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Genome editing in induced pluripotent stem cells rescues TAF1 levels in X‐linked dystonia‐parkinsonism

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TGFβ Family Signaling Pathways in Pluripotent and Teratocarcinoma Stem Cells’ Fate Decisions: Balancing Between Self-Renewal, Differentiation, and Cancer

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Promoting Alzheimer’s disease research and therapy with stem cell technology

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In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons

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Human Induced Pluripotent Stem Cell-Derived 3D-Neurospheres Are Suitable for Neurotoxicity Screening

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Challenges in the clinical advancement of cell therapies for Parkinson’s disease

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Treating Parkinson's disease in the 21st century: Can stem cell transplantation compete?

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Stem cells for brain repair in neonatal hypoxia–ischemia

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Dual Small-Molecule Targeting of SMAD Signaling Stimulates Human Induced Pluripotent Stem Cells toward Neural Lineages

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DLK1 Promotes Neurogenesis of Human and Mouse Pluripotent Stem Cell-Derived Neural Progenitors Via Modulating Notch and BMP Signalling

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Glycomic Characterization of Induced Pluripotent Stem Cells Derived from a Patient Suffering from Phosphomannomutase 2 Congenital Disorder of Glycosylation (PMM2-CDG)

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Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons

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Transcriptome Analysis of Small Molecule–Mediated Astrocyte-to-Neuron Reprogramming

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An in vitro stem cell model of human epiblast and yolk sac interaction

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Long-Term Expandable SOX9+ Chondrogenic Ectomesenchymal Cells from Human Pluripotent Stem Cells

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A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations

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The utility of patient specific induced pluripotent stem cells for the modelling of Autistic Spectrum Disorders

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Lessons from the Embryonic Neural Stem Cell Niche for Neural Lineage Differentiation of Pluripotent Stem Cells

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A Multiplex High-Throughput Gene Expression Assay to Simultaneously Detect Disease and Functional Markers in Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium

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A combination of small molecules directly reprograms mouse fibroblasts into neural stem cells

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Efficient generation of region-specific forebrain neurons from human pluripotent stem cells under highly defined condition

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Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation

Close, J., Yao, Z., Levi, B. P., Miller, J. A., Bakken, T. E., Menon, V., Ting, J. T., Wall, A., Krostag, A.-R., Thomsen, E. R., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.02.014 · Cited by 53

Enhancing neural differentiation of induced pluripotent stem cells by conductive graphene/silk fibroin films

Niu, Y., Chen, X., Yao, D., Ge, P., Liu, H., & Fan, Y. (2018) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36486 · Cited by 52

Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cells

Sun, X., Song, J., Huang, H., Chen, H., & Qian, K. X. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-1048-1 · Cited by 57

Functional expression and pharmacological modulation of TRPM3 in human sensory neurons

Vangeel, L., Benoit, M., Miron, Y., Miller, P. E., Clercq, K. D., Chaltin, P., Verfaillie, C. M., Vriens, J., & Voets, T. (2020) · British Journal of Pharmacology · doi:10.1111/bph.14994 · Cited by 51

FGF9 induces functional differentiation to Schwann cells from human adipose derived stem cells

Huang, C.-W., Lu, S.-Y., Huang, T.-C., Huang, B.-M., Sun, H. S., Yang, S., Chuang, J., Hsueh, Y., Wu, Y.-T., & Wu, C. (2020) · Theranostics · doi:10.7150/thno.38553 · Cited by 51

Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing

Niederst, E. D., Reyna, S. M., & Goldstein, L. S. B. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-06-1049 · Cited by 51

Human sensory neurons derived from pluripotent stem cells for disease modelling and personalized medicine

Lampert, A., Bennett, D., McDermott, L., Neureiter, A., Eberhardt, E., Winner, B., & Zenke, M. (2020) · Neurobiology of Pain · doi:10.1016/j.ynpai.2020.100055 · Cited by 53

Applications of Brain Organoids for Infectious Diseases

Fan, W., Christian, K. M., Song, H., & Ming, G. (2021) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.167243 · Cited by 56

Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy

Majd, H., Amin, S., Ghazizadeh, Z., Cesiulis, A., Arroyo, E. J., Lankford, K. L., Majd, A., Farahvashi, S., Chemel, A. K., Okoye, M., et al. (2023) · Cell stem cell · doi:10.1016/j.stem.2023.04.006 · Cited by 54

Decoding transcriptional identity in developing human sensory neurons and organoid modeling

Tian, L., Wang, M., Zhou, W., Ni, Q., Yue, Y., Wang, W., Shi, Y., Liu, Z., Li, C., Hong, B., et al. (2024) · Cell · doi:10.1016/j.cell.2024.10.023 · Cited by 60

Engineering Efficient Retinal Pigment Epithelium Differentiation From Human Pluripotent Stem Cells

Lane, A., Philip, L. R., Ruban, L., Fynes, K., Smart, M. J. K., Carr, A. F., Mason, C., & Coffey, P. J. (2014) · Stem Cells Translational Medicine · doi:10.5966/sctm.2014-0094 · Cited by 51

Targeting LRRK2 in Parkinson’s disease: an update on recent developments

Chan, S. L., & Tan, E. (2017) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2017.1323881 · Cited by 51

Dioxins and related environmental contaminants increase TDP-43 levels

Ash, P. E. A., Stanford, E. A., Abdulatif, A. A., Ramirez‐Cardenas, A., Ballance, H. I., Boudeau, S., Jeh, A., Murithi, J. M., Tripodis, Y., Murphy, G. J., et al. (2017) · Molecular Neurodegeneration · doi:10.1186/s13024-017-0177-9 · Cited by 54

Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality

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Cell Transplantation and Gene Therapy in Parkinson's Disease

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Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines

Kagohara, L. T., Zamunér, F. T., Davis-Marcisak, E. F., Sharma, G., Considine, M., Allen, J., Yegnasubramanian, S., Gaykalova, D. A., & Fertig, E. J. (2020) · British Journal of Cancer · doi:10.1038/s41416-020-0851-5 · Cited by 50

Brain organoids: A revolutionary tool for modeling neurological disorders and development of therapeutics

Acharya, P., Choi, N. Y., Shrestha, S., Jeong, S., & Lee, M. (2023) · Biotechnology and Bioengineering · doi:10.1002/bit.28606 · Cited by 50

Induced pluripotent stem cells as a discovery tool for Alzheimer׳s disease

Sullivan, S. E., & Young-Pearse, T. L. (2017) · Brain Research · doi:10.1016/j.brainres.2015.10.005 · Cited by 50

Therapeutic Application of Stem Cell Technology toward the Treatment of Parkinson’s Disease

Nishimura, K., & TAKAHASHI, J. C. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b12-00929 · Cited by 50

Compounds with species and cell type specific toxicity identified in a 2000 compound drug screen of neural stem cells and rat mixed cortical neurons

Malik, N., Efthymiou, A. G., Mather, K., Chester, N., Wang, X., Nath, A., Rao, M. S., & Steiner, J. P. (2014) · NeuroToxicology · doi:10.1016/j.neuro.2014.10.007 · Cited by 51

Probing disorders of the nervous system using reprogramming approaches

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Human Induced Pluripotent Cell-Derived Sensory Neurons for Fate Commitment of Bone Marrow-Derived Schwann Cells: Implications for Remyelination Therapy

Cai, S., Han, L., Ao, Q., Chan, Y., & Shum, D. K. (2016) · Stem Cells Translational Medicine · doi:10.5966/sctm.2015-0424 · Cited by 50

Human Pluripotent Stem Cell-Derived Neural Crest Cells for Tissue Regeneration and Disease Modeling

Srinivasan, A., & Toh, Y. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00039 · Cited by 50

Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons

Huang, G., Chen, S., Chen, X., Zheng, J., Xu, Z., Torshizi, A. D., Gong, S., Chen, Q., Ma, X., Yu, J., et al. (2019) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2019.00023 · Cited by 58

Gelator Length Precisely Tunes Supramolecular Hydrogel Stiffness and Neuronal Phenotype in 3D Culture

Godbe, J. M., Freeman, R., Burbulla, L. F., Lewis, J. A., Krainc, D., & Stupp, S. I. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.9b01585 · Cited by 51

Grafted human pluripotent stem cell-derived cortical neurons integrate into adult human cortical neural circuitry

Hansen, M. G., Laterza, C., Palma-Tortosa, S., Kvist, G., Monni, E., Tsupykov, O., Tornero, D., Uoshima, N., Soriano, J., Bengzon, J., et al. (2020) · Stem Cells Translational Medicine · doi:10.1002/sctm.20-0134 · Cited by 48

Highly Efficient Neural Conversion of Human Pluripotent Stem Cells in Adherent and Animal-Free Conditions

Lukovic, D., Díez-Lloret, A., Stojković, P., Rodríguez–Martínez, D., Aragó, M. A. P., Rodríguez-Jiménez, F. J., González‐Rodríguez, P., López‐Barneo, J., Syková, E., Jendelová, P., et al. (2017) · Stem Cells Translational Medicine · doi:10.1002/sctm.16-0371 · Cited by 38

Conversion of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells into neural cells

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Dual Small-Molecule Targeting of SMAD Signaling Stimulates Human Induced Pluripotent Stem Cells toward Neural Lineages

Wattanapanitch, M., Klincumhom, N., Potirat, P., Amornpisutt, R., Lorthongpanich, C., U‐pratya, Y., Laowtammathron, C., Kheolamai, P., Poungvarin, N., & Issaragrisil, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106952 · Cited by 53

Neural induction - Dual SMAD inhibition

Tomishima, M. J. (2014) · StemBook · doi:10.3824/stembook.1.57.1 · Cited by 11

Robust induction of nigro-striatal neurons from human induced pluripotent stem cells by small compound-based signal controlling

Nishimura, K., Amimoto, N., Kato, T., Hirao, M., & Takata, K. (2021) · Proceedings for Annual Meeting of The Japanese Pharmacological Society · doi:10.1254/jpssuppl.94.0_1-p1-23