Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Integrative genomics viewer

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RNA-Guided Human Genome Engineering via Cas9

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

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CRISPR-Cas systems for editing, regulating and targeting genomes

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Genetic screens in human cells using the CRISPR-Cas9 system

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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

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RNA-guided genetic silencing systems in bacteria and archaea

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One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

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Double-strand break repair: 53BP1 comes into focus

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Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

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Therapeutic genome engineering via CRISPR ‐Cas systems

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A CRISPR /LbCas12a‐based method for highly efficient multiplex gene editing in Physcomitrella patens

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Sequential i-GONAD: An Improved In Vivo Technique for CRISPR/Cas9-Based Genetic Manipulations in Mice

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Gene editing in dermatology: Harnessing CRISPR for the treatment of cutaneous disease

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Multiplexed tat-Targeting CRISPR-Cas9 Protects T Cells from Acute HIV-1 Infection with Inhibition of Viral Escape

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A Cas9–transcription factor fusion protein enhances homology-directed repair efficiency

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Gene Therapy for Neurodegenerative Disease: Clinical Potential and Directions

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Approaches to Enhance Precise CRISPR/Cas9-Mediated Genome Editing

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Recent Advances in CRISPR/Cas9-Based Genome Editing Tools for Cardiac Diseases

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Gene editing innovations and their applications in cardiomyopathy research

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Combining CRISPR/Cas9 and rAAV Templates for Efficient Gene Editing

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A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases

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CRISPR editing in biological and biomedical investigation

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Delivery methods for site-specific nucleases: Achieving the full potential of therapeutic gene editing

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One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation

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Targeted gene knockin in zebrafish using the 28S rDNA-specific non-LTR-retrotransposon R2Ol

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Functional Genomics in Pancreatic β Cells: Recent Advances in Gene Deletion and Genome Editing Technologies for Diabetes Research

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Persistence of CRISPR/Cas9 Gene Edited Hematopoietic Stem Cells Following Transplantation: A Systematic Review and Meta-Analysis of Preclinical Studies

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CRISPR-Based Genome Editing as a New Therapeutic Tool in Retinal Diseases

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Recombinant Adeno-Associated Virus-Mediated Editing of the G551D Cystic Fibrosis Transmembrane Conductance Regulator Mutation in Ferret Airway Basal Cells

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Perspectives of gene editing for cattle farming in tropical and subtropical regions

Camargo, L. S. A., Saraiva, N. Z., Oliveira, C. S., Carmickle, A. T., de Lemos, D. R., Siqueira, L. G. B., & Denicol, A. C. (2022) · Animal Reproduction · doi:10.1590/1984-3143-ar2022-0108 · Cited by 28

Accelerated genome engineering through multiplexing

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T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system

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Genome editing in the mammalian brain using the CRISPR–Cas system

Nishiyama, J. (2018) · Neuroscience Research · doi:10.1016/j.neures.2018.07.003 · Cited by 25

Harnessing CRISPR/Cas9 technology in cardiovascular disease

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Single-cell quantification of the concentrations and dissociation constants of endogenous proteins

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CRISPR/Cas9: A new tool for the study and control of helminth parasites

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TALENs-Assisted Multiplex Editing for Accelerated Genome Evolution To Improve Yeast Phenotypes

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In vivo gene therapy potentials of CRISPR-Cas9

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Overview of CRISPR–Cas9 BiologyPreprint

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In Vivo Genome Editing in Type I and II Methanotrophs Using a CRISPR/Cas9 System

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Progress and Prospects of Gene Editing in Pluripotent Stem Cells

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The Therapeutic Potential of CRISPR/Cas9 Systems in Oncogene-Addicted Cancer Types: Virally Driven Cancers as a Model System

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CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells

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The Application of CRISPR/Cas9 for the Treatment of Retinal Diseases.

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Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering

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CRISPR/Cas9 technology: towards a new generation of improved CAR-T cells for anticancer therapies

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Chlamydomonas POLQ is necessary for CRISPR/Cas9-mediated gene targeting

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THE JOURNEY OF CRISPR-CAS9 FROM BACTERIAL DEFENSE MECHANISM TO A GENE EDITING TOOL IN BOTH ANIMALS AND PLANTS

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CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish

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Applications of the CRISPR-Cas9 system in kidney research

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CRISPR-mediated knock-in in the mouse embryo using long single stranded DNA donors synthesised by biotinylated PCR

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Leptin gene-targeted editing in ob/ob mouse adipose tissue based on the CRISPR/Cas9 system

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From DNA break repair pathways to CRISPR/Cas-mediated gene knock-in methods

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Generation of genetically modified mice using CRISPR/Cas9 and haploid embryonic stem cell systems.

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Genome and Epigenome Editing in Mechanistic Studies of Human Aging and Aging-Related Disease

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Extraembryonic Endoderm (XEN) Cells Capable of Contributing to Embryonic Chimeras Established from Pig Embryos

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Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9

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Genetically engineered birds; pre-CRISPR and CRISPR era

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Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface

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CRISPR‐Cas‐Assisted Multiplexing (CAM): Simple Same‐Day Multi‐Locus Engineering in Yeast

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CRISPR-Cas9 mediated genetic engineering for the purification of the endogenous integrator complex from mammalian cells

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Application of Genome Editing Techniques in Immunology

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Plant DNA Repair Pathways and Their Applications in Genome Engineering

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Pleiotropic roles of tankyrase/PARP proteins in the establishment and maintenance of human naïve pluripotency

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Efficient correction of a deleterious point mutation in primary horse fibroblasts with CRISPR-Cas9

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Advances and challenges in genetic technologies to produce single-sex litters

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Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency

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CRISPR/Cas gene editing in the human germline

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Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice

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Erratum: Corrigendum: Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Maruyama, T., Dougan, S. K., Truttmann, M. C., Bilate, A. M. B., Ingram, J. R., & Ploegh, H. L. (2016) · Nature Biotechnology · doi:10.1038/nbt0216-210c · Cited by 21

AAV vector-derived elements integrate into Cas9-generated double-strand breaks and disrupt gene transcription

Bazick, H., Mao, H., Niehaus, J. K., Wolter, J. M., & Zylka, M. J. (2024) · Molecular Therapy · doi:10.1016/j.ymthe.2024.09.032 · Cited by 20

Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations

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Baculovirus-based genome editing in primary cells

Mansouri, M., Ehsaei, Z., Taylor, V., & Berger, P. (2017) · Plasmid · doi:10.1016/j.plasmid.2017.01.003 · Cited by 20

Use of CRISPR/Cas9 to model brain diseases

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AIRE is a critical spindle-associated protein in embryonic stem cells

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A Versatile Tool for the Quantification of CRISPR/Cas9-Induced Genome Editing Events in Human Hematopoietic Cell Lines and Hematopoietic Stem/Progenitor Cells

Jayavaradhan, R., Pillis, D. M., & Malik, P. (2018) · Journal of Molecular Biology · doi:10.1016/j.jmb.2018.05.005 · Cited by 20

Overcoming the Undesirable CRISPR-Cas9 Expression in Gene Correction

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Practical considerations on performing and analyzing CLIP-seq experiments to identify transcriptomic-wide RNA-protein interactions

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Gene Editing in Clinical Practice: Where are We?

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A robust CRISPR–Cas9-based fluorescent reporter assay for the detection and quantification of DNA double-strand break repair

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RNA activation of haploinsufficient Foxg1 gene in murine neocortex

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Gene editing and CRISPR-dependent homology-mediated end joining

Ruis, B. L., Bielinsky, A., & Hendrickson, E. A. (2025) · Experimental & Molecular Medicine · doi:10.1038/s12276-025-01442-z · Cited by 20

Making gene editing a therapeutic reality

Conboy, I. M., Murthy, N., Etienne, J., & Robinson, Z. R. (2018) · F1000Research · doi:10.12688/f1000research.16106.1 · Cited by 19

Deletion of mFICD AMPylase alters cytokine secretion and affects visual short-term learning in vivo

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An improved medium formulation for efficient ex vivo gene editing, expansion and engraftment of hematopoietic stem and progenitor cells

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Enhanced Biosynthesis Performance of Heterologous Proteins in CHO-K1 Cells Using CRISPR-Cas9

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CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing

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NHEJ inhibitor SCR7 and its different forms: Promising CRISPR tools for genome engineering

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Rapid genome editing by CRISPR-Cas9-POLD3 fusion

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Next-generation mammalian genetics toward organism-level systems biology

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CRISPR/Cas: An intriguing genomic editing tool with prospects in treating neurodegenerative diseases

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Focused ultrasound and microbubble-mediated delivery of CRISPR-Cas9 ribonucleoprotein to human induced pluripotent stem cells

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CRISPR/Cas9 as a Mutagenic Factor

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Next-generation CRISPR technology for genome, epigenome and mitochondrial editing

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Interspecies chimeric complementation for the generation of functional human tissues and organs in large animal hosts

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To Crispr And Beyond: The Evolution Of Genome Editing In Stem Cells

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Modeling Cancer in the CRISPR Era

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