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The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX

Ko, Myunggon, An, Jungeun, Bandukwala, Hozefa S., Chavez, Lukas, Äijö, Tarmo, Pastor, William A., Segal, Matthew F., Li, Huiming, Koh, Kian Peng, Lähdesmäki, Harri, Hogan, Patrick G., Aravind, L., Rao, Anjana·2013·Nature
DOI 10.1038/nature12052PMC PMC3643997
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Research works printed but not linked: 34

  1. Tahiliani, M. et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930–935 (2009) · DOI · Paper page
  2. Iyer, L. M., Tahiliani, M., Rao, A. & Aravind, L. Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle 8, 1698–1710 (2009) · DOI
  3. Ko, M. et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468, 839–843 (2010) · DOI · Paper page
  4. He, Y. F. et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333, 1303–1307 (2011) · DOI
  5. Maiti, A. & Drohat, A. C. Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G.T mispairs. DNA Repair 10, 545–553 (2011) · DOI
  6. Hino, S. et al. Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein. Mol. Cell. Biol. 21, 330–342 (2001) · DOI
  7. Kojima, T. et al. Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling. Oncogene 28, 297–305 (2009) · DOI
  8. Nguyen, A. V., Albers, C. G. & Holcombe, R. F. Differentiation of tubular and villous adenomas based on Wnt pathway-related gene expression profiles. Int. J. Mol. Med. 26, 121–125 (2010)
  9. Iyer, L. M., Abhiman, S. & Aravind, L. Natural history of eukaryotic DNA methylation systems. Prog. Mol. Biol. Transl. Sci. 101, 25–104 (2011) · DOI
  10. Cierpicki, T. et al. Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia. Nature Struct. Mol. Biol. 17, 62–68 (2010) · DOI
  11. Allen, M. D. et al. Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase. EMBO J. 25, 4503–4512 (2006) · DOI
  12. Song, J., Rechkoblit, O., Bestor, T. H. & Patel, D. J. Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science 331, 1036–1040 (2011) · DOI
  13. Blackledge, N. P. et al. CpG islands recruit a histone H3 lysine 36 demethylase. Mol. Cell 38, 179–190 (2010) · DOI
  14. Xu, Y. et al. Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell 151, 1200–1213 (2012) · DOI · Paper page
  15. Koh, K. P. et al. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 8, 200–213 (2011) · DOI · Paper page
  16. Ko, M. et al. Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc. Natl Acad. Sci. USA 108, 14566–14571 (2011) · DOI · Paper page
  17. Knappskog, S. et al. RINF (CXXC5) is overexpressed in solid tumors and is an unfavorable prognostic factor in breast cancer. Ann. Oncol. 22, 2208–2215 (2011) · DOI
  18. Kim, M. S. et al. A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway. J. Biol. Chem. 285, 14585–14593 (2010) · DOI
  19. Pendino, F. et al. Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis. Blood 113, 3172–3181 (2009) · DOI
  20. Fujita, J. et al. Caspase activity mediates the differentiation of embryonic stem cells. Cell Stem Cell 2, 595–601 (2008) · DOI
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  22. Nestor, C. E. et al. Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes. Genome Res. 22, 467–477 (2012) · DOI
  23. Globisch, D. et al. Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS ONE 5, e15367 (2010) · DOI
  24. Haffner, M. C. et al. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget 2, 627–637 (2011) · DOI
  25. Sokol, S. Y. Maintaining embryonic stem cell pluripotency with Wnt signaling. Development 138, 4341–4350 (2011) · DOI
  26. Yang, H. et al. Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene 32, 663–669 (2013) · DOI
  27. Zhang, Y. et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9, R137 (2008) · DOI · Paper page
  28. Heinz, S. et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576–589 (2010) · DOI · Paper page
  29. Gardiner-Garden, M. et al. CpG islands in vertebrate genomes. J. Mol. Biol. 196, 261–282 (1987) · DOI
  30. Dreszer, T. R. et al. The UCSC Genome Browser database: extensions and updates 2011. Nucleic Acids Res. 40, D918–D923 (2012) · DOI
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  32. Arnold, K. et al. The protein model portal. J. Struct. Funct. Genomics 10, 1–8 (2009) · DOI
  33. Pieper, U. et al. MODBASE, a database of annotated comparative protein structure models and associated resources. Nucleic Acids Res. 32, D217–D222 (2004) · DOI
  34. Huang, C. C., Couch, G. S., Pettersen, E. F. & Ferrin, T. E. Chimera: an Extensible Molecular Modeling Application Constructed Using Standard Components Vol. 1 724 (Pacific Symposium on Biocomputing, 1996)

Cited by

Metadata

Authors
Ko, M., An, J., Bandukwala, H. S., Chavez, L., Äijö, T., Pastor, W. A., Segal, M. F., Li, H., Koh, K. P., Lähdesmäki, H., Hogan, P. G., Aravind, L., & Rao, A.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2013-04-07
Volume
497
Issue
7447
Pages
122-126
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/nature12052
PMC
PMC3643997
Cited by
373
References
6
Language
en
Licence
www.springer.com/tdm (tdm)

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