Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

Cited by (1,002)

Items 101–200 of 1,002

1. Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
   Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili et al. · 2018 · Nature Communications
2. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
   Symen Ligthart, Ahmad Vaez, Urmo Võsa, Maria G. Stathopoulou, Paul S. de Vries, Bram P. Prins, Peter J. van der Most, Toshiko Tanaka, Elnaz Naderi, Lynda M. Rose et al. · 2018 · The American Journal of Human Genetics
3. An integrated framework for local genetic correlation analysis
   Josefin Werme, Sophie van der Sluis, Daniëlle Posthuma, Christiaan de Leeuw · 2022 · Nature Genetics
4. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
   Georg Ehret, Teresa Cruz Ferreira, Daniel I. Chasman, Anne Jackson, Ellen M. Schmidt, Toby Johnson, Guðmar Þorleifsson, Jian’an Luan, Louise A Donnelly, Stavroula Kanoni et al. · 2016 · Nature Genetics
5. Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility
   Raj, Towfique, Li, Yang I., Wong, Garrett, Humphrey, Jack, Wang, Minghui, Ramdhani, Satesh, Wang, Ying-Chih, Ng, Bernard, Gupta, Ishaan, Haroutunian, Vahram et al. · 2018 · Nature Genetics
6. Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration
   Joana A. Revez, Tian Lin, Zhen Qiao, Angli Xue, Yan Holtz, Zhihong Zhu, Jian Zeng, Huanwei Wang, Julia Sidorenko, Kathryn E. Kemper et al. · 2020 · Nature Communications
7. GWAS identifies 14 loci for device-measured physical activity and sleep duration
   Doherty, Aiden, Smith-Byrne, Karl, Ferreira, Teresa, Holmes, Michael V., Holmes, Chris, Pulit, Sara L., Lindgren, Cecilia M. · 2018 · Nature Communications
8. Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
   Grundberg, Elin, Meduri, Eshwar, Sandling, Johanna K., Hedman, Åsa K., Keildson, Sarah, Buil, Alfonso, Busche, Stephan, Yuan, Wei, Nisbet, James, Sekowska, Magdalena et al. · 2013 · The American Journal of Human Genetics
9. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score
   Desikan, Rahul S., Fan, Chun Chieh, Wang, Yunpeng, Schork, Andrew J., Cabral, Howard J., Cupples, L. Adrienne, Thompson, Wesley K., Besser, Lilah, Kukull, Walter A., Holland, Dominic et al. · 2017 · PLoS Medicine
10. Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
    Louise V. Wain, Nick R. G. Shrine, Suzanne Miller, Victoria E. Jackson, Ioanna Ntalla, María Soler Artigas, Charlotte K. Billington, Abdul Kader Kheirallah, Richard J. Allen, James P. Cook et al. · 2015 · The Lancet Respiratory Medicine
11. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
    COPDGene Investigators, Brian D. Hobbs, ECLIPSE Investigators, LifeLines Investigators, International COPD Genetics Network Investigators, UK BiLEVE Investigators, Kim de Jong, Maxime Lamontagne, Yohan Bossé, Nick R. G. Shrine et al. · 2017 · Nature Genetics
12. Biological and clinical insights from genetics of insomnia symptoms
    HUNT All In Sleep, Jacqueline M. Lane, Samuel E. Jones, Hassan S. Dashti, Andrew R. Wood, Krishna G. Aragam, Vincent T. van Hees, Linn Beate Strand, Bendik Slagsvold Winsvold, Heming Wang et al. · 2019 · Nature Genetics
13. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
    Kyle J. Gaulton, Teresa Cruz Ferreira, Yeji Lee, Anne Raimondo, Reedik Mägi, Michael E. Reschen, Anubha Mahajan, Adam E. Locke, Nigel William Rayner, Neil Robertson et al. · 2015 · Nature Genetics
14. Association Between Low-Density Lipoprotein Cholesterol–Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis
    Lotta, Luca A., Sharp, Stephen J., Burgess, Stephen, Perry, John R. B., Stewart, Isobel D., Willems, Sara M., Luan, Jian’an, Ardanaz, Eva, Arriola, Larraitz, Balkau, Beverley et al. · 2016 · JAMA
15. Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies
    Zhang, Jingning, Dutta, Diptavo, Köttgen, Anna, Tin, Adrienne, Schlosser, Pascal, Grams, Morgan E., Harvey, Benjamin, CKDGen Consortium, Yu, Bing, Boerwinkle, Eric et al. · 2022 · Nature Genetics
16. Genetic Associations with Gestational Duration and Spontaneous Preterm Birth
    Ge Zhang, Bjarke Feenstra, Jonas Bačelis, Xueping Liu, Lisa M. Muglia, Julius Juodakis, Daniel E. Miller, Nadia K. Litterman, Panpan Jiang, Laura E. Russell et al. · 2017 · New England Journal of Medicine
17. Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
    Xia Jiang, Paul F. O’Reilly, Hugues Aschard, Yi‐Hsiang Hsu, John Brent Richards, Josée Dupuis, Erik Ingelsson, David Karasik, Stefan Pilz, Diane J. Berry et al. · 2018 · Nature Communications
18. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
    Phuwanat Sakornsakolpat, Dmitry Prokopenko, Maxime Lamontagne, Nicola F. Reeve, Anna L. Guyatt, Victoria E. Jackson, Nick R. G. Shrine, Dandi Qiao, Traci M. Bartz, Deog Kyeom Kim et al. · 2019 · Nature Genetics
19. Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis
    Kar, Siddhartha P., Quiros, Pedro M., Gu, Muxin, Jiang, Tao, Mitchell, Jonathan, Langdon, Ryan, Iyer, Vivek, Barcena, Clea, Vijayabaskar, M. S., Fabre, Margarete A. et al. · 2022 · Nature Genetics
20. Genetics of Coronary Artery Disease
    Ruth McPherson, Anne Tybjærg‐Hansen · 2016 · Circulation Research
21. Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data
    Dmitry Shungin, Simon J. Haworth, Kimon Divaris, Cary S. Agler, Yoichiro Kamatani, Myoung Keun Lee, Kelsey E. Grinde, George Hindy, Viivi Alaraudanjoki, Paula Pesonen et al. · 2019 · Nature Communications
22. Functionally informed fine-mapping and polygenic localization of complex trait heritability
    Weissbrod, Omer, Hormozdiari, Farhad, Benner, Christian, Cui, Ran, Ulirsch, Jacob, Gazal, Steven, Schoech, Armin P., van de Geijn, Bryce, Reshef, Yakir, Márquez-Luna, Carla et al. · 2020 · Nature Genetics
23. Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies
    Nilanjan Chatterjee, Bill Wheeler, Joshua Neil Sampson, Patricia A. Hartge, Stephen Jacob Chanock, Ju-Hyun Park · 2013 · Nature Genetics
24. Integrating predicted transcriptome from multiple tissues improves association detection
    Alvaro Barbeira, Milton Pividori, Jiamao Zheng, Heather E. Wheeler, Dan L. Nicolae, Hae Kyung Im · 2019 · PLoS Genetics
25. Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
    Hang Zhou, Julia Sealock, Sandra Sanchez‐Roige, Toni‐Kim Clarke, Daniel F. Levey, Zhongshan Cheng, Boyang Li, Renato A Polimanti, Rachel L. Kember, Rachel Vickers‐Smith et al. · 2020 · Nature Neuroscience
26. Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors
    Beatrice S. Melin, Jill S. Barnholtz‐Sloan, Margaret Wrensch, Christoffer Johansen, Dora Il’yasova, Ben Kinnersley, Quinn T. Ostrom, Karim Labrèche, Yanwen Chen, Georgina Armstrong et al. · 2017 · Nature Genetics
27. The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers
    Christopher Ian Amos, Joe Dennis, Zhaoming Wang, Jinyoung Byun, Fredrick R. Schumacher, Simon A. Gayther, Graham Casey, David J. Hunter, Thomas A. Sellers, Stephen B. Gruber et al. · 2016 · Cancer Epidemiology Biomarkers & Prevention
28. Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism
    Sapkota, Yadav, Steinthorsdottir, Valgerdur, Morris, Andrew P., Fassbender, Amelie, Rahmioglu, Nilufer, De Vivo, Immaculata, Buring, Julie E., Zhang, Futao, Edwards, Todd L., Jones, Sarah et al. · 2017 · Nature Communications
29. Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
    Carolina Medina‐Gómez, John P. Kemp, Katerina Trajanoska, Jian’an Luan, Alessandra Chesi, Tarunveer S. Ahluwalia, Dennis Owen Mook-Kanamori, Annelies C. Ham, Fernando Pires Hartwig, Daniel S. Evans et al. · 2018 · The American Journal of Human Genetics
30. Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma
    Anthony P. Khawaja, Jessica N. Cooke Bailey, Nicholas J. Wareham, Robert A. Scott, Mark J. Simcoe, Robert P. Igo, Yeunjoo E. Song, Robert Wojciechowski, Ching‐Yu Cheng, Peng Tee Khaw et al. · 2018 · Nature Genetics
31. Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
    Karlsson Linnér, Richard, Mallard, Travis T., Barr, Peter B., Sanchez-Roige, Sandra, Madole, James W., Driver, Morgan N., Poore, Holly E., de Vlaming, Ronald, Grotzinger, Andrew D., Tielbeek, Jorim J. et al. · 2021 · Nature Neuroscience
32. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
    Ingrid Elisabeth Christophersen, Michiel Rienstra, Carolina Roselli, Xiaoyan Yin, Bastiaan Geelhoed, John Barnard, Honghuang Lin, Dan E. Arking, Albert V. Smith, Christine M. Albert et al. · 2017 · Nature Genetics
33. A large-scale genome-wide association study meta-analysis of cannabis use disorder
    Emma C. Johnson, Ditte Demontis, Thorgeir Elís Thorgeirsson, Raymond Kenney Walters, Renato A Polimanti, Alexander Samir Hatoum, Sandra Sanchez‐Roige, Sarah E. Paul, Frank R. Wendt, Toni-Kim Clarke et al. · 2020 · The Lancet Psychiatry
34. Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression
    Jamie E. Craig, Xikun Han, Ayub Qassim, Mark Hassall, Jessica N. Cooke Bailey, Tyler G. Kinzy, Anthony P. Khawaja, Jiyuan An, Henry N. Marshall, Puya Gharahkhani et al. · 2020 · Nature Genetics
35. Transethnic Genetic-Correlation Estimates from Summary Statistics
    Brown, Brielin C., Ye, Chun Jimmie, Price, Alkes L., Zaitlen, Noah · 2016 · The American Journal of Human Genetics
36. Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms
    Cornelis Blauwendraat, Karl Heilbron, Costanza Ludovica Vallerga, Sara Bandrés‐Ciga, Rainer von Coelln, Lasse Pihlstrøm, Javier Simón‐Sánchez, Claudia Schulte, Manu Sharma, Lynne Krohn et al. · 2019 · Movement Disorders
37. Genetic predisposition to mosaic Y chromosome loss in blood
    Deborah J. Thompson, The Kidney Cancer GWAS Meta-Analysis Project, Giulio Genovese, Jonatan Halvardson, Jacob C. Ulirsch, Daniel J. Wright, Chikashi Terao, Olafur B. Davidsson, Felix R. Day, Patrick Sulem et al. · 2019 · Nature
38. Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity
    Andrew Robert Harper, Anuj Goel, Christopher Grace, Kate L. Thomson, Steffen Erhard Petersen, Xiao Hua Xu, Adam Waring, Elizabeth Ormondroyd, Christopher M. Kramer, Carolyn Yung Ho et al. · 2021 · Nature Genetics
39. Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors
    HUNT All-In Stroke, Mark K. Bakker, China Kadoorie Biobank Collaborative Group, The ICAN Study Group, CADISP Group, Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study investigators, Rick A. A. van der Spek, Wouter van Rheenen, Sandrine Morel, Romain Bourcier et al. · 2020 · Nature Genetics
40. Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia
    Pirro G. Hysi, Hélène Choquet, Anthony P. Khawaja, Robert Wojciechowski, Milly S. Tedja, Jie Yin, Mark J. Simcoe, Karina Patasova, Omar A. Mahroo, Khanh K. Thai et al. · 2020 · Nature Genetics
41. Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses
    Alison R. Barton, Maxwell A. Sherman, Ronen E. Mukamel, Po‐Ru Loh · 2021 · Nature Genetics
42. Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
    Mariaelisa Graff, Robert A. Scott, Anne E. Justice, Kristin L. Young, Mary Furlan Feitosa, Llilda Barata, Thomas W. Winkler, Audrey Y. Chu, Anubha Mahajan, David Hadley et al. · 2017 · PLoS Genetics
43. Whole-genome sequencing reveals host factors underlying critical COVID-19
    Athanasios Kousathanas, Erola Pairo‐Castineira, Konrad Rawlik, Alex Stuckey, Christopher A. Odhams, Susan Walker, Clark D Russell, Tomas Malinauskas, Yang Wu, Jonathan Edward Millar et al. · 2022 · Nature
44. Genetic evidence of assortative mating in humans
    Robinson, Matthew R., Kleinman, Aaron, Graff, Mariaelisa, Vinkhuyzen, Anna A. E., Couper, David, Miller, Michael B., Peyrot, Wouter J., Abdellaoui, Abdel, Zietsch, Brendan P., Nolte, Ilja M. et al. · 2017 · Nature Human Behaviour
45. Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
    David Lamparter, Daniel Marbach, Rico Rueedi, Zoltán Kutalik, Sven Bergmann · 2016 · PLoS Computational Biology
46. Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits.
    Porcu, Eleonora, Rüeger, Sina, Lepik, Kaido, eQTLGen Consortium, Agbessi, Mawussé, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Arindrarto, Wibowo, Awadalla, Philip et al. · 2019 · Nature Communications
47. Statistical methods for Mendelian randomization in genome-wide association studies: A review
    Frederick J. Boehm, Xiang Zhou · 2022 · Computational and Structural Biotechnology Journal
48. A genome‐wide association study of the frailty index highlights brain pathways in ageing
    Janice L. Atkins, Juulia Jylhävä, Nancy L. Pedersen, Patrik K. E. Magnusson, Yi Lu, Yunzhang Wang, Sara Hägg, David R. Melzer, Dylan M. Williams, Luke C. Pilling · 2021 · Aging Cell
49. Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
    Tsaprouni, Loukia G, Yang, Tsun-Po, Bell, Jordana, Dick, Katherine J, Kanoni, Stavroula, Nisbet, James, Viñuela, Ana, Grundberg, Elin, Nelson, Christopher P, Meduri, Eshwar et al. · 2014 · Epigenetics
50. Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
    Moss, Davina J Hensman, Pardiñas, Antonio F, Langbehn, Douglas, Lo, Kitty, Leavitt, Blair R, Roos, Raymund, Durr, Alexandra, Mead, Simon, Coleman, A, Santos, R Dar et al. · 2017 · The Lancet Neurology
51. Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct
    Manuel A. R. Ferreira, Riddhima Mathur, Judith M. Vonk, Agnieszka Szwajda, Ben Michael Brumpton, Raquel Granell, Bronwyn K. Brew, Vilhelmina Ullemar, Yi Lu, Yunxuan Jiang et al. · 2019 · The American Journal of Human Genetics
52. Common and rare variant associations with clonal haematopoiesis phenotypes
    Kessler, Michael D., Damask, Amy, O’Keeffe, Sean, Banerjee, Nilanjana, Li, Dadong, Watanabe, Kyoko, Marketta, Anthony, Van Meter, Michael, Semrau, Stefan, Horowitz, Julie et al. · 2022 · Nature
53. Seventy-five genetic loci influencing the human red blood cell
    Pim van der Harst, Weihua Zhang, Irene Mateo Leach, Augusto Rendon, Niek Verweij, Joban Sehmi, Dirk S. Paul, Ulrich Elling, Hooman Allayee, Xinzhong Li et al. · 2012 · Nature
54. Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
    Yi Lu, Véronique Vitart, Kathryn P. Burdon, Chiea Chuen Khor, Yelena Bykhovskaya, Alireza Mirshahi, Alex William Hewitt, Demelza Koehn, Pirro G. Hysi, Wishal D. Ramdas et al. · 2013 · Nature Genetics
55. Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
    CARDIoGRAMplusC4D, Joanna M. M. Howson, EPIC-CVD, Wei Zhao, Daniel R. Barnes, Weang-Kee Ho, Robin Young, Dirk S. Paul, Lindsay L. Waite, Daniel F. Freitag et al. · 2017 · Nature Genetics
56. Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals
    Kira J. Stanzick, Yong Li, Pascal Schlosser, Mathias Gorski, Matthias Wuttke, Laurent F. Thomas, Humaira Rasheed, Bryce X. Rowan, Sarah E. Graham, Brett R. Vanderweff et al. · 2021 · Nature Communications
57. Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
    Marcel den Hoed, Mark Eijgelsheim, Tõnu Esko, Bianca J.J.M. Brundel, David S. Peal, David M. Evans, Ilja Maria Nolte, Ayellet V. Segrè, Hilma Hólm, Robert E. Handsaker et al. · 2013 · Nature Genetics
58. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
    Daniel L. McCartney, Josine L. Min, Rebecca Claire Richmond, Ake Tzu-Hui Lu, Maria Sobczyk, Gail Davies, Linda Broer, Xiuqing Guo, Ayoung Jeong, Jeesun Jung et al. · 2021 · Genome biology
59. Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies
    Mark J. Adams, Fabian Streit, Xiangrui Meng, Swapnil Awasthi, Brett N. Adey, Karmel W. Choi, V. Kartik Chundru, Jonathan R. I. Coleman, Bart Ferwerda, Jerome C. Foo et al. · 2025 · Cell
60. Identification of nine new susceptibility loci for endometrial cancer
    Tracy A. O’Mara, Dylan M. Glubb, Frédéric C. Amant, Daniela Annibali, Katie A. Ashton, John Attia, Paul Livermore Auer, Matthias W. Beckmann, Amanda Black, Manjeet K. Bolla et al. · 2018 · Nature Communications
61. Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
    Understanding Society Scientific Group, Louise V. Wain, Nick R. G. Shrine, María Soler Artigas, Abdullah Mesut Erzurumluoglu, Boris Noyvert, Lara Bossini‐Castillo, Ma’en Obeidat, Amanda P. Henry, Michael A. Portelli et al. · 2017 · Nature Genetics
62. Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts
    Sara R. Rashkin, Rebecca E. Graff, Linda Kachuri, Khanh K. Thai, Stacey Alexeeff, Maruta A. Blatchins, Taylor B. Cavazos, Douglas A. Corley, Nima C. Emami, Joshua Hoffman et al. · 2020 · Nature Communications
63. Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits
    Zhang, Yan, Qi, Guanghao, Park, Ju-Hyun, Chatterjee, Nilanjan · 2018 · Nature Genetics
64. A genome-wide association study of serum proteins reveals shared loci with common diseases
    Alexander Guðjónsson, Valborg Guðmundsdóttir, Gisli Thor Axelsson, Elias Freyr Gudmundsson, Brynjolfur G. Jonsson, Lenore J. Launer, John R. Lamb, Lori L. Jennings, Thor Aspelund, Valur Emilsson et al. · 2022 · Nature Communications
65. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
    Marilyn C. Cornelis, Enda M. Byrne, Tõnu Esko, Mike A. Nalls, Andrea Ganna, Nina P. Paynter, Keri L. Monda, Najaf Amin, Krista Fischer, Frida Renström et al. · 2014 · Molecular Psychiatry
66. Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution
    Reedik Mägi, Momoko Horikoshi, Tamar Sofer, Anubha Mahajan, Hidetoshi Kitajima, Nora Franceschini, Mark I. McCarthy, Andrew P. Morris · 2017 · Human Molecular Genetics
67. Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning
    Yi Liu, Nicolas Basty, Brandon J. Whitcher, Jimmy David Bell, Elena P. Sorokin, Nick van Bruggen, Elizabeth Louise Thomas, Madeleine Cule · 2021 · eLife
68. GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
    Linda Broer, Aron S. Buchman, Joris Deelen, Daniel S. Evans, Jessica D. Faul, Kathryn L. Lunetta, Paola Sebastiani B, Jennifer A. Smith, Albert V. Smith, Toshiko Tanaka et al. · 2014 · The Journals of Gerontology Series A
69. Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
    Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung‐Jin Lee, Adam S. Butterworth, Joanna M. M. Howson, Themistocles L. Assimes, Rajiv Chowdhury, Marju Orho‐Melander, Scott M. Damrauer et al. · 2017 · Nature Genetics
70. Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits
    Nicholas Mancuso, Huwenbo Shi, Pagé C. Goddard, Gleb Kichaev, Alexander Gusev, Bogdan Paşaniuc · 2017 · The American Journal of Human Genetics
71. Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization
    Xiaoquan Wen, Roger Piqué-Regi, Francesca Luca · 2017 · PLoS Genetics
72. Variants in the fetal genome near FLT1 are associated with risk of preeclampsia
    Ralph E. McGinnis, Valgerður Steinthórsdóttir, Nicholas Williams, Guðmar Þorleifsson, Scott Shooter, Sigrun Hjartardottir, Suzannah Bumpstead, Lilja Stefánsdóttir, Lucy Hildyard, Jon Karl Sigurdsson et al. · 2017 · Nature Genetics
73. Genetic signatures of high-altitude adaptation in Tibetans
    Jian Yang, Zi‐Bing Jin, Jie Chen, Xiu‐Feng Huang, Xiaoman Li, Yuanbo Liang, Jian-Yang Mao, Xin Chen, Zhili Zheng, Andrew Bakshi et al. · 2017 · Proceedings of the National Academy of Sciences
74. The Genetic Architecture of Gene Expression in Peripheral Blood
    Luke R. Lloyd‐Jones, Alexander Holloway, Allan F. McRae, Jian Yang, Kerrin S. Small, Jing Zhao, Biao Zeng, Andrew Bakshi, Andres Metspalu, Manolis Dermitzakis et al. · 2017 · The American Journal of Human Genetics
75. Prospects of Fine-Mapping Trait-Associated Genomic Regions by Using Summary Statistics from Genome-wide Association Studies
    Christian Benner, Aki Samuli Havulinna, Marjo‐Riitta Järvelin, Veikko V Salomaa, Samuli Ripatti, Matti Pirinen · 2017 · The American Journal of Human Genetics
76. An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk
    Lang Wu, Yaohua Yang, Xingyi Guo, Xiao‐Ou Shu, Qiuyin Cai, Xiang Shu, Bingshan Li, Ran Tao, Chong Wu, Jason B. Nikas et al. · 2020 · Nature Communications
77. Locus for severity implicates CNS resilience in progression of multiple sclerosis
    International Multiple Sclerosis Genetics Consortium, Harroud, Adil, Stridh, Pernilla, McCauley, Jacob L., Saarela, Janna, van den Bosch, Aletta M. R., Engelenburg, Hendrik J., Beecham, Ashley H., Alfredsson, Lars, Alikhani, Katayoun et al. · 2023 · Nature
78. Overview of Statistical Methods for Genome-Wide Association Studies (GWAS)
    Ben J. Hayes · 2013 · Methods in molecular biology
79. Genome-wide association study of medication-use and associated disease in the UK Biobank
    Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M., Wray, Naomi R. · 2019 · Nature Communications
80. Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes
    Novikova, Gloriia, Kapoor, Manav, TCW, Julia, Abud, Edsel M., Efthymiou, Anastasia G., Chen, Steven X., Cheng, Haoxiang, Fullard, John F., Bendl, Jaroslav, Liu, Yiyuan et al. · 2021 · Nature Communications
81. A comprehensive review on recent applications of unmanned aerial vehicle remote sensing with various sensors for high-throughput plant phenotyping
    Lei Feng, Shuangshuang Chen, Chu Zhang, Yan-Chao Sun Liang-Gui Zhang, Yong He · 2021 · Computers and Electronics in Agriculture
82. Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries
    Zhanju Liu, Ruize Liu, Han Gao, Seulgi Jung, Xiang Gao, Ruicong Sun, Xiaoming Liu, Yong‐Jae Kim, Ho‐Su Lee, Yosuke Kawai et al. · 2023 · Nature Genetics
83. Case–control association mapping by proxy using family history of disease
    Liu, Jimmy Z, Erlich, Yaniv, Pickrell, Joseph K · 2017 · Nature Genetics
84. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma
    Matthew H. Law, David Timothy Bishop, Jeffrey E. Lee, Myriam Brossard, Nicholas G. Martin, Eric Keith Moses, Fengju Song, Jennifer H. Barrett, Rajiv Kumar, Douglas F. Easton et al. · 2015 · Nature Genetics
85. Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes
    Heming Wang, Jacqueline M. Lane, Samuel E. Jones, Hassan S. Dashti, Hanna Maria Ollila, Andrew R. Wood, Vincent T. van Hees, Ben Michael Brumpton, Bendik Slagsvold Winsvold, Katri Kantojärvi et al. · 2019 · Nature Communications
86. Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
    Ceres Fernández–Rozadilla, Maria N Timofeeva, Zhishan Chen, Philip Law, Minta Thomas, Stephanie L. Schmit, Virginia Díez‐Obrero, Li Hsu, Juan J. Fernandez-Tajes, Claire Palles et al. · 2022 · Nature Genetics
87. Genome-Wide Complex Trait Analysis (GCTA): Methods, Data Analyses, and Interpretations
    Jian Yang, Sang Lee, Michael Edward Goddard, Peter M. Visscher · 2013 · Methods in molecular biology
88. Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia
    Cornelis Blauwendraat, Xylena Reed, Lynne Krohn, Karl Heilbron, Sara Bandrés‐Ciga, Manuela M. X. Tan, Jesse Raphael Gibbs, Dena G. Hernandez, Ravindran Kumaran, Rebekah G. Langston et al. · 2019 · Brain
89. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
    Jacob M. Keaton, Zoha Kamali, Tian Xie, Ahmad Vaez, Ariel Williams, Slavina B. Goleva, Alireza Ani, Εvangelos Εvangelou, Jacklyn N. Hellwege, Loïc Yengo et al. · 2024 · Nature Genetics
90. Population genetic differentiation of height and body mass index across Europe
    Matthew R. Robinson, Gibran Hemani, Carolina Medina‐Gómez, Massimo Mezzavilla, Tõnu Esko, Konstantin Shakhbazov, Joseph E. Powell, Anna A. E. Vinkhuyzen, Sonja I. Berndt, Stefan Gustafsson et al. · 2015 · Nature Genetics
91. Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility
    Maria Teresa Landi, David Timothy Bishop, Stuart MacGregor, Mitchell J. Machiela, Alexander Stratigos, Paola Ghiorzo, Myriam Brossard, Donato Calista, Jiyeon Choi, Maria Concetta Fargnoli et al. · 2020 · Nature Genetics
92. Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
    Zhe Wang, Andrew Emmerich, Nicolas J. Pillon, Timothy M. Moore, Daiane Hemerich, Marilyn C. Cornelis, Eugenia Mazzaferro, Siacia Broos, Tarunveer S. Ahluwalia, Traci M. Bartz et al. · 2022 · Nature Genetics
93. GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
    Pairo-Castineira, Erola, Rawlik, Konrad, Bretherick, Andrew D., Qi, Ting, Wu, Yang, Nassiri, Isar, McConkey, Glenn A., Zechner, Marie, Klaric, Lucija, Griffiths, Fiona et al. · 2023 · Nature
94. General Framework for Meta-analysis of Rare Variants in Sequencing Association Studies
    Seunggeun Lee, Tanya M. Teslovich, Michael Boehnke, Xihong Lin · 2013 · The American Journal of Human Genetics
95. Genomics yields biological and phenotypic insights into bipolar disorder
    Kevin Sean O’Connell, Maria Koromina, Tracey van der Veen, Toni A. Boltz, Friederike Sophie David, Jessica Mei Kay Yang, Keng‐Han Lin, Xin Wang, Jonathan R. I. Coleman, Brittany L. Mitchell et al. · 2025 · Nature
96. Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism
    Lindström, Sara, Wang, Lu, Smith, Erin N., Gordon, William, van Hylckama Vlieg, Astrid, de Andrade, Mariza, Brody, Jennifer A., Pattee, Jack W., Haessler, Jeffrey, Brumpton, Ben M. et al. · 2019 · Blood
97. Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
    Stuart MacGregor, Jue‐Sheng Ong, Jiyuan An, Xikun Han, Tiger Zhou, Owen M. Siggs, Matthew H. Law, Emmanuelle Souzeau, Shiwani Sharma, David John Lynn et al. · 2018 · Nature Genetics
98. Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
    Suzanne Vogelezang, Jonathan P. Bradfield, Tarunveer S. Ahluwalia, John A. Curtin, Timo Antero Lakka, Niels Grarup, Markus R. Scholz, Peter J. van der Most, Claire Monnereau, Evie Stergiakouli et al. · 2020 · PLoS Genetics
99. Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies
    Matthew Traylor, Elodie Persyn, Liisa Tomppo, Sofia Klasson, Vida Abedi, Mark K. Bakker, Nuria Torres, Linxin Li, Steven Bell, Loes C.A. Rutten‐Jacobs et al. · 2021 · The Lancet Neurology
100. A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
     NBCS Collaborators, Lang Wu, kConFab/AOCS Investigators, Wei Shi, Jirong Long, Xingyi Guo, Kyriaki Michailidou, Jonathan Beesley, Manjeet K. Bolla, Xiao‐Ou Shu et al. · 2018 · Nature Genetics