Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
Rodriguez, Raphaël, Miller, Kyle M, Forment, Josep V, Bradshaw, Charles R, Nikan, Mehran, Britton, Sébastien, Oelschlaegel, Tobias, Xhemalce, Blerta, Balasubramanian, Shankar, Jackson, Stephen P·2012·Nature Chemical Biology
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- G-quadruplex-guided cisplatin triggers multiple pathways in targeted chemotherapy and immunotherapyTianzhu Ma, Liu‐Yi Liu, You‐Liang Zeng, Ke Ding, Hang Zhang, Wenting Liu, Qian Cao, Wei Ting Xia, Xushen Xiong, Chao‐Liang Wu et al. · 2024 · Chemical Science
- Relevance of G-quadruplex structures to pharmacogeneticsSimone L. Cree, Martin Alexander Kennedy · 2014 · Frontiers in Pharmacology
- Single-Molecule Analysis of Human Telomere Sequence Interactions with G-quadruplex LigandLing Zhang, Kaixiang Zhang, Sana Rauf, Duo Dong, Yang Liu, Jinghong Li · 2016 · Analytical Chemistry
- Amino‐Acid‐Derived Naphthalenediimides as Versatile G‐Quadruplex BindersDora M. Răsădean, Bin Sheng, Jyotirmayee Dash, Gheorghe Dan Pantoş · 2017 · Chemistry - A European Journal
- Down-Regulation of the Androgen Receptor by G-Quadruplex Ligands Sensitizes Castration-Resistant Prostate Cancer Cells to EnzalutamideMartina Tassinari, Graziella Cimino-Reale, Matteo Nadai, Filippo Doria, Elena Butovskaya, Marta Recagni, Mauro Freccero, Nadia Zaffaroni, Sara N. Richter, Marco Folini · 2018 · Journal of Medicinal Chemistry
- Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replicationIkenna R. Obi, Matilda Rentoft, Vandana Singh, Ján Jamroškovič, Karam Chand, Erik Chorell, Fredrik Westerlund, Nasim Sabouri · 2020 · Nucleic Acids Research
- Profiling dynamic RNA–protein interactions using small-molecule-induced RNA editingKyung W. Seo, Ralph E. Kleiner · 2023 · Nature Chemical Biology
- An Appraisal of Human Mitochondrial DNA Instability: New Insights into the Role of Non-Canonical DNA Structures and Sequence MotifsPedro H. Oliveira, Claudia Lobato da Silva, Joaquim M. S. Cabral · 2013 · PLoS ONE
- In vivo dynamics and regulation of DNA G-quadruplex structures in mammalsZe-Hao Zhang, Sheng Hu Qian, Dengguo Wei, Zhen‐Xia Chen · 2023 · Cell & Bioscience
- Naphthalene diimide‐derivatives G‐quadruplex ligands induce cell proliferation inhibition, mild telomeric dysfunction and cell cycle perturbation in U251MG glioma cellsDaniela Muoio, Francesco Berardinelli, Stefano Leone, Elisa Coluzzi, Alessandra di Masi, Filippo Doria, Mauro Freccero, Antonella Sgura, Marco Folini, Antonio Antoccia · 2018 · FEBS Journal
- Oligonucleotides and microRNAs Targeting Telomerase Subunits in Cancer TherapyAdam Eckburg, Joshua Dein, Joseph Berei, Zachary Schrank, Neelu Puri · 2020 · Cancers
- BG-flow, a new flow cytometry tool for G-quadruplex quantification in fixed cellsAlessio De Magis, Melanie Kastl, Peter Brossart, Annkristin Heine, Katrin Paeschke · 2021 · BMC Biology
- Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of o-BMVC FociTing‐Yuan Tseng, I-Te Chu, Shang-Jyun Lin, Jie Li, Ta‐Chau Chang · 2018 · Molecules
- Porphyrin-templated synthetic G-quartet (PorphySQ): a second prototype of G-quartet-based G-quadruplex ligandHaijun Xu, Loïc Stefan, Romain Haudecoeur, Sophie Vuong, Philippe Richard, Franck Denat, Jean‐Michel Barbe, Claude P. Gros, David Monchaud · 2012 · Organic & Biomolecular Chemistry
- Human telomeric G-quadruplex DNA interactions of N-phenanthroline glycosylamine copper(II) complexesKaterina Duskova, Sara Sierra, M.S. Arias, Lourdes Gude · 2015 · Bioorganic & Medicinal Chemistry
- Selective Luminescent Labeling of DNA and RNA Quadruplexes by π‐Extended Ruthenium Light‐Up ProbesDounia Saadallah, Mehdi Bellakhal, Souheila Amor, Jean‐François Lefebvre, Murielle Chavarot‐Kerlidou, Isabelle Baussanne, Cécile Moucheron, Martine Demeunynck, David Monchaud · 2017 · Chemistry - A European Journal
- Recognition of G-quadruplex topology through hybrid binding with implications in cancer theranosticsYelisetty Venkata Suseela, Pardhasaradhi Satha, N. Arul Murugan, Thimmaiah Govindaraju · 2020 · Theranostics
- G-Quadruplex Structures Colocalize with Transcription Factories and Nuclear Speckles Surrounded by Acetylated and Dimethylated Histones H3Denisa Komůrková, Alena Svobodová Kovaříková, Eva Bártová · 2021 · International Journal of Molecular Sciences
- An Investigation of G-Quadruplex Structural Polymorphism in the Human Telomere Using a Combined Approach of Hydrodynamic Bead Modeling and Molecular Dynamics SimulationHuy T. Le, William L. Dean, Robert Buscaglia, Jonathan Brad Chaires, John O. Trent · 2014 · The Journal of Physical Chemistry B
- Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivativesStephan A. Ohnmacht, Marialuisa Micco, Vanessa Petrucci, Alan K. Todd, Anthony P. Reszka, Mekala Gunaratnam, Marta A. B. R. Carvalho, Mire Zloh, Stephen Neidle · 2012 · Bioorganic & Medicinal Chemistry Letters
- Downregulation of Androgen Receptor Transcription by Promoter G-Quadruplex Stabilization as a Potential Alternative Treatment for Castrate-Resistant Prostate CancerTom Mitchell, Antonio Ramos‐Montoya, Marco Di Antonio, Pierre Murat, Stephan A. Ohnmacht, Marialuisa Micco, Sarah Jurmeister, Lee G.D. Fryer, Shankar Balasubramanian, Stephen Neidle et al. · 2013 · Biochemistry
- Ionic Effects on VEGF G-Quadruplex StabilityByul G. Kim, J.F. Long, David N. Dubins, Tigran V. Chalikian · 2016 · The Journal of Physical Chemistry B
- Quinolizinium as a new fluorescent lysosomotropic probeEmmanouil Zacharioudakis, Tatiana Cañeque, Raúl Custodio, Sebastian Müller, Ana M. Cuadro, Juan J. Vaquero, Raphaël Rodriguez · 2016 · Bioorganic & Medicinal Chemistry Letters
- G-quadruplexes unfolding by RHAU helicaseNassima Meriem Gueddouda, Óscar Mendoza, Dennis Gómez, Anne Bourdoncle, Jean‐Louis Mergny · 2017 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Spotlight on G-Quadruplexes: From Structure and Modulation to Physiological and Pathological RolesMaria Chiara dell’Oca, Roberto Quadri, Giulia Maria Bernini, Luca Menin, Lavinia Grasso, Diego Rondelli, Ozge Yazici, Sarah Sertic, F. Marini, Achille Pellicioli et al. · 2024 · International Journal of Molecular Sciences
- Interaction of Cationic Manganese Porphyrin with G‐Quadruplex Nucleic Acids Probed by Differential Labeling of the Two Faces of the PorphyrinVincent Pradines, Geneviève Pratviel · 2013 · Angewandte Chemie International Edition
- Human Telomeric G-Quadruplex Selective Fluoro-Isoquinolines Induce Apoptosis in Cancer CellsSubhadip Maiti, Puja Saha, Tania Das, Irene Bessi, Harald Schwalbe, Jyotirmayee Dash · 2018 · Bioconjugate Chemistry
- Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection–Mass SpectrometryDeborah A. Flusberg, Noreen F. Rizvi, Victoria D. Kutilek, Christine L. Andrews, Peter Saradjian, Chad Chamberlin, Patrick Curran, Brooke M. Swalm, Solomon D. Kattar, Graham F. Smith et al. · 2018 · SLAS DISCOVERY
- Towards Understanding of Polymorphism of the G-rich Region of Human Papillomavirus Type 52Maja Marušič, Janez Plavec · 2019 · Molecules
- The Functional Consequences of Eukaryotic Topoisomerase 1 Interaction with G-Quadruplex DNAAlexandra Berroyer, Nayun Kim · 2020 · Genes
- Development of a near-infrared fluorescent ligand that visualizes and stabilizes G-quadruplexes by decorating the triphenylamine scaffoldXiaodong Wang, Bing-Ying Yu, Jia-Hong Lin, Yiyong Yan, Ming-Hao Hu · 2021 · Sensors and Actuators B Chemical
- The Pif1 helicase is actively inhibited during meiotic recombination which restrains gene conversion tract lengthDipti Vinayak Vernekar, Giordano Reginato, Céline Adam, Lepakshi Ranjha, Florent Dingli, Marie‐Claude Marsolier‐Kergoat, Damarys Loew, Raphaël Guérois, Bertrand Llorente, Petr Ćejka et al. · 2021 · Nucleic Acids Research
- BrdU immuno-tagged G-quadruplex ligands: a new ligand-guided immunofluorescence approach for tracking G-quadruplexes in cellsThibaut Masson, Corinne Guetta, Eugénie Laigre, Anne Cucchiarini, Patricia Duchambon, Marie‐Paule Teulade‐Fichou, Daniela Verga · 2021 · Nucleic Acids Research
- A Phenotypic Approach to the Discovery of Potent G-Quadruplex Targeted DrugsStephen Neidle · 2024 · Molecules
- Traceable in-cell synthesis and cytoplasm-to-nucleus translocation of a zinc Schiff base complex as a simple and economical anticancer strategyQian Cao, Jing Yang, Hang Zhang, Hao Liang, Gang Yang, Liang‐Nian Ji, Zong‐Wan Mao · 2019 · Chemical Communications
- Specific Recognition of G-Quadruplexes Over Duplex-DNA by a Macromolecular NIR Two-Photon Fluorescent ProbeMarco Deiana, Bastien Mettra, Lara Martínez‐Fernández, Leszek Mateusz Mazur, Krzysztof Pawlik, Chantal Andraud, Marek J. Samoc, Roberto Improta, Cyrille Monnereau, Katarzyna Matczyszyn · 2017 · The Journal of Physical Chemistry Letters
- G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer CellsSarah Di Somma, Jussara Amato, Nunzia Iaccarino, Bruno Pagano, Antonio Randazzo, Giuseppe Portella, Anna Maria Malfitano · 2019 · Cancers
- DNA G-quadruplex structure participates in regulation of lipid metabolism through acyl-CoA binding proteinLijun Xiang, Kangkang Niu, Yuling Peng, Xiaojuan Zhang, Xiaoyü Li, Ruoqi Ye, Guoxing Yu, Guojun Ye, Hui Xiang, Qisheng Song et al. · 2022 · Nucleic Acids Research
- The effect of single nucleotide polymorphisms in G-rich regions of high-risk human papillomaviruses on structural diversity of DNAMaja Marušič, Lea Hošnjak, Petra Krafčíková, Mario Poljak, Viktor Víglaský, Janez Plavec · 2016 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Real-time and quantitative fluorescent live-cell imaging with quadruplex-specific red-edge probe (G4-REP)S.Y. Cindy Yang, Souheila Amor, Aurélien Laguerre, Judy M.Y. Wong, David Monchaud · 2016 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Submolecular dissection reveals strong and specific binding of polyamide–pyridostatin conjugates to human telomere interfaceShankar Mandal, Yusuke Kawamoto, Zhizhou Yue, Kaori Hashiya, Yunxi Cui, Toshikazu Bando, Shankar Pandey, Mohammed Enamul Hoque, Mohammad Akter Hossain, Hiroshi Sugiyama et al. · 2019 · Nucleic Acids Research
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- DNA supercoiling-mediated G4/R-loop formation tunes transcription by controlling the access of RNA polymeraseJihee Hwang, Chun-Ying Lee, Sumitabha Brahmachari, Shubham Tripathi, Tapas Paul, Huijin Lee, Alanna Craig, Taekjip Ha, Sua Myong · 2025 · Nature Communications
- Target identification of a macrocyclic hexaoxazole G-quadruplex ligand using post-target-binding visualizationMizuho Yasuda, Yue Ma, Sachiko Okabe, Yuki Wakabayashi, Dongdong Su, Young‐Tae Chang, Hiroyuki Seimiya, Masayuki Tera, Kazuo Nagasawa · 2020 · Chemical Communications
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