Misfolded proteins partition between two distinct quality control compartments

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Particle-Rich Cytoplasmic Structure (PaCS): Identification, Natural History, Role in Cell Biology and Pathology

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Polyglutamine Expansion Alters the Dynamics and Molecular Architecture of Aggregates in Dentatorubropallidoluysian Atrophy

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Fluorogenic detection of protein aggregates in live cells using the AggTag method

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Severe ethanol stress induces the preferential synthesis of mitochondrial disaggregase Hsp78 and formation of DUMPs in Saccharomyces cerevisiae

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Proteotoxic stress disrupts epithelial integrity by inducing MTOR sequestration and autophagy overactivation

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RNA condensation fluidizes the cytoplasm

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Hsp90 Maintains Proteostasis of the Galactose Utilization Pathway To Prevent Cell Lethality

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The Emerging Roles of Early Protein Folding Events in the Secretory Pathway in the Development of Neurodegenerative Maladies

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Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast

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Differential Interactions of Molecular Chaperones and Yeast Prions

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Recruitment of the oncoprotein v-ErbA to aggresomes

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Crowding versus molecular seeding: NMR studies of protein aggregation in hen egg white

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A yeast model for polyalanine-expansion aggregation and toxicity

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Protein Nano-Fibrilar Structure and Associated Diseases

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Quiescent cells maintain active degradation-mediated protein quality control requiring proteasome, autophagy, and nucleus-vacuole junctions

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Autophagy Dysfunction and Neurodegeneration: Where Does It Go Wrong?

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Proteostasis in cellular dormancy: lessons from yeast to oocytes

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Metabolically regulated proteasome supramolecular organization in situ

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A Reporter System for Cytosolic Protein Aggregates in Yeast

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Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates

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Q-bodies monitor the quinary state of the protein fold

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Cytosolic aggregates in presence of non‐translocated proteins perturb endoplasmic reticulum structure and dynamics

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The Proteasome Lid Triggers COP9 Signalosome Activity during the Transition of Saccharomyces cerevisiae Cells into Quiescence

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Mechanisms Underlying the Cellular Clearance of Antitrypsin Z: Lessons from Yeast Expression Systems

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Analytical model for macromolecular partitioning during yeast cell division

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A budding yeast's perspective on aging: The shape I'm in

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Structural Mapping of Protein Aggregates in Live Cells Modeling Huntington's Disease

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Polyamines interfere with protein ubiquitylation and cause depletion of intracellular amino acids: a possible mechanism for cell growth inhibition

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Sequestrase chaperones protect against oxidative stress-induced protein aggregation and [PSI+] prion formation

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Elimination of virus-like particles reduces protein aggregation and extends replicative lifespan in Saccharomyces cerevisiae

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Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment

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Fitness Costs of Minimal Sequence Alterations Causing Protein Instability and Toxicity

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Characterization of Aggregate Load and Pattern in Living Yeast Cells by Flow Cytometry

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Vesicle‐mediated secretion of misfolded prion protein molecules from cyclosporin A‐treated cells

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Methods for measuring misfolded protein clearance in the budding yeast Saccharomyces cerevisiae

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Defining the mechanism of PDI interaction with disulfide-free amyloidogenic proteins: Implications for exogenous protein expression and neurodegenerative disease

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Tuning Surface Charges of Peptide Nanofibers for Induction of Antigen-Specific Immune Tolerance: An Introductory Study

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Sup35 methionine oxidation is a trigger forde novo[PSI+] prion formation

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Patterns of [PSI+] aggregation allow insights into cellular organization of yeast prion aggregates

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Derivation of a solubility condition for proteins from an analysis of the competition between folding and aggregation

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Imperfect asymmetry: The mechanism governing asymmetric partitioning of damaged cellular components during mitosis

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Heat Shock Proteins and Protein Quality Control in Alzheimer’s Disease

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Endoplasmic Reticulum (ER) Reorganization and Intracellular Retention of CD58 Are Functionally Independent Properties of the Human Cytomegalovirus ER-Resident Glycoprotein UL148

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A biosensor of protein foldedness identifies increased “holdase” activity of chaperones in the nucleus following increased cytosolic protein aggregation

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Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V

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Clearance of protein aggregates during cell divisionPreprint

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A nuclear protein quality control system for elimination of nucleolus-related inclusions

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The Effect of Calorie Restriction on Protein Quality Control in Yeast

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microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes

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Toxicity of the model protein 3×GFP arises from degradation overload, not from aggregate formation

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Isoform-specific sequestration of protein kinase A fine-tunes intracellular signaling during heat stress

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Macroautophagy of Aggregation-Prone Proteins in Neurodegenerative Disease

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Toxoplasma gondii Clp family protein: TgClpB1 plays a crucial role in thermotolerance

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Molecular chaperones: from proteostasis to pathogenesis

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Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation

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Quantitative photoconversion analysis of internal molecular dynamics in stress granules and other membraneless organelles in live cells

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Chaperone molecules concentrate together with the ubiquitin–proteasome system inside particulate cytoplasmic structures: possible role in metabolism of misfolded proteins

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Calcineurin stimulation by Cnb1p overproduction mitigates protein aggregation and α-synuclein toxicity in a yeast model of synucleinopathy

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Getting stress out of stressed‐out stress granules

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Nab3’s localization to a nuclear granule in response to nutrient deprivation is determined by its essential prion-like domain

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Proteotoxic stress promotes entrapment of ribosomes and misfolded proteins in a shared cytosolic compartment

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Cdc48 regulates intranuclear quality control sequestration of the Hsh155 splicing factor in budding yeast

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Hitchhiking vesicular transport routes to the vacuole: Amyloid recruitment to the Insoluble Protein Deposit (IPOD)

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Nuclear bodies protect phase separated proteins from degradation in stressed proteomePreprint

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Co-chaperones fine-tune the function of heat shock protein 70 (Hsp70), whether to fold, hold, or degrade substrates in ensuring cellular protein homeostasis

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The Cellular Isopeptidase T Deubiquitinating Enzyme Regulates Kaposi’s Sarcoma-Associated Herpesvirus K7 Degradation

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Cytoplasmic redox imbalance in the thioredoxin system activates Hsf1 and results in hyperaccumulation of the sequestrase Hsp42 with misfolded proteins

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Dynamics of DNA damage-induced nuclear inclusions are regulated by SUMOylation of Btn2

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K29-linked free polyubiquitin chains affect ribosome biogenesis and direct ribosomal proteins to the intranuclear quality control compartment

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Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3

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Autophagy machinery promotes the chaperone-mediated formation and compartmentalization of protein aggregates during appressorium development by the rice blast fungus

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Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins

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A bipolar functionality of Q/N‐rich proteins: Lsm4 amyloid causes clearance of yeast prions

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Levels of metacaspase1 and chaperones related to protein quality control in alcoholic and nonalcoholic steatohepatitis

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Molecular dynamics study on the stability of wild-type and the R220K mutant of human prion protein

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Yeast screening platform identifies FDA-approved drugs that reduce Aβ oligomerization

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Heterogeneous interaction network of yeast prions and remodeling factors detected in live cells

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