Cited by 243Genetically Modified Organisms ResearchAgricultural safety and regulationsCRISPR and Genetic Engineering

The DOI matches its Crossref record; 65 of the 67 references it cites were found in a registry or an index.

Regulating transgenic crops sensibly: lessons from plant breeding, biotechnology and genomics

Bradford, Kent J, Van Deynze, Allen, Gutterson, Neal, Parrott, Wayne, Strauss, Steven H·2005·Nature Biotechnology

Open this paper in CoChat — free account

Abstract

The costs of meeting regulatory requirements and market restrictions guided by regulatory criteria are substantial impediments to the commercialization of transgenic crops. Although a cautious approach may have been prudent initially, we argue that some regulatory requirements can now be modified to reduce costs and uncertainty without compromising safety. Long-accepted plant breeding methods for incorporating new diversity into crop varieties, experience from two decades of research on and commercialization of transgenic crops, and expanding knowledge of plant genome structure and dynamics all indicate that if a gene or trait is safe, the genetic engineering process itself presents little potential for unexpected consequences that would not be identified or eliminated in the variety development process before commercialization. We propose that as in conventional breeding, regulatory emphasis should be on phenotypic rather than genomic characteristics once a gene or trait has been shown to be safe.

Integrity signals

Registry

Crossref · 10.1038/nbt1084

Cites

65 of 65 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana
Alonso, J. M., Stepanova, A. N., Leisse, T. J., Kim, C. J., Chen, H., Shinn, P., Stevenson, D. K., Zimmerman, J., Barajas, P., Cheuk, R., et al. (2003) · Science · doi:10.1126/science.1086391 · Cited by 5,105
Nuclear DNA content of some important plant species
Arumuganathan, K., & Earle, E. D. (1991) · Plant Molecular Biology Reporter · doi:10.1007/bf02672069 · Cited by 3,237
Role of MicroRNAs in Plant and Animal Development
Carrington, J. C., & Ambros, V. (2003) · Science · doi:10.1126/science.1085242 · Cited by 1,772
Nested Retrotransposons in the Intergenic Regions of the Maize Genome
SanMiguel, P. J., Tikhonov, A. P., Jin, Y., Motchoulskaia, N., Zakharov, D., Melake‐Berhan, A., Springer, P. S., Edwards, K. J., Lee, M., AVRAMOVA, Z. V., et al. (1996) · Science · doi:10.1126/science.274.5288.765 · Cited by 1,402
Allopolyploidy-Induced Rapid Genome Evolution in the Wheat (Aegilops-Triticum) Group
Özkan, H., Levy, A. A., & Feldman, M. (2001) · The Plant Cell · doi:10.1105/tpc.010082 · Cited by 656
CONTROL OF PAPAYA RINGSPOT VIRUS IN PAPAYA: A Case Study
Gonsalves, D. (1998) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.36.1.415 · Cited by 593
The Genetic, Developmental, and Molecular Bases of Fruit Size and Shape Variation in Tomato
Tanksley, S. D. (2004) · The Plant Cell · doi:10.1105/tpc.018119 · Cited by 586
Assessment of the food safety issues related to genetically modified foods
Kuiper, H. A., Kleter, G. A., Noteborn, H. P. J. M., & Kok, E. J. (2001) · The Plant Journal · doi:10.1046/j.1365-313x.2001.01119.x · Cited by 557
SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines
Ching, A., Caldwell, K. S., Jung, M., Dolan, M., Smith, O. S., Tingey, S. V., Morgante, M., & Rafalski, A. J. (2002) · BMC Genetics · doi:10.1186/1471-2156-3-19 · Cited by 483
Intraspecific violation of genetic colinearity and its implications in maize
Fu, H., & Dooner, H. K. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.132259199 · Cited by 474

Flagged first, then by citations

Show all 67 references

2 of the 67 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

Pew Initiative on Food and Biotechnology. Impacts of Biotech Regulation on Small Business and University Research: Possible Barriers and Potential Solutions (Washington, DC, 2004). http://pewagbiotech.org/events/0602/proceedings.pdf .
Kalaitzandonakes, N. Strategies and structure in the emerging global seed industry. Biofutur 215, 38–42 (2001).
Jaffe, G. Withering on the Vine: Will Agricultural Biotech's Promises Bear Fruit? (Center for Science in the Public Interest, Washington, DC, 2005). http://cspinet.org/new/pdf/withering_on_the_vine.pdf .
National Research Council. Field-Testing Genetically Modified Organisms: Framework for Decision (National Academy Press, Washington, DC, 1989).

Sorted by citations

Transgenic crops expressing Bacillus thuringiensis toxins and biological control
Romeis, J., Meissle, M., & Bigler, F. (2006) · Nature Biotechnology · doi:10.1038/nbt1180 · Cited by 719
Assessment of risk of insect-resistant transgenic crops to nontarget arthropods
Romeis, J., Bartsch, D. K., Bigler, F., Candolfi, M. P., Gielkens, M. M. C., Hartley, S. E., Hellmich, R. L., Huesing, J. E., JEPSON, P. C., Layton, R. J., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt1381 · Cited by 505
The economics of genetically modified crops
Qaim, M. (2009) · Annual Review of Resource Economics · doi:10.1146/annurev.resource.050708.144203 · Cited by 465
Cisgenic plants are similar to traditionally bred plants
Schouten, H. J., Krens, F. A., & Jacobsen, E. (2006) · EMBO Reports · doi:10.1038/sj.embor.7400769 · Cited by 397
Deployment of new biotechnologies in plant breeding
Lusser, M., Parisi, C., Plan, D., & Rodríguez-Cerezo, E. (2012) · Nature Biotechnology · doi:10.1038/nbt.2142 · Cited by 342
Advanced genetic tools for plant biotechnology
Liu, W., Yuan, J. S., & Stewart, C. N. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3583 · Cited by 239
Compliance costs for regulatory approval of new biotech crops
Kalaitzandonakes, N., Alston, J. M., & Bradford, K. J. (2007) · Nature Biotechnology · doi:10.1038/nbt0507-509 · Cited by 199
Self-citation
Genetically modified plants and human health
Key, S., Ma, J. K.-C., & Drake, P. M. (2008) · Journal of the Royal Society of Medicine · doi:10.1258/jrsm.2008.070372 · Cited by 197
Genetically Engineered Plants and Foods: A Scientist's Analysis of the Issues (Part II)
Lemaux, P. G. (2009) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.043008.092013 · Cited by 193
Plant breeding for harmony between agriculture and the environment
Brummer, E. C., Barber, W. T., Collier, S. M., Cox, T. S., Johnson, R. L., Murray, S. C., Olsen, R. T., Pratt, R. C., & Thro, A. M. (2011) · Frontiers in Ecology and the Environment · doi:10.1890/100225 · Cited by 174
Agriculture in the developing world: Connecting innovations in plant research to downstream applications
Delmer, D. P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505895102 · Cited by 169
Unintended compositional changes in genetically modified (GM) crops: 20 years of research
Herman, R. A., & Price, W. D. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf400135r · Cited by 156
Prevalence and impacts of genetically engineered feedstuffs on livestock populations1
Van Eenennaam, A. L., & Young, A. E. (2014) · Journal of Animal Science · doi:10.2527/jas.2014-8124 · Cited by 154
Biotechnology in Agriculture
Herdt, R. W. (2006) · Annual Review of Environment and Resources · doi:10.1146/annurev.energy.31.031405.091314 · Cited by 151
Crop biotechnology and the future of food
Steinwand, M. A., & Ronald, P. C. (2020) · Nature Food · doi:10.1038/s43016-020-0072-3 · Cited by 146
Modern Biotechnology as an Integral Supplement to Conventional Plant Breeding: The Prospects and Challenges
Jauhar, P. P. (2006) · Crop Science · doi:10.2135/cropsci2005.07-0223 · Cited by 143
The function of UDP-glycosyltransferases in plants and their possible use in crop protection
Gharabli, H., Gala, V. D., & Welner, D. H. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108182 · Cited by 133
Genetic modification in floriculture
Chandler, S., & Brugliera, F. (2010) · Biotechnology Letters · doi:10.1007/s10529-010-0424-4 · Cited by 127
Genetically modified crops: success, safety assessment, and public concern
Singh, O. V., Ghai, S., Paul, D., & Jain, R. K. (2006) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0449-8 · Cited by 120
Genetic containment of forest plantations
Brunner, A. M., Li, J., DiFazio, S. P., Shevchenko, O., Montgomery, B. E., Mohamed, R., Wei, H., Ma, C., Elias, A. A., VanWormer, K., et al. (2007) · Tree Genetics & Genomes · doi:10.1007/s11295-006-0067-8 · Cited by 114
Self-citation
Do You See What I See? Examining the Epistemic Barriers to Sustainable Agriculture*
Carolan, M. (2006) · Rural Sociology · doi:10.1526/003601106777789756 · Cited by 121
Defined tetra-allelic gene disruption of the 4-coumarate:coenzyme A ligase 1 (Pv4CL1) gene by CRISPR/Cas9 in switchgrass results in lignin reduction and improved sugar release
Park, J., Yoo, C. G., Flanagan, A., Pu, Y., Debnath, S., Ge, Y., Ragauskas, A. J., & Wang, Z. (2017) · Biotechnology for Biofuels · doi:10.1186/s13068-017-0972-0 · Cited by 112
Genetic engineering of wheat – current challenges and opportunities
Bhalla, P. L. (2006) · Trends in biotechnology · doi:10.1016/j.tibtech.2006.04.008 · Cited by 109
Sustainability of the Sugar Beet Crop
Stevanato, P., Chiodi, C., Broccanello, C., Concheri, G., Biancardi, E., Pavli, O. I., & Skaracis, G. N. (2019) · Sugar Tech · doi:10.1007/s12355-019-00734-9 · Cited by 107
Status and market potential of transgenic biofortified crops
Steur, H. D., Blancquaert, D., Strobbe, S., Lambert, W. E., Gellynck, X., & Straeten, D. V. D. (2015) · Nature Biotechnology · doi:10.1038/nbt.3110 · Cited by 106
Recent advances in genetic transformation of forage and turf grasses
Wang, Z., & Ge, Y. (2006) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1079/ivp2005726 · Cited by 105
Application of food and feed safety assessment principles to evaluate transgenic approaches to gene modulation in crops
Parrott, W. A., Chassy, B. M., Ligon, J., Meyer, L. S., Petrick, J. S., Zhou, J., Herman, R. A., Delaney, B., & Levine, M. J. (2010) · Food and Chemical Toxicology · doi:10.1016/j.fct.2010.04.017 · Cited by 102
Self-citation
Trends in Approval Times for Genetically Engineered Crops in the United States and the European Union
Smart, R. D., Blum, M., & Wesseler, J. (2016) · Journal of Agricultural Economics · doi:10.1111/1477-9552.12171 · Cited by 102
Ethics in the Societal Debate on Genetically Modified Organisms: A (Re)Quest for Sense and Sensibility
Devos, Y., Maeseele, P. A., Reheul, D., Speybroeck, L. V., & Waele, D. D. (2007) · Journal of Agricultural and Environmental Ethics · doi:10.1007/s10806-007-9057-6 · Cited by 100
Genomic and phenotypic analyses of six offspring of a genome-edited hornless bull
Young, A. E., Mansour, T. A., McNabb, B. R., Owen, J. R., Trott, J. F., Brown, C. T., & Eenennaam, A. L. V. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0266-0 · Cited by 100
Lessons from the ‘Humanitarian Golden Rice’ project: regulation prevents development of public good genetically engineered crop products
Potrykus, I. (2010) · New Biotechnology · doi:10.1016/j.nbt.2010.07.012 · Cited by 93
Integrated weed management systems with herbicide-tolerant crops in the European Union: lessons learnt from home and abroad
Lamichhane, J. R., Devos, Y., Beckie, H. J., Owen, M. D. K., Tillie, P., Messéan, A., & Kudsk, P. (2016) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2016.1180588 · Cited by 93
Natural variation in crop composition and the impact of transgenesis
Harrigan, G. G., Lundry, D. R., Drury, S., Berman, K., Riordan, S. G., Nemeth, M. A., Ridley, W. P., & Glenn, K. C. (2010) · Nature Biotechnology · doi:10.1038/nbt0510-402 · Cited by 89
Genetically modified crops for the bioeconomy: meeting public and regulatory expectations
Chapotin, S. M., & Wolt, J. D. (2007) · Transgenic Research · doi:10.1007/s11248-007-9122-y · Cited by 85
Is genetic engineering ever going to take off in forage, turf and bioenergy crop breeding?
Wang, Z., & Brummer, E. C. (2012) · Annals of Botany · doi:10.1093/aob/mcs027 · Cited by 83
Genetic Modification in Floriculture
Chandler, S., & Tanaka, Y. (2007) · Critical Reviews in Plant Sciences · doi:10.1080/07352680701429381 · Cited by 82
Applications of Protein Engineering and Directed Evolution in Plant Research
Engqvist, M. K. M., & Rabe, K. S. (2019) · PLANT PHYSIOLOGY · doi:10.1104/pp.18.01534 · Cited by 81
Food safety risks and consumer health
Chassy, B. M. (2010) · New Biotechnology · doi:10.1016/j.nbt.2010.05.018 · Cited by 80
Ectopic expression of a recessive resistance gene generates dominant potyvirus resistance in plants
Kang, B., Yeam, I., Li, J., Perez, K. W., & Jahn, M. (2007) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2007.00262.x · Cited by 79
Monitoring the presence and expression of transgenes in living plants
Stewart, C. N. (2005) · Trends in Plant Science · doi:10.1016/j.tplants.2005.06.003 · Cited by 79
Evaluating genetic containment strategies for transgenic plants
Lee, D., & Natesan, E. (2006) · Trends in biotechnology · doi:10.1016/j.tibtech.2006.01.006 · Cited by 78
Application of biotechnological tools to Quercus improvement
Viéitez, A. M., Corredoira, E., Martínez, M. T., José, M. C. S., Sánchez, C., Valladares, S., Vidal, N., & Ballester, A. (2011) · European Journal of Forest Research · doi:10.1007/s10342-011-0526-0 · Cited by 77
A critical assessment of regulatory triggers for products of biotechnology: Product vs. process
McHughen, A. (2016) · GM crops & food · doi:10.1080/21645698.2016.1228516 · Cited by 76
Cisgenesis and Intragenesis: New tools For Improving Crops
Espinoza, C., Schlechter, R. O., Herrera, D. P., Torres, E. P., Serrano, A., Medina, C., & Arce‐Johnson, P. (2013) · Biological Research · doi:10.4067/s0716-97602013000400003 · Cited by 74
Estimating the cost of regulating genome edited crops: expert judgment and overconfidence
Lassoued, R., Phillips, P. W. B., Smyth, S. J., & Hesseln, H. (2019) · GM crops & food · doi:10.1080/21645698.2019.1612689 · Cited by 71
Cisgenics - A Sustainable Approach for Crop Improvement
Telem, R. S., Wani, S. H., Singh, N. B., Nandini, R., Sadhukhan, R., Bhattacharya, S., & Mandal, N. (2013) · Current Genomics · doi:10.2174/13892029113146660013 · Cited by 71
Metabolomics, metabolic diversity and genetic variation in crops
Harrigan, G. G., Martino‐Catt, S. J., & Glenn, K. C. (2007) · Metabolomics · doi:10.1007/s11306-007-0076-0 · Cited by 71
Front Matter
Chassy, B. M., Hlywka, J. J., Kleter, G. A., Kok, E. J., Kuiper, H. A., McGloughlin, M. N., Munro, I. C., Phipps, R. H., Reid, J. E., Stein, J., et al. (2008) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/j.1541-4337.2007.00029_1.x · Cited by 70
Genetically engineered trees: Paralysis from good intentions
Strauss, S. H., Costanza, A., & Séguin, A. (2015) · Science · doi:10.1126/science.aab0493 · Cited by 69
Self-citation
A risk-based approach to the regulation of genetically engineered organisms
Conko, G., Kershen, D. L., Miller, H. I., & Parrott, W. A. (2016) · Nature Biotechnology · doi:10.1038/nbt.3568 · Cited by 68
Self-citation
Revisions to USDA biotechnology regulations: The SECURE rule
Hoffman, N. E. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2004841118 · Cited by 67
Natural variation explains most transcriptomic changes among maize plants of MON810 and comparable non-GM varieties subjected to two N-fertilization farming practices
Coll, A., Nadal, A., Collado, R., Capellades, G., Kubista, M., Messeguer, J., & Pla, M. (2010) · Plant Molecular Biology · doi:10.1007/s11103-010-9624-5 · Cited by 68
Genetically engineered crops that fly under the US regulatory radar
Camacho, A. B., Deynze, A. V., Chi‐Ham, C. L., & Bennett, A. B. (2014) · Nature Biotechnology · doi:10.1038/nbt.3057 · Cited by 63
Biotechnology and the development of food markets: retrospect and prospects
Moschini, G. (2008) · European Review of Agricultural Economics · doi:10.1093/erae/jbn014 · Cited by 63
Intragenic Crop Improvement: Combining the Benefits of Traditional Breeding and Genetic Engineering
Rommens, C. M. T. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0706631 · Cited by 62
Transgenic perennial biofuel feedstocks and strategies for bioconfinement
Kausch, A. P., Hague, J. P., Oliver, M. J., Li, Y., Daniell, H., Mascia, P. N., Watrud, L. S., & Stewart, C. N. (2010) · Biofuels · doi:10.4155/bfs.09.11 · Cited by 61
Can –omics inform a food safety assessment?
Chassy, B. M. (2010) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2010.05.009 · Cited by 58
Time for a New EU Regulatory Framework for GM Crops?
Zetterberg, C., & Björnberg, K. E. (2017) · Journal of Agricultural and Environmental Ethics · doi:10.1007/s10806-017-9664-9 · Cited by 58
Lack of repeatable differential expression patterns between MON810 and comparable commercial varieties of maize
Coll, A., Nadal, A., Palaudelmàs, M., Messeguer, J., Melé, E., Puigdomènech, P., & Pla, M. (2008) · Plant Molecular Biology · doi:10.1007/s11103-008-9355-z · Cited by 57
Ecological Risk Assessment and Regulation for Genetically-Modified Ornamental Plants
Auer, C. A. (2008) · Critical Reviews in Plant Sciences · doi:10.1080/07352680802237162 · Cited by 57
Consumers' perceptions and acceptance of genome editing in agriculture: Insights from the United States of America and Switzerland
Bearth, A., Otten, C. D., & Cohen, A. S. (2024) · Food Research International · doi:10.1016/j.foodres.2024.113982 · Cited by 53
“Golden Rice”, a GMO-product for public good, and the consequences of GE-regulation
Potrykus, I. (2012) · Journal of Plant Biochemistry and Biotechnology · doi:10.1007/s13562-012-0130-5 · Cited by 53
Only half the transcriptomic differences between resistant genetically modified and conventional rice are associated with the transgene
Montero, M., Coll, A., Nadal, A., Messeguer, J., & Pla, M. (2010) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2010.00572.x · Cited by 51
Gene expression profiles of MON810 and comparable non-GM maize varieties cultured in the field are more similar than are those of conventional lines
Coll, A., Nadal, A., Collado, R., Capellades, G., Messeguer, J., Melé, E., Palaudelmàs, M., & Pla, M. (2009) · Transgenic Research · doi:10.1007/s11248-009-9266-z · Cited by 50
Proposed U.S. regulation of gene-edited food animals is not fit for purpose
Eenennaam, A. L. V., Wells, K. D., & Murray, J. D. (2019) · npj Science of Food · doi:10.1038/s41538-019-0035-y · Cited by 53
Processes for regulating genetically modified and gene edited plants
Caradus, J. R. (2023) · GM crops & food · doi:10.1080/21645698.2023.2252947 · Cited by 50
Conservative management of cocaine-packet ingestion: experience in Milan, the main Italian smuggling center of South American cocaine.
Aldrighetti, L. A., Paganelli, M., Giacomelli, M., Villa, G., & Ferla, G. (1996) · PubMed · Cited by 49
Valuing product innovation: genetically engineered varieties in US corn and soybeans
Federico Ciliberto, A., Moschini, G., & Perry, E. (2019) · The RAND Journal of Economics · doi:10.1111/1756-2171.12290 · Cited by 48
A new window of opportunity to reject process-based biotechnology regulation
Marchant, G. E., & Stevens, Y. A. (2015) · GM crops & food · doi:10.1080/21645698.2015.1134406 · Cited by 45
Continents divided
Zilberman, D., Kaplan, S. M., Kim, E., Hochman, G., & Graff, G. D. (2013) · GM crops & food · doi:10.4161/gmcr.26981 · Cited by 47
Evaluating Oversight Systems for Emerging Technologies: A Case Study of Genetically Engineered Organisms
Kuzma, J., Najmaie, P., & Larson, J. S. (2009) · The Journal of Law Medicine & Ethics · doi:10.1111/j.1748-720x.2009.00431.x · Cited by 46
Using metabolomics to estimate unintended effects in transgenic crop plants: problems, promises, and opportunities.
Hoekenga, O. A. (2008) · PubMed Central · Cited by 42
Hitting the mark or falling short with nanotechnology regulation?
Ludlow, K., Bowman, D. M., & Kirk, D. D. (2009) · Trends in biotechnology · doi:10.1016/j.tibtech.2009.07.007 · Cited by 41
Transgenic crops, production risk and agrobiodiversity
Krishna, V. V., Qaim, M., & Zilberman, D. (2015) · European Review of Agricultural Economics · doi:10.1093/erae/jbv012 · Cited by 39
Gourds: Bitter, Bottle, Wax, Snake, Sponge and Ridge
Dhillon, N. P. S., Sanguansil, S., Singh, S. P., Masud, M. A. T., Kumar, P., Bharathi, L. K., Yetışır, H., Huang, R., Canh, D. X., & McCreight, J. D. (2016) · Plant genetics and genomics: crops and models · doi:10.1007/7397_2016_24 · Cited by 38
Gene editing in tree and clonal crops: progress and challenges
Goralogia, G. S., Redick, T. P., & Strauss, S. H. (2021) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/s11627-021-10197-x · Cited by 38
Self-citation
Seeds: The Delivery System for Crop Science
TeKrony, D. M. (2006) · Crop Science · doi:10.2135/cropsci2005.12.0445 · Cited by 38
Accelerating wood domestication in forest trees through genome editing: Advances and prospects
Anders, C., Hoengenaert, L., & Boerjan, W. (2022) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2022.102329 · Cited by 37
Assessing the ecological risks from the persistence and spread of feral populations of insect-resistant transgenic maize
Raybould, A. F., Higgins, L. S., Horak, M. J., Layton, R. J., Storer, N. P., de la Fuente, J. M., & Herman, R. A. (2011) · Transgenic Research · doi:10.1007/s11248-011-9560-4 · Cited by 37
Forests and genetically modified trees
Forestal, U. I. D. O. D. I. (2010) · Cited by 36
Regulatory considerations surrounding the deployment Of Bt-expressing cowpea in Africa: Report of the deliberations of an expert panel
Huesing, J. E., Romeis, J., Ellstrand, N. C., Raybould, A., Hellmich, R. L., Wolt, J. D., Ehlers, J. D., Dabiré-Binso, L. C., Fatokun, C. A., Hokanson, K. E., et al. (2011) · GM Crops · doi:10.4161/gmcr.2.3.18689 · Cited by 35
Plants with genetically modified events combined by conventional breeding: An assessment of the need for additional regulatory data
Pilacinski, W., Crawford, A., Downey, R. K., Harvey, B., Huber, S., Hunst, P., Lahman, L. K., Macintosh, S. C., Pohl, M., Rickard, C., et al. (2010) · Food and Chemical Toxicology · doi:10.1016/j.fct.2010.11.004 · Cited by 35
Resistance is not Futile: It Shapes Insecticide Discovery
Hardy, M. C. (2014) · Insects · doi:10.3390/insects5010227 · Cited by 35
Genomics-Assisted Crop Improvement: An Overview
Varshney, R. K., & Tuberosa, R. (2007) · Springer eBooks · doi:10.1007/978-1-4020-6295-7_1 · Cited by 35
Far-reaching Deleterious Impacts of Regulations on Research and Environmental Studies of Recombinant DNA-modified Perennial Biofuel Crops in the United States
Strauss, S. H., Kershen, D. L., Bouton, J. H., Redick, T. P., Tan, H., & Sedjo, R. A. (2010) · BioScience · doi:10.1525/bio.2010.60.9.10 · Cited by 34
Self-citation
Uniform Expression and Relatively Small Position Effects Characterize Sister Transformants in Maize and Soybean
Betts, S. D., Basu, S., Bolar, J., Booth, R., Chang, S., Cigan, A. M., Farrell, J., Gao, H., Harkins, K. R., Kinney, A. J., et al. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.01209 · Cited by 34
Nutritional and Safety Assessments of Foods and Feeds Nutritionally Improved through Biotechnology: Case Studies: Executive Summary of a Task Force Report by the International Life Sciences Institute, Washington, D.C.
(2007) · Journal of Food Science · doi:10.1111/j.1750-3841.2007.00579.x · Cited by 32
Measurement of endogenous allergens in genetically modified soybeans – Short communication
Ladics, G. S., Budziszewski, G. J., Herman, R. A., Hérouet-Guicheney, C., Joshi, S. S., Lipscomb, E. A., McClain, S., & Ward, J. (2014) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2014.06.006 · Cited by 32
Transgene stability and dispersal in forest trees
Ahuja, M. R. (2009) · Trees · doi:10.1007/s00468-009-0362-8 · Cited by 32
Genomics Interventions in Crop Breeding for Sustainable Agriculture
Kulwal, P. L., Thudi, M., & Varshney, R. K. (2012) · Springer eBooks · doi:10.1007/springerreference_226393 · Cited by 32
Metabolic Regulation of Carotenoid-Enriched Golden Rice Line
Gayen, D., Ghosh, S., Paul, S., Sarkar, S. N., Datta, S. K., & Datta, K. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.01622 · Cited by 31
Stacking transgenic event DAS‐Ø15Ø7‐1 alters maize composition less than traditional breeding
Herman, R. A., Fast, B. J., Scherer, P. N., Brune, A. M., de Cerqueira, D. T. R., Schafer, B. W., Ekmay, R. D., Harrigan, G. G., & Bradfisch, G. A. (2017) · Plant Biotechnology Journal · doi:10.1111/pbi.12713 · Cited by 30
DNA-free mutagenesis of GIGANTEA in Brassica oleracea var. capitata using CRISPR/Cas9 ribonucleoprotein complexes
Park, S., Park, S. H., Jeong, Y. J., Lee, S. B., Pyun, J. W., Kim, S.-Y., Kim, T. H., Kim, S. W., Jeong, J. C., & Kim, C. Y. (2019) · Plant Biotechnology Reports · doi:10.1007/s11816-019-00585-6 · Cited by 29
'Cisgenic' as a product designation
Schubert, D., & Williams, D. S. (2006) · Nature Biotechnology · doi:10.1038/nbt1106-1327 · Cited by 29
The emergence of agbiogenerics
Jefferson, D. J., Graff, G. D., Chi‐Ham, C. L., & Bennett, A. B. (2015) · Nature Biotechnology · doi:10.1038/nbt.3306 · Cited by 28
Genetically modified foods and allergy
Lee, T. H., Ho, M., & Leung, T. (2017) · Hong Kong Medical Journal · doi:10.12809/hkmj166189 · Cited by 28
Economic issues to consider for gene drives
Mitchell, P. D., Brown, Z. S., & McRoberts, N. (2017) · Journal of Responsible Innovation · doi:10.1080/23299460.2017.1407914 · Cited by 30
Field performance of transgenic citrus trees: Assessment of the long-term expression of uidA and nptIItransgenes and its impact on relevant agronomic and phenotypic characteristics
Pons, E., Peris, J. E., & Peña, L. (2012) · BMC Biotechnology · doi:10.1186/1472-6750-12-41 · Cited by 27
From patent law to regulation: the ontological gerrymandering of biotechnology
Carolan, M. (2008) · Environmental Politics · doi:10.1080/09644010802421505 · Cited by 26
Genome Elimination: Translating Basic Research into a Future Tool for Plant Breeding
Comai, L. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001876 · Cited by 27

Authors: Bradford, K. J., Van Deynze, A., Gutterson, N., Parrott, W., & Strauss, S. H.
Affiliations: University of California, Davis (US)
Mendel Biotechnology (United States) (US)
University of Georgia (US)
Oregon State University (US)
Corresponding author: Strauss, Steven H
ORCID: Bradford, Kent J
Gutterson, Neal
Parrott, Wayne
Strauss, Steven H
Venue: Nature Biotechnology
Publisher: Springer Science and Business Media LLC
Published: 2005-04
Volume: 23
Issue: 4
Pages: 439-444
ISSN: 0733-222X (ISSN-L)
1087-0156
1546-1696
DOI: 10.1038/nbt1084
OpenAlex: W2150788885
Cited by: 243
References: 67
Citations by year: 2026: 1 · 2025: 4 · 2024: 6 · 2023: 6 · 2022: 6 · 2021: 5 · 2020: 7 · 2019: 11 · 2018: 5 · 2017: 7 · 2016: 14 · 2015: 7 · 2014: 14 · 2013: 16 · 2012: 14
FWCI: 25.93
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
www.springer.com/tdm (vor)
Locations: Nature Biotechnology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural safety and regulations
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
Keywords: genetically modified crops, regulatory costs, plant breeding, genetic engineering safety
MeSH terms: Agriculture, Biotechnology, Breeding, Genetic Engineering, Crops, Agricultural, Genome, Plant, Genomics, Plants, Genetically Modified, Government Regulation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Regulating transgenic crops sensibly: lessons from plant breeding, biotechnology and genomics

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks