The microbiome and innate immunity

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444

Diversity of the Human Intestinal Microbial Flora

Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., DuGar, B., Feldstein, A. E., Britt, E. B., Fu, X., Chung, Y.-M., et al. (2011) · Nature · doi:10.1038/nature09922 · Cited by 5,597

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H., et al. (2001) · Nature · doi:10.1038/35079114 · Cited by 5,030

Richness of human gut microbiome correlates with metabolic markers

Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

Koeth, R. A., Wang, Z., Levison, B. S., Buffa, J. A., Org, E., Sheehy, B. T., Britt, E. B., Fu, X., Wu, Y., Li, L., et al. (2013) · Nature Medicine · doi:10.1038/nm.3145 · Cited by 4,386

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy

Sivan, A., Corrales, L., Hubert, N., Williams, J. B., Aquino-Michaels, K., Earley, Z. M., Benyamin, F. W., Man Lei, Y., Jabri, B., Alegre, M.-L., et al. (2015) · Science · doi:10.1126/science.aac4255 · Cited by 3,888

Type 2 diabetes as an inflammatory disease

Donath, M. Y., & Shoelson, S. E. (2011) · Nature Reviews Immunology · doi:10.1038/nri2925 · Cited by 3,737

Complete Genome Insights into Lactococcus petauri CF11 Isolated from a Healthy Human Gut Using Second- and Third-Generation Sequencing

Ou, Y.-J., Ren, Q., Fang, S., Wu, J., Jiang, Y., Chen, Y.-R., Zhong, Y., Wang, D.-D., & Zhang, G. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00119 · Cited by 24

Differences in Gut Microbiome in Hospitalized Immunocompetent vs. Immunocompromised Children, Including Those With Sickle Cell Disease

Mohandas, S., Soma, V. L., Tran, T. D. B., Sodergren, E. J., Ambooken, T., Goldman, D. L., Weinstock, G. M., & Herold, B. C. (2020) · Frontiers in Pediatrics · doi:10.3389/fped.2020.583446 · Cited by 25

The Emerging Role of Microbiota and Microbiome in Pancreatic Ductal Adenocarcinoma

Čierniková, S., Novisedláková, M., Cholujová, D., Števurková, V., & Mego, M. (2020) · Biomedicines · doi:10.3390/biomedicines8120565 · Cited by 24

Gradients in the in vivo intestinal stem cell compartment and their in vitro recapitulation in mimetic platforms

Malijauskaite, S., Connolly, S. A., Newport, D. T., & McGourty, K. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.03.002 · Cited by 24

Gut Bacterial and Fungal Communities of the Wild and Laboratory-Reared Thitarodes Larvae, Host of the Chinese Medicinal Fungus Ophiocordyceps sinensis on Tibetan Plateau

Liu, G., Zheng, X., Long, H., Rao, Z., Cao, L., & Han, R. (2021) · Insects · doi:10.3390/insects12040327 · Cited by 24

The Gut-Brain-Microbiome Axis and Its Link to Autism: Emerging Insights and the Potential of Zebrafish Models

James, D. M., Davidson, E. A., Yanes, J. A., Moshiree, B., & Dallman, J. E. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.662916 · Cited by 25

Antibiotic Intervention Affects Maternal Immunity During Gestation in Mice

Benner, M., Lopez‐Rincon, A., Thijssen, S., Garssen, J., Ferwerda, G., Joosten, I., Molen, R. G. V. D., & Hogenkamp, A. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.685742 · Cited by 24

Mucosal‐associated invariant T cells: A cryptic coordinator in HIV‐infected immune reconstitution

Su, B., Kong, D., Yang, X., Zhang, T., & Kuang, Y. (2022) · Journal of Medical Virology · doi:10.1002/jmv.27696 · Cited by 24

Gut microbiome in non-alcoholic fatty liver disease associated hepatocellular carcinoma: Current knowledge and potential for therapeutics

Said, I., Ahad, H., & Said, A. (2022) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v14.i5.947 · Cited by 27

Alteration of the gut microbiota’s composition and metabolic output correlates with COVID-19-like severity in obese NASH hamsters

Sencio, V., Benech, N., Robil, C., Deruyter, L., Heumel, S., Machelart, A., Sulpice, T., Lamazière, A., Grangette, C., Briand, F., et al. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2100200 · Cited by 24

Altered gut microbiota in hepatocellular carcinoma: Insights into the pathogenic mechanism and preclinical to clinical findings

Das, B. K. (2022) · Apmis · doi:10.1111/apm.13282 · Cited by 25

Schizophrenia and obesity: May the gut microbiota serve as a link for the pathogenesis?

Wu, H., Liu, Y., Wang, J., Chen, S., Xie, L., & Wu, X. (2023) · iMeta · doi:10.1002/imt2.99 · Cited by 24

Effects of dietary chlorogenic acid on cecal microbiota and metabolites in broilers during lipopolysaccharide-induced immune stress

Hu, X., Zhen, W., Bai, D., Zhong, J., Zhang, R., Zhang, H., Zhang, Y., Ito, K., Zhang, B., & Ma, Y. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1347053 · Cited by 25

Maternal gastrointestinal microbiome shapes gut microbial function and resistome of newborns in a cow-to-calf model

Zhuang, Y., Liu, S., Gao, D., Xu, Y., Jiang, W., Hou, G., Li, S., Zhao, X., Chen, T., Li, S., et al. (2024) · Microbiome · doi:10.1186/s40168-024-01943-5 · Cited by 26

The Gut Microbiota, Tumorigenesis, and Liver Diseases

Lv, G., Cheng, N., & Wang, H. (2017) · Engineering · doi:10.1016/j.eng.2017.01.017 · Cited by 24

Transgenerational effects of paternal dietary Astragalus polysaccharides on spleen immunity of broilers

Li, Y., Lei, X., Yin, Z., Guo, W., Wu, S., & Yang, X. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.04.009 · Cited by 24

Whole Body Vibration-Induced Omental Macrophage Polarization and Fecal Microbiome Modification in a Murine Model

Yu, J. C.-K., Hale, V. L., Khodadadi, H., & Baban, B. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133125 · Cited by 24

The differences of bacterial communities in the tissues between healthy and diseased Yesso scallop (Patinopecten yessoensis)

Yu, Z., Liu, C., Fu, Q., Lu, G., Han, S., Wang, L., & Song, L. (2019) · AMB Express · doi:10.1186/s13568-019-0870-x · Cited by 24

An Integrated Multi-Disciplinary Perspective for Addressing Challenges of the Human Gut Microbiome

Shah, R., McKenzie, E. J., Rosin, M., Jadhav, S. R., Gondalia, S. V., Rosendale, D., & Beale, D. J. (2020) · Metabolites · doi:10.3390/metabo10030094 · Cited by 25

Nutraceuticals and probiotics in the management of psychiatric and neurological disorders: A focus on microbiota-gut-brain-immune axis

Tong, J., Satyanarayanan, S. K., & Su, H. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.08.027 · Cited by 24

Antibiotics, cancer risk and oncologic treatment efficacy: a practical review of the literature

Lopes, M. S. M., Machado, L. M., Silva, P. A. I. A., Uchiyama, A. A. T., Yen, C. T., Ricardo, E. D., Mutão, T. S., Pimento, J. R., Shimba, D. S., Hanriot, R. D. M., et al. (2020) · ecancermedicalscience · doi:10.3332/ecancer.2020.1106 · Cited by 25

Gardenia Jasminoides Ameliorates Antibiotic-Associated Aggravation of DNCB-Induced Atopic Dermatitis by Restoring the Intestinal Microbiome Profile

Kim, H. I., Hong, S. H., Lee, S.-Y., Ku, J. M., Kim, M., & Ko, S. (2021) · Nutrients · doi:10.3390/nu13041349 · Cited by 25

Biogeography of the Relationship between the Child Gut Microbiome and Innate Immune System

Amenyogbe, N., Dimitriu, P. A., Smolen, K. K., Brown, E., Shannon, C. P., Tebbutt, S. J., Cooper, P. J., Marchant, A., Goetghebuer, T., Esser, M., et al. (2021) · mBio · doi:10.1128/mbio.03079-20 · Cited by 23

Immunomodulation by Gut Microbiome on Gastrointestinal Cancers: Focusing on Colorectal Cancer

AL-Ishaq, R. K., Koklesová, L., Kubatka, P., & Büsselberg, D. (2022) · Cancers · doi:10.3390/cancers14092140 · Cited by 23

Crucial nuances in understanding (mis)associations between the neonatal microbiome and Cesarean delivery

Sassin, A. M., Johnson, G. J., Goulding, A. N., & Aagaard, K. M. (2022) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2022.07.005 · Cited by 23

Investigating volatile compounds in the Bacteroides secretome

Shagaleeva, O. Y., Kashatnikova, D. A., Kardonsky, D. A., Konanov, D. N., Efimov, B. A., Bagrov, D. V., Evtushenko, E. G., Chaplin, A. V., Silantiev, A. S., Filatova, J. V., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1164877 · Cited by 23

Current knowledge on the effects of environmental contaminants in early life nutrition

Street, M. E., Shulhai, A.-M., Rotondo, R., Giannì, G., & Caffarelli, C. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1120293 · Cited by 23

Limosilactobacillus johnsoni and Limosilactobacillus mucosae and Their Extracellular Vesicles Alleviate Gut Inflammatory Injury by Mediating Macrophage Polarization in a Lipopolysaccharide-Challenged Piglet Model

Li, J., Feng, S., Pi, Y., Jiang, X., Li, X., Zhou, Z., Liu, X., Wei, H., & Tao, S. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.06.009 · Cited by 23

Characterization of the bacterial microbiome of non-hematophagous bats and associated ectoparasites from Brazil

André, M. R., Ikeda, P., Lee, D. A. B., do Amaral, R. B., de Carvalho, L. A. L., Pinheiro, D. G., Torres, J. M., de Mello, V. V. C., Rice, G. K., Cer, R. Z., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1261156 · Cited by 23

The Role of the Innate Immune Response in Oral Mucositis Pathogenesis

Bowen, J. M., & Cross, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216314 · Cited by 23

The link between obesity and the gut microbiota and immune system in early-life

Magalhães, I., Azevedo, M. J., Castro, F., Oliveira, M. J., Costa, Â. M., & Sampaio‐Maia, B. (2024) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2024.2342427 · Cited by 23

Spotted Gar and the Evolution of Innate Immune Receptors

Wcisel, D. J., Ota, T., Litman, G. W., & Yoder, J. A. (2017) · Journal of Experimental Zoology Part B Molecular and Developmental Evolution · doi:10.1002/jez.b.22738 · Cited by 23

Interaction between Insects, Toxins, and Bacteria: Have We Been Wrong So Far?

Tetreau, G. (2018) · Toxins · doi:10.3390/toxins10070281 · Cited by 23

The correlation between intestinal dysbiosis and the development of ankylosing spondylitis

Zhang, L., Hu, Y., Yao, X., Li, P., Ma, H., Li, X., & Li, M. (2019) · Microbial Pathogenesis · doi:10.1016/j.micpath.2019.04.038 · Cited by 23

The Role of the Microbiota in the Diabetic Peripheral Artery Disease

Biscetti, F., Nardella, E., Cecchini, A. L., Landolfi, R., & Flex, A. (2019) · Mediators of Inflammation · doi:10.1155/2019/4128682 · Cited by 23

NOD1 deficiency promotes an imbalance of thyroid hormones and microbiota homeostasis in mice fed high fat diet

González-Ramos, S., Paz-García, M., Fernández-García, V., Portune, K. J., Acosta-Medina, E. F., Sanz, Y., Castrillo, A., Martín‐Sanz, P., Obregón, M.-J., & Boscá, L. (2020) · Scientific Reports · doi:10.1038/s41598-020-69295-2 · Cited by 24

Emerging Roles for the Gut Microbiome in Lymphoid Neoplasms

Shi, Z., & Zhang, M. (2021) · Clinical Medicine Insights Oncology · doi:10.1177/11795549211024197 · Cited by 23

Unraveling the gut microbiota’s role in Rheumatoid arthritis: dietary pathways to modulation and therapeutic potential

Shan, L., Chelliah, R., Rahman, S. M. E., & Oh, D. H. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2024.2362412 · Cited by 22

Sex differences and testosterone interfere with the structure of the gut microbiota through the bile acid signaling pathway

Duan, X., Nie, Y., Xie, X., Zhang, Q., Zhu, C., Zhu, H., Chen, R., Xu, J. J., Zhang, J., Yang, C., et al. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1421608 · Cited by 23

Alcaligenes faecalis promotes colitis to colorectal cancer transition through IgA+ B cell suppression and vinculin acetylation

Zheng, J., Zhou, C., Li, Z., Jin, X., Zou, Y., Bai, S., Zheng, H., Ling, W., Zhao, Y. C., Wang, Y., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2473511 · Cited by 22

Live Biotherapeutic Products for Metabolic Diseases: Development Strategies, Challenges, and Future Directions

Min, H., Choi, K.-S., Yun, S., & Jang, S. (2025) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2410.10054 · Cited by 26

Herbal Medicine, Gut Microbiota, and COVID-19

Chen, Z., Lv, Y., Xu, H., & Deng, L. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.646560 · Cited by 22

miRNAs in the Regulation of Cancer Immune Response: Effect of miRNAs on Cancer Immunotherapy

Pottoo, F. H., Iqubal, A., Iqubal, M. K., Salahuddin, M., Rahman, J. U., Alhajri, N., & Shehadeh, M. (2021) · Cancers · doi:10.3390/cancers13236145 · Cited by 22

The cure from within? a review of the microbiome and diet in melanoma

Kumar, P. R., Brazel, D., DeRogatis, J. M., Goldstein, J. B., Whiteson, K., Chow, W. A., Tinoco, R., & Moyers, J. T. (2022) · Cancer and Metastasis Reviews · doi:10.1007/s10555-022-10029-3 · Cited by 22

Uncovering the core principles of the gut-lung axis to enhance innate immunity in the chicken

Saint-Martin, V., Quéré, P., Trapp, S., & Guabiraba, R. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.956670 · Cited by 22

Microbiome-metabolome analysis reveals alterations in the composition and metabolism of caecal microbiota and metabolites with dietary Enteromorpha polysaccharide and Yeast glycoprotein in chickens

Wassie, T., Cheng, B., Zhou, T., Gao, L., Lu, Z., Xie, C., & Wu, X. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.996897 · Cited by 22

Microplastics’ and Nanoplastics’ Interactions with Microorganisms: A Bibliometric Study

Grande‐Tovar, C. D., Carrascal-Hernández, D. C., Trilleras, J. E., Mora, K., & Arana, V. A. (2022) · Sustainability · doi:10.3390/su142214761 · Cited by 23

The Correlation between Periodontal Parameters and Cell-Free DNA in the Gingival Crevicular Fluid, Saliva, and Plasma in Chinese Patients: A Cross-Sectional Study

Zhu, X., Chu, C.-J., Pan, W., Li, Y., Huang, H., & Жао, Л. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11236902 · Cited by 22

Homemade blenderized tube feeding improves gut microbiome communities in children with enteral nutrition

Katagiri, S., Ohsugi, Y., Shiba, T., Yoshimi, K., Nakagawa, K., Nagasawa, Y., Uchida, A., Liu, A., Lin, P., Tsukahara, Y., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1215236 · Cited by 25

RNA methylation: A potential therapeutic target in autoimmune disease

Li, L., Xia, X., Yang, T. Z., Sun, Y., Liu, X., Xu, W., Lu, M., Cui, D., & Wu, Y. (2023) · International Reviews of Immunology · doi:10.1080/08830185.2023.2280544 · Cited by 24

Live and Heat-Inactivated Streptococcus thermophilus MN-ZLW-002 Mediate the Gut–Brain Axis, Alleviating Cognitive Dysfunction in APP/PS1 Mice

Zhang, Y., Wang, Y., Zhou, Z., Yang, Y., Zhao, J., Kang, X., Li, Z., Shen, X. P., He, F., & Cheng, R. (2024) · Nutrients · doi:10.3390/nu16060844 · Cited by 23

Promising probiotic-fermented soymilk for alleviating acute diarrhea: insights into the microbiome and metabolomics

Madjirebaye, P., Peng, Z., Mueed, A., Huang, T., Peng, F., Allasra, Y., Benar, M. E., Hu, Z., Xie, M., & Xiong, T. (2024) · Food & Function · doi:10.1039/d3fo05690b · Cited by 22

Controlling Candida : immune regulation of commensal fungi in the gut

Jensen, O., Trujillo, E. N., Hanson, L., & Ost, K. S. (2024) · Infection and Immunity · doi:10.1128/iai.00516-23 · Cited by 23

Innate Immune Responses to Fungal Allergens

Portnoy, J. M., Williams, P. B., & Barnes, C. S. (2016) · Current Allergy and Asthma Reports · doi:10.1007/s11882-016-0643-4 · Cited by 23

Determining risk of severe gastrointestinal toxicity based on pretreatment gut microbial community in patients receiving cancer treatment: a new predictive strategy in the quest for personalized cancer medicine

Wardill, H. R., & Tissing, W. J. E. (2017) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000265 · Cited by 23

The Role of High-Mobility Group Box-1 and Its Crosstalk with Microbiome in Rheumatoid Arthritis

Biscetti, F., Flex, A., Alivernini, S., Tolusso, B., Gremese, E., & Ferraccioli, G. (2017) · Mediators of Inflammation · doi:10.1155/2017/5230374 · Cited by 23

Diel patterning in the bacterial community associated with the sea anemone Nematostella vectensis

Leach, W. B., Carrier, T. J., & Reitzel, A. M. (2019) · Ecology and Evolution · doi:10.1002/ece3.5534 · Cited by 22

The link “Cancer and autoimmune diseases” in the light of microbiota: Evidence of a potential culprit

Niccolai, E., Boem, F., Emmi, G., & Amedei, A. (2020) · Immunology Letters · doi:10.1016/j.imlet.2020.03.001 · Cited by 23

The effects of sodium butyrate and high-performance inulin supplementation on the promotion of gut bacterium Akkermansia muciniphila growth and alterations in miR-375 and KLF5 expression in type 2 diabetic patients: A randomized, double-blind, placebo-controlled trial

Roshanravan, N., Mahdavi, R., Jafarabadi, M. A., Alizadeh, E., Ghavami, A., Saadat, Y. R., Alamdari, N. M., Dastourı, M., Alipour, S., & Ostadrahimi, A. (2018) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2017.12.011 · Cited by 23

Regulating colonic dendritic cells by commensal glycosylated large surface layer protein A to sustain gut homeostasis against pathogenic inflammation

Ge, Y., Gong, M., Zadeh, M., Li, J., Abbott, J. R., Li, W., Morel, L. M., Sonon, R. N., Supekar, N. T., Azadi, P., et al. (2019) · Mucosal Immunology · doi:10.1038/s41385-019-0210-0 · Cited by 24

Malnutrition and Its Influence on Gut sIgA–Microbiota Dynamics

Profir, M., Enache, R. M., Roşu, O. A., Pavelescu, L. A., Creţoiu, S. M., & Gașpar, B. S. (2025) · Biomedicines · doi:10.3390/biomedicines13010179 · Cited by 22

Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways

Zhang, W. K., Li, Z., Yang, H., Wang, G., Liu, G., Wang, Y., Bello, B. K., Zhao, P., Liang, W., & Dong, J. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.691445 · Cited by 21

A Class IIb Bacteriocin Plantaricin NC8 Modulates Gut Microbiota of Different Enterotypes in vitro

Pu, J., Hang, S., Liu, M., Chen, Z., Xiong, J., Li, Y., Wu, H., Zhao, X., Liu, S., Gu, Q., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.877948 · Cited by 21

Links between host genetics, metabolism, gut microbiome and amoebic gill disease (AGD) in Atlantic salmon

Schaal, P., Cheaib, B. A., Kaufmann, J., Phillips, K. P., Ryder, L., McGinnity, P., & Llewellyn, M. S. (2022) · Animal Microbiome · doi:10.1186/s42523-022-00203-x · Cited by 23

The gut microbiota regulates acute foreign body reaction and tissue repair after biomaterial implantation

Chen, S.-L., Lundy, D. J., Ruan, S., Chen, H.-C., Chao, Y.-K., Cheng, Y., Prajnamitra, R. P., Liao, C.-C., Lin, C., Lai, J. J., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121807 · Cited by 21

Nanomedicines targeting activation of STING to reshape tumor immune microenvironment and enhance immunotherapeutic efficacy

Chen, S., Peng, A., Chen, M., & Zhan, M. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2022.1093240 · Cited by 22

Microbial–Immune Crosstalk in Elderly-Onset Inflammatory Bowel Disease: Unchartered Territory

Meng, G., Monaghan, T. M., Duggal, N. A., Tighe, P., & Peerani, F. (2023) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjad025 · Cited by 21

Procedures in Fecal Microbiota Transplantation for Treating Irritable Bowel Syndrome: Systematic Review and Meta-Analysis

Rodrigues, T., Fialho, S. R., Araújo, J. R., Rocha, R., & Moreira-Rosário, A. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12051725 · Cited by 21

Undernutrition Disrupts Cecal Microbiota and Epithelium Interactions, Epithelial Metabolism, and Immune Responses in a Pregnant Sheep Model

Wu, W., Lu, H., Cheng, J., Geng, Z., Mao, S., & Xue, Y. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.05320-22 · Cited by 21

Causal inference on microbiome-metabolome relations in observational host-microbiome data via in silico in vivo association pattern analyses

Hertel, J., Heinken, A., Fässler, D., & Thiele, I. (2023) · Cell Reports Methods · doi:10.1016/j.crmeth.2023.100615 · Cited by 21

Mechanism of Qizhen decoction-mediated maturation of DC cells to activate the IL-12/JAK2/STAT4 pathway to sensitise PD-1 inhibitors in the treatment of colorectal cancer

Kong, X., Li, Q., Wang, D., Wang, M., Yang, F., & Meng, J. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.117399 · Cited by 21

Low-protein diet supplemented with 1% L-glutamine improves growth performance, serum biochemistry, redox status, plasma amino acids, and alters fecal microbiota in weaned piglets

Li, J., Bai, J., Yang, Y., & Wu, Z. (2024) · Animal nutrition · doi:10.1016/j.aninu.2023.12.009 · Cited by 21

Acute gastrointestinal permeability after traumatic brain injury in mice precedes a bloom in Akkermansia muciniphila supported by intestinal hypoxia

DeSana, A. J., Estus, S., Barrett, T. A., & Saatman, K. E. (2024) · Scientific Reports · doi:10.1038/s41598-024-53430-4 · Cited by 21

Microecological regulation in HCC therapy: Gut microbiome enhances ICI treatment

Liu, X., Li, S., Wang, L., & Ma, K. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167230 · Cited by 21

Lysosome‐Targeting Bacterial Outer Membrane Vesicles for Tumor Specific Degradation of PD‐L1

Ji, P., Wu, P., Wang, L., Wang, Y., Guo, X., Gao, R., Guo, Z., Zhou, H., Liu, Z., Liang, Y., et al. (2024) · Small · doi:10.1002/smll.202400770 · Cited by 21

Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats

Ruan, M., Bu, Y., Wu, F., Zhang, S., Chen, R., Li, N., Liu, Z., & Wang, H. (2020) · Food Science and Human Wellness · doi:10.1016/j.fshw.2020.06.005 · Cited by 21

Gut Microbiome Profiles and Associated Metabolic Pathways in HIV-Infected Treatment-Naïve Patients

do Nascimento, W. M., Machiavelli, A., Ferreira, L. G. E., Silveira, L. C., de Azevedo, S. S. D., Bello, G., Smith, D. P., Mezzari, M. P., Petrosino, J. F., Duarte, R. T. D., et al. (2021) · Cells · doi:10.3390/cells10020385 · Cited by 21

Lactobacillus reuteri CCFM1072 and CCFM1040 with the role of Treg cells regulation alleviate airway inflammation through modulating gut microbiota in allergic asthma mice

Li, L., Fang, Z., Liu, Z., Zhao, J., Zhang, H., Wang, S., He, J., Lu, W., & Chen, W. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104286 · Cited by 21

Analyzing Large Microbiome Datasets Using Machine Learning and Big Data

Krause, T., Wassan, J. T., Kevitt, P. M., Wang, H., Zheng, H., & Hemmje, M. (2021) · BioMedInformatics · doi:10.3390/biomedinformatics1030010 · Cited by 21

Probiotics in Citrus Fruits Products: Health Benefits and Future Trends for the Production of Functional Foods—A Bibliometric Review

Monteiro, S. S., de Oliveira, V. M., & Pasquali, M. A. D. B. (2022) · Foods · doi:10.3390/foods11091299 · Cited by 21

Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction

Sun, S., Hodel, M., Wang, X., de Vicente, J., Haritunians, T., Debebe, A., Hung, C., Ma, C., Malique, A., Nguyen, H. N., et al. (2024) · Science Immunology · doi:10.1126/sciimmunol.adi7907 · Cited by 21

Gut microbiome and obesity care: Bridging dietary, surgical, and pharmacological interventions

Masi, D., Watanabe, M., & Clément, K. (2026) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102573 · Cited by 22

Impacts of Amino Acids on the Intestinal Defensive System

Ren, W., Bin, P., Yin, Y., & Wu, G. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-45328-2_8 · Cited by 21

Intestinal fungi and systemic autoimmune diseases

Wang, H., Wu, H., Li, K., Wang, Y., Huang, R., Du, Y., Xue, J., Zhang, Q., Li, X., & Li, B. (2022) · Autoimmunity Reviews · doi:10.1016/j.autrev.2022.103234 · Cited by 20

Future foods, dietary factors and healthspan

Li, K., Wang, C., Wang, Y., Fu, L., & Zhang, N. (2023) · Journal of Future Foods · doi:10.1016/j.jfutfo.2022.12.001 · Cited by 20

The impact of microbiome dysbiosis on T cell function within the tumor microenvironment (TME)

DiPalma, M. P., & Blattman, J. N. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1141215 · Cited by 21

Gut microbiome plays a vital role in post-stroke injury repair by mediating neuroinflammation

Huang, A., Ji, L., Li, Y., Li, Y., & Yu, Q. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110126 · Cited by 20

Employing pigs to decipher the host genetic effect on gut microbiome: advantages, challenges, and perspectives

Huang, L., & Chen, C. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2205410 · Cited by 21

Bile acid‐activated receptors in innate and adaptive immunity: targeted drugs and biological agents

Cheung, K. C. P., Ma, J., Loiola, R. A., Chen, X., & Jia, W. P. (2023) · European Journal of Immunology · doi:10.1002/eji.202250299 · Cited by 22

Factors shaping the gut microbiome of five species of lizards from different habitats

Vasconcelos, D. S., Harris, D. J., Damas‐Moreira, I., Pereira, A. M., & Xavier, R. (2023) · PeerJ · doi:10.7717/peerj.15146 · Cited by 20

Influences of continuous and pulse atrazine exposure on intestinal flora and metabolites of Pelophylax nigromaculatus tadpoles

Huang, M., Yin, J., Dai, F., Cao, S., Duan, R., Huang, W., & Zhang, Y. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.165757 · Cited by 20

Piezo1 in Digestive System Function and Dysfunction

He, J., Xie, X., Xiao, Z., Qian, W., Zhang, L., & Hou, X. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612953 · Cited by 21

Cross-talk between biometal ions and immune cells for bone repair

Liu, S., Lin, Z., Qiao, W., Chen, B., & Shen, J. (2024) · Engineered Regeneration · doi:10.1016/j.engreg.2024.01.003 · Cited by 20

Stopover habitat selection drives variation in the gut microbiome composition and pathogen acquisition by migrating shorebirds

Włodarczyk, R., Drzewińska‐Chańko, J., Kamiński, M., Meissner, W., Rapczyński, J., Janik-Superson, K., Krawczyk, D., Strapagiel, D., Ożarowska, A., Stępniewska, K., et al. (2024) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiae040 · Cited by 21

Oral microbiome dysbiosis and gastrointestinal diseases: a narrative review

El-Ghannam, M., Hassanien, M. H., Ameen, Y. A., Turky, E. A., ELattar, G. M., Ray, A. A. E., & Eltalkawy, M. D. (2024) · Egyptian Liver Journal · doi:10.1186/s43066-024-00340-9 · Cited by 20

Mechanisms of intestinal dysbiosis: new insights into tuft cell functions

Coutry, N., Gasmi, I., Herbert, F., & Jay, P. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2379624 · Cited by 20

Metabolic immaturity and breastmilk bile acid metabolites are central determinants of heightened newborn vulnerability to norovirus diarrhea

Peiper, A. M., Aparicio, J. M., Hu, Z., Phophi, L., Helm, E. W., Rubinstein, R., Phillips, M. B., Williams, C. G., Subramanian, S., Cross, M., et al. (2024) · Cell Host & Microbe · doi:10.1016/j.chom.2024.08.003 · Cited by 21

Group 2 ILC s: A way of enhancing immune protection against human helminths?

Nausch, N., & Mutapi, F. (2017) · Parasite Immunology · doi:10.1111/pim.12450 · Cited by 22

25-Hydroxyvitamin D3 Alleviates Experimental Periodontitis via Promoting Expression of Cathelicidin in Mice with Type 2 Diabetic Mellitus

Zhou, X., Zhang, P., Wang, Q., Xia, S., Ji, N., Ding, Y., & Wang, Q. (2018) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.64.307 · Cited by 20

Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress

Li, C., Liu, Q., & Xie, L. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.10.132 · Cited by 20

The intestinal microbiota in health and disease: the influence of microbial products on immune cell homeostasis

Abt, M. C., & Artis, D. (2009) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e328331b6b4 · Cited by 111

The Microbes of the Intestine: An Introduction to Their Metabolic and Signaling Capabilities

Hsiao, W., Metz, C. N., Singh, D. P., & Roth, J. (2008) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2008.08.006 · Cited by 84

Deciphering the interdependent labyrinth between gut microbiota and the immune system

Saini, A., Dalal, P., & Sharma, D. (2022) · Letters in Applied Microbiology · doi:10.1111/lam.13775 · Cited by 18

Microbiome and Gut Immunity: Innate Immune Cells

Strowig, T., Thiemann, S., & Diefenbach, A. (2018) · Springer eBooks · doi:10.1007/978-3-319-90545-7_8 · Cited by 9

Bridging intestinal immunity and gut microbiota by metabolites

Wang, G., Huang, S., Wang, Y., Cai, S., Yu, H., Liu, H., Zeng, X., Zhang, G., & Qiao, S. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03190-6 · Cited by 305