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Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

Lafaille, Fabien G., Pessach, Itai M., Zhang, Shen-Ying, Ciancanelli, Michael J., Herman, Melina, Abhyankar, Avinash, Ying, Shui-Wang, Keros, Sotirios, Goldstein, Peter A., Mostoslavsky, Gustavo, Ordovas-Montanes, Jose, Jouanguy, Emmanuelle, Plancoulaine, Sabine, Tu, Edmund, Elkabetz, Yechiel, Al-Muhsen, Saleh, Tardieu, Marc, Schlaeger, Thorsten M., Daley, George Q., Abel, Laurent, Casanova, Jean-Laurent, Studer, Lorenz, Notarangelo, Luigi D.·2012·Nature
DOI 10.1038/nature11583PMC PMC3527075
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Research works printed but not linked: 39

  1. Casrouge, A. et al. Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 314, 308–312 (2006) · DOI · Paper page
  2. Zhang, S. Y. et al. TLR3 deficiency in patients with herpes simplex encephalitis. Science 317, 1522–1527 (2007) · DOI · Paper page
  3. Guo, Y. et al. Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity. J. Exp. Med. 208, 2083–2098 (2011) · DOI
  4. Whitley, R. J. Herpes simplex encephalitis: adolescents and adults. Antiviral Res. 71, 141–148 (2006) · DOI
  5. Abel, L. et al. Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood. J. Pediatr. 157, 623–629 (2010) · DOI
  6. Kim, Y. M., Brinkmann, M. M., Paquet, M. E. & Ploegh, H. L. UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 452, 234–238 (2008) · DOI · Paper page
  7. Pérez de Diego, R. et al. Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis. Immunity 33, 400–411 (2010) · DOI
  8. Sancho-Shimizu, V. et al. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J. Clin. Invest. 121, 4889–4902 (2011) · DOI
  9. Herman, M. et al. Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood. J. Exp. Med. 209, 1567–1582 (2012) · DOI
  10. Jacquemont, B. & Roizman, B. RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them. J. Virol. 15, 707–713 (1975) · DOI
  11. Weber, F., Wagner, V., Rasmussen, S. B., Hartmann, R. & Paludan, S. R. Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses. J. Virol. 80, 5059–5064 (2006) · DOI
  12. Bsibsi, M., Ravid, R., Gveric, D. & van Noort, J. M. Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neurol. 61, 1013–1021 (2002) · DOI
  13. Préhaud, C., Megret, F., Lafage, M. & Lafon, M. Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon. J. Virol. 79, 12893–12904 (2005) · DOI
  14. Zhou, L. et al. Activation of Toll-like receptor-3 induces interferon-lambda expression in human neuronal cells. Neuroscience 159, 629–637 (2009) · DOI
  15. Mitchell, B. M., Bloom, D. C., Cohrs, R. J., Gilden, D. H. & Kennedy, P. G. Herpes simplex virus-1 and varicella-zoster virus latency in ganglia. J. Neurovirol. 9, 194–204 (2003) · DOI
  16. Lokensgard, J. R. et al. Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus. J. Neurovirol. 7, 208–219 (2001) · DOI
  17. Bello-Morales, R., Fedetz, M., Alcina, A., Tabares, E. & Lopez-Guerrero, J. A. High susceptibility of a human oligodendroglial cell line to herpes simplex type 1 infection. J. Neurovirol. 11, 190–198 (2005) · DOI
  18. Marques, C. P., Hu, S., Sheng, W. & Lokensgard, J. R. Microglial cells initiate vigorous yet non-protective immune responses during HSV-1 brain infection. Virus Res. 121, 1–10 (2006) · DOI
  19. Pessach, I. M. et al. Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies. J. Allergy Clin. Immunol. 127, 1400–1407 (2011) · DOI
  20. Kriks, S. et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480, 547–551 (2011) 10.1038/nature10648 · DOI
  21. Tabar, V. et al. Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nature Biotechnol. 23, 601–606 (2005) · DOI
  22. Jackson, A. C., Rossiter, J. P. & Lafon, M. Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases. J. Neurovirol. 12, 229–234 (2006) · DOI
  23. Farina, C. et al. Preferential expression and function of Toll-like receptor 3 in human astrocytes. J. Neuroimmunol. 159, 12–19 (2005) · DOI
  24. Taupin, P. & Gage, F. H. Adult neurogenesis and neural stem cells of the central nervous system in mammals. J. Neurosci. Res. 69, 745–749 (2002) · DOI
  25. Desai, P. & Person, S. Incorporation of the green fluorescent protein into the herpes simplex virus type 1 capsid. J. Virol. 72, 7563–7568 (1998) · DOI
  26. Reinert, L. S. et al. TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice. J. Clin. Invest. 122, 1368–1376 (2012) · DOI
  27. Bieniasz, P. D. Intrinsic immunity: a front-line defense against viral attack. Nature Immunol. 5, 1109–1115 (2004) · DOI
  28. Park, I. H. et al. Disease-specific induced pluripotent stem cells. Cell 134, 877–886 (2008) · DOI · Paper page
  29. Barberi, T. et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nature Biotechnol. 21, 1200–1207 (2003) · DOI
  30. Perrier, A. L. et al. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc. Natl Acad. Sci. USA 101, 12543–12548 (2004) · DOI
  31. Somers, A. et al. Generation of transgene-free lung-disease specific human iPS cells using a single excisable lentiviral stem cell cassette. Stem Cells 28, 1728–1740 (2010) · DOI · Paper page
  32. Mostoslavsky, G., Fabian, A. J., Rooney, S., Alt, F. W. & Mulligan, R. C. Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Proc. Natl Acad. Sci. USA 103, 16406–16411 (2006) · DOI
  33. Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754–1760 (2009) · DOI · Paper page
  34. McKenna, A. et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 20, 1297–1303 (2010) · DOI · Paper page
  35. Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078–2079 (2009) · DOI · Paper page
  36. Ying, S. W. & Goldstein, P. A. Propofol-block of SK channels in reticular thalamic neurons enhances GABAergic inhibition in relay neurons. J. Neurophysiol. 93, 1935–1948 (2005) · DOI
  37. Ying, S. W. et al. Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons. J. Neurosci. 27, 8719–8732 (2007) · DOI
  38. Park, I. H. et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451, 141–146 (2008) · DOI · Paper page
  39. Yang, K. et al. Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses. Immunity 23, 465–478 (2005) · DOI

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Metadata

Authors
Lafaille, F. G., Pessach, I. M., Zhang, S.-Y., Ciancanelli, M. J., Herman, M., Abhyankar, A., Ying, S.-W., Keros, S., Goldstein, P. A., Mostoslavsky, G., Ordovas-Montanes, J., Jouanguy, E., Plancoulaine, S., Tu, E., Elkabetz, Y., Al-Muhsen, S., Tardieu, M., Schlaeger, T. M., Daley, G. Q., Abel, L., Casanova, J.-L., Studer, L., & Notarangelo, L. D.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2012-10-28
Volume
491
Issue
7426
Pages
769-773
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/nature11583
PMC
PMC3527075
Cited by
318
References
3
Language
en
Licence
www.springer.com/tdm (tdm)

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