Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

Cited by (1,002)

Items 201–300 of 1,002

1. The genetic and epigenetic basis of type 2 diabetes and obesity
   Drong, A W, Lindgren, C M, McCarthy, M I · 2012 · Clinical Pharmacology & Therapeutics
2. GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
   Yeda Wu, Graham K. Murray, Enda M. Byrne, Julia Sidorenko, Peter M. Visscher, Naomi R. Wray · 2021 · Nature Communications
3. Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations
   Nora Franceschini, Ervin Ray Fox, Zhaogong Zhang, Todd L. Edwards, Mike A. Nalls, Yun Ju Sung, Bamidele O. Tayo, Yan V. Sun, Omri Gottesman, Adebowale Adeyemo et al. · 2013 · The American Journal of Human Genetics
4. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder
   Liping Hou, Sarah E. Bergen, Nirmala Akula, Jie Song, Christina M. Hultman, Mikael Landén, Mazda Adli, Martin Alda, Raffaella Ardau, Bárbara Arias et al. · 2016 · Human Molecular Genetics
5. Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens
   Morris, John A., Caragine, Christina, Daniloski, Zharko, Domingo, Júlia, Barry, Timothy, Lu, Lu, Davis, Kyrie, Ziosi, Marcello, Glinos, Dafni A., Hao, Stephanie et al. · 2023 · Science
6. Mendelian randomization with fine‐mapped genetic data: Choosing from large numbers of correlated instrumental variables
   Stephen Burgess, Verena Zuber, Elsa Valdés‐Márquez, Benjamin B. Sun, Jemma C. Hopewell · 2017 · Genetic Epidemiology
7. Cerebral small vessel disease genomics and its implications across the lifespan
   Muralidharan Sargurupremraj, Hideaki Suzuki, Xueqiu Jian, Chloé Sarnowski, Tavia E. Evans, Joshua C. Bis, Gudny Eiriksdottir, Saori Sakaue, Natalie Terzikhan, Mohamad Habes et al. · 2020 · Nature Communications
8. Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
   Weiwei Zhang, Tim D. Spector, Panos Deloukas, Jordana T. Bell, Barbara Elizabeth Engelhardt · 2015 · Genome biology
9. Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy
   Krzysztof Kiryluk, Elena Sánchez, Shu‐Feng Zhou, Francesca Zanoni, Lili Liu, Nikol Mladkova, Atlas Khan, Maddalena Marasà, Jun Y. Zhang, Olivia Balderes et al. · 2023 · Nature Genetics
10. Association of rare and common variation in the lipoprotein lipase gene with coronary artery disease
    Khera, Amit V., Won, Hong-Hee, Peloso, Gina M., O’Dushlaine, Colm, Liu, Dajiang, Stitziel, Nathan O., Natarajan, Pradeep, Nomura, Akihiro, Emdin, Connor A., Gupta, Namrata et al. · 2017 · JAMA
11. Meta-analysis of gene-level tests for rare variant association
    Dajiang J. Liu, Gina Marie Peloso, Xiaowei Zhan, Oddgeir L. Holmen, Matthew Zawistowski, Shuang Feng, Majid Nikpay, Paul Livermore Auer, Anuj Goel, He Zhang et al. · 2013 · Nature Genetics
12. High-density genotyping study identifies four new susceptibility loci for atopic dermatitis
    David Ellinghaus, Hansjörg Baurecht, Jorge Esparza-Gordillo, Elke Rodríguez, Anja Matanovic, Ingo Marenholz, Norbert Hübner, Heidi Schaarschmidt, Natalija Novak, Sven Michel et al. · 2013 · Nature Genetics
13. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
    Bogdan Paşaniuc, Noah Zaitlen, Huwenbo Shi, Gaurav Bhatia, Alexander Gusev, Joseph K. Pickrell, Joel N. Hirschhorn, David Peter Strachan, Nick J. Patterson, Alkes L. Price · 2014 · Bioinformatics
14. Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
    Xiangrui Meng, Georgina Navoly, Olga Giannakopoulou, Daniel F. Levey, Dóra Koller, Gita A. Pathak, Nastassja Koen, Kuang Lin, Mark J. Adams, Miguel E. Rentería et al. · 2024 · Nature Genetics
15. GWASdb v2: an update database for human genetic variants identified by genome-wide association studies
    Mulin Jun Li, Zipeng Liu, Panwen Wang, Maria Pik Wong, Matthew R. Nelson, Jean‐Pierre Kocher, Meredith Yeager, Pak Chung Sham, Stephen Jacob Chanock, Zhengyuan Xia et al. · 2015 · Nucleic Acids Research
16. Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis
    Puya Gharahkhani, Rebecca Claire Fitzgerald, Thomas L. Vaughan, Claire Palles, Ines Gockel, Ian P.M. Tomlinson, Matthew F. Buas, Andrea May, Christian Gerges, Mario Anders et al. · 2016 · The Lancet Oncology
17. GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
    Elena López‐Isac, Marialbert Acosta‐Herrera, Martin Kerick, Shervin Assassi, Ansuman T. Satpathy, Jeffrey M. Granja, Maxwell R. Mumbach, Lorenzo Beretta, Carmen Pilar Simeón‐Aznar, Patricia Esmeralda Carreira et al. · 2019 · Nature Communications
18. An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs
    Cordell, Heather J., Fryett, James J., Ueno, Kazuko, Darlay, Rebecca, Aiba, Yoshihiro, Hitomi, Yuki, Kawashima, Minae, Nishida, Nao, Khor, Seik-Soon, Gervais, Olivier et al. · 2021 · Journal of Hepatology
19. Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals
    Hang Zhou, Rachel L. Kember, Joseph D. Deak, Heng Xu, Sylvanus Toikumo, Kai Yuan, Penelope A. Lind, Leila Farajzadeh, Lu Wang, Alexander S. Hatoum et al. · 2023 · Nature Medicine
20. Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits
    Andrew Bakshi, Zhihong Zhu, Anna A. E. Vinkhuyzen, William David Hill, Allan F. McRae, Peter M. Visscher, Jian Yang · 2016 · Scientific Reports
21. Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
    Robin N. Beaumont, Nicole M. Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca Claire Richmond, Lavinia Paternoster et al. · 2018 · Human Molecular Genetics
22. Characterizing rare and low-frequency height-associated variants in the Japanese population
    Masato Akiyama, Kazuyoshi Ishigaki, Saori Sakaue, Yukihide Momozawa, Momoko Horikoshi, Makoto Hirata, Koichi Matsuda, Shiro Ikegawa, Atsushi Takahashi, Masahiro Kanai et al. · 2019 · Nature Communications
23. GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank
    Helena R. R. Wells, Maxim B. Freidin, Fatin N. Zainul Abidin, Antony Payton, Piers Dawes, Kevin James Munro, Cynthia Casson Morton, David R. Moore, Sally J. Dawson, Frances M. K. Williams · 2019 · The American Journal of Human Genetics
24. Genetic associations for two biological age measures point to distinct aging phenotypes
    Chia‐Ling Kuo, Luke C. Pilling, Zuyun Liu, Janice L. Atkins, Morgan E. Levine · 2021 · Aging Cell
25. Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus
    Xianyong Yin, Kwang-Woo Kim, Hiroyuki Suetsugu, So‐Young Bang, Leilei Wen, Masaru Koido, Eunji Ha, Lu Liu, Yuma Sakamoto, Sungsin Jo et al. · 2020 · Annals of the Rheumatic Diseases
26. Genomic prediction of cognitive traits in childhood and adolescence
    Andrea G. Allegrini, Saskia Selzam, Kaili Rimfeld, Sophie von Stumm, Jean‐Baptiste Pingault, Robert J. Plomin · 2019 · Molecular Psychiatry
27. Identification of 12 genetic loci associated with human healthspan
    Zenin, Aleksandr, Tsepilov, Yakov, Sharapov, Sodbo, Getmantsev, Evgeny, Menshikov, L. I., Fedichev, Peter O., Aulchenko, Yurii · 2019 · Communications Biology
28. Widespread signatures of natural selection across human complex traits and functional genomic categories
    Zeng, Jian, Xue, Angli, Jiang, Longda, Lloyd-Jones, Luke R., Wu, Yang, Wang, Huanwei, Zheng, Zhili, Yengo, Loic, Kemper, Kathryn E., Goddard, Michael E. et al. · 2021 · Nature Communications
29. Progress and promise in understanding the genetic basis of common diseases
    Price, Alkes L., Spencer, Chris C. A., Donnelly, Peter · 2015 · Proceedings of the Royal Society B: Biological Sciences
30. Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer
    Yingchang Lu, Sun‐Seog Kweon, Chizu Tanikawa, Wei-Hua Jia, Yong-Bing Xiang, Qiuyin Cai, Chenjie Zeng, Stephanie L. Schmit, Aesun Shin, Keitaro Matsuo et al. · 2018 · Gastroenterology
31. Association mapping in plants in the post-GWAS genomics era
    Pushpendra Kumar Gupta, Pawan L. Kulwal, Vandana Jaiswal · 2019 · Advances in genetics
32. Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
    C. Scott Gallagher, Netta Mäkinen, Holly Ruth Harris, Nilüfer Rahmioğlu, Outi Uimari, James P. Cook, Nina Shigesi, Teresa Cruz Ferreira, Digna R. Velez-Edwards, Todd L. Edwards et al. · 2019 · Nature Communications
33. Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes
    Marios K. Georgakis, Rainer Malik, Dipender Gill, Nora Franceschini, Cathie L. M. Sudlow, Martin Dichgans, Sara Lindström, Lu Wang, Erin N. Smith, William Gordon et al. · 2020 · Circulation Genomic and Precision Medicine
34. Improving genetic prediction by leveraging genetic correlations among human diseases and traits
    Robert M. Maier, Zhihong Zhu, Sang Lee, Maciej Trzaskowski, Douglas M. Ruderfer, Eli A. Stahl, Stephan Ripke, Naomi R. Wray, Jian Yang, Peter M. Visscher et al. · 2018 · Nature Communications
35. Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
    Vasiliki Lagou, Reedik Mägi, Jouke‐Jan Hottenga, Harald Grallert, John R. B. Perry, Nabila Bouatia‐Naji, Letizia Marullo, Denis V. Rybin, Rick Jansen, Josine L. Min et al. · 2021 · Nature Communications
36. Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length
    Chen Li, Svetlana Stoma, Luca Andrea Lotta, Sophie C. Warner, Eva Albrecht, Alessandra Allione, Pascal Arp, Linda Broer, Jessica L. Buxton, Alexessander Couto Alves et al. · 2020 · The American Journal of Human Genetics
37. Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank
    Kim Valette, Zhonglin Li, Valentin Bon-Baret, Arnaud Chignon, Jean‐Christophe Bérubé, Aïda Eslami, Jennifer Lamothe, Nathalie Gaudreault, Philippe Joubert, Ma’en Obeidat et al. · 2021 · Communications Biology
38. Genome‐Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease
    Manuela M. X. Tan, Michael Lawton, Edwin Jabbari, Regina Hertfelder Reynolds, Hirotaka Iwaki, Cornelis Blauwendraat, Sofia Kanavou, Miriam I. Pollard, Leon Hubbard, Naveed Malek et al. · 2020 · Movement Disorders
39. The missing link between genetic association and regulatory function
    Noah J Connally, Sumaiya Nazeen, Daniel Lee, Huwenbo Shi, John A. Stamatoyannopoulos, Sung Chun, Chris J. Cotsapas, Christopher A. Cassa, Shamil R. Sunyaev · 2022 · eLife
40. Bayesian large-scale multiple regression with summary statistics from genome-wide association studies
    Xiang Zhu, Matthew Stephens · 2017 · The Annals of Applied Statistics
41. Within-breed and multi-breed GWAS on imputed whole-genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle
    Marie-Pierre Sanchez, Armelle Govignon-Gion, Pascal Croiseau, Sébastien Fritz, Chris Hozé, Guy Miranda, Patrice Martin, Anne Barbat, Rabia Letaïef, Dominique Rocha et al. · 2017 · Genetics Selection Evolution
42. Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data
    Apostolos Gkatzionis, Stephen Burgess, Paul J. Newcombe · 2022 · Genetic Epidemiology
43. Genetic loci associated with heart rate variability and their effects on cardiac disease risk
    Ilja Maria Nolte, M. Loretto Muñoz, Vinicius Tragante, Azmeraw T. Amare, Rick Jansen, Ahmad Vaez, Benedikt von der Heyde, Christy L. Avery, Joshua C. Bis, Bram Dierckx et al. · 2017 · Nature Communications
44. Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema
    Åsa Johansson, Mathias Rask‐Andersen, Torgny Karlsson, Weronica E. Ek · 2019 · Human Molecular Genetics
45. Explaining additional genetic variation in complex traits
    Matthew R. Robinson, Naomi R. Wray, Peter M. Visscher · 2014 · Trends in Genetics
46. Genome-Wide Association Studies
    Abbas Dehghan · 2018 · Methods in molecular biology
47. Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease
    Winkler, Thomas W., Grassmann, Felix, Brandl, Caroline, Kiel, Christina, Günther, Felix, Strunz, Tobias, Weidner, Lorraine, Zimmermann, Martina E., Korb, Christina A., Poplawski, Alicia et al. · 2020 · BMC Medical Genomics
48. Genomic insights into the causes of type 2 diabetes
    Claudia Langenberg, Luca Andrea Lotta · 2018 · The Lancet
49. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels
    Cassandra Nichole Spracklen, Peng Chen, Young Jin Kim, Xu Wang, Hui Cai, Shengxu Li, Jirong Long, Ying Wu, Ya Xing Wang, Fumihiko Takeuchi et al. · 2017 · Human Molecular Genetics
50. Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets
    Carla Márquez‐Luna, Steven Gazal, Po‐Ru Loh, Samuel Sungil Kim, Nicholas A. Furlotte, Adam Auton, Michelle Agee, Babak Alipanahi, Robert K. Bell, Katarzyna Bryc et al. · 2021 · Nature Communications
51. Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese
    Lubitz, Steven A., Lunetta, Kathryn L., Lin, Honghuang, Arking, Dan E., Trompet, Stella, Li, Guo, Krijthe, Bouwe P., Chasman, Daniel I., Barnard, John, Kleber, Marcus E. et al. · 2014 · Journal of the American College of Cardiology
52. Exome-wide association study on alanine aminotransferase identifies sequence variants in the GPAM and APOE associated with fatty liver disease
    Jamialahmadi, Oveis, Mancina, Rosellina Margherita, Ciociola, Ester, Tavaglione, Federica, Luukkonen, Panu K., Baselli, Guido, Malvestiti, Francesco, Thuillier, Dorothée, Raverdy, Violeta, Männistö, Ville et al. · 2021 · Gastroenterology
53. Assessing the Causal Relationship of Maternal Height on Birth Size and Gestational Age at Birth: A Mendelian Randomization Analysis
    Ge Zhang, Jonas Bačelis, Candice Lengyel, Kari Teramo, Mikko Hallman, Øyvind Helgeland, Stefan Johansson, Ronny Myhre, Verena Sengpiel, Pål R. Njølstad et al. · 2015 · PLoS Medicine
54. Defining the role of common variation in the genomic and biological architecture of adult human height
    The Electronic Medical Records and Genomics (eMERGE) Consortium, Wood, Andrew R, The MIGen Consortium, The PAGE Consortium, The LifeLines Cohort Study, Esko, Tonu, Yang, Jian, Vedantam, Sailaja, Pers, Tune H, Gustafsson, Stefan et al. · 2014 · Nature Genetics
55. Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
    Andrew P. Morris, Thu H Le, Hao Wu, Artur Akbarov, Peter J. van der Most, Gibran Hemani, George Davey Smith, Anubha Mahajan, Kyle J. Gaulton, Girish N. Nadkarni et al. · 2018 · Nature Communications
56. Prioritizing Parkinson’s disease genes using population-scale transcriptomic data
    Li, Yang I., Wong, Garrett, Humphrey, Jack, Raj, Towfique · 2019 · Nature Communications
57. Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence
    Rohan H. C. Palmer, Leslie Ann D. Brick, Nicole R. Nugent, L. Cinnamon Bidwell, John E. McGeary, Valerie S. Knopik, Matthew C. Keller · 2014 · Addiction
58. Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease
    Oveis Jamialahmadi, Antonio De Vincentis, Federica Tavaglione, Francesco Malvestiti, Ruifang Li‐Gao, Rosellina Margherita Mancina, Marcus Alvarez, Kyla Z. Gelev, Samantha Maurotti, Umberto Vespasiani Gentilucci et al. · 2024 · Nature Medicine
59. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation
    María Soler Artigas, Louise V. Wain, Suzanne Miller, Abdul Kader Kheirallah, Jennifer E. Huffman, Ιωάννα Ντάλλα, Nick R. G. Shrine, Ma’en Obeidat, Holly Trochet, Wendy L. McArdle et al. · 2015 · Nature Communications
60. Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
    Erik L. Bao, Satish Kumar Nandakumar, Xiaotian Liao, Alexander G. Bick, Juha Karjalainen, Marcin Tabaka, Olga I. Gan, Aki Samuli Havulinna, Tuomo Kiiskinen, Caleb A. Lareau et al. · 2020 · Nature
61. Metagenomic Predictions: From Microbiome to Complex Health and Environmental Phenotypes in Humans and Cattle
    Elizabeth M. Ross, Peter J. Moate, Leah C. Marett, Ben Cocks, Ben J. Hayes · 2013 · PLoS ONE
62. Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases
    Lucija Klarić, Yakov A. Tsepilov, Chloë M. Stanton, Massimo Mangino, Timo Tõnis Sikka, Tõnu Esko, Eugene Pakhomov, Perttu P. Salo, Joris Deelen, Stuart J. McGurnaghan et al. · 2020 · Science Advances
63. Genome-wide association analysis identifies six new loci associated with forced vital capacity
    Daan W. Loth, María Soler Artigas, Sina A. Gharib, Louise V. Wain, Nora Franceschini, Beate Koch, Tess D. Pottinger, Albert V. Smith, Qing Duan, Christopher J. Oldmeadow et al. · 2014 · Nature Genetics
64. Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci
    Joseph D. Deak, Hang Zhou, Marco Galimberti, Daniel F. Levey, Frank R. Wendt, Sandra Sanchez‐Roige, Alexander S. Hatoum, Emma C. Johnson, Yaira Z. Nuñez, Ditte Demontis et al. · 2022 · Molecular Psychiatry
65. Genome-wide fine-mapping identifies pleiotropic and functional variants that predict many traits across global cattle populations
    Ruidong Xiang, Iona M. MacLeod, Hans D. Daetwyler, G. de Jong, Erin S. O’Connor, C. Schrooten, Amanda Jane Chamberlain, Michael Edward Goddard · 2021 · Nature Communications
66. Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
    Natalia Pervjakova, Gunn-Helen Moen, Maria Carolina Borges, Teresa Cruz Ferreira, James P. Cook, Catherine Allard, Robin N. Beaumont, Mickaël Canouil, Gad Hatem, Anni Heiskala et al. · 2022 · Human Molecular Genetics
67. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
    Ashley Budu‐Aggrey, Anna Kilanowski, Maria Sobczyk, Suyash Shringarpure, Ruth E. Mitchell, Kadri Reis, Anu Reigo, Reedik Mägi, Mari Nelis, Nao Tanaka et al. · 2023 · Nature Communications
68. Assessing the causal association of glycine with risk of cardio-metabolic diseases
    Laura B. L. Wittemans, Luca Andrea Lotta, Clare Oliver‐Williams, Isobel D. Stewart, Praveen Surendran, Savita Karthikeyan, Felix R. Day, Albert Koulman, Fumiaki Imamura, Lingyao Zeng et al. · 2019 · Nature Communications
69. Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
    Marie‐Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E. Evans, Aniket Mishra, Ami Tsuchida, Gennady V. Roshchupkin, Takahiro Konuma, David‐Alexandre Trégouët, Jose Rafael Romero et al. · 2023 · Nature Medicine
70. GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer
    Zhou, Wei, Brumpton, Ben, Kabil, Omer, Gudmundsson, Julius, Thorleifsson, Gudmar, Weinstock, Josh, Zawistowski, Matthew, Nielsen, Jonas B., Chaker, Layal, Medici, Marco et al. · 2020 · Nature Communications
71. metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis
    Anna Cichońska, Juho Rousu, Pekka Marttinen, Antti J. Kangas, Pasi Soininen, Terho J. Lehtimäki, Olli Tuomas Raitakari, Marjo‐Riitta Järvelin, Veikko V Salomaa, Mika Ala‐Korpela et al. · 2016 · Bioinformatics
72. Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution
    Arkan Abadi, Akram Alyass, Sébastien Robiou-du-Pont, Benjamin M. Bolker, Pardeep Singh, Viswanathan Mohan, Rafael Díaz, James C. Engert, Salim Yusuf, Hertzel C. Gerstein et al. · 2017 · The American Journal of Human Genetics
73. Genomic prediction using preselected DNA variants from a GWAS with whole-genome sequence data in Holstein–Friesian cattle
    Roel F. Veerkamp, A.C. Bouwman, C. Schrooten, M.P.L. Calus · 2016 · Genetics Selection Evolution
74. A unified framework for variance component estimation with summary statistics in genome-wide association studies
    Xiang Zhou · 2017 · The Annals of Applied Statistics
75. A Lasso multi-marker mixed model for association mapping with population structure correction
    Barbara Rakitsch, Christoph Lippert, Oliver Stegle, Karsten Michael Borgwardt · 2012 · Bioinformatics
76. 52 Genetic Loci Influencing Myocardial Mass
    Pim van der Harst, Jessica van Setten, Niek Verweij, Georg Vogler, Lude Franke, Matthew T. Maurano, Xinchen Wang, Irene Mateo Leach, Mark Eijgelsheim, Nona Sotoodehnia et al. · 2016 · Journal of the American College of Cardiology
77. Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis
    Richard J. Allen, Amy Stockwell, Justin M. Oldham, Beatriz Guillén‐Guío, David A. Schwartz, Toby M. Maher, Carlos Flores, Imre Noth, Brian L. Yaspan, Gisli R. Jenkins et al. · 2022 · Thorax
78. Quantifying Missing Heritability at Known GWAS Loci
    Alexander Gusev, Gaurav Bhatia, Noah Zaitlen, Bjarni Jóhann Vilhjálmsson, Dorothée Diogo, Eli A. Stahl, Peter K. Gregersen, Jane Worthington, Lars Klareskog, Soumya Raychaudhuri et al. · 2013 · PLoS Genetics
79. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
    Yap, Chloe X., Sidorenko, Julia, Wu, Yang, Kemper, Kathryn E., Yang, Jian, Wray, Naomi R., Robinson, Matthew R., Visscher, Peter M. · 2018 · Nature Communications
80. The Power of Meta-Analysis in Genome-Wide Association Studies
    Orestis A. Panagiotou, Cristen J. Willer, Joel N. Hirschhorn, John P. A. Ioannidis · 2013 · Annual Review of Genomics and Human Genetics
81. Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations
    Jingjing Liang, Thu H. Le, Digna R. Velez Edwards, Bamidele O. Tayo, Kyle J. Gaulton, Jennifer A. Smith, Yingchang Lu, Richard A. Jensen, Guanjie Chen, Lisa R. Yanek et al. · 2017 · PLoS Genetics
82. Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
    Maryam Kavousi, Maxime M. Bos, Hanna J. Barnes, Christian Lacks Lino Cardenas, Doris Wong, Haojie Lu, Chani J. Hodonsky, Lennart P. L. Landsmeer, Adam W. Turner, Minjung Kho et al. · 2023 · Nature Genetics
83. Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
    Manuel A. R. Ferreira, Eric R. Gamazon, Fares Al‐Ejeh, Kristiina Aittomäki, Irene Louise Andrulis, Hoda Anton‐Culver, Aðalgeir Arason, Volker Arndt, Kristan J. Aronson, Banu Arun et al. · 2019 · Nature Communications
84. Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon
    Marion Sinclair‐Waters, Jørgen Ødegård, Sven Arild Korsvoll, Thomas Moen, Sigbjørn Lien, Craig Robert Primmer, Nicola J. Barson · 2020 · Genetics Selection Evolution
85. C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: A genome‐wide meta‐analysis
    Frank P. Diekstra, Vivianna M. Van Deerlin, John Cornelis Van Swieten, Ammar Al‐Chalabi, Albert Christian Ludolph, Jochen Hans Weishaupt, Orla M. Hardiman, John E. Landers, Robert H. Brown, Michael A. van Es et al. · 2014 · Annals of Neurology
86. Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics
    Bovijn, Jonas, Krebs, Kristi, Chen, Chia-Yen, Boxall, Ruth, Censin, Jenny C., Ferreira, Teresa, Pulit, Sara L., Glastonbury, Craig A., Laber, Samantha, Millwood, Iona Y. et al. · 2020 · Science Translational Medicine
87. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study
    Daniel J. Gottlieb, Karin Hek, T-h Chen, Nathaniel F. Watson, Guðný Eiríksdóttir, Enda M. Byrne, Marilyn C. Cornelis, Simon C. Warby, Stefania Bandinelli, Lynn F. Cherkas et al. · 2014 · Molecular Psychiatry
88. Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium
    Maggie C.Y. Ng, Mariaelisa Graff, Yingchang Lu, Anne E. Justice, Poorva Mudgal, Ching‐Ti Liu, Kristin L. Young, Lisa R. Yanek, Mary Furlan Feitosa, Mary K. Wojczynski et al. · 2017 · PLoS Genetics
89. Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
    Bryan C. Quach, Michael A. Bray, Nathan Gaddis, Mengzhen Liu, Teemu Palviainen, Camelia C. Minică, Stephanie M. Zellers, Richard Sherva, Fazil Alıev, Michael Nothnagel et al. · 2020 · Nature Communications
90. Genetic Architecture of Feeding Behavior and Feed Efficiency in a Duroc Pig Population
    Rongrong Ding, Ming Jun Yang, Xingwang Wang, Jianping Quan, Zhanwei Zhuang, Shenping Zhou, Shaoyun Li, Zheng Xu, Enqin Zheng, Gengyuan Cai et al. · 2018 · Frontiers in Genetics
91. Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study
    Yu Chen, Hao, Dina, Christian, Small, Aeron M, Shaffer, Christian M, Levinson, Rebecca T, Helgadóttir, Anna, Capoulade, Romain, Munter, Hans Markus, Martinsson, Andreas, Cairns, Benjamin J et al. · 2023 · European Heart Journal
92. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function
    Mathias Gorski, Peter J. van der Most, Alexander Teumer, Audrey Y. Chu, Man Li, Vladan Mijatovic, Ilja Maria Nolte, Massimiliano Cocca, Daniel Taliun, Felicia Gomez et al. · 2017 · Scientific Reports
93. Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases
    Marialbert Acosta‐Herrera, Martin Kerick, David González‐Serna, Cisca Wijmenga, André Franke, Peter K. Gregersen, Leonid Padyukov, Jane Worthington, Timothy James Vyse, Marta Eugenia Alarcón-Riquelme et al. · 2018 · Annals of the Rheumatic Diseases
94. Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images
    Hannah Currant, Pirro G. Hysi, Tomas W. Fitzgerald, Puya Gharahkhani, Pieter W. M. Bonnemaijer, Anne Senabouth, Alex William Hewitt, Denize Atan, Tin Aung, Jason Charng et al. · 2021 · PLoS Genetics
95. Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer
    Jinyoung Byun, Younghun Han, Yafang Li, Jun Xia, Erping Long, Jiyeon Choi, Xiangjun Xiao, Meng Zhu, Wen Zhou, Ryan Sun et al. · 2022 · Nature Genetics
96. Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis
    Brian D. Hobbs, Rachel K. Putman, Tetsuro Araki, Mizuki Nishino, Gunnar Guðmundsson, Vilmundur G. Gudnason, Guðný Eiríksdóttir, Nuno R. Zilhäo, Josée Dupuis, Hanfei Xu et al. · 2019 · American Journal of Respiratory and Critical Care Medicine
97. Identifying multiple causative genes at a single GWAS locus
    Michael J. Flister, Shirng‐Wern Tsaih, Caitlin Claire O'Meara, Bradley T. Endres, Matthew J. Hoffman, Aron M. Geurts, Melinda R. Dwinell, Jozef Lazar, Howard J. Jacob, Carol Moreno · 2013 · Genome Research
98. Gene—Environment Interactions in Major Depressive Disorder
    Torsten Klengel, Elisabeth B. Binder · 2013 · The Canadian Journal of Psychiatry
99. Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease
    Western, Daniel, Timsina, Jigyasha, Wang, Lihua, Wang, Ciyang, Yang, Chengran, Phillips, Bridget, Wang, Yueyao, Liu, Menghan, Ali, Muhammad, Beric, Aleksandra et al. · 2024 · Nature Genetics
100. Replicability and Robustness of Genome-Wide-Association Studies for Behavioral Traits
     Rietveld, Cornelius A., Conley, Dalton, Eriksson, Nicholas, Esko, Tõnu, Medland, Sarah E., Vinkhuyzen, Anna A. E., Yang, Jian, Boardman, Jason D., Chabris, Christopher F., Dawes, Christopher T. et al. · 2014 · Psychological Science