Cited by 224Chromosomal and Genetic VariationsDNA Repair MechanismsCRISPR and Genetic Engineering

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

Transposition of hAT elements links transposable elements and V(D)J recombination

Zhou, Liqin, Mitra, Rupak, Atkinson, Peter W., Burgess Hickman, Alison, Dyda, Fred, Craig, Nancy L.·2004·Nature

Open this paper in CoChat — free account

Abstract

Transposons are DNA sequences that encode functions that promote their movement to new locations in the genome. If unregulated, such movement could potentially insert additional DNA into genes, thereby disrupting gene expression and compromising an organism's viability. Transposable elements are classified by their transposition mechanisms and by the transposases that mediate their movement. The mechanism of movement of the eukaryotic hAT superfamily elements was previously unknown, but the divergent sequence of hAT transposases from other elements suggested that these elements might use a distinct mechanism. Here we have analysed transposition of the insect hAT element Hermes in vitro. Like other transposons, Hermes excises from DNA via double-strand breaks between the donor-site DNA and the transposon ends, and the newly exposed transposon ends join to the target DNA. Interestingly, the ends of the donor double-strand breaks form hairpin intermediates, as observed during V(D)J recombination, the process which underlies the combinatorial formation of antigen receptor genes. Significant similarities exist in the catalytic amino acids of Hermes transposase, the V(D)J recombinase RAG, and retroviral integrase superfamily transposases, thereby linking the movement of transposable elements and V(D)J recombination.

Integrity signals

Registry

Crossref · 10.1038/nature03157

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
Thompson, J. D., Higgins, D. G., & Gibson, T. J. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.22.4673 · Cited by 64,617
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
The sequence of the human genome
Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
The PSIPRED protein structure prediction server
McGuffin, L. J., Bryson, K., & Jones, D. T. (2000) · Bioinformatics · doi:10.1093/bioinformatics/16.4.404 · Cited by 3,887
Mobile DNA II
(2007) · Wiley eBooks · doi:10.1128/9781555817954 · Cited by 1,311
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
Ma, Y., Pannicke, U., Schwarz, K., & Lieber, M. R. (2002) · Cell · doi:10.1016/s0092-8674(02)00671-2 · Cited by 1,166
Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system
Agrawal, A., Eastman, Q. M., & Schatz, D. G. (1998) · Nature · doi:10.1038/29457 · Cited by 811
Crystal Structure of the Catalytic Domain of HIV-1 Integrase: Similarity to Other Polynucleotidyl Transferases
Dyda, F., Hickman, A. B., Jenkins, T. M., Engelman, A., Craigie, R., & Davies, D. R. (1994) · Science · doi:10.1126/science.7801124 · Cited by 810 · cited 1×
“Structural analysis of the HIV integrase and Mu and Tn5 transposases has previously demonstrated that the highly conserved catalytic DDE acidic amino acids lie on a common structure, that is, an RNaseH-like fold, and that they are closely juxtaposed, as appropriate for formation of a single active sit”
BackgroundSelf-citation
V(D)J Recombination: RAG Proteins, Repair Factors, and Regulation
Gellert, M. F. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.090501.150203 · Cited by 771
DNA Transposition by the RAG1 and RAG2 Proteins
Hiom, K., Melek, M., & Gellert, M. (1998) · Cell · doi:10.1016/s0092-8674(00)81587-1 · Cited by 534

Show all 50 references

Sorted by citations

Items 101–200 of 224

An Enzyme-Catalyzed Multistep DNA Refolding Mechanism in Hairpin Telomere Formation
Shi, K., Huang, W. M., & Aihara, H. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001472 · Cited by 23
Tools for Gene-Regulatory Analyses in the Marine Annelid Platynereis dumerilii
Backfisch, B., Козин, В. В., Kirchmaier, S., Tessmar‐Raible, K., & Raible, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093076 · Cited by 24
Transposable Element Annotation in Completely Sequenced Eukaryote Genomes
Flutre, T., Permal, E., & Quesneville, H. (2012) · Topics in current genetics · doi:10.1007/978-3-642-31842-9_2 · Cited by 22
V(D)J recombination: Born to be wild
Ramsden, D. A., Weed, B. D., & Reddy, Y. V. R. (2010) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2010.06.002 · Cited by 21
Human DNA Replication-related Element Binding Factor (hDREF) Self-association via hATC Domain Is Necessary for Its Nuclear Accumulation and DNA Binding
Yamashita, D., Komori, H., Higuchi, Y., Yamaguchi, T., Osumi, T., & Hirose, F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m607180200 · Cited by 21
Jumping Ahead with Sleeping Beauty: Mechanistic Insights into Cut-and-Paste Transposition
Ochmann, M. T., & Ivics, Z. (2021) · Viruses · doi:10.3390/v13010076 · Cited by 21
Transposon fingerprinting using low coverage whole genome shotgun sequencing in Cacao (Theobroma cacao L.) and related species
Sveinsson, S., Gill, N., Kane, N. C., & Cronk, Q. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-502 · Cited by 19
Functional characterization of the active Mutator-like transposable element, Muta1 from the mosquito Aedes aegypti
Liu, K., & Wessler, S. R. (2017) · Mobile DNA · doi:10.1186/s13100-016-0084-6 · Cited by 19
Breadth by depth: Expanding our understanding of the repair of transposon-induced DNA double strand breaks via deep-sequencing
Huefner, N. D., Mizuno, Y., Weil, C. F., Korf, I. F., & Britt, A. (2011) · DNA repair · doi:10.1016/j.dnarep.2011.07.011 · Cited by 19
Transpositionally active episomal hAT elements
O’Brochta, D. A., Stosic, C. D., Pilitt, K. L., Subramanian, R. A., Hice, R. H., & Atkinson, P. W. (2009) · BMC Molecular Biology · doi:10.1186/1471-2199-10-108 · Cited by 19
Self-citation
Transposable Element Dynamics of the hAT Element Herves in the Human Malaria Vector Anopheles gambiae s.s.
Subramanian, R. A., Arensburger, P., Atkinson, P. W., & O’Brochta, D. A. (2007) · Genetics · doi:10.1534/genetics.107.071811 · Cited by 19
Self-citation
Stress-induced transposition of Tn4652 in Pseudomonas putida
Ilves, H. (2006) · DSpace repository (University of Tartu) · Cited by 19
A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining
Runge, K. W., & Li, Y. (2017) · Current Genetics · doi:10.1007/s00294-017-0760-1 · Cited by 18
Transposition of the vertebrate Tol2 transposable element in Drosophila melanogaster
Urasaki, A., Mito, T., Noji, S., Ueda, R., & Kawakami, K. (2008) · Gene · doi:10.1016/j.gene.2008.08.008 · Cited by 18
Molecular characterization of the first intact Transib transposon from Helicoverpa zea
Chen, S., & Li, X. (2007) · Gene · doi:10.1016/j.gene.2007.10.015 · Cited by 18
A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming
Kesselring, L., Miskey, C., Zuliani, C., Querques, I., Kapitonov, V. V., Laukó, A., Fehér, A., Palazzo, A. J., Diem, T., Lustig, J., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz1119 · Cited by 18
Transposable Elements for Insect Transformation
Handler, A. M., & O’Brochta, D. A. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-384747-8.10004-2 · Cited by 17
Transposition of Mutator–like transposable elements (MULEs) resembles hAT and Transib elements and V(D)J recombination
Liu, K., & Wessler, S. R. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx357 · Cited by 17
Immunology in the spotlight at the Dover 'Intelligent Design' trial
Bottaro, A., Inlay, M. A., & Matzke, N. J. (2006) · Nature Immunology · doi:10.1038/ni0506-433 · Cited by 16
The diversification and activity of hAT transposons in Musa genomes
Menzel, G., Heitkam, T., Seibt, K. M., Nouroz, F., Müller-Stoermer, M., Heslop-Harrison, J. S., & Schmidt, T. (2014) · Chromosome Research · doi:10.1007/s10577-014-9445-5 · Cited by 14
Mobility properties of the Hermes transposable element in transgenic lines of Aedes aegypti
Smith, R. C., & Atkinson, P. W. (2010) · Genetica · doi:10.1007/s10709-010-9459-7 · Cited by 14
Self-citation
The effect of γ-radiation on induction of the hobo element transposition in Drosophila melanogaster
Zakharenko, L. P., Коваленко, Л. В., Perepelkina, M. P., & Захаров, И. К. (2006) · Russian Journal of Genetics · doi:10.1134/s1022795406060056 · Cited by 14
Hermes Transposon Distribution and Structure in Musca domestica
Subramanian, R. A., Cathcart, L. A., Krafsur, E. S., Atkinson, P. W., & O’Brochta, D. A. (2009) · Journal of Heredity · doi:10.1093/jhered/esp017 · Cited by 14
Self-citation
DNA sequence requirements for hobo transposable element transposition in Drosophila melanogaster
Kim, Y. J., Hice, R. H., O’Brochta, D. A., & Atkinson, P. W. (2011) · Genetica · doi:10.1007/s10709-011-9600-2 · Cited by 13
Self-citation
General survey of hAT transposon superfamily with highlight on hobo element in Drosophila
Ladevèze, V., Chaminade, N., Lemeunier, F., Périquet, G., & Aulard, S. (2012) · Genetica · doi:10.1007/s10709-012-9687-0 · Cited by 12
Mechanisms of DNA Transposition
Hickman, A. B., & Dyda, F. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch25 · Cited by 14
Self-citation
Roles of retrotransposons in benign and malignant hematologic disease.
Schneider, A. M., Duffield, A. S., Symer, D. E., & Burns, K. H. (2009) · PubMed · Cited by 13
A single active site in the mariner transposase cleaves DNA strands of opposite polarity
Bouuaert, C. C., & Chalmers, R. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx826 · Cited by 12
Diversification of hAT transposase paralogues in the sugarcane genome
de Jesus, E. M., Cruz, E. A. O., Cruz, G. M. Q., & Sluys, M. V. (2012) · Molecular Genetics and Genomics · doi:10.1007/s00438-011-0670-8 · Cited by 12
The architecture of the 12RSS in V(D)J recombination signal and synaptic complexes
Ciubotaru, M., Surleac, M. D., Metskas, L. A., Koo, P. K., Rhoades, E. R., Petrescu, A., & Schatz, D. G. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1348 · Cited by 12
Biochemical Characterization of Kat1: a Domesticated hAT-Transposase that Induces DNA Hairpin Formation and MAT-Switching
CHIRUVELLA, K. K., Rajaei, N., Jonna, V. R., Hofer, A., & Åström, S. U. (2016) · Scientific Reports · doi:10.1038/srep21671 · Cited by 12
Repetitive DNA elements as mediators of genomic change in response to environmental cues
Schmidt, A. L., & Anderson, L. M. (2007) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.2006.tb00217.x · Cited by 12
An integrative view of dynamic genomic elements influencing human brain evolution and individual neurodevelopment
Gericke, G. S. (2008) · Medical Hypotheses · doi:10.1016/j.mehy.2008.03.048 · Cited by 11
Mutator-Like Elements with Multiple Long Terminal Inverted Repeats in Plants
Ferguson, A. A., & Jiang, N. (2012) · Comparative and Functional Genomics · doi:10.1155/2012/695827 · Cited by 10
Tn7
Peters, J. E. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch30 · Cited by 10
The Origin of V(D)J Diversification
Hsu, E., & Lewis, S. M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397933-9.00009-6 · Cited by 10
Understanding how the V(D)J recombinase catalyzes transesterification: distinctions between DNA cleavage and transposition
Lu, C. P.-J., Posey, J. E., & Roth, D. B. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn128 · Cited by 10
Characteristics of MuA transposase-catalyzed processing of model transposon end DNA hairpin substrates
Saariaho, A.-H. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl405 · Cited by 10
Too many ends: aberrant transposition: Figure 1.Preprint
Weil, C. F. (2009) · Genes & Development · doi:10.1101/gad.1801309 · Cited by 10
Non-coding DNA – a brief review
Anandakumar, S., Arumugam, N., & Shanmughavel, P. (2017) · Journal of Applied Biology & Biotechnology · doi:10.7324/jabb.2017.50507 · Cited by 11
A systematic identification of Kolobok superfamily transposons in Trichomonas vaginalis and sequence analysis on related transposases
Meng, Q., Chen, K., Ma, L., Hu, S., & Yu, J. (2011) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jcg.2011.01.003 · Cited by 9
Insect Transposable Elements
Tu, Z. J. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-384747-8.10003-0 · Cited by 9
Analysis of mutagenic V(D)J recombinase mediated mutations at the HPRT locus as an in vivo model for studying rearrangements with leukemogenic potential in children
Finette, B. A. (2006) · DNA repair · doi:10.1016/j.dnarep.2006.05.023 · Cited by 9
The ESC: The Dangerous By-Product of V(D)J Recombination
Smith, A., Scott, J. N. F., & Boyes, J. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01572 · Cited by 8
Involvement of DNA Repair Genes and System of Radiation-Induced Activation of Transposons in Formation of Transgenerational Effects
Александровна, Ю. Е. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.596947 · Cited by 8
Alternative splicing of the maize Ac transposase transcript in transgenic sugar beet (Beta vulgaris L.)
Lisson, R., Hellert, J., Ringleb, M., Machens, F., Kraus, J., & Hehl, R. (2010) · Plant Molecular Biology · doi:10.1007/s11103-010-9651-2 · Cited by 8
Control of transposase activity within a transpososome by the configuration of the flanking DNA segment of the transposon
Mizuuchi, M., Rice, P. A., Wardle, S. J., Haniford, D. B., & Mizuuchi, K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706556104 · Cited by 8
Mariner and the ITm Superfamily of Transposons
Tellier, M., Bouuaert, C. C., & Chalmers, R. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch34 · Cited by 8
Hairpins at split ends in DNA
Oettinger, M. A. (2004) · Nature · doi:10.1038/432960b · Cited by 8
Thermal dependency of RAG1 self-association properties
De, P., Zhao, S., Gwyn, L. M., Godderz, L. J., Peak, M. M., & Rodgers, K. K. (2008) · BMC Biochemistry · doi:10.1186/1471-2091-9-5 · Cited by 8
Physiological significance of recombination‐activating gene 1 in neuronal death, especially optic neuropathy
Hirano, T., Murata, T., & Hayashi, T. (2014) · FEBS Journal · doi:10.1111/febs.13109 · Cited by 7
Purification, crystallization and preliminary crystallographic analysis of theHermestransposase
Perez, Z. N., Musingarimi, P., Craig, N. L., Dyda, F., & Hickman, A. B. (2005) · Acta Crystallographica Section F Structural Biology and Crystallization Communications · doi:10.1107/s1744309105015721 · Cited by 7
Self-citation
Birth of Three Stowaway-like MITE Families via Microhomology-Mediated Miniaturization of a Tc1/Mariner Element in the Yellow Fever Mosquito
Yang, G., Fattash, I., Lee, C., Liu, K., & Cavinder, B. (2013) · Genome Biology and Evolution · doi:10.1093/gbe/evt146 · Cited by 8
A Moveable Feast: An Introduction to Mobile DNA
Craig, N. L. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch1 · Cited by 7
Self-citation
Dissertationes bioscientiarum molecularium Universitatis Helsingiensis in Viikki
Saariaho, A.-H., Hilden, T. J., & Alaranta, A. (2006) · Cited by 7
Structure and Methyl-lysine Binding Selectivity of the HUSH Complex Subunit MPP8
Nikolopoulos, N., Oda, S.-I., Prigozhin, D. M., & Modis, Y. (2024) · Journal of Molecular Biology · doi:10.1016/j.jmb.2024.168890 · Cited by 10
Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding
Lannes, L., Furman, C. M., Hickman, A. B., & Dyda, F. (2023) · Nature Communications · doi:10.1038/s41467-023-40210-3 · Cited by 7
Self-citation
Interactions of Transposons with the Cellular DNA Repair Machinery
Izsvák, Z., Wang, Y., & Ivics, Z. (2009) · Genome dynamics and stability · doi:10.1007/7050_2008_043 · Cited by 6
Transposon Excision from an Atypical Site: A Mechanism of Evolution of Novel Transposable Elements
Langer, M., Sniderhan, L. F., Grossniklaus, U., & Ray, A. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000965 · Cited by 6
Transposons and Gene Creation
Dooner, H. K., & Weil, C. F. (2013) · doi:10.1002/9781118500156.ch8 · Cited by 6
The hobo, Hermes and Herves Transposable Elements of Insects
Atkinson, P. W., O’Brochta, D. A., & Craig, N. L. (2007) · Springer eBooks · doi:10.1007/978-1-4020-6059-5_4 · Cited by 5
Self-citation
hAT Transposable Elements
Atkinson, P. W. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch35 · Cited by 5
Self-citation
Insect Transgenesis: Mechanisms, Applications, and Ecological Safety
Handler, A. M., & Atkinson, P. W. (2006) · Biotechnology and Genetic Engineering Reviews · doi:10.1080/02648725.2006.10648082 · Cited by 5
Self-citation
Flexibility in MuA Transposase Family Protein Structures: Functional Mapping with Scanning Mutagenesis and Sequence Alignment of Protein Homologues
Rasila, T. S., Vihinen, M., Paulin, L. G., Haapa-Paananen, S. M., & Savilahti, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037922 · Cited by 4
Fusion of reverse-oriented Ds termini following abortive transposition in Arabidopsis: implications for the mechanism of Ac/Ds transposition
Krishnaswamy, L., Zhang, P., & Peterson, T. (2010) · Plant Cell Reports · doi:10.1007/s00299-010-0832-x · Cited by 4
Induction of transpositions of hobo-elements in chronically irradiated cells of dysgenetic and non-dysgenetic individuals of Drosophila melanogaster
Александровна, Ю. Е., & Зайнуллин, В. Г. (2014) · Russian Journal of Genetics · doi:10.1134/s1022795414050123 · Cited by 4
Useful parasites: the evolutionary biology and biotechnology applications of transposable elements
Bonchev, G. (2016) · Journal of Genetics · doi:10.1007/s12041-016-0702-6 · Cited by 4
Beyond inversions and deletions: the evolutionary and functional insights from translocations, fissions, and fusions in animal genomes
Diblasi, C., & Saitou, M. (2025) · Heredity · doi:10.1038/s41437-025-00785-7 · Cited by 5
The Role of Human Endogenous Retroviruses (HERVs) in the Pathologies of the Nervous System
Kõks, S., & Kõks, G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-804078-2.00022-2 · Cited by 3
THAP9 Transposase Cleaves DNA via Conserved Acidic Residues in an RNaseH-Like Domain
Sharma, V., Thakore, P., & Majumdar, S. (2021) · Cells · doi:10.3390/cells10061351 · Cited by 3
Transposons Tn10 and Tn5
Haniford, D. B., & Ellis, M. J. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch29 · Cited by 3
The Mechanism ofAc/DsTransposition
Peterson, T., & Zhang, P. (2013) · doi:10.1002/9781118500156.ch3 · Cited by 3
Characterization of hAT DNA transposon superfamily in the genome of Neotropical fish Apareiodon sp.
de Oliveira, F. S., Azambuja, M., Schemberger, M. O., Nascimento, V. D., Oliveira, J. I. N., Wolf, I. R., Nogaroto, V., Martins, C., & Vicari, M. R. (2024) · Molecular Genetics and Genomics · doi:10.1007/s00438-024-02190-x · Cited by 2
V(D)J Recombination: Mechanism and Consequences
Gellert, M. F. (2006) · Springer eBooks · doi:10.1007/4735_2006_0206 · Cited by 2
Transposable Elements Shaping the Epigenome
Giménez-Orenga, K., & Oltra, E. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91909-8.00035-9 · Cited by 3
Unique structure (construction and configuration) and evolution of the array of small serum protein genes of Protobothrops flavoviridis snake
Chijiwa, T., Inamaru, K., Takeuchi, A., Maeda, M., Yamaguchi, K., Shibata, H., Hattori, S., Oda‐Ueda, N., & Ohno, M. (2019) · Bioscience Reports · doi:10.1042/bsr20190560 · Cited by 2
DNA bending in the synaptic complex in V(D)J recombination: turning an ancestral transpososome upside down
Ciubotaru, M., Surleac, M. D., Musat, M. G., Rusu, A. M., Ionita, E., & Albu, P. C. (2014) · Discoveries · doi:10.15190/d.2014.5 · Cited by 2
Nomadic genetic elements contribute to oncogenic translocations: Implications in carcinogenesis
Sridaran, D., & Premkumar, K. (2015) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2015.10.012 · Cited by 2
Transposons Ac/Ds, En/Spmand their Relatives in Maize
Zhang, P., Peterson, T., & Petérson, P. A. (2009) · Springer eBooks · doi:10.1007/978-0-387-77863-1_13 · Cited by 2
Transposition of Reversed Ac Element Ends Generates Novel Chimeric Genes in Maize
Zhang, P., Zhang, F., & Peterson, T. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0020164.eor · Cited by 2
Characterization of the molecular components and function of BARE-1, Hin-Mu and Mu transposition machineries
Saariaho, A.-H. (2006) · Työväentutkimus Vuosikirja · Cited by 2
SURE e Garapa: caracterização molecular e distribuição de dois retrotransposons com LTR em cana-de-açúcar.
Domingues, D. S. (2009) · doi:10.11606/t.87.2009.tde-28042009-115618 · Cited by 2
Structure of the tripartite motif of KAP1/TRIM28 identifies molecular interfaces required for transcriptional silencing of retrotransposonsPreprint
Stoll, G. A., Oda, S.-I., Chong, Z., Yu, M., McLaughlin, S. H., & Modis, Y. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/505677 · Cited by 2
Proposed Uses of Transposons in Insect and Medical Biotechnology
Peter, A. (2008) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-78225-6_5 · Cited by 2
Cross-species analysis of the nuclease Artemis highlights its evolving function in domesticating RAG-like transposons and residues that are crucial for activity
Huang, Z., Cai, Z., Tao, X., Wang, X., Tian, X., Chen, F., Li, Z., Xu, A., & Yuan, S. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003056 · Cited by 1
An assay to monitor the activity of DNA transposition complexes yields a general quality control measure for transpositional recombination reactions
Pulkkinen, E., Haapa-Paananen, S. M., & Savilahti, H. (2014) · Mobile Genetic Elements · doi:10.4161/21592543.2014.969576 · Cited by 1
Sleeping BeautyTransposition
Ivics, Z., & Izsvák, Z. (2015) · ASM Press eBooks · doi:10.1128/9781555819217.ch38 · Cited by 1
The Origin of V(D)J Diversification
Hsu, E., & Lewis, S. M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-95895-0.00017-9 · Cited by 1
Bioinformatics studies on the mechanisms of gene regulation in vertebrates
Ghazal, A. (2014) · Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences)) · Cited by 1
L'annotation des éléments transposables par la compréhension de leur diversification
Flutre, T. (2010) · HAL
Mu in vitro Transposition Technology in Functional Genetics and Genomics: Applications on Mouse and Bacteriophages
Vilén, H. (2006) · Työväentutkimus Vuosikirja
Mechanism of Single‐Stranded DNA Transposition: A Structural Perspective
Barábas, O. (2012) · Wiley eBooks · doi:10.1002/9780470015902.a0023178
Transposable prophage Mu exists as an independent chromosomal domain in E. coli
Lou, Z. (2012) · Texas ScholarWorks (Texas Digital Library)
In vitro Study of Herves Transposable Element of Anopheles gambiae and Use of RNA Interference (RNAi) in Culex quinquefasciatus
Kahlon, A. S. (2010) · eScholarship (California Digital Library)
Profile of Nancy L. Craig
Trivedi, B. P. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1212357109
Repair of endonuclease- and transposon-induced DNA double strand breaks by host factors in Arabidopsis
Li, Z. (2006) · doi:10.31274/rtd-180813-1124
Inverted repeats as a source of eukaryotic genome instability
Narayanan, V. (2008) · SMARTech Repository (Georgia Institute of Technology)
Functional Mapping of Mu Transposition Machinery : MuA Protein Modification and Engineering for Hyperactivity
Rasila, T. S. (2013) · Työväentutkimus Vuosikirja
The genetics of hybrid incompatibility early in the 'speciation continuum'
Watson, E. T. (2014) · UTA ResearchCommons (University of Texas Arlington)
The rmal Dependency of RAG1 S elf-association Properties
De, P., Zhao, S., & Gwyn, L. M. (2008)

Authors: Zhou, L., Mitra, R., Atkinson, P. W., Burgess Hickman, A., Dyda, F., & Craig, N. L.
Affiliations: Howard Hughes Medical Institute (US)
University of California, Riverside (US)
National Institutes of Health (US)
Corresponding author: Craig, Nancy L.
ORCID: Zhou, Liqin
Atkinson, Peter W.
Dyda, Fred
Craig, Nancy L.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 2004-12
Volume: 432
Issue: 7020
Pages: 995-1001
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/nature03157
OpenAlex: W2071441005
Cited by: 224
References: 50
Citations by year: 2026: 2 · 2025: 5 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 7 · 2016: 6 · 2015: 23 · 2014: 15 · 2013: 11 · 2012: 19
FWCI: 20.37
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
RePEc: Research Papers in Economics (submittedVersion)
Funders: Howard Hughes Medical Institute
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Chromosomal and Genetic Variations
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
Keywords: hAT transposons, transposition mechanism, V(D)J recombination, DNA double-strand breaks, transposon excision
MeSH terms: Animals, Base Sequence, Binding Sites, DNA, DNA Transposable Elements, Drosophila melanogaster, Nucleic Acid Conformation, Recombination, Genetic, Substrate Specificity, Gene Rearrangement, B-Lymphocyte, Homeodomain Proteins, Transposases

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Transposition of hAT elements links transposable elements and V(D)J recombination

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks