Matters of context guide future research in TGFβ superfamily signaling

A multigenic program mediating breast cancer metastasis to bone

Kang, Y., Siegel, P. M., Shu, W., Drobnjak, M., Käkönen, S.-M., Cordon‐Cardo, C., Guise, T. A., & Massagué, J. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00132-6 · Cited by 2,562 · see citing works

The RNA Binding Protein Quaking Regulates Formation of circRNAs

Conn, S. J., Pillman, K. A., Toubia, J., Conn, V. M., Salmanidis, M., Phillips, C. A., Roslan, S., SCHREIBER, A. W., Gregory, P. A., & Goodall, G. J. (2015) · Cell · doi:10.1016/j.cell.2015.02.014 · Cited by 2,187 · see citing works

Endogenous human microRNAs that suppress breast cancer metastasis

Tavazoie, S. F., Alarcón, C. R., Óskarsson, T., Padua, D. M., Wang, Q., Bos, P. D., Gerald, W. L., & Massagué, J. (2008) · Nature · doi:10.1038/nature06487 · Cited by 1,858 · see citing works

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

Guglielmo, G. M. D., Roy, C. L., Goodfellow, A. F., & Wrana, J. L. (2003) · Nature Cell Biology · doi:10.1038/ncb975 · Cited by 1,152 · see citing works

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

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The Amphimedon queenslandica genome and the evolution of animal complexity

Srivastava, M., Simakov, O., Chapman, J., Fahey, B., Gauthier, M. E. A., Mitros, T., Richards, G. S., Conaco, C., Dacre, M., Hellsten, U., et al. (2010) · Nature · doi:10.1038/nature09201 · Cited by 1,049 · see citing works

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

Katsimpardi, L., Litterman, N. K., Schein, P. A., Miller, C. M., Loffredo, F. S., Wojtkiewicz, G. R., Chen, J. W., Lee, R. T., Wagers, A. J., & Rubin, L. L. (2014) · Science · doi:10.1126/science.1251141 · Cited by 1,037 · see citing works

Latent TGF-β structure and activation

Shi, M., Zhu, J., Wang, R., Chen, X., Mi, L., Walz, T., & Springer, T. A. (2011) · Nature · doi:10.1038/nature10152 · Cited by 1,013 · see citing works

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

Loffredo, F. S., Steinhauser, M. L., Jay, S. M., Gannon, J., Pancoast, J. R., Yalamanchi, P., Sinha, M., Dall’Osso, C., Khong, D., Shadrach, J. L., et al. (2013) · Cell · doi:10.1016/j.cell.2013.04.015 · Cited by 948 · see citing works

The Trichoplax genome and the nature of placozoans

Srivastava, M., Begovic, E., Chapman, J., Putnam, N. H., Hellsten, U., Kawashima, T., Kuo, A., Mitros, T., Salamov, A., Carpenter, M. L., et al. (2008) · Nature · doi:10.1038/nature07191 · Cited by 889 · see citing works

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

Warmflash, A., Sorre, B., Etoc, F., Siggia, E. D., & Brivanlou, A. H. (2014) · Nature Methods · doi:10.1038/nmeth.3016 · Cited by 885 · see citing works

Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

Kretzschmar, M., Doody, J. F., & Massagué, J. (1997) · Nature · doi:10.1038/39348 · Cited by 878 · see citing works

TGF- β signaling in cancer – a double-edged sword

Akhurst, R. J., & Derynck, R. (2001) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02130-4 · Cited by 756 · see citing works

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

Alarcón, C., Zaromytidou, A.-I., Xi, Q., Gao, S., Yu, J., Fujisawa, S., Barlas, A., Miller, A. N., Manova-Todorova, K., Macias, M. J., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.035 · Cited by 719 · see citing works

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

Varelas, X., Samavarchi‐Tehrani, P., Narimatsu, M., Weiss, A., Cockburn, K., Larsen, B. G., Rossant, J., & Wrana, J. L. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.11.012 · Cited by 683 · see citing works

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

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Cytonemes

Ramı́rez-Weber, F.-A., & Kornberg, T. B. (1999) · Cell · doi:10.1016/s0092-8674(00)80771-0 · Cited by 614 · see citing works

Redox-mediated activation of latent transforming growth factor-beta 1

Barcellos‐Hoff, M. H., & Dix, T. A. (1996) · Molecular Endocrinology · doi:10.1210/mend.10.9.8885242 · Cited by 580 · see citing works

Integrating Patterning Signals: Wnt/GSK3 Regulates the Duration of the BMP/Smad1 Signal

Fuentealba, L. C., Eivers, E., Ikeda, A., Hurtado, C., Kuroda, H., Pera, E. M., & Robertis, E. M. D. (2007) · Cell · doi:10.1016/j.cell.2007.09.027 · Cited by 555 · see citing works

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.

Wakefield, L. M., Smith, D. M., Flanders, K. C., & Sporn, M. B. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68547-3 · Cited by 538 · see citing works

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

Taylor, K. R., Mackay, A. G., Truffaux, N., Butterfield, Y. S. N., Morozova, O., Philippe, C., Castel, D., Grasso, C. S., Vinci, M., Carvalho, D. M., et al. (2014) · Nature Genetics · doi:10.1038/ng.2925 · Cited by 522 · see citing works

Latent transforming growth factor-β: Structural features and mechanisms of activation

Munger, J. S., Harpel, J. G., Gleizes, P., Mazzieri, R., Nunes, I., & Rifkin, D. B. (1997) · Kidney International · doi:10.1038/ki.1997.188 · Cited by 513 · see citing works

Cyclin-dependent kinases regulate the antiproliferative function of Smads

Matsuura, I., Denissova, N. G., Wang, G., He, D., Long, J., & Liu, F. (2004) · Nature · doi:10.1038/nature02650 · Cited by 506 · see citing works

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

Steinberg, F., Gallon, M., Winfield, M., Thomas, E. C., Bell, A. J., Heesom, K. J., Tavaré, J. M., & Cullen, P. J. (2013) · Nature Cell Biology · doi:10.1038/ncb2721 · Cited by 505 · see citing works

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling

Bragado, P., Estrada, Y., Parikh, F., Krause, S., Capobianco, C., Farina, H. G., Schewe, D. M., & Aguirre-Ghiso, J. A. (2013) · Nature Cell Biology · doi:10.1038/ncb2861 · Cited by 503 · see citing works

Phase I study of GC1008 (fresolimumab): a human anti‐transforming growth factor‐beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma

Morris, J. C., Tan, A. R., Olencki, T. E., Shapiro, G. I., Dezube, B. J., Reiss, M., Hsu, F. J., Berzofsky, J. A., & Lawrence, D. P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090353 · Cited by 487 · see citing works

EndMT contributes to the onset and progression of cerebral cavernous malformations

Maddaluno, L., Rudini, N., Cuttano, R., Bravi, L., Giampietro, C., Corada, M., Ferrarini, L., Orsenigo, F., Papa, E., Boulday, G., et al. (2013) · Nature · doi:10.1038/nature12207 · Cited by 486 · see citing works

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

Green, J. B. A., New, H. V., & Smith, J. C. (1992) · Cell · doi:10.1016/0092-8674(92)90550-v · Cited by 482 · see citing works

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

Sakamoto, K., & Holman, G. D. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90331.2008 · Cited by 481 · see citing works

Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming

Tiwari, N., Tiwari, V. K., Waldmeier, L., Balwierz, P. J., Arnold, P., Pachkov, M. V., Meyer‐Schaller, N., Schübeler, D., van Nimwegen, E., & Christofori, G. (2013) · Cancer Cell · doi:10.1016/j.ccr.2013.04.020 · Cited by 480 · see citing works

Noncanonical TGFβ Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

Holm, T. M., Habashi, J. P., Doyle, J. J., Bedja, D., Chen, Y., van Erp, C., Lindsay, M. E., Kim, D. S., Schoenhoff, F., Cohn, R. D., et al. (2011) · Science · doi:10.1126/science.1192149 · Cited by 475 · see citing works

TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma

Oshimori, N., Oristian, D., & Fuchs, E. (2015) · Cell · doi:10.1016/j.cell.2015.01.043 · Cited by 471 · see citing works

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

Suragani, R. N. V. S., Cadena, S. M., Cawley, S. M., Sako, D., Mitchell, D., Li, R., Davies, M. V., Alexander, M. J., Devine, M., Loveday, K. S., et al. (2014) · Nature Medicine · doi:10.1038/nm.3512 · Cited by 452 · see citing works

<i>ACVR1</i> ^<i>R206H</i> receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A

Hatsell, S. J., Idone, V., Wolken, D. M. A., Huang, L., Kim, H. J., Wang, L., Wen, X., Nannuru, K. C., Jimenez, J., Xie, L., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aac4358 · Cited by 446 · see citing works

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system.

Sato, Y., Tsuboi, R., Lyons, R., Moses, H., & Rifkin, D. B. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.2.757 · Cited by 444 · see citing works

Transforming growth factor-beta activation in irradiated murine mammary gland.

Barcellos‐Hoff, M. H., Derynck, R., Tsang, M., & Weatherbee, J. A. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117045 · Cited by 428 · see citing works

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural inductionPreprint

Pera, E. M., Ikeda, A., Eivers, E., & Robertis, E. M. D. (2003) · Genes & Development · doi:10.1101/gad.1153603 · Cited by 421 · see citing works

Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

Horan, G. S., Wood, S., Ona, V., Li, D. J., Lukashev, M. E., Weinreb, P. H., Simon, K. J., Hahm, K., Allaire, N. E., Rinaldi, N. J., et al. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200706-805oc · Cited by 420 · see citing works

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

Sapkota, G. P., Alarcón, C. R., Spagnoli, F. M., Brivanlou, A. H., & Massagué, J. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.01.006 · Cited by 419 · see citing works

Beyond TGFβ: roles of other TGFβ superfamily members in cancer

Wakefield, L. M., & Hill, C. S. (2013) · Nature reviews. Cancer · doi:10.1038/nrc3500 · Cited by 373 · see citing works

NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes

Sosa, M. S., Parikh, F., Gaspar‐Maia, A., Estrada, Y. D., Bosch, A., Bragado, P., Ekpin, E., George, A. D., Zheng, Y., Lam, H., et al. (2015) · Nature Communications · doi:10.1038/ncomms7170 · Cited by 357 · see citing works

Smad2 Protects against TGF-β/Smad3-Mediated Renal Fibrosis

Meng, X., Huang, X. R., Chung, A. C. K., Qin, W., Shao, X., Igarashi, P., Ju, W., Böttinger, E. P., & Lan, H. Y. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009121244 · Cited by 338 · see citing works

BMP gradients: A paradigm for morphogen-mediated developmental patterning

Bier, E., & Robertis, E. M. D. (2015) · Science · doi:10.1126/science.aaa5838 · Cited by 312 · see citing works

The α _v β ₁ integrin plays a critical in vivo role in tissue fibrosis

Reed, N. I., Jo, H., Chen, C., Tsujino, K., Arnold, T. D., DeGrado, W. F., & Sheppard, D. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa5094 · Cited by 311 · see citing works

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.

Francois, V, Solloway, M., O'Neill, J. W., Emery, J., & Bier, E. (1994) · Genes &amp; Development · doi:10.1101/gad.8.21.2602 · Cited by 308 · see citing works

Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells

Beyer, T. A., Weiss, A., Khomchuk, Y., Huang, K., Ogunjimi, A. A., Varelas, X., & Wrana, J. L. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.11.021 · Cited by 293 · see citing works

Membrane protein GARP is a receptor for latent TGF‐β on the surface of activated human Treg

Stockis, J., Colau, D., Coulie, P. G., & Lucas, S. (2009) · European Journal of Immunology · doi:10.1002/eji.200939684 · Cited by 252 · see citing works

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

Bischoff, M., Gradilla, A., Seijo-Barandiarán, I., Andrés, G., Rodríguez‐Navas, C., González‐Méndez, L., & Guerrero, I. (2013) · Nature Cell Biology · doi:10.1038/ncb2856 · Cited by 251 · see citing works

The type III TGF-β receptor suppresses breast cancer progression

Dong, M., How, T., Kirkbride, K. C., Gordon, K. J., Lee, J. D., Hempel, N., Kelly, P., Moeller, B. J., Marks, J. R., & Blobe, G. C. (2006) · Journal of Clinical Investigation · doi:10.1172/jci29293 · Cited by 246 · see citing works

An Anti–Transforming Growth Factor β Antibody Suppresses Metastasis via Cooperative Effects on Multiple Cell Compartments

Nam, J., Terabe, M., Mamura, M., Kang, M., Chae, H., Stuelten, C. H., Kohn, E. A., Tang, B., Sabzevari, H., Anver, M. R., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-0215 · Cited by 233 · see citing works

Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion

Gradilla, A., González, E., Seijo-Barandiarán, I., Andrés, G., Bischoff, M., González‐Méndez, L., Sánchez, V., Callejo, A., Ibáñez, C., Guerra, M., et al. (2014) · Nature Communications · doi:10.1038/ncomms6649 · Cited by 225 · see citing works

Cytoneme-Mediated Contact-Dependent Transport of the Drosophila Decapentaplegic Signaling Protein

Roy, S., Huang, H., Liu, S., & Kornberg, T. B. (2014) · Science · doi:10.1126/science.1244624 · Cited by 223 · see citing works

Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression

Hoot, K. E., Lighthall, J. G., Han, G., Lu, S., Li, A., Ju, W., Kulesz-Martin, M. F., Böttinger, E. P., & Wang, X.-J. (2008) · Journal of Clinical Investigation · doi:10.1172/jci33713 · Cited by 209 · see citing works

αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

Hahm, K., Lukashev, M. E., Luo, Y., Yang, W. J., Dolinski, B. M., Weinreb, P. H., Simon, K. J., Chun Wang, L., Leone, D. R., Lobb, R. R., et al. (2007) · The American Journal of Pathology · doi:10.2353/ajpath.2007.060158 · Cited by 190 · see citing works

Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway

Penheiter, S. G., Mitchell, H. D., Garamszegi, N., Edens, M., Doré, J. J. E., & Leof, E. B. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.13.4750-4759.2002 · Cited by 188 · see citing works

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom

Huminiecki, Ł., Goldovsky, L., Freilich, S., Moustakas, A., Ouzounis, C. A., & Heldin, C. (2009) · BMC Evolutionary Biology · doi:10.1186/1471-2148-9-28 · Cited by 183 · see citing works

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer

Mu, Y., Sundar, R., Thakur, N., Ekman, M., Gudey, S. K., Yakymovych, M., Hermansson, A., Dimitriou, H., Bengoechea-Alonso, M. T., Ericsson, J., et al. (2011) · Nature Communications · doi:10.1038/ncomms1332 · Cited by 182 · see citing works

Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities

Porter, D. C., Farmaki, E., Altilia, S., Schools, G. P., West, D. K., Chen, M., Chang, B.-D., Puzyrev, A. T., Lim, C., Rokow-Kittell, R., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206906109 · Cited by 175 · see citing works

Essential Role of TGF-β Signaling in Glucose-Induced Cell Hypertrophy

Wu, L., & Derynck, R. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.05.010 · Cited by 167 · see citing works

Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B

Olsen, O. E., Wader, K. F., Hella, H., Mylin, A. K., Turesson, I., Nesthus, I., Waage, A., Sundan, A., & Holien, T. (2015) · Cell Communication and Signaling · doi:10.1186/s12964-015-0104-z · Cited by 166 · see citing works

Klf4 Is a Transcriptional Regulator of Genes Critical for EMT, Including Jnk1 (Mapk8)

Tiwari, N., Meyer‐Schaller, N., Arnold, P., Antoniadis, H., Pachkov, M. V., van Nimwegen, E., & Christofori, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057329 · Cited by 165 · see citing works

Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo

Cuende, J., Liénart, S., Dedobbeleer, O., van der Woning, B., De Boeck, G., Stockis, J., Huygens, C., Colau, D., Somja, J., Delvenne, P., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa1983 · Cited by 155 · see citing works

Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008)

Lacouture, M. E., Morris, J. C., Lawrence, D. P., Tan, A. R., Olencki, T. E., Shapiro, G. I., Dezube, B. J., Berzofsky, J. A., Hsu, F. J., & Guitart, J. (2015) · Cancer Immunology, Immunotherapy · doi:10.1007/s00262-015-1653-0 · Cited by 145 · see citing works

Chordin Is Required for the Spemann Organizer Transplantation Phenomenon in Xenopus Embryos

Oelgeschläger, M., Kuroda, H., Reversade, B., & Robertis, E. M. D. (2003) · Developmental Cell · doi:10.1016/s1534-5807(02)00404-5 · Cited by 145 · see citing works

Structural determinants of integrin β-subunit specificity for latent TGF-β

Dong, X., Hudson, N. E., Lu, C., & Springer, T. A. (2014) · Nature Structural &amp; Molecular Biology · doi:10.1038/nsmb.2905 · Cited by 141 · see citing works

Genome‐wide identification of miR‐200 targets reveals a regulatory network controlling cell invasion

Bracken, C. P., Li, X., Wright, J. A., Lawrence, D., Pillman, K. A., Salmanidis, M., Anderson, M. A., Dredge, B. K., Gregory, P. A., Tsykin, A., et al. (2014) · The EMBO Journal · doi:10.15252/embj.201488641 · Cited by 134 · see citing works

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursorPreprint

Cui, Y., Hackenmiller, R., Berg, L. K., Jean, F., Nakayama, T., Thomas, G., & Christian, J. L. (2001) · Genes & Development · doi:10.1101/gad.940001 · Cited by 134 · see citing works

Tead2 expression levels control Yap/Taz subcellular distribution, zyxin expression, and epithelial-mesenchymal transition

Diepenbruck, M., Waldmeier, L., Ivánek, R., Berninger, P., Arnold, P., van Nimwegen, E., & Christofori, G. (2014) · Journal of Cell Science · doi:10.1242/jcs.139865 · Cited by 132 · see citing works

Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium

Huang, H., & Kornberg, T. B. (2015) · eLife · doi:10.7554/elife.06114 · Cited by 131 · see citing works

Sorting Nexin 6, a Novel SNX, Interacts with the Transforming Growth Factor-β Family of Receptor Serine-Threonine Kinases

Parks, W. T., Frank, D. B., Huff, C., Haft, C. R., Martin, J. M., Meng, X., de Caestecker, M. P., McNally, J. G., Reddi, A. R., Taylor, S. I., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100606200 · Cited by 131 · see citing works

Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment

Hanks, B. A., Holtzhausen, A., Evans, K. S., Jamieson, R., Gimpel, P., Campbell, O. M., Hector-Greene, M., Sun, L., Tewari, A. K., George, A., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci65745 · Cited by 120 · see citing works

Autocrine Bone Morphogenetic Protein-9 Signals through Activin Receptor-like Kinase-2/Smad1/Smad4 to Promote Ovarian Cancer Cell Proliferation

Herrera, B. M., van Dinther, M., ten Dijke, P., & Inman, G. J. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-2912 · Cited by 120 · see citing works

Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts

Olson, K. A., Beatty, A. L., Heidecker, B., Regan, M. C., Brody, E. N., Foreman, T. M., Kato, S., Mehler, R. E., Singer, B. S., Hveem, K., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv385 · Cited by 117 · see citing works

Latent beta-transforming growth factor in nontransformed and Kirsten sarcoma virus-transformed normal rat kidney cells, clone 49F.

Pircher, R., Lawrence, D. A., & Jullien, P. (1984) · PubMed · Cited by 112 · see citing works

Structure of bone morphogenetic protein 9 procomplex

Mi, L.-Z., Brown, C. T., Gao, Y., Tian, Y., Le, V. Q., Walz, T., & Springer, T. A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1501303112 · Cited by 112 · see citing works

Inhibition of BMP signaling suppresses metastasis in mammary cancer

Owens, P., Pickup, M. W., Novitskiy, S. V., Giltnane, J. M., Gorska, A. E., Hopkins, C. R., Hong, C. C., & Moses, H. L. (2014) · Oncogene · doi:10.1038/onc.2014.189 · Cited by 106 · see citing works

CRIM1 Regulates the Rate of Processing and Delivery of Bone Morphogenetic Proteins to the Cell Surface

Wilkinson, L. J., Kolle, G., Wen, D., Piper, M., Scott, J. C., & Little, M. H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301247200 · Cited by 106 · see citing works

Cleavages within the Prodomain Direct Intracellular Trafficking and Degradation of Mature Bone Morphogenetic Protein-4

Degnin, C., Jean, F., Thomas, G., et al. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-08-0673 · Cited by 103 · see citing works

Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β8

Edwards, J. P., Thornton, A. M., & Shevach, E. M. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1401102 · Cited by 99 · see citing works

Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomes

He, K., Yan, X., Li, N., Dang, S., Xu, L., Zhao, B. T., Li, Z., Lv, Z., Fang, X., Zhang, Y., et al. (2015) · Cell Research · doi:10.1038/cr.2015.60 · Cited by 98 · see citing works

Structure–Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants

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