Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis

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Direct regulation of TWIST by HIF-1α promotes metastasis

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Altered Telomeres in Tumors with <i>ATRX</i> and <i>DAXX</i> Mutations

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Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

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Integrated genomic characterization of adrenocortical carcinoma

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Hypoxia and hypoxia-inducible factors: master regulators of metastasis

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p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

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Loss of tight junction barrier function and its role in cancer metastasis

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An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia

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Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors.

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Selection of Invasive and Metastatic Subpopulations from a Human Lung Adenocarcinoma Cell Line

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Regulation of Angiogenesis by Oxygen and Metabolism

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Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial

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Slug Antagonizes p53-Mediated Apoptosis of Hematopoietic Progenitors by Repressing puma

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Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells

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ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

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TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

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The EMT regulator slug and lung carcinogenesis

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Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?

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Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients

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Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX

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DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition

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Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment

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Transcription RepressorSlugPromotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma

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The Pax3–FKHR oncoprotein is unresponsive to the Pax3‐associated repressor hDaxx

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EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes

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Slug Confers Resistance to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

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GSK3β controls epithelial–mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug

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Identification of Five Driver Gene Mutations in Patients with Treatment-Naïve Lung Adenocarcinoma in Taiwan

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Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation.Preprint

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Regulation of Membrane-Type 4 Matrix Metalloproteinase by SLUG Contributes to Hypoxia-Mediated Metastasis

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Negative Modulation of Androgen Receptor Transcriptional Activity by Daxx

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Daxx Cooperates with the Axin/HIPK2/p53 Complex to Induce Cell Death

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Dysregulated expression of Slug, vimentin, and E‐cadherin correlates with poor clinical outcome in patients with basal‐like breast cancer

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Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation

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DAXX, FLASH, and FAF-1 Modulate Mineralocorticoid and Glucocorticoid Receptor-Mediated Transcription in Hippocampal Cells—Toward a Basis for the Opposite Actions Elicited by Two Nuclear Receptors?

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The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition

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The Transcriptional Repressor hDaxx Potentiates p53-dependent Apoptosis

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HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer

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Daxx mediates SUMO-dependent transcriptional control and subnuclear compartmentalization

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CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells

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In vivo binding to and functional repression of the VDR gene promoter by SLUG in human breast cells

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Death Domain-associated Protein DAXX Promotes Ovarian Cancer Development and Chemoresistance

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Daxx Represses Expression of a Subset of Antiapoptotic Genes Regulated by Nuclear Factor-κB

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Slug Promotes Survival during Metastasis through Suppression of Puma-Mediated Apoptosis

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Regulation of c-met expression by transcription repressor Daxx

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Slug is temporally regulated by cyclin E in cell cycle and controls genome stability

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Death Domain-associated Protein 6 (Daxx) Selectively Represses IL-6 Transcription through Histone Deacetylase 1 (HDAC1)-mediated Histone Deacetylation in Macrophages

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Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46

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Slug is associated with poor survival in squamous cell carcinoma of the lung.

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Axin bridges Daxx to p53

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Daxx inhibits muscle differentiation by repressing E2A‐mediated transcription

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HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19

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Synthetic circular RNA functions as a miR-21 sponge to suppress gastric carcinoma cell proliferation

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Eco‐Friendly Higher Manganese Silicide Thermoelectric Materials: Progress and Future Challenges

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Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX

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Targeting Hypoxia-Inducible Factor-1-Mediated Metastasis for Cancer Therapy

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MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop

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Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis

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Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways

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DAXX, as a Tumor Suppressor, Impacts DNA Damage Repair and Sensitizes BRCA-Proficient TNBC Cells to PARP Inhibitors

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Short-Term Responders of Non–Small Cell Lung Cancer Patients to EGFR Tyrosine Kinase Inhibitors Display High Prevalence of TP53 Mutations and Primary Resistance Mechanisms

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20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1

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Glucose-Regulated Protein 78 Signaling Regulates Hypoxia-Induced Epithelial–Mesenchymal Transition in A549 Cells

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SRY-related high-mobility-group box 4: Crucial regulators of the EMT in cancer

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DAXX Mutation Status of Embolization-Treated Neuroendocrine Tumors Predicts Shorter Time to Hepatic Progression

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MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis

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DAXX inhibits cancer stemness and epithelial–mesenchymal transition in gastric cancer

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Long intergenic non-protein coding RNA 00475 silencing acts as a tumor suppressor in glioma under hypoxic condition by impairing microRNA-449b-5p-dependent AGAP2 up-regulation

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Induction of Slug by Chronic Exposure to Single-Walled Carbon Nanotubes Promotes Tumor Formation and Metastasis

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MiR-199a-5p–HIF-1α-STAT3 Positive Feedback Loop Contributes to the Progression of Non-Small Cell Lung Cancer

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Multifunctional biomaterials that modulate oxygen levels in the tumor microenvironment

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Molecular mechanisms of microRNA-301a during tumor progression and metastasis

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RUNX1-IT1 acts as a scaffold of STAT1 and NuRD complex to promote ROS-mediated NF-κB activation and ovarian cancer progression

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SLUG/HIF1-α/miR-221 regulatory circuit in endometrial cancer

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Ginsenoside CK Inhibits TGF‐β‐Induced Epithelial‐Mesenchymal Transition in A549 Cell via SIRT1

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A method establishment and comparison of in vivo lung cancer model development platforms for evaluation of tumour metabolism and pharmaceutical efficacy

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Death Domain-Associated Protein Promotes Colon Cancer Metastasis through Direct Interaction with ZEB1

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Absence of EpCAM in cervical cancer cells is involved in slug induced epithelial-mesenchymal transition

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Dynamic Activity of Histone H3-Specific Chaperone Complexes in Oncogenesis

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Epigenetic Metal‐Organic Framework Nanoagonist Overcomes Triple Defenses to Enable Effective Chemo‐Metalloimmunotherapy in Platinum‐Resistant Ovarian Cancer

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Exploring the Role of Epithelial–Mesenchymal Transcriptional Factors Involved in Hematological Malignancy and Solid Tumors: A Systematic Review

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HDAC1 Mediates Immunosuppression of the Tumor Microenvironment in Non-Small Cell Lung Cancer

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Reduced DAXX Expression Is Associated with Reduced CD24 Expression in Colorectal Cancer

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Black phosphorus conjugation of chemotherapeutic ginsenoside Rg3: enhancing targeted multimodal nanotheranostics against lung cancer metastasis

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HDAC1 promotes the migration of human myeloma cells via regulation of the lncRNA/Slug axis

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Arsenic Sulfide Inhibits Hepatocellular Carcinoma Metastasis by Suppressing the HIF-1α/VEGF Pathway

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ITCH facilitates proteasomal degradation of TXNIP in hypoxia‐ induced lung cancer cells

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Death-Associated Protein 6 (Daxx) Alleviates Liver Fibrosis by Modulating Smad2 Acetylation

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Aberrantly expressed HIF-1α enhances HCC stem cell-like traits via Wnt/β-catenin signaling activation after insufficient radiofrequency ablation

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Bone marrow mesenchymal/fibroblastic stromal cells induce a distinctive EMT-like phenotype in AML cells

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Sinomenine inhibits ovarian cancer cell growth and metastasis by mediating the Wnt/β-catenin pathway via targeting MCM2

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SLUG is upregulated and induces epithelial mesenchymal transition in canine oral squamous cell carcinoma

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HypoxamiRs in pancreatic cancer: master regulators of the hypoxic tumor microenvironment

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HIF-1α Levels in patients receiving chemoradiotherapy for locally advanced non-small cell lung carcinoma

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SNX-2112, an Hsp90 inhibitor, suppresses cervical cancer cells proliferation, migration, and invasion by inhibiting the Akt/mTOR signaling pathway

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Rationally engineered Losmapimod encapsulating polymeric nanoparticles for treatment of human multiple myeloma cells

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Association of Mental Health-Related Proteins DAXX, DRD3, and DISC1 With the Progression and Prognosis of Chondrosarcoma

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Identifying crucial lncRNAs and mRNAs in hypoxia-induced A549 lung cancer cells and investigating their underlying mechanisms via high-throughput sequencing

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Oxygen concentration modulates HDAC1-Mediated regulation of osteogenic signaling pathways in dental pulp cells

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DAXX-dependent H3.3 deposition maintains myoblast cell identity independently of other histone chaperone complexes

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Loss of DAXX/ATRX Protein Expression Results in Ischemia Resistance and Radiation Sensitivity in Pancreatic Neuroendocrine Tumor Cells and Is Associated with Improved Response to Trans-Arterial Radioembolization

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NUSAP1 Recruits DAXX to Suppress HIF‐Driven Triple‐Negative Breast Cancer Progression

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The Dynamic Regulation of Daxx-Mediated Transcriptional Inhibition by SUMO and PML NBs

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A Comparison of Death Domain-Associated Protein 6 in Different Endometrial Carcinomas Histotypes

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MiR-301a transcriptionally activated by HIF-2α promotes hypoxia-induced epithelial-mesenchymal transition by targeting TP63 in pancreatic cancer

Zhang, K.-D., Hu, B., Cen, G., Yang, Y., Chen, W., Guo, Z., Wang, X., Zhao, Q. C., & Qiu, Z. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i19.2348

Addendum: Glucose-Regulated Protein 78 Signaling Regulates Hypoxia-Induced Epithelial–Mesenchymal Transition in A549 Cells

Sun, L., Chen, C., Zhang, J., Wang, J., Yang, C.-Z., & Lin, L. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.637227

Additional file 2 of The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation

Chen, L., Wang, L. Y., Ren, Y.-X., Pang, Z., Liu, Y., Sun, X.-D., Tu, J., Zhi, Z., Qin, Y., Sun, L., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13278831

Additional file 1 of The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation

Chen, L.-Y., Wang, L. Y., Ren, Y.-X., Pang, Z., Liu, Y., Sun, X.-D., Tu, J., Zhi, Z., Qin, Y., Sun, L., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13278828

Additional file 1 of Absence of EpCAM in cervical cancer cells is involved in slug induced epithelial-mesenchymal transition

Liu, X., Feng, Q., 张燕茹, Zheng, P., & Cui, N. (2021) · Figshare · doi:10.6084/m9.figshare.14196907

Slug is a key mediator of hypoxia induced cadherin switch in HNSCC: Correlations with poor prognosis

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Dexamethasone inhibits hypoxia-induced epithelial-mesenchymal transition in colon cancer

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