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GABA Binding to an Insect GABA Receptor: A Molecular Dynamics and Mutagenesis Study

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The Color of Cation-π Interactions: Subtleties of Amine-Tryptophan Interaction Energetics Allow for Radical-like Visible Absorbance and Fluorescence

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The Unique α4(+)/(−)α4 Agonist Binding Site in (α4)3(β2)2 Subtype Nicotinic Acetylcholine Receptors Permits Differential Agonist Desensitization Pharmacology versus the (α4)2(β2)3 Subtype

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A Miniature Protein Stabilized by a Cation−π Interaction Network

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Pod-mod vs. conventional e-cigarettes: nicotine chemistry, pH, and health effects

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Discovery of Novel Pyrazole–Quinazoline-2,4-dione Hybrids as 4‑Hydroxyphenylpyruvate Dioxygenase Inhibitors

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Cation−π Interactions and Their Contribution to Mussel Underwater Adhesion Studied Using a Surface Forces Apparatus: A Mini-Review

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Two Neuronal Nicotinic Acetylcholine Receptors, α4β4 and α7, Show Differential Agonist Binding Modes

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Recent Developments in Novel Antidepressants Targeting α4β2-Nicotinic Acetylcholine Receptors

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Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of 3 4 Nicotinic Receptor

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Die Kation‐π‐Wechselwirkung in der Katalyse mit niedermolekularen Verbindungen

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Unexpectedly Enhanced Solubility of Aromatic Amino Acids and Peptides in an Aqueous Solution of Divalent Transition-Metal Cations

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Novel 2D CaCl crystals with metallicity, room-temperature ferromagnetism, heterojunction, piezoelectricity-like property and monovalent calcium ions

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Functional Probes of Drug–Receptor Interactions Implicated by Structural Studies: Cys-Loop Receptors Provide a Fertile Testing Ground

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Discovery of (2S,3R)-N-[2-(Pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]benzo[b]furan-2-carboxamide (TC-5619), a Selective α7 Nicotinic Acetylcholine Receptor Agonist, for the Treatment of Cognitive Disorders

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Insights into the Neurobiology of the Nicotinic Cholinergic System and Nicotine Addiction from Mice Expressing Nicotinic Receptors Harboring Gain-of-Function Mutations

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In Vivo Incorporation of Non‐canonical Amino Acids by Using the Chemical Aminoacylation Strategy: A Broadly Applicable Mechanistic Tool

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Quantitative Assessment of Substituent Effects on Cation−π Interactions Using Molecular Electrostatic Potential Topography

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Molecular Determinants for Competitive Inhibition of α4β2 Nicotinic Acetylcholine Receptors

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A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists

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Structural Basis of Activation of Cys-Loop Receptors: the Extracellular–Transmembrane Interface as a Coupling Region

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Incorporation of Non-Canonical Amino Acids

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Mutual Influence between Halogen Bonds and Cation–π Interactions: A Theoretical Study

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Identifying Key Amino Acid Residues That Affect α-Conotoxin AuIB Inhibition of α3β4 Nicotinic Acetylcholine Receptors

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Synthesis and biological activities of indolizine derivatives as alpha-7 nAChR agonists

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The Energy and Work of a Ligand-Gated Ion Channel

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Lynx Prototoxins: Roles of Endogenous Mammalian Neurotoxin-Like Proteins in Modulating Nicotinic Acetylcholine Receptor Function to Influence Complex Biological Processes

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Contribution of Subunits to Caenorhabditis elegans Levamisole-Sensitive Nicotinic Receptor Function

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Unorthodox Combination of Cation−π and Charge-Transfer Interactions within a Donor–Acceptor Pair

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Structure-Based Design of Highly Selective Inhibitors of the CREB Binding Protein Bromodomain

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Human brain imaging of nicotinic acetylcholine α4β2* receptors using [18 F ] N ifene: Selectivity, functional activity, toxicity, aging effects, gender effects, and extrathalamic pathways

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Strong Co-Ion Effect via Cation−π Interaction on the Self-Assembly of Metal–Organic Cationic Macrocycles

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Dennis Dougherty

(2009) · Nature · doi:10.1038/7237384a

Macmillan Publishers Limited. The work described in this chapter concerning

Blum, A. P., Nakamura, D. T., & Shanata, J. A. P. (2014)

Probing binding interactions of agonists at a nicotinic acetylcholine receptor subtype important to addiction and Parkinson's disease

Post, M. R., Lester, H. A., & Dougherty, D. A. (2016) · CaltechAUTHORS (California Institute of Technology)

Nicotinic pharmacophore: The pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH

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Variations in Binding Among Several Agonists at Two Stoichiometries of the Neuronal, α4β2 Nicotinic Receptor

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