Pre-bilaterian origin of the blastoporal axial organizer

Efficient genome editing in zebrafish using a CRISPR-Cas system

Hwang, W. Y., Fu, Y., Reyon, D., Maeder, M. L., Tsai, S. Q., Sander, J. D., Peterson, R. T., Yeh, J.-R. J., & Joung, J. K. (2013) · Nature Biotechnology · doi:10.1038/nbt.2501 · Cited by 2,937 · see citing works

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

Sasai, Y. (1994) · Cell · doi:10.1016/0092-8674(94)90068-x · Cited by 1,122 · see citing works

über Induktion von Embryonalanlagen durch Implantation artfremder Organisatoren

Spemann, H., & Mangold, H. (1924) · Development Genes and Evolution · doi:10.1007/bf02108176 · Cited by 833 · see citing works

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

Bouwmeester, T., Kim, S.-H., Sasai, Y., Lu, B., & Robertis, E. M. D. (1996) · Nature · doi:10.1038/382595a0 · Cited by 759 · see citing works

DORSAL-VENTRAL PATTERNING AND NEURAL INDUCTION IN <i>XENOPUS</i> EMBRYOS

De Robertis, E. M., & Kuroda, H. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.011403.154124 · Cited by 671 · see citing works

Unexpected complexity of the Wnt gene family in a sea anemone

Kusserow, A., Pang, K., Sturm, C., Hrouda, M., Lentfer, J., Schmidt, H. A., Technau, U., von Haeseler, A., Hobmayer, B., Martindale, M. Q., et al. (2005) · Nature · doi:10.1038/nature03158 · Cited by 599 · see citing works

Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling.

Funayama, N., Fagotto, F., McCrea, P. D., & Gumbiner, B. M. (1995) · The Journal of Cell Biology · doi:10.1083/jcb.128.5.959 · Cited by 545 · see citing works

Injected Wnt RNA induces a complete body axis in Xenopus embryos

Sokol, S. Y., Christian, J. L., Moon, R. T., & Melton, D. A. (1991) · Cell · doi:10.1016/0092-8674(91)90069-b · Cited by 501 · see citing works

Nuclear β-catenin is required to specify vegetal cell fates in the sea urchin embryo

Logan, C. Y., Miller, J. R., Ferkowicz, M. J., & McClay, D. R. (1999) · Development · doi:10.1242/dev.126.2.345 · Cited by 456 · see citing works

An ancient role for nuclear β-catenin in the evolution of axial polarity and germ layer segregation

Wikramanayake, A. H., Hong, M., Lee, P. N., Pang, K., Byrum, C. A., Bince, J. M., Xu, R., & Martindale, M. Q. (2003) · Nature · doi:10.1038/nature02113 · Cited by 324 · see citing works

Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.

Dominguez, I. M., Itoh, K., & Sokol, S. Y. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.18.8498 · Cited by 316 · see citing works

Multiple Wnts are involved in Hydra organizer formation and regeneration

Lengfeld, T., Watanabe, H., Simakov, O., Lindgens, D., Gee, L., Law, L. Y., Schmidt, H. A., Özbek, S., Bode, H. R., & Holstein, T. W. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.02.004 · Cited by 307 · see citing works

The production of new hydranths in Hydra by the insertion of small grafts

Browne, E. N. (1909) · Journal of Experimental Zoology · doi:10.1002/jez.1400070102 · Cited by 281 · see citing works

β-catenin mediates the specification of endoderm cells in ascidian embryos

Imai, K. S., Takada, N., Satoh, N., & Satou, Y. (2000) · Development · doi:10.1242/dev.127.14.3009 · Cited by 236 · see citing works

Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled

Sokol, S. Y., Klingensmith, J., Perrimon, N., & Itoh, K. (1995) · Development · doi:10.1242/dev.121.6.1637 · Cited by 189 · see citing works

A Complete Second Gut Induced by Transplanted Micromeres in the Sea Urchin Embryo

Ransick, A., & Davidson, E. H. (1993) · Science · doi:10.1126/science.8438164 · Cited by 186 · see citing works

A WNT of things to come: Evolution of Wnt signaling and polarity in cnidarians

LEE, P., PANG, K., Matus, D. Q., & Martindale, M. Q. (2006) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2006.05.002 · Cited by 185 · see citing works

1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3β

Kunick, C., Lauenroth, K., Leost, M., Meijer, L., & Lemcke, T. (2003) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2003.10.062 · Cited by 180 · see citing works

The Wnt code: cnidarians signal the way

Guder, C., Philipp, I., Lengfeld, T., Watanabe, H., Hobmayer, B., & Holstein, T. W. (2006) · Oncogene · doi:10.1038/sj.onc.1210052 · Cited by 177 · see citing works

Asymmetric expression of the BMP antagonists chordin and gremlin in the sea anemone Nematostella vectensis: Implications for the evolution of axial patterning

Rentzsch, F., Anton, R., Saina, M., Hammerschmidt, M., Holstein, T. W., & Technau, U. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.06.003 · Cited by 170 · see citing works

Analysis of forkhead and snail expression reveals epithelial–mesenchymal transitions during embryonic and larval development of Nematostella vectensis

Fritzenwanker, J. H., Saina, M., & Technau, U. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.08.014 · Cited by 165 · see citing works

TALEN and CRISPR/Cas9-mediated genome editing in the early-branching metazoan Nematostella vectensis

Ikmi, A., McKinney, S. A., Delventhal, K. M., & Gibson, M. C. (2014) · Nature Communications · doi:10.1038/ncomms6486 · Cited by 165 · see citing works

A muscle-specific transgenic reporter line of the sea anemone, <i>Nematostella vectensis</i>

Renfer, E., Amon-Hassenzahl, A., Steinmetz, P. R. H., & Technau, U. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909148107 · Cited by 164 · see citing works

A Framework for the Establishment of a Cnidarian Gene Regulatory Network for “Endomesoderm” Specification: The Inputs of ß-Catenin/TCF Signaling

Röttinger, E., Dahlin, P., & Martindale, M. Q. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1003164 · Cited by 140 · see citing works

Early development and axis specification in the sea anemone Nematostella vectensis

Fritzenwanker, J. H., Genikhovich, G., Kraus, Y. A., & Technau, U. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.07.029 · Cited by 140 · see citing works

BMPs and Chordin regulate patterning of the directive axis in a sea anemone

Saina, M., Genikhovich, G., Renfer, E., & Technau, U. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900151106 · Cited by 138 · see citing works

Asymmetric developmental potential along the animal–vegetal axis in the anthozoan cnidarian, Nematostella vectensis, is mediated by Dishevelled

Lee, P. N., Kumburegama, S., Marlow, H. Q., Martindale, M. Q., & Wikramanayake, A. H. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.05.040 · Cited by 135 · see citing works

Ordered progression of nematogenesis from stem cells through differentiation stages in the tentacle bulb of Clytia hemisphaerica (Hydrozoa, Cnidaria)

Denker, E., Manuel, M., Leclère, L., Guyader, H. L., & Rabet, N. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.12.023 · Cited by 130 · see citing works

Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints

Genikhovich, G., Fried, P., Prünster, M. M., Schinko, J. B., Gilles, A. F., Fredman, D., Meier, K., Iber, D., & Technau, U. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.02.035 · Cited by 113 · see citing works

β-catenin plays a central role in setting up the head organizer in hydra

Gee, L., Hartig, J. V., Law, L. Y., Wittlieb, J., Khalturin, K., Bosch, T. C. G., & Bode, H. R. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2009.12.036 · Cited by 105 · see citing works

Induction of Spawning in the Starlet Sea Anemone Nematostella vectensis , In Vitro Fertilization of Gametes, and Dejellying of ZygotesPreprint

Genikhovich, G., & Technau, U. (2009) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot5281 · Cited by 91 · see citing works

β-Catenin is required for the establishment of vegetal embryonic fates in the nemertean, Cerebratulus lacteus

Henry, J. J., Perry, K. J., Wever, J., Seaver, E. C., & Martindale, M. Q. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.02.042 · Cited by 87 · see citing works

Ectopic activation of the canonical wnt signaling pathway affects ectodermal patterning along the primary axis during larval development in the anthozoan Nematostella vectensis

Marlow, H. Q., Matus, D. Q., & Martindale, M. Q. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.05.022 · Cited by 81 · see citing works

Sequential actions of β-catenin and Bmp pattern the oral nerve net in Nematostella vectensis

Watanabe, H., Kuhn, A., Fushiki, M., Agata, K., Özbek, S., Fujisawa, T., & Holstein, T. W. (2014) · Nature Communications · doi:10.1038/ncomms6536 · Cited by 79 · see citing works

An organizing activity is required for head patterning and cell fate specification in the polychaete annelid Capitella teleta: New insights into cell–cell signaling in Lophotrochozoa

Amiel, A., Henry, J. J., & Seaver, E. C. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.04.011 · Cited by 69 · see citing works

In Situ Hybridization of Starlet Sea Anemone (Nematostella vectensis) Embryos, Larvae, and PolypsPreprint

Genikhovich, G., & Technau, U. (2009) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot5282 · Cited by 66 · see citing works

The blastoporal organiser of a sea anemone

Kraus, Y. A., Fritzenwanker, J. H., Genikhovich, G., & Technau, U. (2007) · Current Biology · doi:10.1016/j.cub.2007.08.017 · Cited by 56 · see citing works

Frizzled1/2/7 signaling directs β-catenin nuclearisation and initiates endoderm specification in macromeres during sea urchin embryogenesis

Lhomond, G., McClay, D. R., Gache, C., & Croce, J. C. (2012) · Development · doi:10.1242/dev.072215 · Cited by 42 · see citing works

-catenin and Early Development in the Gastropod, Crepidula fornicata

Henry, J. J., Perry, K. J., & Martindale, M. Q. (2010) · Integrative and Comparative Biology · doi:10.1093/icb/icq076 · Cited by 42 · see citing works

Cytoplasmic localization and chordamesoderm induction in the frog embryo

Gimlich, R. L. (1985) · Development · doi:10.1242/dev.89.supplement.89 · Cited by 40 · see citing works

Complex functions of Mef2 splice variants in the differentiation of endoderm and of a neuronal cell type in a sea anemone

Genikhovich, G., & Technau, U. (2011) · Development · doi:10.1242/dev.068122 · Cited by 35 · see citing works

Secondary embryonic axis formation by transplantation of D quadrant micromeres in an oligochaete annelid

Nakamoto, A., Nagy, L. M., & Shimizu, T. (2010) · Development · doi:10.1242/dev.055384 · Cited by 32 · see citing works

An organizing region in metamorphosing hydrozoan planula larvae - stimulation of axis formation in both larval and in adult tissue

Stumpf, M., Will, B., Wittig, K., Kasper, J., Fischer, B., Schmich, J., Seipp, S., & Leitz, T. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.082738ms · Cited by 28 · see citing works

Flesh flies (Diptera: Sarcophagidae: Sarcophaginae) from the Colombian Guajira biogeographic province, an approach to their ecology and distribution

Valverde-Castro, C., Buenaventura, E., Sánchez-Rodríguez, J. D., et al. (2017) · Zoologia (Curitiba) · doi:10.3897/zoologia.34.e12277 · Cited by 28 · see citing works

Induction of Secondary Embryos by Intra‐ and Interspecific Grafts of Center Cells under the blastopore in Horseshoe Crabs

Itow, T., Kenmochi, S., & 望月多恵子 (1991) · Development Growth & Differentiation · doi:10.1111/j.1440-169x.1991.00251.x · Cited by 22 · see citing works

Organizer regions in marine colonial hydrozoans

Mayorova, T. D., Kosevich, I. A., Dulin, N. O., Savina, E. O., & Kraus, Y. A. (2015) · Zoology · doi:10.1016/j.zool.2014.12.001 · Cited by 12 · see citing works

Back to the Basics: Cnidarians Start to Fire

Bosch, T. C. G., Klimovich, A., Domazet-Lošo, T., Gründer, S., Holstein, T. W., Jékely, G., Miller, D. J., Murillo-Rincon, A. P., Rentzsch, F., Richards, G. S., et al. (2017) · Trends in Neurosciences · doi:10.1016/j.tins.2016.11.005 · Cited by 144 · see citing works

The invertebrate chordate amphioxus gives clues to vertebrate origins

Holland, L. Z., & Holland, N. D. (2022) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2021.12.011 · Cited by 13 · see citing works

Chordate roots of the vertebrate nervous system: expanding the molecular toolkit

Holland, L. Z. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2703 · Cited by 114 · see citing works

Did the first chordates organize without the organizer?

Kourakis, M. J., & Smith, W. C. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.07.002 · Cited by 23 · see citing works

Facts and fancies about early fossil chordates and vertebrates

Janvier, P. (2015) · Nature · doi:10.1038/nature14437 · Cited by 108 · see citing works

Origin and evolution of the chordate central nervous system: insights from amphioxus genoarchitecture

Albuixech-Crespo, B., Herrera-Úbeda, C., Marfany, G., Irimia, M., & García‐Fernàndez, J. (2017) · The International Journal of Developmental Biology · doi:10.1387/ijdb.170258jg · Cited by 10 · see citing works