channel MaxiK in Human Macrophages

Scheel, O., Papavlassopoulos, M., Blunck, R., Gebert, A., Härtung, T., Zähringer, U., Seydel, U., & Schromm, A. B. (2006) · Infection and Immunity · doi:10.1128/iai.01783-05 · Cited by 38

A potential therapeutic role for aldose reductase inhibitors in the treatment of endotoxin-related inflammatory diseases

Pandey, S., Sk, S., & Ramana, K. V. (2012) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2012.656198 · Cited by 38

A potent anti-inflammatory peptide from the salivary glands of horsefly

Wei, L., Huang, C., Yang, H., Li, M., Yang, J., Qiao, X., Mu, L., Xiong, F., Wu, J., & Xu, W. (2015) · Parasites & Vectors · doi:10.1186/s13071-015-1149-y · Cited by 38

Casein Kinase 2 Interacting Protein-1 regulates M1 and M2 inflammatory macrophage polarization

Chen, Y., Liu, W., Wang, Y., Zhang, L., Wei, J., Zhang, X., He, F., & Zhang, L. (2017) · Cellular Signalling · doi:10.1016/j.cellsig.2017.02.015 · Cited by 38

Strategic Targets of Essential Host-Pathogen Interactions

Blasi, F., Tarsia, P., & Aliberti, S. (2005) · Respiration · doi:10.1159/000083394 · Cited by 39

Nephroprotective effect of apilarnil in lipopolysaccharide-induced sepsis through TLR4/NF-κB signaling pathway

İnandıklıoğlu, N., Doğanyiğit, Z., Okan, A., Kaymak, E., & Sılıcı, S. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119875 · Cited by 37

L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization

Kang, L., Pang, J., Zhang, X., Liu, Y., Wu, Y., Wang, J., & Han, D. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.09.012 · Cited by 37

Structure of Human Stabilin-1 Interacting Chitinase-like Protein (SI-CLP) Reveals a Saccharide-binding Cleft with Lower Sugar-binding Selectivity

Meng, G., Zhao, Y., Bai, X., Liu, Y., Green, T. J., Luo, M., & Zheng, X. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.130781 · Cited by 37

The optimal timing of continuous renal replacement therapy for patients with sepsis-induced acute kidney injury

Tian, H., Sun, T., Dong, H., Wang, T., Li, Z., Han, S., Qi, Z., Dong, Z., Lv, C., & Wang, X. (2014) · International Urology and Nephrology · doi:10.1007/s11255-014-0747-5 · Cited by 37

The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology

Alder, M. N., Lindsell, C. J., & Wong, H. R. (2014) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2014.912131 · Cited by 37

Interleukin‐33 contributes to ILC 2 activation and early inflammation‐associated lung injury during abdominal sepsis

Xu, H., Xu, J., Xu, L., Jin, S., Turnquist, H. R., Hoffman, R. A., Loughran, P., Billiar, T. R., & Deng, M. (2018) · Immunology and Cell Biology · doi:10.1111/imcb.12159 · Cited by 37

A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties

Wang, J., Ma, K., Ruan, M., Wang, Y., Li, Y., Fu, Y. V., Song, Y., Sun, H., & Wang, J. (2018) · PeerJ · doi:10.7717/peerj.5369 · Cited by 37

GPR18 expression on PMNs as biomarker for outcome in patient with sepsis

Zhang, L., Qiu, C., Yang, L., Zhang, Z., Zhang, Q., Wang, B., & Wang, X. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.11.061 · Cited by 37

H2S attenuates sepsis‑induced cardiac dysfunction via a PI3K/Akt‑dependent mechanism

Liu, J., Li, J., Tian, P., Guli, B., Weng, G., Li, L., & Cheng, Q. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.7440 · Cited by 38

Real-time bacterial detection with an intracellular ROS sensing platform

Hicks, J. M., Halkerston, R., Silman, N. J., Jackson, S. K., Aylott, J. W., & Rawson, F. J. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.111430 · Cited by 37

Polycaprolactone based nano-carrier for co-administration of moxifloxacin and rutin and its In-vitro evaluation for sepsis

Handa, M., Sharma, A., Verma, R. K., & Shukla, R. (2019) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2019.101286 · Cited by 38

Red blood cell-hitchhiking mediated pulmonary delivery of ivermectin: Effects of nanoparticle properties

Zheng, J., Lu, C., Ding, Y., Zhang, J., Tan, F., Liu, J., Yang, G., Wang, Y., Li, Z., Yang, M., et al. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121719 · Cited by 37

Production of interleukin‐27 by human neutrophils regulates their function during bacterial infection

Rinchai, D., Khaenam, P., Kewcharoenwong, C., Buddhisa, S., Sranujit, R. P., Chaussabel, D., Bancroft, G. J., & Lertmemongkolchai, G. (2012) · European Journal of Immunology · doi:10.1002/eji.201242526 · Cited by 37

Alveolar Macrophages from Septic Mice Promote Polymorphonuclear Leukocyte Transendothelial Migration via an Endothelial Cell Src Kinase/NADPH Oxidase Pathway

Wang, Z., Rui, T., Yang, M., Valiyeva, F., & Kvietys, P. R. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.12.8735 · Cited by 37

Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats

Godlewski, G., Malinowska, B., & Schlicker, E. (2004) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705839 · Cited by 37

Transforming Growth Factor-β, Macrophage Colony-Stimulating Factor and C-Reactive Protein Levels Correlate with CD14highCD16+ Monocyte Induction and Activation in Trauma Patients

West, S. D., Goldberg, D., Ziegler, A., Krencicki, M. A., Clos, T. W. D., & Mold, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052406 · Cited by 37

C1-esterase inhibitor attenuates the inflammatory response during human endotoxemia

Dorresteijn, M. J., Visser, T., Cox, L. A. E., Bouw, M. P. W. J. M., Pillay, J., Koenderman, A. H. L., Strengers, P. F. W., Leenen, L. P. H., van der Hoeven, J. G., Koenderman, L., et al. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181f17be4 · Cited by 37

Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C

Goring, K., Huang, Y., Mowat, C., Léger, C., Lim, T. H., Zaheer, R. S., Mok, D., Tibbles, L. A., Zygun, D., & Winston, B. W. (2009) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00071.2009 · Cited by 37

Suppression and Recovery of LPS-Stimulated Monocyte Activity After Trauma is Correlated With Increasing Injury Severity: A Prospective Clinical Study

Wutzler, S., Maier, M., Lehnert, M., Henrich, D. M., Walcher, F., Maegele, M., Laurer, H. L., & Marzi, İ. (2009) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0b013e3181968054 · Cited by 37

Morin hydrate augments phagocytosis mechanism and inhibits LPS induced autophagic signaling in murine macrophage

Jakhar, R., Paul, S., Chauhan, A. K., & Kang, S. C. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.07.020 · Cited by 37

Replacing animal experiments: choices, chances and challenges

Langley, G., Evans, T. J., Holgate, S. T., & Jones, A. K. P. (2007) · BioEssays · doi:10.1002/bies.20628 · Cited by 37

Prophylactic Antioxidant Potential of Gallic Acid in Murine Model of Sepsis

Maurya, H., Mangal, V., Gandhi, S., Prabhu, K., & Ponnudurai, K. (2014) · International Journal of Inflammation · doi:10.1155/2014/580320 · Cited by 37

The Anti-Inflammatory Effects of Ulinastatin in Trauma Patients with Hemorrhagic Shock

Park, K. H., Lee, K. H., Kim, H., & Hwang, S. O. (2009) · Journal of Korean Medical Science · doi:10.3346/jkms.2010.25.1.128 · Cited by 37

Inhibition of Complement and CD14 Attenuates theEscherichia coli-Induced Inflammatory Response in Porcine Whole Blood

Thorgersen, E. B., Pharo, A. M., Haverson, K., Axelsen, A. K., Gaustad, P., Kotwal, G. J., Sfyroera, G., & Mollnes, T. E. (2008) · Infection and Immunity · doi:10.1128/iai.01305-08 · Cited by 37

SRT1720, a sirtuin 1 activator, attenuates organ injury and inflammation in sepsis

Khader, A., Yang, W.-L., Hansen, L. W., Rajayer, S. R., Prince, J. M., Nicastro, J. M., Coppa, G. F., & Wang, P. (2017) · Journal of Surgical Research · doi:10.1016/j.jss.2017.06.031 · Cited by 37

The Antiinfective Effects of Velvet Antler of Formosan Sambar Deer (Cervus unicolor swinhoei) on Staphylococcus aureus‐Infected Mice

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