The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorus ratios
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis
Almutairi, A., Rossin, R., Shokeen, M., Hagooly, A., Ananth, A., Capoccia, B., Guillaudeu, S., Abendschein, D., Anderson, C. J., Welch, M. J., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811757106 · Cited by 235
Research works printed but not linked: 47
- Ornelas-Megiatto, C., Wich, P. R. & Frechet, J. M. Polyphosphonium polymers for siRNA delivery: an efficient and nontoxic alternative to polyammonium carriers. J. Am. Chem. Soc. 134, 1902–1905 (2012). · DOI
- Cui, L. N. et al. Conjugation chemistry through acetals toward a dextran-based delivery system for controlled release of siRNA. J. Am. Chem. Soc. 134, 15840–15848 (2012). · DOI
- Cohen, J. L. et al. Acid-degradable cationic dextran particles for the delivery of siRNA therapeutics. Bioconjugate Chem. 22, 1056–1065 (2011). · DOI
- Cohen, J. A. et al. Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells. Adv. Mater. 22, 3593–3597 (2010). · DOI
- Mastrobattista, E. & Hennink, W. E. Polymers for gene delivery: charged for success. Nat. Mater. 11, 10–12 (2011). · DOI
- Anderson, D. G. et al. A polymer library approach to suicide gene therapy for cancer. Proc. Natl Acad. Sci. 101, 16028–16033 (2004). · DOI · Paper page
- Siegwart, D. J. et al. Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proc. Natl Acad. Sci. 108, 12996–13001 (2011). · DOI · Paper page
- Wagner, E. Strategies to improve DNA polyplexes for in vivo gene transfer: will ‘artificial viruses’ be the answer? Pharm. Res. 21, 8–14 (2004). · DOI · Paper page
- Liu, H., Wang, H., Yang, W. & Cheng, Y. Disulfide cross-linked low generation dendrimers with high gene transfection efficacy, low cytotoxicity, and low cost. J. Am. Chem. Soc. 134, 17680–17687 (2012). · DOI · Paper page
- Zhou, J. et al. Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. Nat. Mater. 11, 82–90 (2011). · DOI · Paper page
- Woodrow, K. A. et al. Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nat. Mater. 8, 526–533 (2009). · DOI · Paper page
- Zeng, H., Little, H. C., Tiambeng, T. N., Williams, G. A. & Guan, Z. Multifunctional dendronized peptide polymer platform for safe and effective siRNA delivery. J. Am. Chem. Soc. 135, 4962–4965 (2013). · DOI
- Yuba, E. et al. Effect of unsaturated alkyl chains on transfection activity of poly(amidoamine) dendron-bearing lipids. J. Control. Release 160, 552–560 (2012). · DOI
- Kulkarni, A., DeFrees, K., Hyun, S. H. & Thompson, D. H. Pendant polymer:amino-beta-cyclodextrin:siRNA guest:host nanoparticles as efficient vectors for gene silencing. J. Am. Chem. Soc. 134, 7596–7599 (2012). · DOI
- Huang, S. et al. Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma. Biomaterials 32, 6832–6838 (2011). · DOI · Paper page
- Patil, M. L., Zhang, M. & Minko, T. Multifunctional triblock Nanocarrier (PAMAM-PEG-PLL) for the efficient intracellular siRNA delivery and gene silencing. ACS Nano 5, 1877–1887 (2011). · DOI · Paper page
- Su, H. et al. Amphiphilic starlike dextran wrapped superparamagnetic iron oxide nanoparticle clsuters as effective magnetic resonance imaging probes. Biomaterials 34, 1193–1203 (2013). · DOI
- Muller, K., Faeh, C. & Diederich, F. Fluorine in pharmaceuticals: looking beyond intuition. Science 317, 1881–1886 (2007). · DOI · Paper page
- Purser, S., Moore, P. R., Swallow, S. & Gouverneur, V. Fluorine in medicinal chemistry. Chem. Soc. Rev. 37, 320–330 (2008). · DOI · Paper page
- Liu, W. et al. Oxidative aliphatic C-H fluorination with fluoride ion catalyzed by a manganese porphyrin. Science 337, 1322–1325 (2012). · DOI · Paper page
- Buer, B. C., Meagher, J. L., Stuckey, J. A. & Marsh, E. N. Structural basis for the enhanced stability of highly fluorinated proteins. Proc. Natl Acad. Sci. 109, 4810–4815 (2012). · DOI
- Wang, Y. et al. Fluorinated graphene for promoting neuro-induction of stem cells. Adv. Mater. 24, 4285–4290 (2012). · DOI · Paper page
- Takaoka, Y. et al. Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging. Nat. Chem. 1, 557–561 (2009). · DOI · Paper page
- Lee, E. et al. A fluoride-derived electrophilic late-stage fluorination reagent for PET imaging. Science 334, 639–642 (2011). · DOI · Paper page
- Horvath, I. T. & Rabai, J. Facile catalyst separation without water: fluorous biphase hydroformylation of olefins. Science 266, 72–75 (1994). · DOI · Paper page
- Xiong, S. D. et al. Cationic fluorine-containing amphiphilic graft copolymers as DNA carriers. Biomaterials 31, 2673–2685 (2010). · DOI
- Kasuya, M. C. Z., Nakano, S., Katayama, R. & Hatanaka, K. Evaluation of the hydrophobicity of perfluoroalkyl chains in amphiphilic compounds that are incorporated into cell membrane. J. Fluorine Chem. 132, 202–206 (2011). · DOI
- Neil, E. & Marsh, G. Towards the nonstick egg: designing fluorous proteins. Chem. Biol. 7, R153–R157 (2000). · doi:10.1016/s1074-5521(00)00139-3
- Percec, V., Imam, M. R., Peterca, M. & Leowanawat, P. Self-organizable vesicular columns assembled from polymers dendronized with semifluorinated Janus dendrimers act as reverse thermal actuators. J. Am. Chem. Soc. 134, 4408–4420 (2012). · DOI
- Percec, V. et al. Self-organization of supramolecular helical dendrimers into complex electronic materials. Nature 419, 384–387 (2002). · doi:10.1038/nature01072
- Brittain, S. M., Ficarro, S. B., Brock, A. & Peters, E. C. Enrichment and analysis of peptide subsets using fluorous affinity tags and mass spectrometry. Nat. Biotechnol. 23, 463–468 (2005). · DOI · Paper page
- Tomalia, D. A. Interview: An architectural journey: from trees, dendrons/dendrimers to nanomedicine. Interview by Hannah Stanwix. Nanomedicine 7, 953–956 (2012). · DOI
- Tomalia, D. A. Dendritic effects: dependency of dendritic nano-periodic property patterns on critical nanoscale design parameters (CNDPs). N. J. Chem. 36, 264–281 (2012). · DOI
- Menjoge, A. R., Kannan, R. M. & Tomalia, D. A. Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications. Drug Discov. Today 15, 171–185 (2010). · DOI · Paper page
- Lee, C. C., MacKay, J. A., Frechet, J. M. & Szoka, F. C. Designing dendrimers for biological applications. Nat. Biotechnol. 23, 1517–1526 (2005). · DOI · Paper page
- Lee, C. C. et al. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc. Natl Acad. Sci. 103, 16649–16654 (2006). · DOI · Paper page
- Caminade, A. M., Turrin, C. O., Sutra, P. & Majoral, J. P. Fluorinated dendrimers. Curr. Opin. Colloid. Interf. Sci. 8, 282–295 (2003). · DOI
- Criscione, J. M. et al. Self-assembly of pH-responsive fluorinated dendrimer-based particulates for drug delivery and noninvasive imaging. Biomaterials 30, 3946–3955 (2009). · DOI
- Vierling, P., Santaella, C. & Greiner, J. Highly fluorinated amphiphiles as drug and gene carrier and delivery systems. J. Fluorine Chem. 107, 337–354 (2001). · doi:10.1016/s0022-1139(00)00378-x
- Klein, E. et al. “HFP” fluorinated cationic lipids for enhanced lipoplex stability and gene delivery. Bioconjugate Chem. 21, 360–371 (2010). · DOI
- Kim, T. I., Bai, C. Z., Nam, K. & Park, J. S. Comparison between arginine conjugated PAMAM dendrimers with structural diversity for gene delivery systems. J. Control. Release 136, 132–139 (2009). · DOI
- Alameh, M. et al. Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery. Int. J. Nanomed. 7, 1399–1414 (2012).
- Breunig, M., Lungwitz, U., Liebl, R. & Goepferich, A. Breaking up the correlation between efficacy and toxicity for nonviral gene delivery. Proc. Natl Acad. Sci. 104, 14454–14459 (2007). · DOI · Paper page
- Wen, Y. et al. Serum tolerance and endosomal escape capacity of histidine-modified pDNA-loaded complexes based on polyamidoamine dendrimer derivatives. Biomaterials 33, 8111–8121 (2012). · DOI
- Zhang, Q., Chen, S., Zhuo, R. X., Zhang, X. Z. & Cheng, S. X. Self-assembled terplexes for targeted gene delivery with improved transfection. Bioconjugate Chem. 21, 2086–2092 (2010). · DOI
- Maksimenko, A. V. et al. Optimisation of dendrimer-mediated gene transfer by anionic oligomers. J. Gene Med. 5, 61–71 (2003). · DOI
- Santos, J. L. et al. Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells. J. Control. Release 144, 55–64 (2010). · DOI · Paper page
Cited by
Xu, J., Lv, J., Zhuang, Q., Yang, Z., Cao, Z., Xu, L., Pei, P., Wang, C., Wu, H., Dong, Z., et al. (2020) · Nature Nanotechnology · doi:10.1038/s41565-020-00781-4 · Cited by 561
Self-citationZhang, C., Yan, K., Fu, C., Peng, H., Hawker, C. J., & Whittaker, A. K. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00632 · Cited by 493
Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing
Zhang, S., Shen, J., Li, D., & Cheng, Y. (2021) · Theranostics · doi:10.7150/thno.47007 · Cited by 430
Self-citationSurface-Engineered Dendrimers in Gene Delivery
Yang, J., Zhang, Q., Chang, H., & Cheng, Y. (2015) · Chemical Reviews · doi:10.1021/cr500542t · Cited by 429
Self-citationPolymeric Delivery of Therapeutic Nucleic Acids
Kumar, R., Santa Chalarca, C. F., Bockman, M. R., Bruggen, C. V., Grimme, C. J., Dalal, R. J., Hanson, M. G., Hexum, J. K., & Reineke, T. M. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00997 · Cited by 365
Fusogenic Reactive Oxygen Species Triggered Charge‐Reversal Vector for Effective Gene Delivery
Liu, X., Xiang, J., Zhu, D., Jiang, L., Zhou, Z., Tang, J., Liu, X., Huang, Y., & Shen, Y. (2016) · Advanced Materials · doi:10.1002/adma.201504288 · Cited by 353
The fluorination effect of fluoroamphiphiles in cytosolic protein delivery
Zhang, Z., Shen, W., Ling, J., Yan, Y., Hu, J., & Cheng, Y. (2018) · Nature Communications · doi:10.1038/s41467-018-03779-8 · Cited by 339
Self-citationWu, H., Li, F., Shao, W., Gao, J., & Ling, D. (2019) · ACS Central Science · doi:10.1021/acscentsci.8b00850 · Cited by 338
Fluoropolymers in Biomedical Applications: State-of-the-Art and Future Perspectives
Lv, J., & Cheng, Y. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00258e · Cited by 316
Self-citationArtificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice
Li, L., Song, L., Liu, X., Yang, X., Li, X., He, T., Wang, N., Yang, S., Yu, C., Yin, T., et al. (2017) · ACS Nano · doi:10.1021/acsnano.6b04261 · Cited by 244
Wu, P., Luo, X., Wu, H., Zhang, Q., Dai, Y., & Sun, M. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120311 · Cited by 37
Yang, J., Zhang, J., Xing, J., Shi, Z., Han, H., & Li, Q. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s211744 · Cited by 11
Metadata
- Authors
- Wang, M., Liu, H., Li, L., & Cheng, Y.
- Venue
- Nature Communications
- Published
- 2014-01-10
- Volume
- 5
- Issue
- 1
- Pages
- 3053-3053
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W1974242784
- Cited by
- 415
- References
- 1
- FWCI
- 23.24
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.springernature.com/gp/researchers/text-and-data-mining (tdm)
- www.springernature.com/gp/researchers/text-and-data-mining (vor)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.