The microbiome and innate immunity

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444

Diversity of the Human Intestinal Microbial Flora

Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., DuGar, B., Feldstein, A. E., Britt, E. B., Fu, X., Chung, Y.-M., et al. (2011) · Nature · doi:10.1038/nature09922 · Cited by 5,597

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H., et al. (2001) · Nature · doi:10.1038/35079114 · Cited by 5,030

Richness of human gut microbiome correlates with metabolic markers

Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

Koeth, R. A., Wang, Z., Levison, B. S., Buffa, J. A., Org, E., Sheehy, B. T., Britt, E. B., Fu, X., Wu, Y., Li, L., et al. (2013) · Nature Medicine · doi:10.1038/nm.3145 · Cited by 4,386

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy

Sivan, A., Corrales, L., Hubert, N., Williams, J. B., Aquino-Michaels, K., Earley, Z. M., Benyamin, F. W., Man Lei, Y., Jabri, B., Alegre, M.-L., et al. (2015) · Science · doi:10.1126/science.aac4255 · Cited by 3,888

Type 2 diabetes as an inflammatory disease

Donath, M. Y., & Shoelson, S. E. (2011) · Nature Reviews Immunology · doi:10.1038/nri2925 · Cited by 3,737

Pattern recognition receptors in health and diseases

Li, D., & Wu, M. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00687-0 · Cited by 1,961

Dysbiosis and the immune system

Levy, M., Kolodziejczyk, A. A., Thaiss, C. A., & Elinav, E. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.7 · Cited by 1,769

Signals from the gut microbiota to distant organs in physiology and disease

Schroeder, B. O., & Bäckhed, F. (2016) · Nature Medicine · doi:10.1038/nm.4185 · Cited by 1,409

Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism

Gao, J., Xu, K., Liu, H., Liu, G., Bai, M., Peng, C., Li, T., & Yin, Y. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00013 · Cited by 1,357

Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome

Ferretti, P., Pasolli, E., Tett, A., Asnicar, F., Gorfer, V., Fedi, S., Armanini, F., Truong, D. T., Manara, S., Zolfo, M., et al. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.06.005 · Cited by 1,292

Homeostatic Immunity and the Microbiota

Belkaid, Y., & Harrison, O. J. (2017) · Immunity · doi:10.1016/j.immuni.2017.04.008 · Cited by 1,261

Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

Wang, X., Sun, G., Feng, T., Zhang, J., Huang, X., Wang, T., Xie, Z., Chu, X., Yang, J., Wang, H., et al. (2019) · Cell Research · doi:10.1038/s41422-019-0216-x · Cited by 1,144

COVID-19: immunopathogenesis and Immunotherapeutics

Li, Y., Liu, S., Liu, J., Zhang, Z., Wan, X., Huang, B., Chen, Y., & Zhang, Y. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00243-2 · Cited by 962

The Human Microbiota in Health and Disease

Wang, B., Yao, M., Lv, L., Ling, Z., & Li, L. (2017) · Engineering · doi:10.1016/j.eng.2017.01.008 · Cited by 916

The Human Gut Microbiome: From Association to Modulation

Schmidt, T. S. B., Raes, J., & Bork, P. (2018) · Cell · doi:10.1016/j.cell.2018.02.044 · Cited by 845

Disentangling Interactions in the Microbiome: A Network Perspective

Layeghifard, M., Hwang, D. M., & Guttman, D. S. (2016) · Trends in Microbiology · doi:10.1016/j.tim.2016.11.008 · Cited by 863

Mechanisms and consequences of intestinal dysbiosis

Weiss, G. A., & Hennet, T. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2509-x · Cited by 775

Human gut microbiota in health and disease: Unveiling the relationship

Afzaal, M., Saeed, F., Shah, Y. A., Hussain, M., Rabail, R., Socol, C. T., Hassoun, A., Pateiro, M., Lorenzo, J. M., Rusu, A. V., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.999001 · Cited by 762

The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease

Yang, T., Richards, E. M., Pepine, C. J., & Raizada, M. K. (2018) · Nature Reviews Nephrology · doi:10.1038/s41581-018-0018-2 · Cited by 753

Environmental factors shaping the gut microbiome in a Dutch population

Gacesa, R., Kurilshikov, A., Vich Vila, A., Sinha, T., Klaassen, M. A. Y., Bolte, L. A., Andreu-Sánchez, S., Chen, L., Collij, V., Hu, S., et al. (2022) · Nature · doi:10.1038/s41586-022-04567-7 · Cited by 735

Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

He, Y., Fu, L., Li, Y., Wang, W., Gong, M., Zhang, J., Dong, X., Huang, J., Wang, Q., Mackay, C. R., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.03.002 · Cited by 729

Biomaterials: Foreign Bodies or Tuners for the Immune Response?

Mariani, E., Lisignoli, G., Borzì, R. M., & Pulsatelli, L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030636 · Cited by 706

Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes

Scheithauer, T. P. M., Rampanelli, E., Nieuwdorp, M., Vallance, B. A., Verchere, C. B., van Raalte, D. H., & Herrema, H. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.571731 · Cited by 715

Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence

Kerr, J., Anderson, C. A. M., & Lippman, S. M. (2017) · The Lancet Oncology · doi:10.1016/s1470-2045(17)30411-4 · Cited by 706

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

Bárcena, C., Valdés-Mas, R., Mayoral, P., Garabaya, C., Durand, S., Rodríguez, F., Fernández-García, M. T., Salazar, N., Nogacka, A. M., Garatachea, N., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0504-5 · Cited by 661

Effects of environmental pollutants on gut microbiota

Jin, Y., Wu, S., Zeng, Z., & Fu, Z. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2016.11.045 · Cited by 683

Antimicrobial Properties of Chitosan and Chitosan Derivatives in the Treatment of Enteric Infections

Yan, D., Li, Y., Liu, Y., Li, N., Zhang, X., & Yan, C. (2021) · Molecules · doi:10.3390/molecules26237136 · Cited by 656

Microbial Ecology along the Gastrointestinal Tract

Hillman, E. T., Lu, H., Yao, T., & Nakatsu, C. H. (2017) · Microbes and Environments · doi:10.1264/jsme2.me17017 · Cited by 614

The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies

Wiertsema, S. P., van Bergenhenegouwen, J., Garssen, J., & Knippels, L. M. J. (2021) · Nutrients · doi:10.3390/nu13030886 · Cited by 590

Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut

Vaccaro, A., Kaplan Dor, Y., Nambara, K., Pollina, E. A., Lin, C., Greenberg, M. E., & Rogulja, D. (2020) · Cell · doi:10.1016/j.cell.2020.04.049 · Cited by 541

Aspects of Gut Microbiota and Immune System Interactions in Infectious Diseases, Immunopathology, and Cancer

Lazăr, V., Diţu, L.-M., Pîrcălăbioru, G. G., Gheorghe, I., Curuțiu, C., Holban, A. M., Picu, A. A., Petcu, L. M., & Chifiriuc, M. C. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01830 · Cited by 552

The hologenome concept of evolution after 10 years

ROSENBERG, E. B., & Zilber‐Rosenberg, I. (2018) · Microbiome · doi:10.1186/s40168-018-0457-9 · Cited by 566

Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

Takenaka, M. C., Gabriely, G., Rothhammer, V., Mascanfroni, I. D., Wheeler, M. A., Chao, C.-C., Gutiérrez-Vázquez, C., Kenison, J., Tjon, E. C., Barroso, A., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0370-y · Cited by 517

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

Chao, Y., Xu, L., Liang, C., Feng, L., Xu, J., Dong, Z., Tian, L., Yi, X., Yang, K., & Liu, Z. (2018) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0262-6 · Cited by 493

Healthy infants harbor intestinal bacteria that protect against food allergy

Feehley, T., Plunkett, C. H., Bao, R., Hong, S. M. C., Culleen, E., Belda‐Ferre, P., Campbell, E., Aitoro, R., Nocerino, R., Paparo, L., et al. (2019) · Nature Medicine · doi:10.1038/s41591-018-0324-z · Cited by 485

Nutritional Components in Western Diet Versus Mediterranean Diet at the Gut Microbiota–Immune System Interplay. Implications for Health and Disease

Montero, C. G., Fraile‐Μartinez, O., Gomez-Lahoz, A. M., Pekarek, L., Castellanos, A. J., Noguerales-Fraguas, F., Coca, S., Guijarro, L. G., García‐Honduvilla, N., Asúnsolo, Á., et al. (2021) · Nutrients · doi:10.3390/nu13020699 · Cited by 487

The Structure of Dental Plaque Microbial Communities in the Transition from Health to Dental Caries and Periodontal Disease

Valm, A. M. (2019) · Journal of Molecular Biology · doi:10.1016/j.jmb.2019.05.016 · Cited by 450

Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health

Lu, L., Luo, T., Zhao, Y., Cai, C., Fu, Z., & Jin, Y. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.02.380 · Cited by 431

Inflammatory and Microbiota-Related Regulation of the Intestinal Epithelial Barrier

Barbara, G., Barbaro, M. R., Fuschi, D., Palombo, M., Falangone, F., Cremon, C., Marasco, G., & Stanghellini, V. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.718356 · Cited by 446

Pathogenesis of allergic diseases and implications for therapeutic interventions

Wang, J., Zhou, Y., Zhang, H., Hu, L., Liu, J., Wang, L., Wang, T., Zhang, H., Cong, L., & Wang, Q. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01344-4 · Cited by 431

Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy

Li, A., Yi, M., Qin, S., Song, Y., Chu, Q., & Wu, K. (2019) · Journal of Hematology & Oncology · doi:10.1186/s13045-019-0721-x · Cited by 413

Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

Zhu, X., Chen, Z., Shen, W., Huang, G., Sedivy, J. M., Wang, H., & Ju, Z. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00646-9 · Cited by 425

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine

Bel, S., Pendse, M., Wang, Y., Li, Y., Ruhn, K. A., Hassell, B., Leal, T., Winter, S. E., Xavier, R. J., & Hooper, L. V. (2017) · Science · doi:10.1126/science.aal4677 · Cited by 396

The role of microbial amyloid in neurodegeneration

Friedland, R. P., & Chapman, M. R. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006654 · Cited by 398

Trace Amines and Their Receptors

Gainetdinov, R. R., Hoener, M. C., & Berry, M. D. (2018) · Pharmacological Reviews · doi:10.1124/pr.117.015305 · Cited by 398

Prebiotics and Probiotics in Digestive Health

Quigley, E. M. M. (2018) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2018.09.028 · Cited by 404

Modulators of mercury risk to wildlife and humans in the context of rapid global change

Eagles‐Smith, C. A., Silbergeld, E. K., Basu, N., Paco Bustamante, A., Díaz‐Barriga, F., Hopkins, W. A., Kidd, K. A., & Nyland, J. F. (2018) · AMBIO · doi:10.1007/s13280-017-1011-x · Cited by 393

B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids

Sanchez, H. N., Moroney, J. B., Gan, H., Shen, T., Im, J. L., Li, T., Taylor, J. R., Zan, H., & Casali, P. (2020) · Nature Communications · doi:10.1038/s41467-019-13603-6 · Cited by 369

The Gut Microbiome Is Associated with Clinical Response to Anti–PD-1/PD-L1 Immunotherapy in Gastrointestinal Cancer

Peng, Z., Cheng, S., Kou, Y., Wang, Z., Jin, R., Hu, H., Zhang, X., Gong, J.-F., Li, J., Lu, M., et al. (2020) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-19-1014 · Cited by 361

Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production

Sencio, V., Barthélémy, A., Tavares, L. P., Machado, M. G., Soulard, D., Cuinat, C., Queiroz‐Junior, C. M., Noordine, M.-L., Salomé‐Desnoulez, S., Deryuter, L., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.02.013 · Cited by 367

The interaction of innate immune and adaptive immune system

Wang, R., Lan, C., Benlagha, K., Câmara, N. O. S., Miller, H. E., Kubo, M., Heegaard, S., Lee, P. P. W., Yang, L., Forsman, H. F., et al. (2024) · MedComm · doi:10.1002/mco2.714 · Cited by 395

Microbiome-modulated metabolites at the interface of host immunity

Blacher, E., Levy, M., Tatirovsky, E., & Elinav, E. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1601247 · Cited by 354

Loss of Gut Microbiota Alters Immune System Composition and Cripples Postinfarction Cardiac Repair

Tang, T. W. H., Chen, H.-C., Chen, C.-Y., Yen, C. Y. T., Lin, C.-J., Prajnamitra, R. P., Chen, L.-L., Ruan, S.-C., Lin, J.-H., Lin, P.-J., et al. (2019) · Circulation · doi:10.1161/circulationaha.118.035235 · Cited by 348

Gut Microbiome Dysbiosis and Immunometabolism: New Frontiers for Treatment of Metabolic Diseases

Belizário, J. E., Faintuch, J., & Garay-Malpartida, M. (2018) · Mediators of Inflammation · doi:10.1155/2018/2037838 · Cited by 341

Interaction of dietary polyphenols and gut microbiota: Microbial metabolism of polyphenols, influence on the gut microbiota, and implications on host health

Çatalkaya, G., Venema, K., Lucini, L., Rocchetti, G., Delmas, D., Daglia, M., Filippis, A. D., Xiao, H., Quiles, J. L., Xiao, J., et al. (2020) · Food Frontiers · doi:10.1002/fft2.25 · Cited by 349

Key players in the immune response to biomaterial scaffolds for regenerative medicine

Chung, L., Maestas, D. R., Housseau, F., & Elisseeff, J. H. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.07.006 · Cited by 333

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

Lee, S.-H., Cho, S.-Y., Yoon, Y., Park, C., Sohn, J., Jeong, J.-J., Jeon, B.-N., Jang, M., An, C., Lee, S., et al. (2021) · Nature Microbiology · doi:10.1038/s41564-020-00831-6 · Cited by 325

The Human Microbiome and Cancer

Rajagopala, S. V., Vashee, S., Oldfield, L. M., Suzuki, Y., Venter, J. C., Telenti, A., & Nelson, K. E. (2017) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-16-0249 · Cited by 327

Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases

Jiao, Y., Wu, L., Huntington, N. D., & Zhang, X. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00282 · Cited by 321

Soil biota, antimicrobial resistance and planetary health

Zhu, Y., Zhao, Y., Zhu, D., Gillings, M. R., Peñuelas, J., Ok, Y. S., Capon, A. G., & Banwart, S. A. (2019) · Environment International · doi:10.1016/j.envint.2019.105059 · Cited by 317

The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes

Sencio, V., Machado, M. G., & Trottein, F. (2021) · Mucosal Immunology · doi:10.1038/s41385-020-00361-8 · Cited by 322

Gut microbiota injury in allogeneic haematopoietic stem cell transplantation

Shono, Y., & van den Brink, M. R. M. (2018) · Nature reviews. Cancer · doi:10.1038/nrc.2018.10 · Cited by 320

Host Genetics and Gut Microbiome: Challenges and Perspectives

Kurilshikov, A., Wijmenga, C., Fu, J., & Zhernakova, A. (2017) · Trends in Immunology · doi:10.1016/j.it.2017.06.003 · Cited by 309

Bridging intestinal immunity and gut microbiota by metabolites

Wang, G., Huang, S., Wang, Y., Cai, S., Yu, H., Liu, H., Zeng, X., Zhang, G., & Qiao, S. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03190-6 · Cited by 305

Control of Immunity by the Microbiota

Ansaldo, E., Farley, T. K., & Belkaid, Y. (2021) · Annual Review of Immunology · doi:10.1146/annurev-immunol-093019-112348 · Cited by 312

Intestinal epithelial cells: At the interface of the microbiota and mucosal immunity

Soderholm, A. T., & Pedicord, V. A. (2019) · Immunology · doi:10.1111/imm.13117 · Cited by 281

The impacts of natural polysaccharides on intestinal microbiota and immune responses – a review

Tang, C., Ding, R., Sun, J. G., Liu, J., Kan, J., & Jin, C. (2019) · Food & Function · doi:10.1039/c8fo01946k · Cited by 284

A systematic review of the impacts of exposure to micro- and nano-plastics on human tissue accumulation and health

Feng, Y., Tu, C., Li, R., Wu, D., Yang, J., Xia, Y., Peijnenburg, W. J. G. M., & Luo, Y. (2023) · Eco-Environment & Health · doi:10.1016/j.eehl.2023.08.002 · Cited by 290

Effects induced by polyethylene microplastics oral exposure on colon mucin release, inflammation, gut microflora composition and metabolism in mice

Sun, H., Chen, N., Yang, X., Xia, Y., & Wu, D. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.112340 · Cited by 285

Recent insights into uptake, toxicity, and molecular targets of microplastics and nanoplastics relevant to human health impacts

Khan, A., & Jia, Z. (2023) · iScience · doi:10.1016/j.isci.2023.106061 · Cited by 283

Adaptive immune education by gut microbiota antigens

Zhao, Q. S., & Elson, C. O. (2018) · Immunology · doi:10.1111/imm.12896 · Cited by 288

TLR4 regulates RORγt+ regulatory T-cell responses and susceptibility to colon inflammation through interaction with Akkermansia muciniphila

Liu, Y., Yang, M., Tang, L., Wang, F., Huang, S., Liu, S., Lei, Y., Wang, S., Xie, Z., Wang, W., et al. (2022) · Microbiome · doi:10.1186/s40168-022-01296-x · Cited by 273

An Overview of Physical, Microbiological and Immune Barriers of Oral Mucosa

Şenel, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157821 · Cited by 268

Microbiome and Gut Dysbiosis

Belizário, J. E., & Faintuch, J. (2018) · Experientia supplementum · doi:10.1007/978-3-319-74932-7_13 · Cited by 271

Secretory Leukoprotease Inhibitor (Slpi) Expression Is Required for Educating Murine Dendritic Cells Inflammatory Response Following Quercetin Exposure

Santis, S. D., Galleggiante, V., Scandiffio, L., Liso, M., Sommella, E., Sobolewski, A., Spilotro, V., Pinto, A., Campiglia, P., Serino, G., et al. (2017) · Nutrients · doi:10.3390/nu9070706 · Cited by 252

Steering Soil Microbiomes to Suppress Aboveground Insect Pests

Pineda, A., Kaplan, I., & Bezemer, Т. M. (2017) · Trends in Plant Science · doi:10.1016/j.tplants.2017.07.002 · Cited by 258

The contribution of gut bacterial metabolites in the human immune signaling pathway of non-communicable diseases

Hosseinkhani, F., Heinken, A., Thiele, I., Lindenburg, P. W., Harms, A. C., & Hankemeier, T. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1882927 · Cited by 249

An intestinal organ culture system uncovers a role for the nervous system in microbe-immune crosstalk

Yissachar, N., Zhou, Y., Ung, L., Lai, N. Y., Mohan, J. F., Ehrlicher, A., Weitz, D. A., Kasper, D. L., Chiu, I. M., Mathis, D., et al. (2017) · Cell · doi:10.1016/j.cell.2017.02.009 · Cited by 242

Expanded catalog of microbial genes and metagenome-assembled genomes from the pig gut microbiome

Chen, C., Zhou, Y., Fu, H., Xiong, X., Fang, S., Jiang, H., Wu, J., Yang, H., Gao, J., & Huang, L. (2021) · Nature Communications · doi:10.1038/s41467-021-21295-0 · Cited by 249

The human microbiome

Blum, H. E. (2017) · Advances in Medical Sciences · doi:10.1016/j.advms.2017.04.005 · Cited by 246

Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota

Liang, Y., Zhan, J., Liu, D., Luo, M., Han, J., Liu, X., Liu, C., Cheng, Z. Z., Zhou, Z., & Wang, P. (2019) · Microbiome · doi:10.1186/s40168-019-0635-4 · Cited by 248

Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines

Chen, L., Qin, H., Zhao, R., Zhao, X., Lin, L., Chen, Y., Lin, Y., Li, Y., Qin, Y., Li, Y., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abc2816 · Cited by 240

Impact of Fecal Microbiota Transplantation on Obesity and Metabolic Syndrome—A Systematic Review

Zhang, Z., Mocanu, V., Cai, C., Dang, J. T., Slater, L., Deehan, E. C., Walter, J., & Madsen, K. L. (2019) · Nutrients · doi:10.3390/nu11102291 · Cited by 245

Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges

Berry, M. D., Gainetdinov, R. R., Hoener, M. C., & Shahid, M. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.07.002 · Cited by 238

T Cells in Osteoarthritis: Alterations and Beyond

Li, Y., Luo, W., Zhu, S., & Lei, G. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00356 · Cited by 235

The microbiota-immune axis as a central mediator of gut-brain communication

Fung, T. C. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104714 · Cited by 234

Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment

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Tryptophan Metabolism and Gut Microbiota: A Novel Regulatory Axis Integrating the Microbiome, Immunity, and Cancer

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