p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Takahashi, K., & Yamanaka, S. (2006) · Cell · doi:10.1016/j.cell.2006.07.024 · Cited by 26,673

The 2007 WHO Classification of Tumours of the Central Nervous System

Louis, D. N., Ohgaki, H., Wiestler, O. D., Cavenee, W. K., Burger, P. C., Jouvet, A., Scheithauer, B. W., & Kleihues, P. (2007) · Acta Neuropathologica · doi:10.1007/s00401-007-0243-4 · Cited by 15,656

In silico prediction of protein-protein interactions in human macrophages

Souiai, O., Guerfali, F. Z., Miled, S. B., Brun, C., & Benkahla, A. (2014) · BMC Research Notes · doi:10.1186/1756-0500-7-157 · Cited by 10,785

Significance analysis of microarrays applied to the ionizing radiation response

Tusher, V. G., Tibshirani, R., & Chu, G. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091062498 · Cited by 10,568

Erratum to: The 2007 WHO classification of tumours of the central nervous system

Louis, D. N., Ohgaki, H., Wiestler, O. D., Cavenee, W. K., Burger, P. C., Jouvet, A., Scheithauer, B. W., & Kleihues, P. (2007) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-156115 · Cited by 4,435

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection.

Li, C., & Wong, W. H. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.1.31 · Cited by 3,133

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.

Clarke, M. F., Dick, J. E., Dirks, P. B., Eaves, C., Jamieson, C., Jones, D. L., Visvader, J., Weissman, I. L., & Wahl, G. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-3126 · Cited by 3,124

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

Ben‐Porath, I., Thomson, M., Carey, V. J., Ge, R., Bell, G. W., Regev, A., & Weinberg, R. A. (2008) · Nature Genetics · doi:10.1038/ng.127 · Cited by 2,571

Malignant astrocytic glioma: genetics, biology, and paths to treatment

Furnari, F. B., Fenton, T., Bachoo, R. M., Mukasa, A., Stommel, J. M., Stegh, A., Hahn, W. C., Ligon, K. L., Louis, D. N., Brennan, C., et al. (2007) · Genes & Development · doi:10.1101/gad.1596707 · Cited by 2,316

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stabilityPreprint

Sears, R. C., Nuckolls, F., Haura, E. B., Taya, Y., Tamai, K., & Nevins, J. R. (2000) · Genes & Development · doi:10.1101/gad.836800 · Cited by 1,411

Single-Cell Transcriptomics Unveils the Dedifferentiation Mechanism of Lung Adenocarcinoma Stem Cells

Pan, Z., Zhang, M., Zhang, F., Pan, H., Li, Y., Shao, Y., Yuan, X. T., Wang, J., & Chen, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010482 · Cited by 11

Phage Display Targeting Identifies Eya1 as a Regulator of Glioblastoma Stem Cell Maintenance and Proliferation

Kim, J., She, C., Potez, M., Huang, P. C., Wu, Q., Prager, B. C., Qiu, Z., Bao, S., Rich, J. N., & Liu, J. K. (2021) · Stem Cells · doi:10.1002/stem.3355 · Cited by 11

PEAMOtecan, a novel chronotherapeutic polymeric drug for brain cancer

Allen, J., Wang, J., Zolotarskaya, O. Y., Sule, A. D., Mohammad, S., Arslan, S., Wynne, K. J., Yang, H., & Valerie, K. C. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.02.003 · Cited by 11

Hypoxia, Gene Expression, and Metastasis

Razorenova, O. V., & Giaccia, A. J. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6615-5_3 · Cited by 11

Deciphering single-cell heterogeneity and cellular ecosystem dynamics during prostate cancer progressionPreprint

Zhao, F., Zeng, J., Chen, C., Zhao, X., Zhang, T., THOMAS, G. V., Sears, R. C., Alumkal, J. J., Moran, A. E., Mills, G. B., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.18.629070 · Cited by 12

In vivo mouse models for adult brain tumors: Exploring tumorigenesis and advancing immunotherapy development

Figg, J., Chen, D., Font, L. F., Flores, C., & Jin, D. (2024) · Neuro-Oncology · doi:10.1093/neuonc/noae131 · Cited by 11

Somatostatin Receptor Splicing Variant sst5TMD4 Overexpression in Glioblastoma Is Associated with Poor Survival, Increased Aggressiveness Features, and Somatostatin Analogs Resistance

Fuentes-Fayos, A. C., G-García, M. E., Pérez‐Gómez, J. M., Peel, A., Blanco-Acevedo, C., Solivera, J., Ibáñez‐Costa, A., Gahete, M. D., Castano, J. P., & Luque, R. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031143 · Cited by 10

Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape

Boot, J. R., Rosser, G., Kancheva, D., Vinel, C., Lim, Y. M., Pomella, N., Zhang, X., Guglielmi, L., Sheer, D., Barnes, M. R., et al. (2022) · eLife · doi:10.7554/elife.77335 · Cited by 10

Lysine-specific methyltransferase Set7/9 in stemness, differentiation, and development

Daks, A. A., Parfenyev, S. E., Shuvalov, O. Y., Fedorova, O., Nazarov, A., Melino, G., & Barlev, N. A. (2024) · Biology Direct · doi:10.1186/s13062-024-00484-z · Cited by 10

Cryopreservation of cancer-initiating cells derived from glioblastoma

Tang, C. (2010) · Frontiers in Bioscience-Scholar · doi:10.2741/s181 · Cited by 10

PIK3R1Met326Ile germline mutation correlates with cysteine-rich protein 61 expression and poor prognosis in glioblastoma

Otani, Y., Ishida, J., Kurozumi, K., Oka, T., Shimizu, T., Tomita, Y., Hattori, Y., Uneda, A., Matsumoto, Y., Michiue, H., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-07745-0 · Cited by 13

Bioinformatical analysis of gene expression signatures of different glioma subtypes

Wang, R., Wei, J., Li, Z., Tian, Y., & Du, C. (2017) · Oncology Letters · doi:10.3892/ol.2017.7660 · Cited by 10

Neoplastic Cells are the Major Source of MT-MMPs in IDH1-Mutant Glioma, Thus Enhancing Tumor-Cell Intrinsic Brain Infiltration

Thome, I., Lacle, R., Voß, A., Bortolussi, G., Pantazis, G., Schmidt, A., Conrad, C., Jacob, R., Timmesfeld, N., Bartsch, J. W., et al. (2020) · Cancers · doi:10.3390/cancers12092456 · Cited by 11

Involvement of the Catecholamine Pathway in Glioblastoma Development

Krabóth, Z., Kajtár, B., Gálik, B., Gyenesei, A., Miseta, A., & Kálmán, B. (2021) · Cells · doi:10.3390/cells10030549 · Cited by 12

Network pharmacological analysis of active components of Xiaoliu decoction in the treatment of glioblastoma multiforme

Wu, J., Li, X., Liang, J. Y., Fang, D., Yang, Z.-J., Wei, J., & Chen, Z. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.940462 · Cited by 10

dp53 Restrains Ectopic Neural Stem Cell Formation in the Drosophila Brain in a Non-Apoptotic Mechanism Involving Archipelago and Cyclin E

Ouyang, Y., Song, Y., & Lu, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028098 · Cited by 10

Maintenance of Critical Properties of Brain Tumor Stem-like Cells After Cryopreservation

Mao, X., Guo, G., Wang, P., Zhang, X., Xue, X., Zhang, W., Fei, Z., Jiang, X., & Yan, M. (2010) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-010-9505-0 · Cited by 10

Stanniocalcin 1 is a prognostic biomarker in glioma

Luo, W., Chen, D., Wang, H., & Hu, J. (2020) · Oncology Letters · doi:10.3892/ol.2020.11792 · Cited by 10

The Adolescent and Young Adult with Cancer: State of the Art—Brain Tumor

Epelman, S. (2013) · Current Oncology Reports · doi:10.1007/s11912-013-0329-1 · Cited by 10

Proliferating cell nuclear antigen, p53 and micro vessel density: Grade II vs. Grade III astrocytoma

Husain, N., Malhan, P., Bhalla, S., Gupta, R., & Husain, M. (2010) · Indian Journal of Pathology and Microbiology · doi:10.4103/0377-4929.59177 · Cited by 9

Impaired TGF-β induced growth inhibition contributes to the increased proliferation rate of neural stem cells harboring mutant p53.

Kumar, P., Naumann, U., Aigner, L., Wischhusen, J., Beier, C. P., & Beier, D. (2015) · PubMed Central · Cited by 9

Disposable Stochastic Sensor Based on Deposition of a Nanolayer of Silver on Silk for Molecular Recognition of Specific Biomarkers

Staden, R. S., Gheorghe, S. S., Ilie‐Mihai, R., & Bădulescu, M. (2021) · Journal of The Electrochemical Society · doi:10.1149/1945-7111/abeea2 · Cited by 9

Comprehensive analyses indicated the association between m6A related long non‐coding RNAs and various pathways in glioma

Chen, Z., Zhang, W., Yan, Z., & Zhang, M. (2022) · Cancer Medicine · doi:10.1002/cam4.4913 · Cited by 9

Upregulation of the Renin–Angiotensin System Is Associated with Patient Survival and the Tumour Microenvironment in Glioblastoma

Lozinski, M., Lumbers, E. R., Bowden, N. A., Martin, J. H., Fay, M. F., Pringle, K. G., & Tooney, P. A. (2024) · Cells · doi:10.3390/cells13070634 · Cited by 9

Overexpression Models: Lentiviral Modeling of Brain Cancer

Friedmann‐Morvinski, D., & Singer, O. (2013) · Current Protocols in Mouse Biology · doi:10.1002/9780470942390.mo110271 · Cited by 9

Isolation, cultivation and identification of brain glioma stem cells by magnetic bead sorting.

Zhou, X., Zheng, C., Shi, Q., Li, X., Shen, Z., & Yu, R. (2012) · PubMed Central · doi:10.3969/j.issn.1673-5374.2012.13.004 · Cited by 9

Upregulation of DNA Metabolism-Related Genes Contributes to Radioresistance of Glioblastoma

Wang, C., Zheng, W., Yao, D., Chen, Q., Zhu, L., Zhang, J., Pan, Y., Zhang, J., & Shao, C. (2019) · Human Gene Therapy Clinical Development · doi:10.1089/humc.2018.251 · Cited by 9

Organ-specific regulation of CHD1 by acute PTEN and p53 loss in mice

Rahmy, S., Cheng, X., Wang, M., Feng, H., Qiu, W., Zhao, R., & Lü, X. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.02.136 · Cited by 9

Tumor Microenvironment — Perivascular and Perinecrotic Niches

Schiffer, D., Mellai, M., Annovazzi, L., Casalone, C., & Cassoni, P. (2015) · InTech eBooks · doi:10.5772/58962 · Cited by 9

The Side Story of Stem-like Glioma Cells

Persson, A. I., & Weiss, W. A. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.02.004 · Cited by 9

Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK

Katz, S. G., Fisher, J. K., Correll, M., Bronson, R. T., Ligon, K. L., & Walensky, L. D. (2012) · Oncogene · doi:10.1038/onc.2012.421 · Cited by 9

Differentiation of SWO-38 glioma cells induced by CDA-2 is mediated by peroxisome proliferator-activated receptor γ

Lin, C., Wang, M. H., Qin, Y., Mao, F., Xie, B., & Zhong, X. Y. (2009) · Journal of Neuro-Oncology · doi:10.1007/s11060-009-9900-x · Cited by 9

Role of Btg2 in the Progression of a PDGF-Induced Oligodendroglioma Model

Appolloni, I., Curreli, S., Caviglia, S., Barilari, M., Gambini, E., Pagano, A., & Malatesta, P. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms131114667 · Cited by 9

Chronic Stress Does Not Influence the Survival of Mouse Models of Glioblastoma

Lopes, M., de Castro, J. V., Pojo, M., Gonçalves, C. S., Martins, E. P., Coimbra, B., Sotiropoulos, I., Sousa, N., Rodrigues, A. J., & Costa, B. M. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.856210 · Cited by 8

BRCA1 and ELK-1 regulate neural progenitor cell fate in the optic tectum in response to visual experience in Xenopus laevis tadpoles

Huang, L.-C., McKeown, C. R., He, H., Ta, A. C., & Cline, H. T. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2316542121 · Cited by 8

The genetic duet of concurrent RASAL1 and PTEN alterations promotes cancer aggressiveness by cooperatively activating the PI3K – AKT pathway

Shen, X., Tan, J., Liu, R., Zhu, G., Rooper, L. M., & Xing, M. (2024) · Molecular Oncology · doi:10.1002/1878-0261.13701 · Cited by 8

The subventricular zone structure, function and implications for neurological disease

Li, K., Zheng, Y., Cai, S., Fan, Z., Yang, J., Liu, Y., Liang, S., Song, M., Du, S., & Qi, L. (2024) · Genes & Diseases · doi:10.1016/j.gendis.2024.101398 · Cited by 9

p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy

Haaland, I., Hjelle, S. M., Reikvam, H., Sulen, A., Ryningen, A., McCormack, E., Bruserud, Ø., & Gjertsen, B. T. (2021) · Cells · doi:10.3390/cells10040833 · Cited by 9

The concept of radiation-enhanced stem cell differentiation

Mieloch, A. A., & Suchorska, W. M. (2015) · Radiology and Oncology · doi:10.1515/raon-2015-0022 · Cited by 8

Stem cells in cancer therapy: From their role in pathogenesis to their use as therapeutic agents

Aimola, P., Desiderio, V., Graziano, A., & Claudio, P. P. (2010) · Drug News & Perspectives · doi:10.1358/dnp.2010.23.3.1489979 · Cited by 8

Functional and pathway enrichment analysis for integrated regulatory network of high- and low-metastatic lung cancer

Chen, Q., Jiao, D., Wu, Y.-Q., Wang, L., Hu, H., Song, J., Yan, J., & Wu, L. (2013) · Molecular BioSystems · doi:10.1039/c3mb70288j · Cited by 8

1.4.3 The vector meson nonet (1- states)

Castro-Melchor, M., Le, H., & Hu, W. (2005) · Springer eBooks · doi:10.1007/10201111_6 · Cited by 8

The Continuing Evolution

Kaye, A. H., & Morokoff, A. P. (2014) · Neurosurgery · doi:10.1227/neu.0000000000000388 · Cited by 8

Leucine-rich glioma inactivated 3: integrative analyses support its prognostic role in glioma

Kwon, N. S., Kim, D., & Yun, H. (2017) · OncoTargets and Therapy · doi:10.2147/ott.s138912 · Cited by 8

The Pivotal Immunomodulatory and Anti-Inflammatory Effect of Histone-Lysine N-Methyltransferase in the Glioma Microenvironment: Its Biomarker and Therapy Potentials

Richard, S. A., & Kuugbee, E. D. (2021) · Analytical Cellular Pathology · doi:10.1155/2021/4907167 · Cited by 8

Directional migration of adult hematopoeitic progenitors to C6 glioma in vitro

Bryukhovetskiy, I., Mischenko, P., Толок, Е. В., Zaitsev, S., Khotimchenko, Y. S., & Bryukhovetskiy, A. S. (2015) · Oncology Letters · doi:10.3892/ol.2015.2952 · Cited by 8

DJ-1 Contributes to Self-renewal of Stem Cells in the U87-MG Glioblastoma Cell Line

Toda, Y., YOSHIMURA, R., ITAHARA, M., Imai, Y., Yamada, K., UNO, T., Nakata, S., Hosogi, S., Takata, K., & Ashihara, E. (2019) · Anticancer Research · doi:10.21873/anticanres.13803 · Cited by 8

Glioblastoma: From Pathophysiology to Novel Therapeutic Approaches

Ribeiro, A., Fote, G., Himstead, A. S., Zheng, M., Elliott, E., Smith, S. M., Lou, J. J., & Yuen, C. (2025) · Biomedicines · doi:10.3390/biomedicines13081963 · Cited by 7

Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss

Mejía-Hernández, J. O., Keam, S. P., Saleh, R., Muntz, F., Fox, S. B., Byrne, D. J., Kogan, A., Pang, L., Huynh, J., Litchfield, C., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05211-y · Cited by 7

Pre-Clinical Models for CAR T-Cell Therapy for Glioma

Vandecandelaere, G., Ramapriyan, R., Gaffey, M., Richardson, L. G., Steuart, S. J., Tazhibi, M., Kalaw, A., Grewal, E. P., Sun, J., Curry, W. T., et al. (2024) · Cells · doi:10.3390/cells13171480 · Cited by 8

Efficacy Confirmation Test of Immature Asian Pear (Pyrus pyrifolia Nakai) Extract on Ovalbumin-Induced Asthma in Mice

Kim, M. R., Bashir, K. M. I., Lee, J., Ku, M.-U., Kim, J. W., Kim, K.-Y., Shin, S. K., Hong, E.-J., Ku, S., & Choi, J. (2023) · Applied Sciences · doi:10.3390/app13169342 · Cited by 7

Tumor suppressive pathways in the control of neurogenesis

Bartesaghi, S., & Salomoni, P. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1063-9 · Cited by 8

AGAP2-AS1 May Promote the Occurrence and Development of Glioblastoma by Sponging miR-9-5p: Evidence From a ceRNA Network

Luo, X., Tu, T., Zhong, Y., Xu, S., Chen, X., Chen, L., & Yang, F. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.607989 · Cited by 7

Cancer stem cell phosphatases

Momeny, M., Arsiola, T., & Westermarck, J. K. (2021) · Biochemical Journal · doi:10.1042/bcj20210254 · Cited by 6

Bibliometric analysis of PTEN in neurodevelopment and neurodegeneration

Zhang, Y., Tan, Y.-T., Wang, M., Li, L., Huang, J.-F., & Wang, S. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1390324 · Cited by 6

Exercise intervention may play a potential therapeutic role in patients with glioblastoma multiforme (Review)

Sharif, S. A. I., Harman, N., Hydock, D. S., & Olson, T. P. (2024) · World Academy of Sciences Journal · doi:10.3892/wasj.2024.256 · Cited by 6

Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes

Roy, S. A. B. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i14.1579 · Cited by 6

Multimodal spatially resolved near-field scattering and absorption spectroscopy

Ostertag, E., Merz, T., & Kessler, R. W. (2012) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.909086 · Cited by 6

MicroRNAs in Brain Tumors

Spence, T., Nguyen, J., Bouffet, É., & Huang, A. (2010) · Springer eBooks · doi:10.1007/978-94-007-0298-1_15 · Cited by 6

Driver or passenger effects of augmented c-Myc and Cdc20 in gliomagenesis

Ji, P., Zhou, X., Liu, Q., Fuller, G. N., Phillips, L. M., & Zhang, W. (2016) · Oncotarget · doi:10.18632/oncotarget.8080 · Cited by 6

The role of the PIK3CA gene in the development and aging of the brain

Xie, S.-Z., Ni, J., Guo, H., Luu, V., Wang, Y., Zhao, J. J., & Roberts, T. (2021) · Scientific Reports · doi:10.1038/s41598-020-79416-6 · Cited by 6

Gliomas and brain lymphomas in HIV-1/AIDS patients: reflections from a 20-year follow up in Mexico and Brazil

Cedeno‐Laurent, F., & Trujillo, J. R. (2011) · Microbiology Research · doi:10.4081/mr.2011.e11 · Cited by 6

Correction: Akt and c-Myc Induce Stem-Cell Markers in Mature Primary p53−/−Astrocytes and Render These Cells Gliomagenic in the Brain of Immunocompetent Mice

Radke, J., Bortolussi, G., & Pagenstecher, A. (2013) · PLoS ONE · doi:10.1371/annotation/562d2594-464f-49f1-90ef-f78cafcd3956 · Cited by 6

Region-Specific Human Brain Organoids Reveal Synaptic and Cell State Drivers of Glioblastoma InvasionPreprint

Bhatia, T. N., Ganta, S., Meselhe, M., Sojka, C., Martija, A. A., Nieland, L., Rufen-Blanchette, U., Sing, A., King, A. T., Hub, B. O., et al. (2025) · SSRN Electronic Journal · doi:10.1101/2025.10.15.682580 · Cited by 6

Genome-wide 5-hydroxymethylcytosine (5hmC) reassigned in Pten-depleted mESCs along neural differentiation

Wang, Z., Miu, K.-K., Chan, S.-W., Ou, F., Law, P. W. N., & Chan, W. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.956604 · Cited by 5

Effectiveness of Immature Asian Pear Extract on Pulmonary Injury Caused by Particulate Matter in Mice

Kim, M., Lee, J., Ku, M.-U., Kim, K.-Y., Shin, S. K., Hong, E.-J., Ku, S., & Choi, J. (2023) · Applied Sciences · doi:10.3390/app13179578 · Cited by 5

A potassium‐chloride co‐transporter with altered genome architecture functions as a suppressor in glioma

Liu, H., Pan, Z., Lin, X., Chen, L., Yang, Q., Zhang, W., Dai, L., Zhang, Y., Li, W., Chen, Y., et al. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.18352 · Cited by 5

Comprehensive analysis reveals PLK3 as a promising immune target and prognostic indicator in glioma

QIAN, A., Wang, X., Huo, G., CHEN, S., Gong, R., Zhu, T., Zhao, C., Lu, F., & Qiao, L. (2024) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.32604/or.2024.050794 · Cited by 6

Rodent models of tumours of the central nervous system

Brandner, S. (2024) · Molecular Oncology · doi:10.1002/1878-0261.13729 · Cited by 5

Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models

Schoof, M., Zheng, T., Sill, M., Imle, R., Cais, A., Altendorf, L., Fürst, A., Hofmann, N., Ernst, K., Vonficht, D., et al. (2025) · Nature Genetics · doi:10.1038/s41588-025-02419-4 · Cited by 5

Biobanking: An Important Resource for Precision Medicine in Glioblastoma

Tan, M. S. Y., Sandanaraj, E., Tang, C., & Ang, B. T. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-45457-3_4 · Cited by 5

A novel approach to glioblastoma multiforme treatment using modulation of key pathways by naturally occurring small molecules

Afshari, A. R., Sanati, M., Aminyavari, S., Keshavarzi, Z., Ahmadi, S. S., Oroojalian, F., Karav, S., & Sahebkar, A. (2025) · Inflammopharmacology · doi:10.1007/s10787-025-01666-5 · Cited by 6

Glioma Models: New GEMMs Add “Class” with Genomic and Expression Correlations

Maire, C. L., & Ligon, K. L. (2011) · Cancer Cell · doi:10.1016/j.ccr.2011.02.018 · Cited by 5

Tumor stem cells from glioblastoma multiforme

Никифорова, З. Н., Kudryavtsev, I. A., Arnotskaya, N. E., Bryukhovetskiy, I., & Шевченко, В. Е. (2016) · Advances in molecular oncology · doi:10.17650/2313-805x.2016.3.2.26-33 · Cited by 5

Enhanced cued fear memory following post-training whole body irradiation of 3-month-old mice

Olsen, R. H. J., Weber, S. J., Akinyeke, T. O., & Raber, J. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.11.031 · Cited by 6

IDP-410: a Novel Therapeutic Peptide that Alters N-MYC Stability and Reduces Angiogenesis and Tumor Progression in Glioblastomas

Gargini, R., Segura‐Collar, B., Garranzo‐Asensio, M., Hortigüela, R., Iglesias-Hernández, P., Lobato-Alonso, D., Moreno-Raja, M., Esteban-Martín, S., Sepúlveda-Sánchez, J. M., Nevola, L., et al. (2022) · Neurotherapeutics · doi:10.1007/s13311-021-01176-6 · Cited by 5

Patient-Derived Xenotransplant of CNS Neoplasms in Zebrafish: A Systematic Review

Sarmiento, B. E., Callegari, S., Ghotme, K. A., & Akle, V. (2022) · Cells · doi:10.3390/cells11071204 · Cited by 5

Relationship between phosphatase and tensin homolog (PTEN) expression in high grade glioma and histopathologic findings

Hayati, N., Tabriz, H. M., Nazar, E., & Gorji, R. (2021) · Romanian Journal of Neurology · doi:10.37897/rjn.2021.4.7 · Cited by 5

Multiomics Data Analysis and Identification of Immune-Related Prognostic Signatures With Potential Implications in Prognosis and Immune Checkpoint Blockade Therapy of Glioblastoma

Ma, S., Wang, F., Wang, N., Jin, J., Ba, Y., Ji, H., Du, J., & Hu, S. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.886913 · Cited by 5

Glioblastoma multiforme in patients with human immunodeficiency virus: an integrated review and analysis

Valdez, M. J. M., Lu, V. M., Kim, E., Rivas, S. R., Govindarajan, V., Ivan, M. E., Komotar, R. J., Nath, A., Heiss, J. D., & Shah, A. H. (2022) · Journal of Neuro-Oncology · doi:10.1007/s11060-022-04095-4 · Cited by 5

Stemness Activity Underlying Whole Brain Regeneration in a Basal Chordate

Gordon, T., Zaquin, T., Kowarsky, M., Voskoboynik, Y., Hendin, N., Wurtzel, O., Caicci, F., Manni, L., Voskoboynik, A., & Shenkar, N. (2022) · Cells · doi:10.3390/cells11233727 · Cited by 5

The multifaceted role of quaking protein in neuropsychiatric disorders and tumor progression

Guo, Z., Liu, B., Wei, Y. J., Wang, H., Zhang, Q., & Hong, X. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1341114 · Cited by 5

Deciphering the topological landscape of glioma using a network theory framework

Yao, M.-C., Su, Y., Xiong, R., Zhang, X., Zhu, X., Chen, Y.-C., & Ao, P. (2024) · Scientific Reports · doi:10.1038/s41598-024-77856-y · Cited by 4

Emerging Concepts in Neuro-Oncology

Sciuscio, D., & Hegi, M. E. (2012) · Springer eBooks · doi:10.1007/978-0-85729-458-6 · Cited by 5

Soluble Guanylate Cyclase β1 Subunit Represses Human Glioblastoma Growth

Xiao, H., Zhu, H., Bögler, O., Mónica, F. Z., Kots, A. Y., Murad, F., & Bian, K. (2023) · Cancers · doi:10.3390/cancers15051567 · Cited by 4

Taking advantage of neural development to treat glioblastoma

Zhang, Z., & Lin, C.-C. J. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12655 · Cited by 4

Oxidative Phosphorylation (OXPHOS) Promotes the Formation and Growth of Melanoma Lung and Brain MetastasesPreprint

Guerrieri, R. A., Fischer, G. M., Kircher, D. A., Joon, A. Y., Cortez, J., Grossmann, A. H., Hudgens, C. W., Ledesma, D. A., Lazcano, R., Onana, C. Y. B., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.23.633049 · Cited by 4

l-2-Hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression

Gu, W., Wang, X., Solmonson, A., Cai, L., Xiao, Y., Tasdogan, A., Franklin, J., Zhang, Y., Zhang, H., Westfall, A. K., et al. (2026) · Journal of Clinical Investigation · doi:10.1172/jci197010 · Cited by 3

Stem Cells in Brain Tumour Development and Therapy- Two-Sides of the Same Coin

Lee, C., Dunn, S. E., & Yip, S. S. F. (2012) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100013159 · Cited by 3

Modeling genetic mosaicism of the mammalian target of rapamycin pathway in the cerebral cortex

Feliciano, D. M. (2023) · Frontiers in Mammal Science · doi:10.3389/fmamm.2023.1231778 · Cited by 3

Deciphering the role of transcription factors in glioblastoma cancer stem cells

Li, K., Li, H., He, A., Zhang, G., Jin, Y., Cai, J., Ye, C., Qi, L., & Liu, Y. (2024) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2024061 · Cited by 3

Comprehensive gene set enrichment and variation analyses identify SUV39H1 as a potential prognostic biomarker for glioblastoma immunorelevance

Liu, J., Luo, Q., Zhao, H., Yang, M., Yang, J., Wang, Y., Zhao, M., Mao, J., Chen, J., Guo, B., et al. (2024) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2024.11.016 · Cited by 3

The Impact of Neural Stem Cell Biology on CNS Carcinogenesis and Tumor Types

Kurian, K. M. (2011) · Pathology Research International · doi:10.4061/2011/685271 · Cited by 3

E3 ubiquitin-ligase RNF138 may regulate p53 protein expression to regulate the self-renewal and tumorigenicity of glioma stem cells

Chao, Q., Li, X., & Huang, Y. (2023) · Journal of Cancer Research and Therapeutics · doi:10.4103/jcrt.jcrt_733_23 · Cited by 3

PTEN pathogenic variants are associated with poor prognosis in patients with advanced soft tissue sarcoma

Pan, M., Zhou, M. Y., Jiang, C., Zhang, Z., Bui, N. Q., Bien, J. Y., Siy, A., Achacoso, N. S., Solorzano, A. V., Tse, P., et al. (2024) · BJC Reports · doi:10.1038/s44276-023-00029-3 · Cited by 3

Haploinsufficiency of Adenomatous Polyposis Coli Coupled with Kirsten Rat Sarcoma Viral Oncogene Homologue Activation and P53 Loss Provokes High-Grade Glioblastoma Formation in Mice

Fang, K.-T., Su, C.-S., Layos, J. J., Lau, N. Y. S., & Cheng, K. (2024) · Cancers · doi:10.3390/cancers16051046 · Cited by 3

Genetics and Biology of Glioblastoma Multiforme

do Carmo, A., Crespo, I., & Celeste, M. G. (2011) · InTech eBooks · doi:10.5772/23479 · Cited by 3

Multimodality Targeting of Glioma Cells

He, Z., Mitteer, R. A., Mou, Y., & Fan, Y. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-47660-7.00005-7 · Cited by 3

Intratumor Heterogeneity and Transcriptional Profiling in Glioblastoma: Translational Opportunities

Piccirillo, S. G. M., & Spiteri, I. (2015) · Future Neurology · doi:10.2217/fnl.15.16 · Cited by 3

Pten and p53 Converge on c-Myc to Control Differentiation, Self-renewal, and Transformation of Normal and Neoplastic Stem Cells in GlioblastomaPreprint

Zheng, H., Ying, H., Yan, H., Kimmelman, A. C., Hiller, D. J., Chen, A.-J., Perry, S. R., Tonon, G., Chu, G. C., Ding, Z., et al. (2008) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2008.73.047 · Cited by 122

Stop acting so immature

Seton-Rogers, S. E. (2008) · Nature reviews. Cancer · doi:10.1038/nrc2546

Inactivation of Pten cooperating with p53 loss induces malignant gliomas

Zheng, H., Ying, H., Kimmelman, A. C., Yang, H., Chen, A.-J., Perry, S. R., Chu, G. C., Ding, J., Ligon, K. L., Wiedemeyer, R., et al. (2008) · Cancer Research

Pancreas and Biliary Tree

(2016) · Modern Pathology · doi:10.1038/modpathol.2016.19 · Cited by 3

Abstract 353: Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc.

Kim, H. (2013) · Cancer Research · doi:10.1158/1538-7445.am2013-353