In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

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Items 301–400 of 771

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11. Emerging Approaches for Spatiotemporal Control of Targeted Genome with Inducible CRISPR-Cas9
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14. Development of a CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain
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18. Efficient in vivo neuronal genome editing in the mouse brain using nanocapsules containing CRISPR-Cas9 ribonucleoproteins
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20. Comparison of CRISPR/Cas Endonucleases for in vivo Retinal Gene Editing
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21. Gene Editing: A New Tool for Viral Disease
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22. CRISPR applications in ophthalmologic genome surgery
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23. Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration
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24. Applications of CRISPR/Cas9 in the Mammalian Central Nervous System.
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28. CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling
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29. A non-inheritable maternal Cas9-based multiple-gene editing system in mice
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30. The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and Survival of Cells
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31. Genome and base editing for genetic hearing loss
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32. Seasonal regulation of behaviour: what role do hormone receptors play?
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33. On the functional relevance of spatiotemporally-specific patterns of experience-dependent long noncoding RNA expression in the brain
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34. Techniques for investigating lncRNA transcript functions in neurodevelopment
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35. Genome-wide distribution of linker histone H1.0 is independent of MeCP2
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36. The Processes of Anterior Pituitary Hormone Pulse Generation
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37. Somatic mutations in disorders with disrupted brain connectivity
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38. In Vivo Applications of CRISPR-Based Genome Editing in the Retina
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39. CRISPR therapy towards an HIV cure
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40. A Comprehensive Review of Recent Advancements in Cancer Immunotherapy and Generation of CAR T Cell by CRISPR-Cas9
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41. Dopaminergic dysfunction in neurodevelopmental disorders: recent advances and synergistic technologies to aid basic research
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42. Oxytocin, vasopressin and social behavior in the age of genome editing: a comparative perspective
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43. Advanced In vivo Use of CRISPR/Cas9 and Anti-sense DNA Inhibition for Gene Manipulation in the Brain
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44. Genome Engineering with TALE and CRISPR Systems in Neuroscience
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45. Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission
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46. LIM and SH3 protein 1 induces glioma growth and invasion through PI3K/AKT signaling and epithelial-mesenchymal transition
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47. Antisense Oligonucleotide- and CRISPR-Cas9-Mediated Rescue of mRNA Splicing for a Deep Intronic CLRN1 Mutation
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48. Harnessing the evolving CRISPR/Cas9 for precision oncology
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49. CRISPR/Cas9-Based therapeutics as a promising strategy for management of Alzheimer’s disease: progress and prospects
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50. Neural Circuits Underlying Rodent Sociality: A Comparative Approach
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51. CRISPR-Mediated Modification of DNA Methylation Pattern in the New Era of cancer therapy
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53. Efficient CRISPR-rAAV engineering of endogenous genes to study protein function by allele-specific RNAi
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56. The Quantitative and Molecular Genetics of Individual Differences in Animal Personality
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57. Genome Editing in a Wide Area of the Brain Using Dendrimer-Based Ternary Polyplexes of Cas9 Ribonucleoprotein
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58. Neuroepigenetic Editing
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59. Therapeutic genome engineering via CRISPR ‐Cas systems
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60. Adeno‐Associated Viral Vectors for Homology‐Directed Generation of CAR‐T Cells
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61. Innovative Precision Gene‐Editing Tools in Personalized Cancer Medicine
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62. Development of a Self-Restricting CRISPR-Cas9 System to Reduce Off-Target Effects
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63. Combined lentiviral- and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells
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64. Genetically Encoded Double-Stranded DNA-Based Nanostructure Folded by a Covalently Bivalent CRISPR/dCas System
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65. Targeted DNA Demethylation: Vectors, Effectors and Perspectives
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66. Combining CRISPR/Cas9 and rAAV Templates for Efficient Gene Editing
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67. Neuro-Immuno-Gene- and Genome-Editing-Therapy for Alzheimer’s Disease: Are We There Yet?
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68. Magnetic Nanoparticle‐Assisted Non‐Viral CRISPR‐Cas9 for Enhanced Genome Editing to Treat Rett Syndrome
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71. Therapeutic applications of CRISPR RNA-guided genome editing
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72. Applications of CRISPR/Cas9 for Gene Editing in Hereditary Movement Disorders
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73. CASAAV: A CRISPR‐Based Platform for Rapid Dissection of Gene Function In Vivo
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74. Delivery methods for site-specific nucleases: Achieving the full potential of therapeutic gene editing
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75. CRISPR/Cas9-Mediated Genome Editing for Huntington’s Disease
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76. Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina
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77. CRISPR Tools for Physiology and Cell State Changes: Potential of Transcriptional Engineering and Epigenome Editing
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78. CRISPR knockdown of Kcnq3 attenuates the M-current and increases excitability of NPY/AgRP neurons to alter energy balance
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79. CRISPR base editing of cis-regulatory elements enables the perturbation of neurodegeneration-linked genes
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81. Genome editing in the mammalian brain using the CRISPR–Cas system
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86. Genome Editing in Neurosciences
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88. Adeno-associated virus-mediated delivery of CRISPR-Cas9 for genome editing in the central nervous system
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92. Methodologies and Challenges for CRISPR/Cas9 Mediated Genome Editing of the Mammalian Brain
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93. Revisiting gene delivery to the brain: silencing and editing
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94. Overview of CRISPR–Cas9 Biology
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96. Genome and Epigenome Editing in Mechanistic Studies of Human Aging and Aging-Related Disease
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