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The developmental genetics of congenital heart disease
Abstract
Congenital heart disease is the leading cause of infant morbidity in the Western world, but only in the past ten years has its aetiology been understood. Recent studies have uncovered the genetic basis for some common forms of the disease and provide new insight into how the heart develops and how dysregulation of heart development leads to disease.
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Loss-of-function of individual kernel TFs can disrupt heart development.
“Loss-of-function of individual kernel TFs can disrupt heart development [6]”
From A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease (2021) · cites this paper as [6]
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Metadata
- Authors
- Bruneau, B. G.
- Venue
- Nature
- Published
- 2008-02
- Volume
- 451
- Issue
- 7181
- Pages
- 943-948
- ISSN
- 0028-0836
- 1476-4687
- Cited by
- 687
- References
- 7
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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