Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors

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RNA-Guided Human Genome Engineering via Cas9

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DNA targeting specificity of RNA-guided Cas9 nucleases

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

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High-Frequency off-Target Mutagenesis Induced by CRISPR-Cas Nucleases in Human Cells

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

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Efficient Immune Cell Genome Engineering with Improved CRISPR Editing ToolsPreprint

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Target-matched increased fidelity SpCas9 variants can edit any target without genome-wide off-target effectsPreprint

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Reduced Binding Activity of Vaccine Serum to Omicron Receptor-Binding DomainPreprint

Wang, T., Weng, S., Li, M., Wang, Q., Yang, Z., Wang, X., Yin, Y., Zhou, Q., Lirong, Z., Tao, F., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4074674 · Cited by 1

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Nguyen, H. N. (2015)

Engineering pentatricopeptide repeat proteins for programmable nucleic acid manipulation

Chia, T. S. (2016) · UWA Profiles and Research Repository (University of Western Australia)

Genome-wide Massive Sequencing in Embryonic Stem Cell Biology:Recent Insights and Challenges

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A systemically-delivered stem cell therapy for dry age related macular degeneration

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Generation of knockout human iPSCs to investigate genes associated with telomere length

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Article Watch: July 2015

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Development of Novel CRISPR-Based Methods for Transcriptional Control Over Bacterial Gene Expression

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Generation of Defined Genomic Modifications Using CRISPR-CAS9 in Human Pluripotent Stem Cells

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Pharmacodynamic Evaluation: Gene Therapy

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CRISPR-CAS9 fighting human immunodeficiency virus HIV-1 subtype in CD4+ T lymphocytes: a literature review / CRISPR-CAS9 e combate ao vírus da imunodeficiência humana subtipo HIV-1 em LINFÓCITOS T CD4+: uma revisão de literatura

dos Anjos, I. W. T., Filho, I. A. D. A., Marinho, L. V. B. V., Santos, N. V. D. M., & Cézar, N. J. B. (2020) · Brazilian Journal of Health Review · doi:10.34119/bjhrv3n5-114 · Cited by 2

CRISPR, ZFNS, and TALENS for Hemoglobinopathies an Analysis

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Extension and Improvement of CRISPR-Based Technology

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Crispr-Embedding: CRISPR/Cas9 Off-Target Activity Prediction Using DNA k-Mer EmbeddingPreprint

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Faculty Opinions recommendation of DeepCRISPR: optimized CRISPR guide RNA design by deep learning.

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Pharmacodynamic Evaluation: Gene Therapy

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Molecular Mechanisms of Type II CRISPR ‐ Cas Systems

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Development of new increased fidelity SpCas9 variants

Kulcsár, P. I. (2019) · SZTE Repository of Dissertations (University of Szeged) · doi:10.14232/phd.10317

Weighted Off-target and Efficiency Scoring Reveal Genome Composition-Dependent Optimal CRISPR/Cas9 Guide DesignPreprint

Krishna, Y. K. Y. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.13.670047

CRISPR System and AI Applications

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Additional file 4 of Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches

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Additional file 2 of ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing

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Additional file 1 of ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing

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Additional file 3 of ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing

Breton, C. A., Clark, P., Wang, L., Greig, J. A., & Wilson, J. M. (2020) · Figshare · doi:10.6084/m9.figshare.11999373

Additional file 1 of Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches

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Additional file 6 of Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches

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Additional file 3 of Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches

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Nanocarriers for the delivery of the CRISPR/Cas9 system

Hwang, S., Ko, H., Lee, H.-Y., & Choi, J. H. (2025) · Nanomedicine · doi:10.1080/17435889.2025.2598332 · Cited by 1

3-D Genome organization of DNA damage repair

Banerjee, U. K. (2017) · theses.fr (ABES) · doi:10.70675/25480b49zc194z4a4bzb6b0z2f84dab6ccef

A genetic dissection of human ILC development and plasticity

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Ex vivo gene therapy for β-hemoglobinpathies and metabolic disorders

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Platinum TALEN-mediated nonviral gene editing facilitates clinical-scale production of cancer antigen-reactive T cells

Toishigawa, K., Magoori, K., Sato, H., Edahiro, T., Ureshino, H., Shindo, T., Suzuki, R., Sakuma, T., Yamamoto, T., Okada, M., et al. (2026) · Cytotherapy · doi:10.1016/j.jcyt.2026.102911

An interpretable deep learning framework uncovers features governing CRISPR-Cas9 genome-editing efficiency

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Detection of CRISPR/Cas9-Generated off-target effect by integration-defective lentiviral vector

Wang, X., Wu, Y., & Yee, J.-K. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-0687-2_14 · Cited by 5

CRISPR off-target detection

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Unbiased Detection of Off-target Cleavage by CRISPR/Cas9 and TALENs Using Integration-defective Lentiviral Vectors

Wu, Y., & Yee, J. (2018) · Cambridge University Press eBooks · doi:10.1017/9781316756300.004

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SpacerScope: Binary-vectorized, genome-wide off-target profiling for RNA-guided nucleases without prior candidate-site biasPreprint

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