The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
The Amphimedon queenslandica genome and the evolution of animal complexity
Open accessAbstract
Sponges are an ancient group of animals that diverged from other metazoans over 600 million years ago. Here we present the draft genome sequence of Amphimedon queenslandica, a demosponge from the Great Barrier Reef, and show that it is remarkably similar to other animal genomes in content, structure and organization. Comparative analysis enabled by the sequencing of the sponge genome reveals genomic events linked to the origin and early evolution of animals, including the appearance, expansion and diversification of pan-metazoan transcription factor, signalling pathway and structural genes. This diverse 'toolkit' of genes correlates with critical aspects of all metazoan body plans, and comprises cell cycle control and growth, development, somatic- and germ-cell specification, cell adhesion, innate immunity and allorecognition. Notably, many of the genes associated with the emergence of animals are also implicated in cancer, which arises from defects in basic processes associated with metazoan multicellularity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“scaffold-level genome assemblies revealed surprising syntenic conservation over hundreds of millions of years of evolution, spanning the divergence between cnidarians, chordates, sponges, and placozoans”
From Topological Approaches in Animal Comparative Genomics (2026) · cites this paper as [37]
The cited source says what the claim attributes to it.
In the citing paper
“Genome sequences of some animal clades very distantly related to humans, including sponges (37), placozoans (flat animals) (38), and cnidarians (i.e., true jellyfish, corals) (39, 40), suggested that many genes thought to define vertebrates were, in fact, present even in earlier ancestral animals”
From Topological Approaches in Animal Comparative Genomics (2026) · cites this paper as [37]
In the citing paper
“Sequencing of the demosponge genome Amphimedon queenslandica [32] and multiple transcriptomes from all major sponge lineages [33] have revealed a remarkable number of genes present in sponges that are associated with neural cell types in bilaterians and cnidarians.”
From Where is my mind? How sponges and placozoans may have lost neural cell types (2015) · cites this paper as [32]
In the citing paper
“Sponges are said to lack true neural cell types [31], yet these animals have genes associated with neurons, behaviours indicating sensing of external stimuli, and secretory cells involved in sensory behaviour that express neural genes.”
From Where is my mind? How sponges and placozoans may have lost neural cell types (2015) · cites this paper as [32]
In the citing paper
“most of the structural components of the post-synaptic density (PSD) are present in the sponge Amphimedon [22,28], and some have clear homologs in choanoflagellates and other unicellular holozoans [29,30]”
From Back to the Basics: Cnidarians Start to Fire (2017) · cites this paper as [22]
In the citing paper
“an extensive set of genomic and transcriptomic databases is becoming available for several sponge species -Amphimedon queenslandica, Oscarella carmela and Sycon ciliatum, as well as for a placozoan Trichoplax adhaerens [22–25]”
From Back to the Basics: Cnidarians Start to Fire (2017) · cites this paper as [22]
In the citing paper
“Although neurosecretory systems have deep ancestry in metazoan evolution [1,2], it is more probable that the first neurons with fast electrical signal propagation to evolve were controlling animal locomotion.”
From Origin and early evolution of neural circuits for the control of ciliary locomotion (2011) · cites this paper as [1]
In the citing paper
“Even if a local release of transmitters is possible in sponges, the effects of such signal transmission can only be local, since sponges have no gap junctions and no axons [1].”
From Origin and early evolution of neural circuits for the control of ciliary locomotion (2011) · cites this paper as [1]
In the citing paper
“These GPCRs originated by lineage-specific expansion, and many are single-exon genes forming clusters in the genome [1], reminiscent of lineage-specific putative chemosensory GPCRs in other animal groups [43].”
From Origin and early evolution of neural circuits for the control of ciliary locomotion (2011) · cites this paper as [1]
In the citing paper
“The sponge genome contains genes coding for neuropeptide processing enzymes and synaptic vesicle release proteins, however no neuropeptides have been identified [1].”
From Origin and early evolution of neural circuits for the control of ciliary locomotion (2011) · cites this paper as [1]
In the citing paper
“The presence of approximately 130 rhodopsin-family G-protein coupled receptors (GPCRs) in the sponge genome also suggests the use of chemosensation [1].”
From Origin and early evolution of neural circuits for the control of ciliary locomotion (2011) · cites this paper as [1]
In the citing paper
“Importantly, the developmental gene toolkit of sponges is surprisingly similar to the eumetazoan toolkit, although information on its expression remains limited 4,7 .”
From Developmental gene expression provides clues to relationships between sponge and eumetazoan body plans (2014) · cites this paper as [7]
In the citing paper
“One of the three Amphimedon Wnt ligands is specifically expressed in the posterior pole of the embryos and larvae, and one of the eight Amphimedon Tgfb ligands is expressed in the outer embryonic layer, and then restricted to the posterior pole 7,48 .”
From Developmental gene expression provides clues to relationships between sponge and eumetazoan body plans (2014) · cites this paper as [7]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Thompson, J. D., Higgins, D. G., & Gibson, T. J. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.22.4673 · Cited by 64,617
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219
MrBayes 3: Bayesian phylogenetic inference under mixed models
Ronquist, F., & Huelsenbeck, J. P. (2003) · Bioinformatics · doi:10.1093/bioinformatics/btg180 · Cited by 29,194
MRBAYES: Bayesian inference of phylogenetic trees.
Huelsenbeck, J. P., & Ronquist, F. (2001) · Bioinformatics · doi:10.1093/bioinformatics/17.8.754 · Cited by 21,937
A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood
Guindon, S., & Gascuel, O. (2003) · Systematic Biology · doi:10.1080/10635150390235520 · Cited by 16,923
Selection of Conserved Blocks from Multiple Alignments for Their Use in Phylogenetic Analysis
Castresana, J. (2000) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026334 · Cited by 10,681
Korf, I. F. (2004) · BMC Bioinformatics · doi:10.1186/1471-2105-5-59 · Cited by 3,228
The Pfam protein families database
Bateman, A. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh121 · Cited by 3,127
PANTHER: A Library of Protein Families and Subfamilies Indexed by FunctionPreprint
Thomas, P. D., Campbell, M. J., Kejariwal, A., Mi, H., Karlak, B., Daverman, R., Diemer, K., Muruganujan, A., & Narechania, A. (2003) · Genome Research · doi:10.1101/gr.772403 · Cited by 2,978
TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing
Schmidt, H. A., Strimmer, K., Vingron, M., & von Haeseler, A. (2002) · Bioinformatics · doi:10.1093/bioinformatics/18.3.502 · Cited by 2,512
Flagged first, then by citations
Research works printed but not linked: 5
- Grant, R. E. Animal Kingdom. in The Cyclopaedia of Anatomy and Physiology, Vol. 1 (ed. Todd, R. B.) (Sherwood-Gilbert-Piper, 1836)
- Sollas, W. J. Report on the Tetractinellida collected by H.M.S. Challenger, during the years 1873–1876. in Report on the Scientific Results of the Voyage of H.M.S. Challenger During the Years 1873–76 (Neill and Company, 1888)
- Hyman, L. H. The Invertebrates, Vol. 1 Protozoa through Ctenophora (McGraw-Hill, 1940)
- Felsenstein, J. PHYLIP–Phylogeny Inference Package (Version 3.2). Cladistics 5, 164–166 (1989)
- Team, R. D. C. R: A Language and Environment for Statistical Computing (R Foundation for Statistical Computing, 2009)
Cited by
Sorted by citations
Items 201–300 of 999
Improving animal phylogenies with genomic data
Telford, M. J., & Copley, R. R. (2011) · Trends in Genetics · doi:10.1016/j.tig.2011.02.003 · Cited by 77
Correlating structure and function during the evolution of fibrinogen‐related domains
Doolittle, R. F., McNamara, K., & Lin, K. (2012) · Protein Science · doi:10.1002/pro.2177 · Cited by 76
Senatore, A., Raiss, H., & Le, P. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00481 · Cited by 77
Anteroposterior axis patterning by early canonical Wnt signaling during hemichordate development
Darras, S., Fritzenwanker, J. H., Uhlinger, K. R., Farrelly, E. R., Pani, A. M., Hurley, I. A., Norris, R. P., Osovitz, M., Terasaki, M., Wu, M., et al. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2003698 · Cited by 75
Adams, E. D. M., Goss, G. G., & Leys, S. P. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015040 · Cited by 74
Self-citationWhere is my mind? How sponges and placozoans may have lost neural cell types
Ryan, J. F., & Chiodin, M. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2015.0059 · Cited by 73
Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation
DuBuc, T. Q., Stephenson, T. B., Rock, A. Q., & Martindale, M. Q. (2018) · Nature Communications · doi:10.1038/s41467-018-04184-x · Cited by 73
Questioning the evidence of organic compounds called sponge biomarkers
Antcliffe, J. B. (2013) · Palaeontology · doi:10.1111/pala.12030 · Cited by 72
Origin and evolution of plexins, semaphorins, and Met receptor tyrosine kinases
Junqueira Alves, C., Yotoko, K., Zou, H., & Friedel, R. H. (2019) · Scientific Reports · doi:10.1038/s41598-019-38512-y · Cited by 72
The genetic factors of bilaterian evolution
Heger, P., Zheng, W. L., Rottmann, A., Panfilio, K. A., & Wiehe, T. (2020) · eLife · doi:10.7554/elife.45530 · Cited by 76
New genomic data and analyses challenge the traditional vision of animal epithelium evolution
Belahbib, H., Renard, E., Santini, S., Jourda, C., Claverie, J.-M., Borchiellini, C., & Le Bivic, A. (2018) · BMC Genomics · doi:10.1186/s12864-018-4715-9 · Cited by 71
Evolution: Ctenophore Genomes and the Origin of Neurons
Marlow, H., & Arendt, D. (2014) · Current Biology · doi:10.1016/j.cub.2014.06.057 · Cited by 71
Novel scenarios of early animal evolution--is it time to rewrite textbooks?
Dohrmann, M., & Worheide, G. (2013) · Integrative and Comparative Biology · doi:10.1093/icb/ict008 · Cited by 71
Gauthier, M.-E. A., Watson, J. R., & Degnan, S. M. (2016) · Frontiers in Marine Science · doi:10.3389/fmars.2016.00196 · Cited by 71
Self-citationThe Comb Jelly Opsins and the Origins of Animal Phototransduction
Feuda, R., Rota-Stabelli, O., Oakley, T. H., & Pisani, D. (2014) · Genome Biology and Evolution · doi:10.1093/gbe/evu154 · Cited by 70
Self-citationZhang, W., MITCHELL, L. A., Bader, J. S., & Boeke, J. D. (2020) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-013118-110704 · Cited by 71
Conditional deletion of N‐Myc disrupts neurosensory and non‐sensory development of the ear
Kopecky, B. J., Santi, P. A., Johnson, S. B., Schmitz, H. M., & Fritzsch, B. (2011) · Developmental Dynamics · doi:10.1002/dvdy.22620 · Cited by 70
Toll-like receptors: an overview from invertebrates to vertebrates
Coscia, M. R., Giacomelli, S., & Oreste, U. (2011) · Invertebrate survival journal · Cited by 69
Losing Complexity: The Role of Simplification in Macroevolution.
O'Malley, M. A., Wideman, J. G., & Ruiz-Trillo, I. (2016) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2016.04.004 · Cited by 64
Chang, S., Feng, Q., Clausen, S., & Zhang, L. (2016) · Palaeogeography Palaeoclimatology Palaeoecology · doi:10.1016/j.palaeo.2016.06.032 · Cited by 71
Taxonomic and Functional Microbial Signatures of the Endemic Marine Sponge Arenosclera brasiliensis
Silva, A. E. T., Rua, C. P. J., Silva, A. E. T., Dutilh, B. E., Moreira, A. P. B., Edwards, R. A., Hajdu, E., Lôbo‐Hajdu, G., de Vasconcelos, A. T. R., Berlinck, R. G. S., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039905 · Cited by 70
Lavrov, A., & Kosevich, I. A. (2016) · Journal of Experimental Zoology Part A Ecological Genetics and Physiology · doi:10.1002/jez.2006 · Cited by 69
Glycoprotein Hormones and Their Receptors Emerged at the Origin of Metazoans
Roch, G. J., & Sherwood, N. M. (2014) · Genome Biology and Evolution · doi:10.1093/gbe/evu118 · Cited by 69
Conservation of Planar Polarity Pathway Function Across the Animal Kingdom
Hale, R., & Strutt, D. I. (2015) · Annual Review of Genetics · doi:10.1146/annurev-genet-112414-055224 · Cited by 73
Ueda, N., Richards, G. S., Degnan, B. M., Kranz, A. M., Adamska, M., Croll, R. P., & Degnan, B. M. (2016) · Scientific Reports · doi:10.1038/srep37546 · Cited by 75
Self-citationNon-canonical Notch signaling represents an ancestral mechanism to regulate neural differentiation
Layden, M. J., & Martindale, M. Q. (2014) · EvoDevo · doi:10.1186/2041-9139-5-30 · Cited by 68
A cnidarian homologue of an insect gustatory receptor functions in developmental body patterning
Saina, M., Busengdal, H., Sinigaglia, C., Petrone, L., Oliveri, P., Rentzsch, F., & Benton, R. (2015) · Nature Communications · doi:10.1038/ncomms7243 · Cited by 68
Premetazoan Ancestry of the Myc–Max Network
Young, S. L., Diolaiti, D., Conacci‐Sorrell, M., Ruiz‐Trillo, I., Eisenman, R. N., & King, N. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr132 · Cited by 65
Emerging Sponge Models of Animal-Microbe Symbioses
Pita, L., Fraune, S., & Hentschel, U. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.02102 · Cited by 70
The Evolution of the Hallmarks of Aging
Lemoine, M. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.693071 · Cited by 76
Jager, M., Dayraud, C., Mialot, A., Quéinnec, É., Guyader, H. L., & Manuel, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0084363 · Cited by 74
Insights into the early evolution of animal calcium signaling machinery: A unicellular point of view
Cai, X., Wang, X., Patel, S., & Clapham, D. E. (2014) · Cell Calcium · doi:10.1016/j.ceca.2014.11.007 · Cited by 66
Complex Homology and the Evolution of Nervous Systems
Liebeskind, B. J., Hillis, D. M., Zakon, H. H., & Hofmann, H. A. (2015) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2015.12.005 · Cited by 72
Bacterial Influences on Animal OriginsPreprint
Alegado, R. ʻ., & King, N. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016162 · Cited by 70
Riesgo, A., Pérez-Porro, A. R., Carmona, S., Leys, S. P., & Giribet, G. (2011) · Molecular Ecology Resources · doi:10.1111/j.1755-0998.2011.03097.x · Cited by 66
Self-citationPita, L., Hoeppner, M. P., Ribes, M., & Hentschel, U. (2018) · Scientific Reports · doi:10.1038/s41598-018-34330-w · Cited by 69
Neuronal coordination of motile cilia in locomotion and feeding
Marinković, M., Berger, J., & Jékely, G. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0165 · Cited by 67
Posadas, N., Baquiran, J. I., Nada, M. A., Kelly, M., & Conaco, C. (2021) · The ISME Journal · doi:10.1038/s41396-021-01050-5 · Cited by 65
Self-citationWhat sponges can tell us about the evolution of developmental processes
Adamska, M., Degnan, B. M., Green, K., & Zwafink, C. (2011) · Zoology · doi:10.1016/j.zool.2010.10.003 · Cited by 65
Self-citationKerner, P., Degnan, B. M., Marchand, L., Degnan, B. M., & Vervoort, M. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr046 · Cited by 70
Self-citationTyrosine kinase signaling and the emergence of multicellularity
Miller, W. T. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2012.03.009 · Cited by 69
Eßer, C., Kuhn, A., Groth, G., Lercher, M. J., & Maurino, V. G. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu041 · Cited by 64
Evolution of the lamin protein family
Peter, A., & Stick, R. (2012) · Nucleus · doi:10.4161/nucl.18927 · Cited by 68
Mollo, E., Fontana, A., Roussis, V., Polese, G., Amodeo, P., & Ghiselin, M. T. (2014) · Frontiers in Chemistry · doi:10.3389/fchem.2014.00092 · Cited by 64
Voigt, O., Adamski, M., Sluzek, K., & Adamska, M. (2014) · BMC Evolutionary Biology · doi:10.1186/s12862-014-0230-z · Cited by 63
Self-citationSymbiont transmission in marine sponges: reproduction, development, and metamorphosis
Carrier, T. J., Maldonado, M., Schmittmann, L., Pita, L., Bosch, T. C. G., & Hentschel, U. (2022) · BMC Biology · doi:10.1186/s12915-022-01291-6 · Cited by 61
Dynamic and Widespread lncRNA Expression in a Sponge and the Origin of Animal Complexity
Gaiti, F., Fernández-Valverde, S. L., Nakanishi, N., Calcino, A., Yanai, I., Tanurdžić, M., & Degnan, B. M. (2015) · Molecular Biology and Evolution · doi:10.1093/molbev/msv117 · Cited by 64
Self-citationEreskovsky, A. V., Renard, E., & Borchiellini, C. (2012) · Development Genes and Evolution · doi:10.1007/s00427-012-0399-3 · Cited by 62
Fatal Attraction: How Bacterial Adhesins Affect Host Signaling and What We Can Learn from Them
Stones, D. H., & Krachler, A. M. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16022626 · Cited by 63
Erives, A. J., & Fassler, J. S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0117192 · Cited by 64
Cophylogeny and convergence shape holobiont evolution in sponge–microbe symbioses
Pankey, M. S., Plachetzki, D. C., Macartney, K. J., Gastaldi, M., Slattery, M., Gochfeld, D. J., & Lesser, M. P. (2022) · Nature Ecology & Evolution · doi:10.1038/s41559-022-01712-3 · Cited by 62
Self-citationBTB domains: A structural view of evolution, multimerization, and protein–protein interactions
Bonchuk, A. N., Balagurov, K., & Georgiev, P. G. (2022) · BioEssays · doi:10.1002/bies.202200179 · Cited by 66
Rivera, A. S., Hammel, J. U., Haen, K. M., Danka, E. S., Cieniewicz, B., Winters, I. P., Posfai, D., Wörheide, G., Lavrov, D. V., Knight, S. W., et al. (2011) · BMC Biotechnology · doi:10.1186/1472-6750-11-67 · Cited by 61
Sponge cell reaggregation: Mechanisms and dynamics of the process
Lavrov, A., & Kosevich, I. A. (2014) · Russian Journal of Developmental Biology · doi:10.1134/s1062360414040067 · Cited by 61
Functionalization of a protosynaptic gene expression network
Conaco, C., Bassett, D. S., Zhou, H., Arcila, M. L., Degnan, B. M., Degnan, B. M., & Kosik, K. S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1201890109 · Cited by 60
Self-citationOrigin and Evolution of Laminin Gene Family Diversity
Fahey, B., & Degnan, B. M. (2012) · Molecular Biology and Evolution · doi:10.1093/molbev/mss060 · Cited by 61
Self-citationEvolution of ligands, receptors and metabolizing enzymes of thyroid signaling
Holzer, G., Roux, N., & Laudet, V. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.03.021 · Cited by 62
Moroz, L. L., & Kohn, A. B. (2015) · Integrative and Comparative Biology · doi:10.1093/icb/icv104 · Cited by 61
The origin and evolution of synaptic proteins – choanoflagellates lead the way
Burkhardt, P. (2015) · Journal of Experimental Biology · doi:10.1242/jeb.110247 · Cited by 59
Molecular Evolution and Structural Features of IRAK Family Members
Gosu, V., Basith, S., Durai, P., & Choi, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049771 · Cited by 59
Integrin-mediated uptake of fibronectin-binding bacteria
Hoffmann, C., Ohlsen, K., & Hauck, C. R. (2011) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2011.03.001 · Cited by 59
Transcriptome Analysis of the Scleractinian Coral Stylophora pistillata
Karako‐Lampert, S., Zoccola, D., Salmon‐Divon, M., Katzenellenbogen, M., Tambutté, S., Bertucci, A., Hoegh‐Guldberg, O., Deleury, E., Allemand, D., & Levy, O. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088615 · Cited by 60
Mass spectrometry of short peptides reveals common features of metazoan peptidergic neurons
Hayakawa, E., Guzman, C., Horiguchi, O., Kawano, C., Shiraishi, A., Mohri, K., Lin, M., Nakamura, R., Nakamura, R., Kawai, E., et al. (2022) · Nature Ecology & Evolution · doi:10.1038/s41559-022-01835-7 · Cited by 58
Degnan, S. M. (2014) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2014.07.012 · Cited by 58
Self-citationCommunication theory and multicellular biology
Mian, S. I., & Rose, C. (2011) · Integrative Biology · doi:10.1039/c0ib00117a · Cited by 57
Gene Expression Dynamics Accompanying the Sponge Thermal Stress Response
Guzman, C., & Conaco, C. (2016) · PLoS ONE · doi:10.1371/journal.pone.0165368 · Cited by 58
Self-citationOrigin and evolution of the metazoan non-coding regulatory genome
Gaiti, F., Calcino, A., Tanurdžić, M., & Degnan, B. M. (2016) · Developmental Biology · doi:10.1016/j.ydbio.2016.11.013 · Cited by 59
Self-citationMadagascar ground gecko genome analysis characterizes asymmetric fates of duplicated genes
Hara, Y., Takeuchi, M., Kageyama, Y., Tatsumi, K., Hibi, M., Kiyonari, H., & Kuraku, S. (2018) · BMC Biology · doi:10.1186/s12915-018-0509-4 · Cited by 55
A broad‐taxa approach as an important concept in ecotoxicological studies and pollution monitoring
Rosner, A., Ballarin, L., Barnay‐Verdier, S., Borisenko, I., Drago, L., Drobne, D., Eliso, M. C., Harbuzov, Z., Grimaldi, A., Guy‐Haim, T., et al. (2023) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.13015 · Cited by 63
The evolution of animal genomes
Dunn, C. W., & Ryan, J. F. (2015) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2015.08.006 · Cited by 58
Conaco, C., Neveu, P. A., Zhou, H., Arcila, M. L., Degnan, B. M., Degnan, B. M., & Kosik, K. S. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-209 · Cited by 63
Self-citationStructural evolution of cell types by step-wise assembly of cellular modules
Achim, K., & Arendt, D. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2014.05.001 · Cited by 56
Evolution of selenoproteins in the metazoan
Jiang, L., Ni, J., & Liu, Q. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-446 · Cited by 57
Francis, W. R., Eitel, M., Vargas, S., Adamski, M., Haddock, S. H. D., Krebs, S., Blum, H., Erpenbeck, D., & Wörheide, G. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/120998 · Cited by 58
Self-citationBannister, S., Antonova, O., Polo, A., Lohs, C., Hallay, N., Valinciute, A., Raible, F., & Tessmar-Raible, K. (2014) · Genetics · doi:10.1534/genetics.113.161091 · Cited by 56
“(Sodergren et al. 2006; Srivastava et al. 2010; Simakov et al. 2013b).”
BackgroundEvolutionary insights into premetazoan functions of the neuronal protein homer
Burkhardt, P., Grønborg, M., McDonald, K., Sulur, T., Wang, Q., & King, N. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu178 · Cited by 56
De Novo Assembly and Characterization of Four Anthozoan (Phylum Cnidaria) Transcriptomes
Kitchen, S. A., Crowder, C. M., Poole, A. Z., Weis, V. M., & Meyer, E. (2015) · G3 Genes Genomes Genetics · doi:10.1534/g3.115.020164 · Cited by 58
Landing, E., Antcliffe, J. B., Geyer, G., Kouchinsky, A., Bowser, S. S., & Andreas, A. (2018) · Earth-Science Reviews · doi:10.1016/j.earscirev.2018.01.013 · Cited by 55
Krishnan, A., Dnyansagar, R., Almén, M. S., Williams, M. J., Fredriksson, R., Manoj, N., & Schiöth, H. B. (2014) · BMC Evolutionary Biology · doi:10.1186/s12862-014-0270-4 · Cited by 57
Ikmi, A., Gaertner, B., Seidel, C. W., Srivastava, M., Zeitlinger, J., & Gibson, M. C. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu071 · Cited by 55
Self-citationGuo, H., Xian, J.-A., & Wang, A. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.06.059 · Cited by 55
López‐Escardó, D., Grau‐Bové, X., Guillaumet-Adkins, A., Gut, M., Sieracki, M. E., & Ruiz‐Trillo, I. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0088 · Cited by 53
BLIND ordering of large-scale transcriptomic developmental timecourses
Anavy, L., Levin, M., Khair, S., Nakanishi, N., Fernández-Valverde, S. L., Degnan, B. M., & Yanai, I. (2014) · Development · doi:10.1242/dev.105288 · Cited by 54
Self-citationPeptide-gated ion channels and the simple nervous system of Hydra
Gründer, S., & Assmann, M. (2015) · Journal of Experimental Biology · doi:10.1242/jeb.111666 · Cited by 54
Lezama-García, K., Mota‐Rojas, D., Pereira, A. M. F., Martı́nez-Burnes, J., Ghezzi, M. D., Domínguez-Oliva, A., Gómez-Prado, J., Geraldo, A. C. A. P. D. M., Lendez, P. A., Hernández-Ávalos, I., et al. (2022) · Animals · doi:10.3390/ani12010106 · Cited by 53
Abnormal Synaptic Vesicle Biogenesis inDrosophila SynaptogyrinMutants
Stevens, R. J., Akbergenova, Y., Jorquera, R. A., & Littleton, J. T. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2668-12.2012 · Cited by 53
Song, X., Jin, P., Qin, S., Chen, L., & Ma, F. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051657 · Cited by 53
Ghost Loci Imply Hox and ParaHox Existence in the Last Common Ancestor of Animals
Ramos, O. M., Barker, D., & Ferrier, D. E. K. (2012) · Current Biology · doi:10.1016/j.cub.2012.08.023 · Cited by 53
Wilson, J. P., Grotzinger, J. P., Fischer, W. W., Hand, K. P., Jensen, S., Knoll, A. H., Abelson, J. N., Metz, J. M., McLoughlin, N., COHEN, P. A., et al. (2012) · Palaios · doi:10.2110/palo.2011.p11-036r · Cited by 53
An epithelial tissue in Dictyostelium challenges the traditional origin of metazoan multicellularity
Dickinson, D. J., Nelson, W. J., & Weis, W. I. (2012) · BioEssays · doi:10.1002/bies.201100187 · Cited by 62
Li, Z., Wang, Y., He, L., & Zheng, H. (2014) · Scientific Reports · doi:10.1038/srep03895 · Cited by 53
Receptors Mediating Host-Microbiota Communication in the Metaorganism: The Invertebrate Perspective
Dierking, K., & Pita, L. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01251 · Cited by 57
Matters of context guide future research in TGFβ superfamily signaling
Akhurst, R. J., & Padgett, R. W. (2015) · Science Signaling · doi:10.1126/scisignal.aad0416 · Cited by 52
Koutsouveli, V., Cárdenas, P., Santodomingo, N., Marina, A., Morato, E., Rapp, H. T., & Riesgo, A. (2020) · Molecular Biology and Evolution · doi:10.1093/molbev/msaa183 · Cited by 50
Bosch, T. C. G., Adamska, M., Augustin, R., Domazet‐Lošo, T., Forêt, S., Fraune, S., Funayama, N., Grasis, J. A., Hamada, M., Hatta, M., et al. (2014) · BioEssays · doi:10.1002/bies.201400065 · Cited by 52
Self-citationThe rise and fall of TRP-N, an ancient family of mechanogated ion channels, in Metazoa
Schüler, A., Schmitz, G., Reft, A., Özbek, S., Thurm, U., & Bornberg-Bauer, E. (2015) · Genome Biology and Evolution · doi:10.1093/gbe/evv091 · Cited by 51
Nakanishi, N., & Martindale, M. Q. (2018) · eLife · doi:10.7554/elife.39742 · Cited by 48
Diverse and Productive Source of Biopolymer Inspiration: Marine Collagens
Fassini, D., Wilkie, I. C., Pozzolini, M., Ferrario, C., Sugni, M., Rocha, M. S., Giovine, M., Bonasoro, F., Silva, T. H., & Reis, R. L. (2021) · Biomacromolecules · doi:10.1021/acs.biomac.1c00013 · Cited by 51
Tarabichi, M., Antoniou, A., Saiselet, M., Pita, J. M. G., Andry, G., Dumont, J. E., Detours, V., & Maenhaut, C. (2013) · Cancer and Metastasis Reviews · doi:10.1007/s10555-013-9431-y · Cited by 51
Gerdol, M., Venier, P., Edomi, P., & Pallavicini, A. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.01.014 · Cited by 51
Metadata
- Authors
- Srivastava, M., Simakov, O., Chapman, J., Fahey, B., Gauthier, M. E. A., Mitros, T., Richards, G. S., Conaco, C., Dacre, M., Hellsten, U., Larroux, C., Putnam, N. H., Stanke, M., Adamska, M., Darling, A., Degnan, S. M., Oakley, T. H., Plachetzki, D. C., Zhai, Y., Adamski, M., Calcino, A., Cummins, S. F., Goodstein, D. M., Harris, C., Jackson, D. J., Leys, S. P., Shu, S., Woodcroft, B. J., Vervoort, M., Kosik, K. S., Manning, G., Degnan, B. M., & Rokhsar, D. S.
- Affiliations
- University of California, Berkeley (US)
- University of Zurich (CH)
- Joint Genome Institute (US)
- The University of Queensland (AU)
- University of California, Santa Barbara (US)
- Salk Institute for Biological Studies (US)
- Rice University (US)
- University of Göttingen (DE)
- University of California, Davis (US)
- University of Alberta (CA)
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Srivastava, Mansi
- ORCID
- Venue
- Nature
- Published
- 2010-08
- Volume
- 466
- Issue
- 7307
- Pages
- 720-726
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC3130542
- OpenAlex
- W340499956
- Semantic Scholar
- c40c8376e81b11bf8f3e7d04f22db8b3568f06e7
- Cited by
- 1,049
- References
- 60
- Citations by year
- 2026: 22 · 2025: 36 · 2024: 45 · 2023: 56 · 2022: 59 · 2021: 47 · 2020: 51 · 2019: 70 · 2018: 71 · 2017: 60 · 2016: 63 · 2015: 99 · 2014: 85 · 2013: 79 · 2012: 101
- FWCI
- 64.30
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Nature (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion)
- PubMed Central (acceptedVersion)
- QUT ePrints (Queensland University of Technology) (submittedVersion, cc-by-nc-sa)
- ResearchOnline at James Cook University (James Cook University) (submittedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- University of North Texas Digital Library (University of North Texas) (submittedVersion)
- HAL (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- ANU Open Research (Australian National University) (submittedVersion)
- UTS ePRESS (University of Technology Sydney) (submittedVersion)
- GoeScholar The Publication Server of the Georg-August-Universität Göttingen (Georg-August-Universität Göttingen) (submittedVersion, cc-by)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Zurich Open Repository and Archive (University of Zurich)
- Lawrence Berkeley National Laboratory
- Funders
- National Science Foundation (DEAC02-05CH11231)
- U.S. Department of Energy (-AC02-05CH11231, 05CH11231, DE AC02 05CH11231, DE-AC02-)
- Gordon and Betty Moore Foundation
- Joint Genome Institute (AC02-05CH11231, DE–AC02–05CH11231)
- Deutsche Forschungsgemeinschaft (DE-AC02-05CH11231)
- Agence Nationale de la Recherche (DE-AC02-05CH11231)
- Centre National de la Recherche Scientifique (DE-AC02-05CH11231)
- National Institutes of Health (DE-AC02–05CH11231)
- Office of Science (DEAC02–05CH11231, AC02-05CH11231, DE-AC02, 05CH11231)
- Australian Research Council
- National Human Genome Research Institute (DE-AC02-05CH11231, R01HG004164)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Marine Invertebrate Physiology and Ecology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Keywords
- Amphimedon queenslandica, sponge genome, demosponges, origin of animals, transcription factors, signaling pathways, cell cycle regulation, cell adhesion, innate immunity, allorecognition, germ cell specification, multicellularity, cancer, comparative genomics
- MeSH terms
- Animals, Cell Adhesion, Cell Cycle, Genes, Humans, Immunity, Innate, Models, Biological, Neurons, Phosphotransferases, Phylogeny, Porifera, Signal Transduction, Genome, Cell Polarity, Apoptosis, Sequence Analysis, DNA, Evolution, Molecular, Genomics, Cell Proliferation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
