The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons
Abstract
Sensory information may be represented in the brain by stereotyped mapping of axonal inputs or by patterning that varies between individuals. In olfaction, a stereotyped map is evident in the first sensory processing centre, the olfactory bulb (OB), where different odours elicit activity in unique combinatorial patterns of spatially invariant glomeruli. Activation of each glomerulus is relayed to higher cortical processing centres by a set of ∼20-50 'homotypic' mitral and tufted (MT) neurons. In the cortex, target neurons integrate information from multiple glomeruli to detect distinct features of chemically diverse odours. How this is accomplished remains unclear, perhaps because the cortical mapping of glomerular information by individual MT neurons has not been described. Here we use new viral tracing and three-dimensional brain reconstruction methods to compare the cortical projections of defined sets of MT neurons. We show that the gross-scale organization of the OB is preserved in the patterns of axonal projections to one processing centre yet reordered in another, suggesting that distinct coding strategies may operate in different targets. However, at the level of individual neurons neither glomerular order nor stereotypy is preserved in either region. Rather, homotypic MT neurons from the same glomerulus innervate broad regions that differ between individuals. Strikingly, even in the same animal, MT neurons exhibit extensive diversity in wiring; axons of homotypic MT…
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“Likewise, the NN is meshed across the entire nervous system, with even single neurons known to link distant regions (59).”
From Behavior-related gene regulatory networks: A new level of organization in the brain (2020) · cites this paper as [59]
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A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
Buck, L., & Axel, R. (1991) · Cell · doi:10.1016/0092-8674(91)90418-x · Cited by 4,987
Shaner, N. C., Campbell, R. E., Steinbach, P. A., Giepmans, B. N. G., Palmer, A. E., & Tsien, R. Y. (2004) · Nature Biotechnology · doi:10.1038/nbt1037 · Cited by 4,619
Visualizing an Olfactory Sensory Map
Mombaerts, P., Wang, F., Dulac, C. G., Chao, S. K., Nemes, A., Mendelsohn, M. M., Edmondson, J., & Axel, R. (1996) · Cell · doi:10.1016/s0092-8674(00)81387-2 · Cited by 1,992
Topographic organization of sensory projections to the olfactory bulb
Vassar, R., Chao, S. K., Sitcheran, R., Nun˜ez, J. M., Vosshall, L. B., & Axel, R. (1994) · Cell · doi:10.1016/0092-8674(94)90029-9 · Cited by 1,295
Ressler, K. J., Sullivan, S. L., & Buck, L. B. (1994) · Cell · doi:10.1016/0092-8674(94)90015-9 · Cited by 1,202
Chaffey, N. (2001) · Trends in Plant Science · doi:10.1016/s1360-1385(01)01902-1 · Cited by 1,043
The Functional Organization of the Barrel Cortex
Petersen, C. C. H. (2007) · Neuron · doi:10.1016/j.neuron.2007.09.017 · Cited by 732
Optical Imaging of Odorant Representations in the Mammalian Olfactory Bulb
Rubin, B. D., & Katz, L. C. (1999) · Neuron · doi:10.1016/s0896-6273(00)80803-x · Cited by 672
Bright monomeric red fluorescent protein with an extended fluorescence lifetime
Merzlyak, E. M., Goedhart, J., Shcherbo, D. S., Bulina, M. E., Shcheglov, A. S., Fradkov, A. F., Gaintzeva, A., Lukyanov, K. A., Lukyanov, S., Gadella, T. W. J., et al. (2007) · Nature Methods · doi:10.1038/nmeth1062 · Cited by 635
Representations of Odor in the Piriform Cortex
Stettler, D. D., & Axel, R. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.005 · Cited by 577
Cited by
Winnubst, J., Bas, E., Ferreira, T. A., Wu, Z., Economo, M. N., Edson, P., Arthur, B. J., Bruns, C., Rokicki, K., Schauder, D., et al. (2019) · Cell · doi:10.1016/j.cell.2019.07.042 · Cited by 538
At the interface of sensory and motor dysfunctions and Alzheimer’s disease.
Albers, M. W., Gilmore, G. C., Kaye, J., Murphy, C., Wingfield, A., Bennett, D. A., Boxer, A. L., Buchman, A. S., Cruickshanks, K. J., Devanand, D. P., et al. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.04.514 · Cited by 589
Distinct representations of olfactory information in different cortical centres
Sosulski, D. L., Bloom, M. L., Cutforth, T., Axel, R., & Datta, S. R. (2011) · Nature · doi:10.1038/nature09868 · Cited by 479
Self-citationCortical processing of odor objects.
Wilson, D. A., & Sullivan, R. M. (2011) · Neuron · doi:10.1016/j.neuron.2011.10.027 · Cited by 468
High-throughput mapping of single-neuron projections by sequencing of barcoded RNA
Kebschull, J. M., Garcia da Silva, P., Reid, A. P., Peikon, I. D., Albeanu, D. F., & Zador, A. M. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.036 · Cited by 376
Metadata
- Authors
- Ghosh, S., Larson, S. D., Hefzi, H., Marnoy, Z., Cutforth, T., Dokka, K., & Baldwin, K. K.
- Venue
- Nature
- Published
- 2011-03-30
- Volume
- 472
- Issue
- 7342
- Pages
- 217-220
- ISSN
- 0028-0836
- 1476-4687
- Cited by
- 276
- References
- 36
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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