Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease
Open accessAbstract
We performed a meta-analysis of 2 genome-wide association studies of coronary artery disease comprising 1,515 cases and 5,019 controls followed by replication studies in 15,460 cases and 11,472 controls, all of Chinese Han ancestry. We identify four new loci for coronary artery disease that reached the threshold of genome-wide significance (P < 5 × 10(-8)). These loci mapped in or near TTC32-WDR35, GUCY1A3, C6orf10-BTNL2 and ATP2B1. We also replicated four loci previously identified in European populations (in or near PHACTR1, TCF21, CDKN2A-CDKN2B and C12orf51). These findings provide new insights into pathways contributing to the susceptibility for coronary artery disease in the Chinese Han population.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Of the 19 SNPs and high-LD proxies, associations were observed with multiple diseases or traits, including epithelial ovarian cancer, low-density lipoprotein cholesterol, coronary heart disease, luteinizing hormone and follicle-stimulating hormone levels, and age at onset for menopause.
“Of these, we observed associations with multiple diseases or traits, including epithelial ovarian cancer21, low-density lipoprotein cholesterol22, coronary heart disease23, luteinizing hormone and follicle-stimulating hormone levels, and age at onset for menopause24.”
From Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism (2017) · cites this paper as [23]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
PLINK: a tool set for whole-genome association and population-based linkage analyses.
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., Maller, J., Sklar, P., de Bakker, P. I. W., Daly, M. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/519795 · Cited by 34,089 · see citing works
Principal components analysis corrects for stratification in genome-wide association studies
Price, A. L., Patterson, N. J., Plenge, R. M., Weinblatt, M. E., Shadick, N. A., & Reich, D. (2006) · Nature Genetics · doi:10.1038/ng1847 · Cited by 10,248 · see citing works
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442 · see citing works
Self-citationHeart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association
Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Adams, R. J., Berry, J. D., Brown, T. M., Carnethon, M. R., Dai, S., de Simone, G., Ford, E. S., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182009701 · Cited by 6,149 · see citing works
The International HapMap Project
†The International HapMap Consortium, Genotyping centres: Baylor College of Medicine and ParAllele BioScience, Gibbs, R. A., Belmont, J. W., Hardenbol, P., Willis, T. D., Yu, F., Chinese HapMap Consortium, Yang, H., Ch'ang, L.-Y., et al. (2003) · Nature · doi:10.1038/nature02168 · Cited by 6,057 · see citing works
Self-citationPopulation Structure and Eigenanalysis
Patterson, N., Price, A. L., & Reich, D. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020190 · Cited by 5,280 · see citing works
METAL: fast and efficient meta-analysis of genomewide association scans
Willer, C. J., Li, Y., & Abecasis, G. R. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq340 · Cited by 5,205 · see citing works
Self-citationAntman, E. M., Bassand, J., Klein, W. W., Ohman, M. E., Sendón, J. L. L., Rydén, L., Simoons, M. L., & Tendera, M. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00804-4 · Cited by 4,824 · see citing works
Biological, clinical and population relevance of 95 loci for blood lipids
Teslovich, T. M., Musunuru, K., Smith, A. V., Edmondson, A. C., Stylianou, I. M., Koseki, M., Pirruccello, J. P., Ripatti, S., Chasman, D. I., Willer, C. J., et al. (2010) · Nature · doi:10.1038/nature09270 · Cited by 3,487 · see citing works
Self-citationGenomic Control for Association Studies
Devlin, B., & Roeder, K. (1999) · Biometrics · doi:10.1111/j.0006-341x.1999.00997.x · Cited by 3,162 · see citing works
Genomewide Association Analysis of Coronary Artery Disease
Samani, N. J., Erdmann, J., Hall, A. S., Hengstenberg, C., Mangino, M., Mayer, B., Dixon, R. J., Meitinger, T., Braund, P., Wichmann, H.-E., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa072366 · Cited by 2,044 · see citing works
Self-citationGenetic variants in novel pathways influence blood pressure and cardiovascular disease risk
The International Consortium for Blood Pressure Genome-Wide Association Studies (2011) · Nature · doi:10.1038/nature10405 · Cited by 2,033 · see citing works
Self-citationLarge-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Cardiogenics, Schunkert, H., the CARDIoGRAM Consortium, König, I. R., Kathiresan, S., Reilly, M. P., Assimes, T. L., Holm, H., Preuss, M., Stewart, A. F. R., et al. (2011) · Nature Genetics · doi:10.1038/ng.784 · Cited by 1,866 · see citing works
Self-citationMaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
Li, Y., Willer, C. J., Ding, J., Scheet, P., & Abecasis, G. R. (2010) · Genetic Epidemiology · doi:10.1002/gepi.20533 · Cited by 1,843 · see citing works
Self-citationA Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction
Helgadottir, A., Thorleifsson, G., Manolescu, A., Gretarsdottir, S., Blondal, T., Jonasdottir, A., Jonasdottir, A., Sigurdsson, A., Baker, A., Palsson, A., et al. (2007) · Science · doi:10.1126/science.1142842 · Cited by 1,594 · see citing works
Self-citationA Common Allele on Chromosome 9 Associated with Coronary Heart Disease
McPherson, R., Pertsemlidis, A., Kavaslar, N., Stewart, A., Roberts, R., Cox, D. R., Hinds, D. A., Pennacchio, L. A., Tybjaerg-Hansen, A., Folsom, A. R., et al. (2007) · Science · doi:10.1126/science.1142447 · Cited by 1,587 · see citing works
Genome-wide association study of blood pressure and hypertension
Levy, D., Ehret, G. B., Rice, K., Verwoert, G. C., Launer, L. J., Dehghan, A., Glazer, N. L., Morrison, A. C., Johnson, A. D., Aspelund, T., et al. (2009) · Nature Genetics · doi:10.1038/ng.384 · Cited by 1,364 · see citing works
Common variants at 30 loci contribute to polygenic dyslipidemia
Kathiresan, S., Willer, C. J., Peloso, G. M., Demissie, S., Musunuru, K., Schadt, E. E., Kaplan, L., Bennett, D., Li, Y., Tanaka, T., et al. (2009) · Nature Genetics · doi:10.1038/ng.291 · Cited by 1,364 · see citing works
Self-citationLong-term Consequences of Kawasaki Disease
Kato, H., Sugimura, T., Akagi, T., Sato, N., Hashino, K., Maeno, Y. V., Kazue, T., Eto, G., & Yamakawa, R. (1996) · Circulation · doi:10.1161/01.cir.94.6.1379 · Cited by 1,345 · see citing works
The diagnosis of ischaemic heart pain and intermittent claudication in field surveys.
Rose, G. A. (1962) · Europe PMC (PubMed Central) · Cited by 1,328 · see citing works
Alpert, J. S., Thygesen, K. A., Antman, E. M., & Bassand, J. (2001) · Journal of the American College of Cardiology · Cited by 1,282 · see citing works
Genome-wide association study identifies eight loci associated with blood pressure
Wellcome Trust Case Control Consortium, Newton-Cheh, C., Johnson, T., Gateva, V., Tobin, M. D., Bochud, M., Coin, L., Najjar, S. S., Zhao, J. H., Heath, S. C., et al. (2009) · Nature Genetics · doi:10.1038/ng.361 · Cited by 1,215 · see citing works
Self-citationMajor Causes of Death among Men and Women in China
He, J., Gu, D., Wu, X., Reynolds, K., Duan, X., Yao, C., Wang, J., Chen, C.-S., Chen, J., Wildman, R. P., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmsa050467 · Cited by 1,129 · see citing works
Self-citationMyocardial Infarction Genetics Consortium (2009) · Nature Genetics · doi:10.1038/ng.327 · Cited by 1,088 · see citing works
Li, Y., Willer, C., Sanna, S., & Abecasis, G. (2009) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.9.081307.164242 · Cited by 990 · see citing works
Self-citationPrevalence of the metabolic syndrome and overweight among adults in China
Gu, D., Reynolds, K., Wu, X., Chen, J., Duan, X., Reynolds, R. F., Whelton, P. K., & He, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66375-1 · Cited by 917 · see citing works
Self-citationSequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Gudbjartsson, D. F., Björnsdóttir, U. S., Halapi, E. C., Helgadóttir, A., Sulem, P., Jonsdottir, G. M., Þorleifsson, G., Helgadottir, H. T., Steinthórsdóttir, V., Stefánsson, H., et al. (2009) · Nature Genetics · doi:10.1038/ng.323 · Cited by 761 · see citing works
Self-citationSoluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease
Stasch, J., Pacher, P., & Evgenov, O. V. (2011) · Circulation · doi:10.1161/circulationaha.110.981738 · Cited by 602 · see citing works
Kato, N., Takeuchi, F., Tabara, Y., Kelly, T. N., Go, M. J., Sim, X., Tay, W. T., Chen, C.-H., Zhang, Y., Yamamoto, K., et al. (2011) · Nature Genetics · doi:10.1038/ng.834 · Cited by 563 · see citing works
Self-citationSoranzo, N., Spector, T. D., Mangino, M., Kuehnel, B., Rendon, A., Teumer, A., Willenborg, C., Wright, B. J., Chen, L., Li, M., et al. (2009) · Nature Genetics · doi:10.1038/ng.467 · Cited by 520 · see citing works
Self-citationSarcoidosis is associated with a truncating splice site mutation in BTNL2
Valentonyte, R., Hampe, J., Huse, K., Rosenstiel, P. C., Albrecht, M., Stenzel, A., Nagy, M., Gaede, K. I., Franke, A., Häsler, R., et al. (2005) · Nature Genetics · doi:10.1038/ng1519 · Cited by 487 · see citing works
Kim, Y. J., Go, M. J., Hu, C., Hong, C. B., Kim, Y. K., Lee, J. Y., Hwang, J., Oh, J. H., Kim, D. J., Kim, N. H., et al. (2011) · Nature Genetics · doi:10.1038/ng.939 · Cited by 293 · see citing works
Wang, F., Xu, C., He, Q. W., Cai, J., Li, X.-C., Wang, D., Xiong, X., Liao, Y.-H., Zeng, Q.-T., Yang, Y.-Z., et al. (2011) · Nature Genetics · doi:10.1038/ng.783 · Cited by 251 · see citing works
Self-citationGenome-wide association study of coronary artery disease in the Japanese
Takeuchi, F., Yokota, M., Yamamoto, K., Nakashima, E., Katsuya, T., Asano, H., Isono, M., Nabika, T., Sugiyama, T., Fujioka, A., et al. (2011) · European Journal of Human Genetics · doi:10.1038/ejhg.2011.184 · Cited by 163 · see citing works
Tetratricopeptide repeat cochaperones in steroid receptor complexes
Smith, D. F. (2004) · Cell stress & chaperones (Print) · doi:10.1379/csc-31.1 · Cited by 156 · see citing works
Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour
Peden, J. F., & Farrall, M. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr384 · Cited by 142 · see citing works
Clancy, R. M., Marion, M. C., Kaufman, K. M., Ramos, P. S., Adler, A., Harley, J. B., Langefeld, C. D., & Buyon, J. P. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27658 · Cited by 85 · see citing works
Jin, Y., Birlea, S. A., Fain, P. R., Gowan, K., Riccardi, S. L., Holland, P. J., Bennett, D. C., Herbstman, D. M., Wallace, M. R., McCormack, W. T., et al. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.12 · Cited by 81 · see citing works
Hou, L., Chen, S., Yu, H., Lu, X., Chen, J., Wang, L., Huang, J., Fan, Z., & Gu, D. (2008) · Human Genetics · doi:10.1007/s00439-008-0587-4 · Cited by 69 · see citing works
Self-citationThe plasma membrane calcium ATPase and disease
Tempel, B. L., & Shilling, D. J. (2007) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-1-4020-6191-2_13 · Cited by 36 · see citing works
Construction of Expression-ready cDNA Clones for KIAA Genes: Manual Curation of 330 KIAA cDNA Clones
Nakajima, D. (2002) · DNA Research · doi:10.1093/dnares/9.3.99 · Cited by 33 · see citing works
Hsueh, K., Lin, Y., Chang, J.-S., Wan, L., & Tsai, F. (2009) · European Journal of Pediatrics · doi:10.1007/s00431-009-1099-5 · Cited by 18 · see citing works
Flagged first, then by citations
1 of the 43 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K.-H., Cuenca-León, E., Muona, M., Furlotte, N. A., et al. (2016) · Nature Genetics · doi:10.1038/ng.3598 · Cited by 681 · see citing works
Self-citationClinical Interpretation and Implications of Whole-Genome Sequencing
Dewey, F., Grove, M. E., Pan, C., Goldstein, B., Bernstein, J., Chaib, H., Merker, J., Goldfeder, R., Enns, G., David, S., et al. (2014) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.2014.1717 · Cited by 456 · see citing works
Tcheandjieu, C., Zhu, X., Hilliard, A. T., Clarke, S. L., Napolioni, V., Ma, S., Lee, K. M., Fang, H., Chen, F., Lu, Y., et al. (2022) · Nature Medicine · doi:10.1038/s41591-022-01891-3 · Cited by 356 · see citing works
Self-citationIntegrating predicted transcriptome from multiple tissues improves association detection
Barbeira, A., Pividori, M., Zheng, J., Wheeler, H. E., Nicolae, D. L., & Im, H. K. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1007889 · Cited by 334 · see citing works
Sapkota, Y., Steinthorsdottir, V., Morris, A. P., Fassbender, A., Rahmioglu, N., De Vivo, I., Buring, J. E., Zhang, F., Edwards, T. L., Jones, S., et al. (2017) · Nature Communications · doi:10.1038/ncomms15539 · Cited by 344 · see citing works
Self-citationDysfunctional nitric oxide signalling increases risk of myocardial infarction
CARDIoGRAM, Erdmann, J., Stark, K. J., Esslinger, U. B., Rumpf, P. M., Koesling, D., de Wit, C., Kaiser, F. J., Braunholz, D., Medack, A., et al. (2013) · Nature · doi:10.1038/nature12722 · Cited by 287 · see citing works
Self-citationCarlson, C. S., Matise, T. C., North, K. E., Haiman, C. A., Fesinmeyer, M. D., Buyske, S. G., Schumacher, F. R., Peters, U., Franceschini, N., Ritchie, M. D., et al. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001661 · Cited by 258 · see citing works
Rahmioglu, N., Nyholt, D. R., Morris, A. P., Missmer, S. A., Montgomery, G. W., & Zondervan, K. T. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu015 · Cited by 238 · see citing works
Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection
International Stroke Genetics Consortium, Debette, S., the CADISP group, Kamatani, Y., Metso, T. M., Kloss, M., Chauhan, G., Engelter, S. T., Pezzini, A., Thijs, V., et al. (2015) · Nature Genetics · doi:10.1038/ng.3154 · Cited by 231 · see citing works
Practical considerations for plant phylogenomics
McKain, M. R., Johnson, M. G., Uribe‐Convers, S., Eaton, D. A. R., & Yang, Y. J. (2018) · Applications in Plant Sciences · doi:10.1002/aps3.1038 · Cited by 193 · see citing works
Self-citationDeletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation
Jia, M., Li, Q., Guo, J., Shi, W., Zhu, L., Huang, Y., Li, Y., Wang, L., Ma, S., Zhuang, T., et al. (2022) · Circulation Research · doi:10.1161/circresaha.121.319540 · Cited by 191 · see citing works
Self-citationJanssen, S. F., Gorgels, T. G. M. F., Ramdas, W. D., Klaver, C. C. W., van Duijn, C. M., Jansonius, N. M., & Bergen, A. A. B. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2013.09.001 · Cited by 185 · see citing works
Springelkamp, H., Iglesias, A. I., Mishra, A., Höhn, R., Wojciechowski, R., Khawaja, A. P., Nag, A., Wang, Y. X., Wang, J. J., Cuéllar-Partida, G., et al. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw399 · Cited by 173 · see citing works
Kessler, T., Vilne, B., & Schunkert, H. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201506174 · Cited by 172 · see citing works
Self-citationFeatures and applications of haplotypes in crop breeding
Bhat, J. A., Yu, D., Bohra, A., Ganie, S. A., & Varshney, R. K. (2021) · Communications Biology · doi:10.1038/s42003-021-02782-y · Cited by 182 · see citing works
Self-citationThe plasma membrane calcium pump in health and disease
Brini, M., Calí, T., Ottolini, D., & Carafoli, E. (2013) · FEBS Journal · doi:10.1111/febs.12193 · Cited by 169 · see citing works
Lu, X., Liu, Z., Cui, Q., Liu, F., Li, J., Niu, X., Shen, C., Hu, D., Huang, K., Chen, J., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac093 · Cited by 164 · see citing works
Self-citationLu, X., Peloso, G. M., Liu, D. J., Wu, Y., Zhang, H., Zhou, W., Li, J., Tang, C. S.-M., Dorajoo, R., Li, H., et al. (2017) · Nature Genetics · doi:10.1038/ng.3978 · Cited by 158 · see citing works
Self-citationSu, J. J., & Yu, D. S. F. (2021) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2021.104040 · Cited by 154 · see citing works
Self-citationXu, F., Fu, Y., Sun, T., Jiang, Z., Miao, Z., Shuai, M., Gou, W., Ling, C.-W., Yang, J., Wang, J., et al. (2020) · Microbiome · doi:10.1186/s40168-020-00923-9 · Cited by 148 · see citing works
Self-citationIntegrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
Miller, C. L., Pjanic, M., Wang, T., Nguyen, T., Cohain, A. T., Lee, J. D., Matic, L. P., Hedin, U., Kundu, R. K., Majmudar, D., et al. (2016) · Nature Communications · doi:10.1038/ncomms12092 · Cited by 146 · see citing works
Low-Grade Chronic Inflammation: a Shared Mechanism for Chronic Diseases
Cifuentes, M., Verdejo, H., Castro, P., Corvalán, A. H., Catterina Ferreccio, R., Quest, A. F. G., Kogan, M. J., & Lavandero, S. (2024) · Physiology · doi:10.1152/physiol.00021.2024 · Cited by 158 · see citing works
Li, L., Wang, L., Li, H., Han, X., Chen, S., Yang, B., Hu, Z., Zhu, H., Cai, C., Chen, J., et al. (2018) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2018.06.866 · Cited by 144 · see citing works
Self-citationThe Plasma Membrane Calcium ATP ases and Their Role as Major New Players in Human Disease
Stafford, N., Wilson, C., Oceandy, D., Neyses, L., & Cartwright, E. J. (2017) · Physiological Reviews · doi:10.1152/physrev.00028.2016 · Cited by 143 · see citing works
The role of aldehyde dehydrogenase 2 in cardiovascular disease
Zhang, J., Guo, Y., Zhao, X., Pang, J., Pan, C., Wang, J., Wei, S., Yu, X., Zhang, C., Chen, Y., et al. (2023) · Nature Reviews Cardiology · doi:10.1038/s41569-023-00839-5 · Cited by 142 · see citing works
Bennett, B. J., Davis, R. C., Civelek, M., Orozco, L. D., Wu, J., Qi, H., Pan, C., Packard, R. R. S., Eskin, E., Yan, M., et al. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005711 · Cited by 135 · see citing works
Self-citationA genome-wide association study of a coronary artery disease risk variant
Lee, J.-Y., Lee, B.-S., Shin, D.-J., Park, K. W., Shin, Y.-A., Kim, K. J., Heo, L., Lee, J. Y., Kim, Y. K., Kim, Y. J., et al. (2013) · Journal of Human Genetics · doi:10.1038/jhg.2012.124 · Cited by 139 · see citing works
Genetics of cardiovascular disease: Importance of sex and ethnicity
Winham, S. J., de Andrade, M., & Miller, V. M. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.03.021 · Cited by 131 · see citing works
Genetics and Genomics for the Prevention and Treatment of Cardiovascular Disease: Update
Ganesh, S. K., Arnett, D. K., Assimes, T. L., Basson, C. T., Chakravarti, A., Ellinor, P. T., Engler, M. B., Goldmuntz, E., Herrington, D. M., Hershberger, R. E., et al. (2013) · Circulation · doi:10.1161/01.cir.0000437913.98912.1d · Cited by 130 · see citing works
Polymorphic Variants of Adrenoceptors: Pharmacology, Physiology, and Role in Disease
Ahles, A., & Engelhardt, S. H. (2014) · Pharmacological Reviews · doi:10.1124/pr.113.008219 · Cited by 118 · see citing works
Genetics: Implications for Prevention and Management of Coronary Artery Disease
Assimes, T. L., & Roberts, R. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.10.039 · Cited by 116 · see citing works
Miller, C. L., Haas, U., Caceres, R. D., Leeper, N. J., Kundu, R. K., Patlolla, B., Assimes, T. L., Kaiser, F. J., Matic, L. P., Hedin, U., et al. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004263 · Cited by 112 · see citing works
Self-citationMatsunaga, H., Ito, K., Akiyama, M., Takahashi, A., Koyama, S., Nomura, S., Ieki, H., Ozaki, K., Onouchi, Y., Sakaue, S., et al. (2020) · Circulation Genomic and Precision Medicine · doi:10.1161/circgen.119.002670 · Cited by 109 · see citing works
Coronary Artery Disease Genetics Enlightened by Genome-Wide Association Studies
Kessler, T., & Schunkert, H. (2021) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2021.04.001 · Cited by 105 · see citing works
Self-citationA decade in psychiatric GWAS research
Horwitz, T. B., Lam, K., Chen, Y., Xia, Y., & Liu, C. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0055-z · Cited by 103 · see citing works
Development of the catfish 250K SNP array for genome-wide association studies
Liu, S., Sun, L., Li, Y., Sun, F., Jiang, Y., Zhang, Y., Zhang, J., Feng, J., Kaltenboeck, L., Kucuktas, H., et al. (2014) · BMC Research Notes · doi:10.1186/1756-0500-7-135 · Cited by 103 · see citing works
Self-citationGenome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients
Sharma, P., Garg, G., Kumar, A., Mohammad, F., Kumar, S. R., Tanwar, V. S., Sati, S., Sharma, A., Karthikeyan, G., Brahmachari, V., et al. (2014) · Gene · doi:10.1016/j.gene.2014.02.034 · Cited by 102 · see citing works
Identification of CAD candidate genes in GWAS loci and their expression in vascular cells
Erbilgin, A., Civelek, M., Romanoski, C. E., Pan, C., Hagopian, R., Berliner, J. A., & Lusis, A. J. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m037085 · Cited by 100 · see citing works
Nürnberg, S., Cheng, K. W., Raiesdana, A., Kundu, R. K., Miller, C. L., Kim, J. B., Arora, K., Carcamo‐Orive, I., Xiong, Y., Tellakula, N., et al. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005155 · Cited by 101 · see citing works
Nagao, M., Lyu, Q., Zhao, Q., Wirka, R. C., Bagga, J. S., Nguyen, T., Cheng, P. P., Kim, J. B., Pjanic, M., Miano, J. M., et al. (2019) · Circulation Research · doi:10.1161/circresaha.119.315968 · Cited by 99 · see citing works
Self-citationBeaudoin, M., Gupta, R. M., Won, H., Lo, K. S., Do, R., Henderson, C. A., Lavoie-St-Amour, C., Langlois, S., Rivas, D., Lehoux, S., et al. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.305534 · Cited by 86 · see citing works
Self-citationThe Role of Endothelial Cells in Atherosclerosis
Pepin, M. E., & Gupta, R. M. (2023) · American Journal Of Pathology · doi:10.1016/j.ajpath.2023.09.012 · Cited by 75 · see citing works
Genetics of Coronary Artery Disease
Lieb, W., & Vasan, R. S. (2013) · Circulation · doi:10.1161/circulationaha.113.005350 · Cited by 75 · see citing works
Miller, C. L., Anderson, D. R., Kundu, R. K., Raiesdana, A., Nürnberg, S., Caceres, R. D., Cheng, K. W., Leeper, N. J., Chen, C., Chang, I., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003652 · Cited by 74 · see citing works
Calcium-ATPases: Gene disorders and dysregulation in cancer
Dang, D. K., & Rao, R. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.11.016 · Cited by 73 · see citing works
Polygenic risk scores for the prediction of cardiometabolic disease
O’Sullivan, J. W., Ashley, E. A., & Elliot, P. M. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac648 · Cited by 73 · see citing works
Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases
Wang, Y., & Wang, J. (2018) · Pulse · doi:10.1159/000496150 · Cited by 71 · see citing works
Uribe‐Convers, S., Settles, M. L., & Tank, D. C. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148203 · Cited by 70 · see citing works
Regulation of Cell Calcium and Role of Plasma Membrane Calcium ATPases
Calí, T., Brini, M., & Carafoli, E. (2017) · International review of cytology · doi:10.1016/bs.ircmb.2017.01.002 · Cited by 70 · see citing works
Vargas, J. D., Manichaikul, A. W., Wang, X., Rich, S. S., Rotter, J. I., Post, W. S., Polak, J. F., Budoff, M. J., & Bluemke, D. A. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.11.034 · Cited by 66 · see citing works
Genetic Variants Associated with Myocardial Infarction and the Risk Factors in Chinese Population
Wang, Y., Wang, L., Liu, X., Zhang, Y., Yu, L., Zhang, F., Liu, L., Cai, J., Yang, X., & Wang, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086332 · Cited by 65 · see citing works
Self-citationPsoriasis and Cardiometabolic Traits: Modest Association but Distinct Genetic Architectures
Koch, M., Baurecht, H., Ried, J. S., Rodríguez, E., Schlesinger, S., Volks, N., Gieger, C., Rückert, I.-M., Heinrich, L., Willenborg, C., et al. (2015) · Journal of Investigative Dermatology · doi:10.1038/jid.2015.8 · Cited by 65 · see citing works
Self-citationLu, X., Huang, J., Mo, Z., He, J., Wang, L., Yang, X., Tan, A., Chen, S., Chen, J., Gu, C. C., et al. (2015) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.115.001096 · Cited by 64 · see citing works
Self-citationArvind, P., Nair, J., Jambunathan, S., Kakkar, V. V., & Shanker, J. (2014) · Journal of Cardiology · doi:10.1016/j.jjcc.2014.02.012 · Cited by 60 · see citing works
From genotype to phenotype in human atherosclerosis - recent findings
Holdt, L. M., & Teupser, D. (2013) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283654e7c · Cited by 62 · see citing works
The Role of NO/sGC/cGMP/PKG Signaling Pathway in Regulation of Platelet Function
Gambaryan, S. P. (2022) · Cells · doi:10.3390/cells11223704 · Cited by 61 · see citing works
Hirokawa, M., Morita, H., Tajima, T., Takahashi, A., Ashikawa, K., Miya, F., Shigemizu, D., Ozaki, K., Sakata, Y., Nakatani, D., et al. (2014) · European Journal of Human Genetics · doi:10.1038/ejhg.2014.110 · Cited by 59 · see citing works
Chen, S., Wang, X., Wang, J., Zhao, Y., Wang, D., Tan, C., Fa, J., Zhang, R., Wang, F., Xu, C., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.01.008 · Cited by 59 · see citing works
Self-citationGao, J., He, L.-H., Yu, X.-H., Zhao, Z.-W., Wang, G., Zou, J., Wen, F.-J., Zhou, L., Wan, X.-J., Zhang, D., et al. (2019) · Journal of Lipid Research · doi:10.1194/jlr.ra119000100 · Cited by 59 · see citing works
Self-citationThe Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change
Weber, S. M., & Carroll, S. L. (2021) · American Journal Of Pathology · doi:10.1016/j.ajpath.2021.05.008 · Cited by 58 · see citing works
The plasma membrane calcium pumps: focus on the role in (neuro)pathology
Brini, M., Carafoli, E., & Calí, T. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.07.117 · Cited by 57 · see citing works
Somatic and Germline Variants and Coronary Heart Disease in a Chinese Population
Zhao, K., Shen, X., Liu, H., Lin, Z., Li, J., Chen, S., Liu, F., Huang, K., Cao, J., Liu, X., et al. (2024) · JAMA Cardiology · doi:10.1001/jamacardio.2023.5095 · Cited by 59 · see citing works
Self-citationNürnberg, S., Zhang, H., Hand, N. J., Bauer, R. C., Saleheen, D., Reilly, M. P., & Rader, D. J. (2016) · Circulation Research · doi:10.1161/circresaha.115.306464 · Cited by 55 · see citing works
Self-citationThe IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population.
Tu, X., Nie, S., Liao, Y.-H., Zhang, H., Fan, Q., Xu, C.-Q., Bai, Y., Wang, F., Ren, X., Tang, T., et al. (2013) · American Journal of Human Genetics · doi:10.1016/j.ajhg.2013.08.009 · Cited by 53 · see citing works
Self-citationLocal genetic effects on gene expression across 44 human tissuesPreprint
Aguet, F., Brown, A. A., Castel, S. E., Davis, J. R., Mohammadi, P., Segrè, A. V., Zappala, Z., Abell, N. S., Frésard, L., Gamazon, E. R., et al. (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/074450 · Cited by 58 · see citing works
Self-citationJohansson, Å., Eriksson, N., Lindholm, D. P., Varenhorst, C., James, S. K., Syvänen, A., Axelsson, T., Siegbahn, A., Barratt, B. J., Becker, R. C., et al. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw012 · Cited by 53 · see citing works
Zhao, Q., Wirka, R. C., Nguyen, T., Nagao, M., Cheng, P. P., Miller, C. L., Kim, J. B., Pjanic, M., & Quertermous, T. (2019) · Genome Medicine · doi:10.1186/s13073-019-0635-9 · Cited by 52 · see citing works
Self-citationDeficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis
Kasikara, C., Schilperoort, M., Gerlach, B. D., Xue, C., Wang, X., Zheng, Z., Kuriakose, G., Dorweiler, B., Zhang, H., Fredman, G., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci145275 · Cited by 51 · see citing works
Self-citationLi, Y., Wang, D. W., Chen, Y., Chen, C., Guo, J., Zhang, S., Sun, Z., Ding, H., Yao, Y., Zhou, L., et al. (2018) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.117.310594 · Cited by 50 · see citing works
Self-citationRoberts, R., Chang, C. C., & Hadley, T. D. (2021) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2020.09.004 · Cited by 50 · see citing works
The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases
Chew, N., Chong, B., Ng, C. H., Kong, G., Chin, Y. H., Xiao, W., Lee, C. J. M., Dan, Y. Y., Muthiah, M. D., & Foo, R. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.971484 · Cited by 49 · see citing works
Posadas‐Sánchez, R., López-Uribe, Á. R., Posadas‐Romero, C., Pérez‐Hernández, N., Rodrı́guez-Pérez, J. M., Ocampo-Arcos, W. A., Fragoso, J. M., Cardoso-Saldaña, G. C., & Vargas‐Alarcón, G. (2016) · Immunobiology · doi:10.1016/j.imbio.2016.08.008 · Cited by 48 · see citing works
Genetic alterations in the NO-cGMP pathway and cardiovascular risk
Wobst, J., Schunkert, H., & Kessler, T. (2018) · Nitric Oxide · doi:10.1016/j.niox.2018.03.019 · Cited by 48 · see citing works
Self-citationCandidate Gene Association Study of Coronary Artery Calcification in Chronic Kidney Disease
Ferguson, J. F., Matthews, G. J., Townsend, R. R., Raj, D. S., Kanetsky, P. A., Budoff, M. J., Fischer, M. J., Rosas, S. E., Kanthety, R., Rahman, M., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.01.103 · Cited by 47 · see citing works
Self-citationYamada, Y., Kato, K., Oguri, M., Horibe, H., Fujimaki, T., Yasukochi, Y., Takeuchi, I., & Sakuma, J. (2018) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2018.3852 · Cited by 48 · see citing works
Reschen, M. E., Lin, D., Chalisey, A., Soilleux, E. J., & O’Callaghan, C. A. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.04.025 · Cited by 45 · see citing works
Rippe, C., Zhu, B., Krawczyk, K. K., VanBavel, E., Albinsson, S., Sjölund, J., Bakker, E. N. T. P., & Swärd, K. (2017) · Scientific Reports · doi:10.1038/s41598-017-01392-1 · Cited by 46 · see citing works
Common variants at 12q24 are associated with drinking behavior in Han Chinese
Yang, X., Lu, X., Wang, L., Chen, S., Li, J., Cao, J., Chen, J., Hao, Y., Li, Y., Zhao, L., et al. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.046482 · Cited by 44 · see citing works
Self-citationLarge‐Scale Gene‐Centric Analysis Identifies Polymorphisms for Resistant Hypertension
Fontana, V., McDonough, C. W., Gong, Y., Rouby, N. M. E., Sá, A. C. C., Taylor, K. D., Chen, Y. I., Gums, J. G., Chapman, A. B., Turner, S. T., et al. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.001398 · Cited by 43 · see citing works
Liu, J. B., Yang, H., Lee, M., Jen, C., Hu, H.-H., Lu, S., Wang, L., You, S., Huang, Y., & Chen, C. (2016) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-15-0961 · Cited by 43 · see citing works
Self-citationBastami, M., Ghaderian, S. M. H., Omrani, M. D., Mirfakhraie, R., Vakili, H., Parsa, S. A., Nariman‐Saleh‐Fam, Z., & Masotti, A. (2016) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2015.0253 · Cited by 43 · see citing works
Dechamethakun, S., Ikeda, S., Arai, T., Sato, N., Sawabe, M., & Muramatsu, M. (2014) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.22640 · Cited by 40 · see citing works
Aherrahrou, R., Aherrahrou, Z., Schunkert, H., & Erdmann, J. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.07.090 · Cited by 40 · see citing works
Self-citationTranscriptional Control of Cell Lineage Development in Epicardium-Derived Cells
Braitsch, C. M., & Yutzey, K. E. (2013) · Journal of Developmental Biology · doi:10.3390/jdb1020092 · Cited by 40 · see citing works
Wangler, M. F., Hu, Y., & Shulman, J. M. (2017) · Disease Models & Mechanisms · doi:10.1242/dmm.027680 · Cited by 38 · see citing works
Genomic Variant in IL-37 Confers A Significant Risk of Coronary Artery Disease
Yin, D., Naji, D. H., Xia, Y., Li, S., Bai, Y., Jiang, G., Zhao, Y., Wang, X., Huang, Y., Chen, S., et al. (2017) · Scientific Reports · doi:10.1038/srep42175 · Cited by 39 · see citing works
Self-citationPalmisano, B. T., Le, T. D. V., Zhu, L., Lee, Y., & Stafford, J. M. (2016) · Journal of Lipid Research · doi:10.1194/jlr.m069013 · Cited by 39 · see citing works
Shared genes between Alzheimer’s disease and ischemic stroke
Wei, C., Cui, P., Li, H., Lang, W., Liu, G., & Ma, X. (2019) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13117 · Cited by 37 · see citing works
Self-citationPathogenesis of premature coronary artery disease: Focus on risk factors and genetic variants
Wang, H., Liu, Z., Shao, J., Jiang, M., Lu, X.-C., Lin, L., Wang, L., Xu, Q., Zhang, H. S., Li, X., et al. (2020) · Genes & Diseases · doi:10.1016/j.gendis.2020.11.003 · Cited by 44 · see citing works
Self-citationHan, Y. Y., Dorajoo, R., Chang, X., Wang, L., Khor, C. C., Sim, X., Cheng, C., Shi, Y., Tham, Y. C., Zhao, W., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-18214-z · Cited by 37 · see citing works
Self-citationHu, H., Lin, S., Wang, S., & Chen, X. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00457 · Cited by 37 · see citing works
Association between the SIRT1 mRNA Expression and Acute Coronary Syndrome
Hu, Y., Wang, L., Chen, S., Liu, X., Li, H., Lu, X., Yang, X., Huang, J., & Gu, D. (2014) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.24844 · Cited by 36 · see citing works
Self-citationMilenković, D., Berghe, W. V., Morand, C., Claude, S., van de Sandt, A. M., Gorreßen, S., Monfoulet, L., Chirumamilla, C. S., Declerck, K., Szic, K. S. V., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-33959-x · Cited by 35 · see citing works
Hall, K. T., Kessler, T., Buring, J. E., Passow, D., Sesso, H. D., Zee, R. Y. L., Ridker, P. M., Chasman, D. I., & Schunkert, H. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz384 · Cited by 35 · see citing works
Self-citationDevelopmental Pathways of Cardiac FibroblastsPreprint
Tallquist, M. D. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a037184 · Cited by 34 · see citing works
Ide, S., Finer, G., Maezawa, Y., Onay, T., Souma, T., Scott, R. P., Ide, K., Akimoto, Y., Li, C., Ye, M., et al. (2018) · Journal of the American Society of Nephrology · doi:10.1681/asn.2017121278 · Cited by 33 · see citing works
De novo PHACTR1 mutations in West syndrome and their pathophysiological effects
Hamada, N., Ogaya, S., Nakashima, M., Nishijo, T., Sugawara, Y., Iwamoto, I., Ito, H., Maki, Y., Shirai, K., Baba, S., et al. (2018) · Brain · doi:10.1093/brain/awy246 · Cited by 33 · see citing works
Yamada, Y., Yasukochi, Y., Kato, K., Oguri, M., Horibe, H., Fujimaki, T., Takeuchi, I., & Sakuma, J. (2018) · Biomedical Reports · doi:10.3892/br.2018.1152 · Cited by 32 · see citing works
Genome-wide association study in Han Chinese identifies three novel loci for human height
Hao, Y., Liu, X., Lu, X., Yang, X., Wang, L., Chen, S., Li, H., Li, J., Cao, J., Chen, J., et al. (2013) · Human Genetics · doi:10.1007/s00439-013-1280-9 · Cited by 32 · see citing works
Self-citationLiu, X., Wang, L., Li, H., Lu, X., Hu, Y., Yang, X., Huang, C. Y., & Gu, D. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.01.039 · Cited by 32 · see citing works
Self-citation
- Authors
- The Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Consortium, Lu, X., Wang, L., Chen, S., He, L., Yang, X., Shi, Y., Cheng, J., Zhang, L., Gu, C. C., Huang, J., Wu, T., Ma, Y., Li, J., Cao, J., Chen, J., Ge, D., Fan, Z., Li, Y., Zhao, L., Li, H., Zhou, X., Chen, L., Liu, D., Chen, J., Duan, X., Hao, Y., Wang, L., Lu, F., Liu, Z., Yao, C., Shen, C., Pu, X., Yu, L., Fang, X., Xu, L., Mu, J., Wu, X., Zheng, R., Wu, N., Zhao, Q., Li, Y., Liu, X., Wang, M., Yu, D., Hu, D., Ji, X., Guo, D., Sun, D., Wang, Q., Yang, Y., Liu, F., Mao, Q., Liang, X., Ji, J., Chen, P., Mo, X., Li, D., Chai, G., Tang, Y., Li, X., Du, Z., Liu, X., Dou, C., Yang, Z., Meng, Q., Wang, D., Wang, R., Yang, J., Schunkert, H., Samani, N. J., Kathiresan, S., Reilly, M. P., Erdmann, J., Peng, X., Wu, X., Liu, D., Yang, Y., Chen, R., Qiang, B., & Gu, D.
- Affiliations
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shanghai Jiao Tong University (CN)
- Tsinghua University (CN)
- Washington University in St. Louis (US)
- Huazhong University of Science and Technology (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Chinese National Human Genome Center (CN)
- Renmin Hospital of Wuhan University (CN)
- Shandong First Medical University (CN)
- Nanjing Medical University (CN)
- Fujian Provincial People's Hospital (CN)
- Capital Medical University (CN)
- Beihua University (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- North China University of Science and Technology (CN)
- Beijing Jishuitan Hospital (CN)
- Shenzhen University (CN)
- Chinese PLA General Hospital (CN)
- Shijiazhuang Great Wall Hospital (CN)
- German Centre for Cardiovascular Research (DE)
- University of Leicester (GB)
- Broad Institute (US)
- University of Pennsylvania (US)
- Chinese Academy of Sciences (CN)
- Corresponding author
- Gu, Dongfeng
- ORCID
- Lu, Xiangfeng
- Wang, Laiyuan
- Chen, Shufeng
- He, Lin
- Yang, Xueli
- Shi, Yongyong
- Cheng, Jing
- Zhang, Liang
- Gu, C Charles
- Huang, Jianfeng
- Wu, Tangchun
- Ma, Yitong
- Li, Jianxin
- Cao, Jie
- Ge, Dongliang
- Fan, Zhongjie
- Li, Ying
- Zhou, Xiaoyang
- Chen, Lanying
- Liu, Donghua
- Hao, Yongchen
- Wang, Ligui
- Liu, Zhendong
- Shen, Chong
- Yu, Lin
- Fang, Xianghua
- Mu, Jianjun
- Wu, Xianping
- Zhao, Qi
- Li, Yun
- Liu, Xiaoli
- Wang, Mengqin
- Yu, Dahai
- Hu, Dongsheng
- Sun, Dongling
- Wang, Qianqian
- Yang, Ying
- Liu, Fangchao
- Mao, Qunxia
- Liang, Xiaohua
- Chen, Panpan
- Mo, Xingbo
- Li, Dianjiang
- Li, Xiangdong
- Liu, Xuehui
- Wang, Dong
- Wang, Renping
- Schunkert, Heribert
- Samani, Nilesh J
- Kathiresan, Sekar
- Reilly, Muredach P
- Erdmann, Jeanette
- Peng, Xiaozhong
- Yang, Yuejin
- Chen, Runsheng
- Gu, Dongfeng
- Venue
- Nature Genetics
- Published
- 2012-07-01
- Volume
- 44
- Issue
- 8
- Pages
- 890-894
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- PMC
- PMC3927410
- OpenAlex
- W2001401424
- Cited by
- 319
- References
- 43
- Citations by year
- 2026: 14 · 2025: 9 · 2024: 10 · 2023: 13 · 2022: 18 · 2021: 20 · 2020: 16 · 2019: 22 · 2018: 33 · 2017: 29 · 2016: 42 · 2015: 25 · 2014: 37 · 2013: 30 · 2012: 1
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Genetics (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- IRIS (submittedVersion)
- Leicester Research Archive (University of Leicester) (submittedVersion)
- mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
- Site cant be reached (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- OPUS (Augsburg University) (submittedVersion)
- Funders
- National Institutes of Health (n01ag12100-57-0-2, n01hc55021-47-0-1, n01hc55020-39-0-0, n01hc55016-37-0-0, n01hc055022-024, n01hc55019-35-0-1, n01hc55018-38-0-1, n01hc55015-48-0-1)
- National Institute on Aging (N01-AG012100)
- National Heart, Lung, and Blood Institute (N01 HC055016, K24HL107643, R01HL087676, N01 HC055020, N01 HC055018, R01HL087647, N01 HC055022, N01 HC055019, N01 HC055021, N01 HC055015, R01HL089650)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- coronary artery disease, genetic susceptibility loci, Han Chinese, GUCY1A3, ATP2B1, PHACTR1, TCF21, CDKN2A/CDKN2B, genetic association
- MeSH terms
- Soluble Guanylyl Cyclase, Butyrophilins, China, Chromosome Mapping, Coronary Artery Disease, Cytoskeletal Proteins, Guanylate Cyclase, Humans, Membrane Glycoproteins, Proteins, Linkage Disequilibrium, Case-Control Studies, Receptors, Cytoplasmic and Nuclear, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide, White People, Asian People, Intracellular Signaling Peptides and Proteins, Plasma Membrane Calcium-Transporting ATPases, Hedgehog Proteins, Genome-Wide Association Study
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
