The microbiome and innate immunity

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444

Diversity of the Human Intestinal Microbial Flora

Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., DuGar, B., Feldstein, A. E., Britt, E. B., Fu, X., Chung, Y.-M., et al. (2011) · Nature · doi:10.1038/nature09922 · Cited by 5,597

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H., et al. (2001) · Nature · doi:10.1038/35079114 · Cited by 5,030

Richness of human gut microbiome correlates with metabolic markers

Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

Koeth, R. A., Wang, Z., Levison, B. S., Buffa, J. A., Org, E., Sheehy, B. T., Britt, E. B., Fu, X., Wu, Y., Li, L., et al. (2013) · Nature Medicine · doi:10.1038/nm.3145 · Cited by 4,386

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy

Sivan, A., Corrales, L., Hubert, N., Williams, J. B., Aquino-Michaels, K., Earley, Z. M., Benyamin, F. W., Man Lei, Y., Jabri, B., Alegre, M.-L., et al. (2015) · Science · doi:10.1126/science.aac4255 · Cited by 3,888

Type 2 diabetes as an inflammatory disease

Donath, M. Y., & Shoelson, S. E. (2011) · Nature Reviews Immunology · doi:10.1038/nri2925 · Cited by 3,737

AACR White Paper: Shaping the Future of Cancer Prevention – A Roadmap for Advancing Science and Public Health

Lippman, S. M., Abate-Shen, C. T., Maresso, K. C., Colditz, G. A., Dannenberg, A. J., Davidson, N. E., Disis, M. L., DuBois, R. N., Szabo, E. M., Giuliano, A. R., et al. (2018) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-18-0421 · Cited by 48

The impact of in utero HIV exposure on gut microbiota, inflammation, and microbial translocation

Machiavelli, A., Duarte, R. T. D., Pires, M. M. D. S., Zárate-Bladés, C. R., & Pinto, A. R. (2019) · Gut Microbes · doi:10.1080/19490976.2018.1560768 · Cited by 47

Constitutive Immune Activity Promotes Tumorigenesis in Drosophila Intestinal Progenitor Cells

Petkau, K., Ferguson, M., Guntermann, S., & Foley, E. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.07.078 · Cited by 47

Dual Role of Bacteria in Carcinoma: Stimulation and Inhibition

Al-Hilu, S. A., & Al-Shujairi, W. H. (2020) · International Journal of Microbiology · doi:10.1155/2020/4639761 · Cited by 48

Yeast β-Glucan Altered Intestinal Microbiome and Metabolome in Older Hens

Zhen, W., Liu, Y., Shao, Y., Ma, Y., Wu, Y., Guo, F., Abbas, W., Guo, Y., & Wang, Z. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.766878 · Cited by 46

Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease

Kayongo, A., Robertson, N. M., Siddharthan, T., Ntayi, M. L., Ndawula, J. C., Sande, O. J., Bagaya, B. S., Kirenga, B., Mayanja‐Kizza, H., Joloba, M. L., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1085551 · Cited by 50

Gut microbiota and tumor-associated macrophages: potential in tumor diagnosis and treatment

Zhou, D., & Li, Y. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2276314 · Cited by 48

Aryl hydrocarbon receptor/IL-22/Stat3 signaling pathway is involved in the modulation of intestinal mucosa antimicrobial molecules by commensal microbiota in mice

Wang, J., Wang, P., Tian, H., Tian, F., Zhang, Y., Zhang, L., Gao, X., & Wang, X. (2018) · Innate Immunity · doi:10.1177/1753425918785016 · Cited by 47

Isolation and characterization of the Bacillus cereus BC7 strain, which is capable of zearalenone removal and intestinal flora modulation in mice

Wang, Y., Zhang, J., Wang, Y., Wang, K., Hong Kui, W. E. I., & Shen, L. (2018) · Toxicon · doi:10.1016/j.toxicon.2018.09.005 · Cited by 46

The Microbiota-Gut Axis in Premature Infants: Physio-Pathological Implications

Bresesti, I., Salvatore, S., Valetti, G., Baj, A., Giaroni, C., & Agosti, M. A. (2022) · Cells · doi:10.3390/cells11030379 · Cited by 51

Edible plant-derived nanotherapeutics and nanocarriers: recent progress and future directions

Chen, N., Sun, J., Zhu, Z., Cribbs, A. P., & Xiao, B. (2022) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2022.2053673 · Cited by 46

Effects of gut microbiota on host adaptive immunity under immune homeostasis and tumor pathology state

Li, Y., Ye, Z., Zhu, J., Fang, S., Meng, L., & Zhou, C. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.844335 · Cited by 45

The Formation of Glycan-Specific Natural Antibodies Repertoire in GalT-KO Mice Is Determined by Gut Microbiota

Bello‐Gil, D., Audebert, C., Olivera‐Ardid, S., Pérez-Cruz, M., Even, G., Khasbiullina, N. R., Gantois, N., Shilova, N. V., Merlin, S., Costa, C., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00342 · Cited by 45

2’-Fucosyllactose Ameliorates Chemotherapy-Induced Intestinal Mucositis by Protecting Intestinal Epithelial Cells Against Apoptosis

Zhao, G., Williams, J. N., Washington, M. K., Yang, Y., Long, J., Townsend, S. D., & Yan, F. (2021) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2021.09.015 · Cited by 46

Bifunctional Fusion Membrane‐Based Hydrogel Enhances Antitumor Potency of Autologous Cancer Vaccines by Activating Dendritic Cells

Ke, Y., Zhu, J., Chu, Y., Cen, L., Fu, Y. S., Fan, X., Shao, J., Li, R., Yu, L., Liu, B., et al. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202201306 · Cited by 45

Profiling the airway in the macaque model of tuberculosis reveals variable microbial dysbiosis and alteration of community structure

Cadena, A. M., Ma, Y., Ding, T., Bryant, M., Maiello, P. A., Geber, A. B., Lin, P. L., Flynn, J. L., & Ghedin, E. (2018) · Microbiome · doi:10.1186/s40168-018-0560-y · Cited by 44

Interaction between microbiota and immunity and its implication in colorectal cancer

Xing, C., Du, Y., Duan, T., Nim, K., Chu, J., Wang, H. Y., & Wang, R. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.963819 · Cited by 47

Modulating effects of Astragalus polysaccharide on immune disorders via gut microbiota and the TLR4/NF-κB pathway in rats with syndrome of dampness stagnancy due to spleen deficiency

Zhao, W., Duan, C.-C., Liu, Y., Lu, G., Lyu, Q., Liu, X., Zheng, J., Zhao, X., Wang, S., & Zhao, H. (2023) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b2200491 · Cited by 44

Large Yellow Tea Polysaccharide Alleviates HFD-Induced Intestinal Homeostasis Dysbiosis via Modulating Gut Barrier Integrity, Immune Responses, and the Gut Microbiome

Ma, Y., Xie, H., Xu, N., Li, M., Wang, L., Ge, H., Xie, Z., Li, D., & Wang, H. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c00616 · Cited by 44

The gut-lung axis: effects and mechanisms of gut microbiota on pulmonary diseases

Liu, J., Hong, W., Sun, Z., Zhang, S., Xue, C., & Dong, N. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1693964 · Cited by 46

Group III phospholipase A2 promotes colitis and colorectal cancer

Murase, R., Taketomi, Y., Miki, Y., Nishito, Y., Saito, M., Fukami, K., Yamamoto, K., & Murakami, M. (2017) · Scientific Reports · doi:10.1038/s41598-017-12434-z · Cited by 44

Functional Classification of the Gut Microbiota: The Key to Cracking the Microbiota Composition Code

Rosen, C. E., & Palm, N. W. (2017) · BioEssays · doi:10.1002/bies.201700032 · Cited by 45

Opportunities and Challenges of the Human Microbiome in Ovarian Cancer

Cheng, H., Wang, Z., Cui, L., Wen, Y. L., Chen, X., Gong, F., & Yi, H. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00163 · Cited by 45

Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19

Baghbani, T., Nikzad, H., Azadbakht, J., Izadpanah, F., & Kashani, H. H. (2020) · Microbial Cell Factories · doi:10.1186/s12934-020-01483-1 · Cited by 45

Gastric Adenocarcinomas and Signet-Ring Cell Carcinoma: Unraveling Gastric Cancer Complexity through Microbiome Analysis—Deepening Heterogeneity for a Personalized Therapy

Ravegnini, G., Fosso, B., Saverio, V. D., Sammarini, G., Zanotti, F., Rossi, G., Ricci, M., D’Amico, F., Valori, G., Ioli, A., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249735 · Cited by 45

Parents with periodontitis impact the subgingival colonization of their offspring

Monteiro, M. F., Altabtbaei, K., Kumar, P., Casati, M. Z., Silvério, K. G., Sallum, E. A., Nociti, F. H., & Casarin, R. C. V. (2021) · Scientific Reports · doi:10.1038/s41598-020-80372-4 · Cited by 44

Ecological and Evolutionary responses to Antibiotic Treatment in the Human Gut Microbiota

Pennycook, J., & Scanlan, P. D. (2021) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuab018 · Cited by 45

Probiotic-Based Vaccines May Provide Effective Protection against COVID-19 Acute Respiratory Disease

Taghinezhad‐S, S., Mohseni, A. H., Bermúdez‐Humarán, L. G., Casolaro, V., Cortes‐Perez, N. G., Keyvani, H., & Simal‐Gándara, J. (2021) · Vaccines · doi:10.3390/vaccines9050466 · Cited by 46

Microbiome Modulation as a Novel Strategy to Treat and Prevent Respiratory Infections

Mindt, B. C., & DiGiandomenico, A. (2022) · Antibiotics · doi:10.3390/antibiotics11040474 · Cited by 47

Microbiome in Critical Care: An Unconventional and Unknown Ally

Zanza, C., Romenskaya, T., Thangathurai, D., Ojetti, V., Saviano, A., Abenavoli, L., Robba, C., Cammarota, G., Franceschi, F., Piccioni, A., et al. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210915115056 · Cited by 43

Triclosan and triclocarban as potential risk factors of colitis and colon cancer: Roles of gut microbiota involved

Sanidad, K. Z., Wang, G., Panigrahy, A., & Zhang, G. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.156776 · Cited by 43

Effect of endometriosis on the fecal bacteriota composition of mice during the acute phase of lesion formation

Hantschel, J., Weis, S., Schäfer, K., Menger, M. D., Kohl, M., Egert, M., & Laschke, M. W. (2019) · PLoS ONE · doi:10.1371/journal.pone.0226835 · Cited by 43

Using Diverse Model Systems to Define Intestinal Epithelial Defenses to Enteric Viral Infections

Segrist, E., & Cherry, S. R. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.02.003 · Cited by 44

Environmental DNA from multiple pathogens is elevated near active Atlantic salmon farms

Shea, D. W., Bateman, A. W., Li, S., Tabata, A., Schulze, A. D., Mordecai, G. J., Ogston, L., Volpe, J. P., Frazer, L. N., Connors, B. M., et al. (2020) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2020.2010 · Cited by 43

The Impact of Obesity and a High-Fat Diet on Clinical and Immunological Features in Systemic Lupus Erythematosus

Kono, M., Nagafuchi, Y., Shoda, H., & Fujio, K. (2021) · Nutrients · doi:10.3390/nu13020504 · Cited by 45

The role of microbiota in nonalcoholic fatty liver disease

Ciaula, A. D., Bonfrate, L., & Portincasa, P. (2022) · European Journal of Clinical Investigation · doi:10.1111/eci.13768 · Cited by 44

Oral tolerance: an updated review

Rezende, R. M., & Weiner, H. L. (2022) · Immunology Letters · doi:10.1016/j.imlet.2022.03.007 · Cited by 43

Early gut microbiota intervention in premature infants: Application perspectives

Xiang, Q., Yan, X., Shi, W., Li, H., & Zhou, K. (2022) · Journal of Advanced Research · doi:10.1016/j.jare.2022.11.004 · Cited by 49

The Immune Protein Calprotectin Impacts Clostridioides difficile Metabolism through Zinc Limitation

Lopez, C. A., Beavers, W. N., Weiss, A., Knippel, R. J., Zackular, J. P., Chazin, W., & Skaar, E. P. (2019) · mBio · doi:10.1128/mbio.02289-19 · Cited by 42

Development of a Stable Lung Microbiome in Healthy Neonatal Mice

Kostrić, M., Milger, K., Krauss‐Etschmann, S., Engel, M., Vestergaard, G., Schloter, M., & Schöler, A. (2017) · Microbial Ecology · doi:10.1007/s00248-017-1068-x · Cited by 45

Microbiota and Immune-Mediated Skin Diseases—An Overview

Cătinean, A., Neag, M. A., Mitre, A. O., Bocșan, I. C., & Buzoianu, A. D. (2019) · Microorganisms · doi:10.3390/microorganisms7090279 · Cited by 42

Circadian dynamics of the teleost skin immune-microbiome interface

Ellison, A., Wilcockson, D. C., & Cable, J. (2021) · Microbiome · doi:10.1186/s40168-021-01160-4 · Cited by 44

A rapid method for isolation of bacterial extracellular vesicles from culture media using epsilon-poly-L–lysine that enables immunological function research

Wei, S., Jiao, D., & Xing, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.930510 · Cited by 42

Synergistic Interactions Among Microbial Communities

Sarsan, S., Pandiyan, A., Rodhe, A. V., & Jagavati, S. (2021) · Springer eBooks · doi:10.1007/978-981-16-5617-0_1 · Cited by 42

Common themes in antimicrobial and anticancer drug resistance

Chifiriuc, M. C., Filip, R., Constantin, M., Pîrcălăbioru, G. G., Bleoţu, C., Burlibaşa, L., Ionica, E., Corcionivoschi, N., & Mihăescu, G. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.960693 · Cited by 41

Human gut bifidobacteria inhibit the growth of the opportunistic fungal pathogen Candida albicans

Ricci, L., Mackie, J., Donachie, G. E., Chapuis, A. F., Mezerová, K., Lenardon, M. D., Brown, A. J. P., Duncan, S. H., & Walker, A. W. (2022) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiac095 · Cited by 45

Dietary exposure to endocrine disruptors in gut microbiota: A systematic review

Calero-Medina, L., Jiménez-Casquet, M. J., Heras-González, L., Conde-Pipó, J., López-Moro, A., Olea‐Serrano, F., & Mariscal‐Arcas, M. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.163991 · Cited by 43

Engineered extracellular vesicles as a next-generation vaccine platform

Lu, M., Xing, H., Zhao, X., Huang, Y., Zheng, A., & Liang, X. (2024) · Matter · doi:10.1016/j.matt.2024.09.012 · Cited by 42

Human Microbiome as an Immunoregulatory Axis: Mechanisms, Dysbiosis, and Therapeutic Modulation

Cortes, M., Olate, P., Rodríguez, R., Díaz, R., Martínez, A., Hernández, G., Sepúlveda, N., Paz, E. A., & Quiñones, J. (2025) · Microorganisms · doi:10.3390/microorganisms13092147 · Cited by 45

Progress in the understanding of the pathology of allergic asthma and the potential of fruit proanthocyanidins as modulators of airway inflammation

Coleman, S. L., & Shaw, O. M. (2017) · Food & Function · doi:10.1039/c7fo00789b · Cited by 42

Allelic Variation in a Single Genomic Region Alters the Microbiome of the Snail Biomphalaria glabrata

Allan, E. R. O., Tennessen, J. A., Sharpton, T. J., & Blouin, M. S. (2018) · Journal of Heredity · doi:10.1093/jhered/esy014 · Cited by 41

The gut microbiome and frailty

Piggott, D. A., & Tuddenham, S. (2020) · Translational research · doi:10.1016/j.trsl.2020.03.012 · Cited by 43

Endocrine Disruptors and Gut Microbiome Interactions

Hampl, R., & Stárka, L. (2020) · Physiological Research · doi:10.33549/physiolres.934513 · Cited by 43

Effects of endocrine disrupting chemicals in host health: Three-way interactions between environmental exposure, host phenotypic responses, and gut microbiota

Li, N., Li, J., Zhang, Q., Gao, S., Quan, X., Liu, P., & Xu, C. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.116387 · Cited by 41

The Emerging Role of the Innate Immune Response in Idiosyncratic Drug Reactions

Sernoskie, S. C., Jee, A., & Uetrecht, J. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000090 · Cited by 41

Intestinal Microbiota—A Promising Target for Antiviral Therapy?

Yang, M., Yang, Y., He, Q., Zhu, P., Liu, M., Xu, J., & Zhao, M. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.676232 · Cited by 41

Influence of warm acupuncture on gut microbiota and metabolites in rats with insomnia induced by PCPA

Yu, H., Yu, H., Si, L., Meng, H., Chen, W., Wang, Z., & Gula, A. (2022) · PLoS ONE · doi:10.1371/journal.pone.0267843 · Cited by 41

Invited Review: Ruminal microbes, microbial products, and systemic inflammation

Garcia, M., Bradford, B. J., & Nagaraja, T. G. (2017) · The Professional Animal Scientist · doi:10.15232/pas.2017-01663 · Cited by 42

Lactobacillus johnsonii enhances the gut barrier integrity via the interaction between GAPDH and the mouse tight junction protein JAM-2

Bai, Y., Lyu, M., Fukunaga, M., Watanabe, S., Iwatani, S., Miyanaga, K., & Yamamoto, N. (2022) · Food & Function · doi:10.1039/d2fo00886f · Cited by 40

Gut integrity in intensive care: alterations in host permeability and the microbiome as potential therapeutic targets

Oami, T., Shimazui, T., Yumoto, T., Otani, S., Hayashi, Y., & Coopersmith, C. M. (2025) · Journal of Intensive Care · doi:10.1186/s40560-025-00786-y · Cited by 42

Gut Microbiota-Derived Metabolites in Atherosclerosis: Pathways, Biomarkers, and Targets

Tonch-Cerbu, A.-K., Boicean, A., Stoia, O., & Teodoru, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26178488 · Cited by 46

Vancomycin and ceftriaxone can damage intestinal microbiota and affect the development of the intestinal tract and immune system to different degrees in neonatal mice

Cheng, R., Li, M., Li, S. S., He, M., Yu, X. H., Shi, L., & He, F. (2017) · Pathogens and Disease · doi:10.1093/femspd/ftx104 · Cited by 40

Microbiota in cerebrovascular disease: A key player and future therapeutic target

Tonomura, S., Ihara, M., & Friedland, R. P. (2020) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x20918031 · Cited by 41

Human Gut Microbiome and Liver Diseases: From Correlation to Causation

Li, R., Mao, Z., Ye, X., & Zuo, T. (2021) · Microorganisms · doi:10.3390/microorganisms9051017 · Cited by 40

NOD1 in the interplay between microbiota and gastrointestinal immune adaptations

Fernández-García, V., González-Ramos, S., Martín‐Sanz, P., del Portillo, F. G., Laparra, J. M., & Boscá, L. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105775 · Cited by 41

The distribution and function of teleost IgT

Xu, H., Wang, Z., Li, Y., & Xu, Z. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.109281 · Cited by 39

Vaginal and endometrial microbiome dysbiosis associated with adverse embryo transfer outcomes

Su, W., Gong, C., Zhong, H., Yang, H., Chen, Y., Wu, X., Jin, J., Xi, H., & Zhao, J. (2024) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-024-01274-y · Cited by 43

Precise probiotic therapy: Advances, bottlenecks, and the road to microbiome-informed nutrition

Jiang, Y., Jiang, S., Wang, Z., Zhu, P., Zhang, J., Teng, F., & Huang, S. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2623359 · Cited by 41

The remedy within: will the microbiome fulfill its therapeutic promise?

Thaiss, C. A., & Elinav, E. (2017) · Journal of Molecular Medicine · doi:10.1007/s00109-017-1563-z · Cited by 39

Conducting metagenomic studies in microbiology and clinical research

Martin, T. C., Visconti, A., Spector, T. D., & Falchi, M. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-9209-9 · Cited by 40

Diet induced changes in the microbiota and cell composition of rabbit gut associated lymphoid tissue (GALT)

Arrazuria, R., Pérez, V. P., Molina, E., Juste, R. A., Khafipour, E., & Elguezábal, N. (2018) · Scientific Reports · doi:10.1038/s41598-018-32484-1 · Cited by 41

Rheumatoid arthritis reprograms circadian output pathways

Poolman, T. M., Gibbs, J. E., Walker, A. L., Dickson, S. H., Farrell, L. N., Hensman, J. J., Kendall, A. C., Maidstone, R. J., Warwood, S., Loudon, A. S. I., et al. (2019) · Arthritis Research & Therapy · doi:10.1186/s13075-019-1825-y · Cited by 39

Microbiome and Metabolome Profiles Associated With Different Types of Short Bowel Syndrome: Implications for Treatment

Budínská, E., Gojda, J., Heczková, M., Brátová, M., Daňková, H., Wohl, P., Bastova, H., Lánská, V., Kostovčík, M., Dastych, M., et al. (2019) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1595 · Cited by 39

Host-Microbiome Interactions in the Era of Single-Cell Biology

Sharma, P. V., & Thaiss, C. A. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.569070 · Cited by 39

Molecular properties of postbiotics and their role in controlling aquaculture diseases

Sudhakaran, G., Guru, A., Haridevamuthu, B., Murugan, R., Arshad, A., & Arockiaraj, J. (2022) · Aquaculture Research · doi:10.1111/are.15846 · Cited by 41

Glucocorticoids coordinate changes in gut microbiome composition in wild North American red squirrels

Petrullo, L. A., Ren, T., Wu, M., Boonstra, R., Palme, R., Boutin, S. A., McAdam, A. G., & Dantzer, B. (2022) · Scientific Reports · doi:10.1038/s41598-022-06359-5 · Cited by 40

Effect of diet on the gut mycobiome and potential implications in inflammatory bowel disease

Buttar, J., Kon, E., Lee, A. H., Kaur, G., & Lunken, G. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2399360 · Cited by 41

Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity

Cheng, M., Chen, Y., Wang, L., Chen, W., Yang, L., Shen, G., Xu, T., Shen, G., Tian, Z., & Hu, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-08264-8 · Cited by 38

The Association Between Inflammaging and Age-Related Changes in the Ruminal and Fecal Microbiota Among Lactating Holstein Cows

Zhang, G., Wang, Y., Luo, H., Qiu, W., Zhang, H., Hu, L., Wang, Y., Dong, G., & Guo, G. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01803 · Cited by 40

Oral Probiotics Alter Healthy Feline Respiratory Microbiota

Vientós‐Plotts, A. I., Ericsson, A. C., Rindt, H., & Reinero, C. R. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01287 · Cited by 40

The Developing Genome: An Introduction to Behavioral Epigenetics

Pollard, H. B. (2018) · Psychiatry · doi:10.1080/00332747.2018.1502557 · Cited by 38

How gut microbiota may impact ocular surface homeostasis and related disorders

Labétoulle, M., Baudouin, C., del Castillo, J. M. B., Rolando, M., Rescigno, M., Messmer, E. S. B. M., & Aragona, P. (2024) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2024.101250 · Cited by 38

A role for microglia in mediating the microbiota–gut–brain axis

Keane, L., Clarke, G. A., & Cryan, J. F. (2025) · Nature reviews. Immunology · doi:10.1038/s41577-025-01188-9 · Cited by 43

Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders

Velde, A. A. T., Bezema, T., van Kampen, A. H. C., Kraneveld, A. D., Hart, B. A. ‘., van Middendorp, H., Hack, E., van Montfrans, J. M., Belzer, C., Jans-Beken, L., et al. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00587 · Cited by 37

Transdermal Delivery of Living and Biofunctional Probiotics through Dissolvable Microneedle Patches

Chen, H., Lin, D. H., Liu, F., Zhou, L., Liu, D., Lin, Z., Yang, C., Jin, Q., Hang, T., He, G., et al. (2018) · ACS Applied Bio Materials · doi:10.1021/acsabm.8b00102 · Cited by 37

Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation

Jacobs, M. C., Lankelma, J. M., Wolff, N. S., Hugenholtz, F., de Vos, A. F., van der Poll, T., & Wiersinga, W. J. (2020) · PLoS ONE · doi:10.1371/journal.pone.0241748 · Cited by 37

Gut microbiota and the human gut physiological changes

Bajinka, O., Darboe, A., Tan, Y., Abdelhalim, K. A., & Cham, L. B. (2020) · Annals of Microbiology · doi:10.1186/s13213-020-01608-2 · Cited by 39

Positive influence of gut microbiota on the effects of Korean red ginseng in metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial

Seong, E., Bose, S., Han, S.-Y., Song, E., Lee, M.-J., Nam, Y., & Kim, H. (2021) · The EPMA Journal · doi:10.1007/s13167-021-00243-4 · Cited by 37

Stem Cells and Innate Immunity in Aquatic Invertebrates: Bridging Two Seemingly Disparate Disciplines for New Discoveries in Biology

Ballarin, L., Karahan, A., Salvetti, A., Rossi, L., Manni, L., Rinkevich, B., Rosner, A., Voskoboynik, A., Rosental, B., Canesi, L., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.688106 · Cited by 38

Trace metal elements: a bridge between host and intestinal microorganisms

Ma, Y., Fei, Y., Ding, S., Jiang, H., Fang, J. Q., & Liu, G. (2023) · Science China Life Sciences · doi:10.1007/s11427-022-2359-4 · Cited by 39

The Intricate Link among Gut “Immunological Niche,” Microbiota, and Xenobiotics in Intestinal Pathology

Pagliari, D., Gambassi, G., Piccirillo, C. A., & Cianci, R. (2017) · Mediators of Inflammation · doi:10.1155/2017/8390595 · Cited by 38

Fecal Microbiota Transplantation for Treatment of Acute Graft-versus-Host Disease

Shouval, R., Geva, M., Nagler, A., & Youngster, I. (2019) · Clinical Hematology International · doi:10.2991/chi.d.190316.002 · Cited by 37

The Microbiota Contributes to the Control of Highly Pathogenic H5N9 Influenza Virus Replication in Ducks

Figueroa, T., Bessière, P., Coggon, A., Bouwman, K. M., van der Woude, R., Delverdier, M. E., Verheije, M. H., de Vries, R. P., & Volmer, R. (2020) · Journal of Virology · doi:10.1128/jvi.00289-20 · Cited by 41

Vagal sensory pathway for the gut-brain communication

Cao, Y., Li, R., & Bai, L. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.07.009 · Cited by 38

Carboxymethylated Abrus cantoniensis polysaccharide prevents CTX-induced immunosuppression and intestinal damage by regulating intestinal flora and butyric acid content

Hu, H., Sun, W., Zhang, L., Zhang, Y., Kuang, T., Qu, D., Lian, S., Hu, S., Cheng, M., Xu, Y., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.129590 · Cited by 36

NLRP3 inflammasome activation and NETosis positively regulate each other and exacerbate proinflammatory responses: implications of NETosis inhibition for acne skin inflammation treatment

Kim, H. J., Lee, Y. S., Lee, B., Han, C., Kim, S. G., & Kim, C. (2024) · Cellular and Molecular Immunology · doi:10.1038/s41423-024-01137-x · Cited by 36

Faecalibacterium duncaniae as a novel next generation probiotic against influenza

Chollet, L., Heumel, S., Deruyter, L., Bouilloux, F., Delval, L., Robert, V., Gevaert, M.-H., Pichavant, M., Sencio, V., Robil, C., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1347676 · Cited by 39

Standardization in host–microbiota interaction studies: challenges, gnotobiology as a tool, and perspective

Mooser, C., de Agüero, M. G., & Ganal-Vonarburg, S. C. (2018) · Current Opinion in Microbiology · doi:10.1016/j.mib.2018.07.007 · Cited by 37

Microbiome Profiles of Ligature-Induced Periodontitis in Nonhuman Primates across the Life Span

Kirakodu, S. S., Chen, J., González‐Martínez, J., González, O. A., & Ebersole, J. L. (2019) · Infection and Immunity · doi:10.1128/iai.00067-19 · Cited by 36

Early development of the skin microbiome: therapeutic opportunities

Casterline, B. W., & Paller, A. S. (2020) · Pediatric Research · doi:10.1038/s41390-020-01146-2 · Cited by 39

The intestinal microbiota in health and disease: the influence of microbial products on immune cell homeostasis

Abt, M. C., & Artis, D. (2009) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e328331b6b4 · Cited by 111

The Microbes of the Intestine: An Introduction to Their Metabolic and Signaling Capabilities

Hsiao, W., Metz, C. N., Singh, D. P., & Roth, J. (2008) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2008.08.006 · Cited by 84

Deciphering the interdependent labyrinth between gut microbiota and the immune system

Saini, A., Dalal, P., & Sharma, D. (2022) · Letters in Applied Microbiology · doi:10.1111/lam.13775 · Cited by 18

Microbiome and Gut Immunity: Innate Immune Cells

Strowig, T., Thiemann, S., & Diefenbach, A. (2018) · Springer eBooks · doi:10.1007/978-3-319-90545-7_8 · Cited by 9

Bridging intestinal immunity and gut microbiota by metabolites

Wang, G., Huang, S., Wang, Y., Cai, S., Yu, H., Liu, H., Zeng, X., Zhang, G., & Qiao, S. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03190-6 · Cited by 305