Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease
European Alzheimer's Disease Initiative (EADI), Lambert, Jean-Charles, Genetic and Environmental Risk in Alzheimer's Disease (GERAD), Alzheimer's Disease Genetic Consortium (ADGC), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), Ibrahim-Verbaas, Carla A, Harold, Denise, Naj, Adam C +178 more·2013·Nature Genetics
DOI 10.1038/ng.2802
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- Are Porphyromonas gingivalis Outer Membrane Vesicles Microbullets for Sporadic Alzheimer’s Disease Manifestation?Sim K. Singhrao, Ingar Olsen · 2018 · Journal of Alzheimer s Disease Reports
- Tau at the interface between neurodegeneration and neuroinflammationDidonna, Alessandro · 2020 · Genes & Immunity
- High blood pressure and risk of dementia: a two-sample mendelian randomization study in the UK BiobankSproviero, William, Winchester, Laura, Newby, Danielle, Fernandes, Marco, Shi, Liu, Goodday, Sarah M., Prats-Uribe, Albert, Alhambra, Daniel P., Buckley, Noel J., Nevado-Holgado, Alejo J. · 2021 · Biological Psychiatry
- Microglia metabolism in health and diseaseBorst, Katharina, Schwabenland, Marius, Prinz, Marco · 2019 · Neurochemistry International
- The complexities of the pathology–pathogenesis relationship in Alzheimer diseaseRudy J. Castellani, George L. Perry · 2014 · Biochemical Pharmacology
- Crowdsourced estimation of cognitive decline and resilience in Alzheimer's diseaseGenevera I. Allen, Nicola Amoroso, Catalina V. Anghel, Venkatachalapathy S. K. Balagurusamy, J Christopher Bare, Derek Beaton, R. Bellotti, David Alan Bennett, Kevin L. Boehme, Paul Christopher Boutros et al. · 2016 · Alzheimer s & Dementia
- Pleiotropic Effects of Trait-Associated Genetic Variation on DNA Methylation: Utility for Refining GWAS LociEilis J. Hannon, Mike Weedon, Nicholas J. Bray, Michael C. O’Donovan, Jonathan S. Mill · 2017 · The American Journal of Human Genetics
- Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia SpectrumKarch, Celeste M., Wen, Natalie, Fan, Chun C., Yokoyama, Jennifer S., Kouri, Naomi, Ross, Owen A., Höglinger, Gunter, Müller, Ulrich, Ferrari, Raffaele, Hardy, John et al. · 2018 · JAMA Neurology
- Alzheimer’s disease polygenic risk score as a predictor of conversion from mild-cognitive impairmentSultan Raja Chaudhury, Keeley J. Brookes, Tulsi Patel, Abigail Fallows, Tamar Guetta‐Baranes, James C. Turton, Rita João Guerreiro, José Brás, John Hardy, Paul T. Francis et al. · 2019 · Translational Psychiatry
- Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s diseaseAngela M. Crist, Kelly M. Hinkle, Xue Wang, Christina M. Moloney, Billie J. Matchett, Sydney A. Labuzan, Isabelle Frankenhauser, Nkem O. Azu, Amanda M. Liesinger, Elizabeth R. Lesser et al. · 2021 · Nature Communications
- Investigation of the Molecular Role of Brain-Derived Neurotrophic Factor in Alzheimer’s DiseasePragya Girotra, Tapan Behl, Aayush Sehgal, Sukhbir Singh, SIMONA GABRIELA BUNGAU · 2021 · Journal of Molecular Neuroscience
- Bidirectional links between Alzheimer's disease and Niemann–Pick type C diseaseMartina Malnar, Silva Katusic Hecimovic, Niklas Mattsson, Henrik Zetterberg · 2014 · Neurobiology of Disease
- Meta-Analysis of Parkinson’s Disease and Alzheimer’s Disease Revealed Commonly Impaired Pathways and Dysregulation of NRF2-Dependent GenesWang, Qian, Li, Wen-Xing, Dai, Shao-Xing, Guo, Yi-Cheng, Han, Fei-Fei, Zheng, Jun-Juan, Li, Gong-Hua, Huang, Jing-Fei · 2017 · Journal of Alzheimer s Disease
- Repurposing antihypertensive drugs for the prevention of Alzheimer’s disease: A mendelian randomization studyWalker, Venexia M, Kehoe, Patrick G, Martin, Richard M, Davies, Neil M · 2020 · International Journal of Epidemiology
- Risk factor SORL1: from genetic association to functional validation in Alzheimer’s diseaseOlav M. Andersen, Ina‐Maria Rudolph, Thomas E. Willnow · 2016 · Acta Neuropathologica
- Meta-analysis of epigenome-wide association studies of cognitive abilitiesRiccardo Emilio Marioni, Allan F. McRae, Jan Bressler, Elena Colicino, Eilis J. Hannon, Shuo Li, Diddier Prada, Jennifer A. Smith, Letizia Trevisi, Pei-Chien Tsai et al. · 2018 · Molecular Psychiatry
- Complement C7is a novel risk gene for Alzheimer's disease in Han ChineseDengfeng Zhang, Yu Fan, Min Xu, Guihong Wang, Dong Wang, Jin Li, Lili Kong, Hejiang Zhou, Rongcan Luo, Rui Bi et al. · 2018 · National Science Review
- Causal Effect of Lp(a) [Lipoprotein(a)] Level on Ischemic Stroke and Alzheimer DiseaseYuesong Pan, Hao Li, Yilong Wang, Xia Meng, Yongjun Wang · 2019 · Stroke
- Deletion of Alzheimer's disease‐associated CD33 results in an inflammatory human microglia phenotypeJannis Wißfeld, Ichiro Nozaki, Mona Mathews, Tamara Raschka, Christian Ebeling, Veit Hornung, Oliver Brüstle, Harald Neumann · 2021 · Glia
- Association between inflammatory biomarkers and all-cause, cardiovascular and cancer-related mortalityArchana Singh‐Manoux, Martin J. Shipley, Joshua A. Bell, Marianne Canonico, Alexis Elbaz, Mika Kivimaki B · 2016 · Canadian Medical Association Journal
- Ten Years of Tau-Targeted Immunotherapy: The Path Walked and the Roads AheadNovak, Petr, Kontsekova, Eva, Zilka, Norbert, Novak, Michal · 2018 · Frontiers in Neuroscience
- Genome-scale neurogenetics: methodology and meaningSteven A. McCarroll, Guoping Feng, Steven E. Hyman · 2014 · Nature Neuroscience
- The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer’s diseaseHussein N. Yassine, Varun Rawat, Wendy Jean Mack, Joseph F. Quinn, Karin Yurko‐Mauro, Eileen Bailey‐Hall, Paul S. S Aisen, Helena Chang Chui, Lon S. S. Schneider · 2016 · Alzheimer s Research & Therapy
- Systematic Analysis and Biomarker Study for Alzheimer’s DiseaseXinzhong Li, Haiyan Wang, Jintao Long, Genhua Pan, Taigang He, Oleg V. Anichtchik, Robert D. Belshaw, Diego Albani, Paul Edison, Elaine Green et al. · 2018 · Scientific Reports
- Friend, Foe or Both? Immune Activity in Alzheimer’s DiseaseGeorgia R. Frost, Lauren A. Jonas, Yue‐Ming Li · 2019 · Frontiers in Aging Neuroscience
- Artificial intelligence-driven multi-omics approaches in Alzheimer's disease: Progress, challenges, and future directionsRen, Fang, Wei, Jing, Chen, Qingxin, Hu, Mengling, Yu, Lu, Mi, Jianing, Zhou, Xiaogang, Qin, Dalian, Wu, Jianming, Wu, Anguo · 2025 · Acta Pharmaceutica Sinica B
- Introduction to special issue: Overview of Alzheimer's Disease Neuroimaging InitiativeMichael Walter Weiner, Dallas P. Veitch · 2015 · Alzheimer s & Dementia
- Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's diseasePuneet Talwar, Yumnam Silla, Sandeep Grover, Meenal Gupta, Rachna Agarwal, Suman S. Kushwaha, Ritushree Kukreti · 2014 · BMC Genomics
- TREM2-Dependent Effects on Microglia in Alzheimer’s DiseaseYingyue Zhou, Tyler Kent Ulland, Marco Colonna · 2018 · Frontiers in Aging Neuroscience
- Inflammation in Alzheimer’s Disease and Molecular Genetics: Recent UpdateZhigang Zhang, Yan Li, Cheung Toa Ng, You‐Qiang Song · 2015 · Archivum Immunologiae et Therapiae Experimentalis
- Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5A. Harrison Brody, Stephen M. Strittmatter · 2017 · Advances in pharmacology
- Shifting paradigms: The central role of microglia in Alzheimer’s diseaseSchwabe, Tina, Srinivasan, Karpagam, Rhinn, Herve · 2020 · Neurobiology of Disease
- Genomics implicates adaptive and innate immunity in Alzheimer’s and Parkinson’s diseasesGagliano, Sarah A., Pouget, Jennie G., Hardy, John, Knight, Jo, Barnes, Michael R., Ryten, Mina, Weale, Michael E. · 2016 · Annals of Clinical and Translational Neurology
- Calmodulin Binding Proteins and Alzheimer’s DiseaseDanton H. O’Day, Kristeen Eshak, Michael A. Myre · 2015 · Journal of Alzheimer s Disease
- Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s diseaseL. Winchester, J. Powell, S. Lovestone, A. Nevado-Holgado · 2018 · Genome Medicine
- Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer’s diseaseCarla Marie Startin, Nicholas James Ashton, Sarah Hamburg, Rosalyn Hithersay, Frances K. Wiseman, Kin Ying Mok, John Hardy, Alberto Lleó, Simon Lovestone, Lucilla Parnetti et al. · 2019 · Alzheimer s Research & Therapy
- Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s diseasePatrick, Ellis, Rajagopal, Sathyapriya, Wong, Hon-Kit Andus, McCabe, Cristin, Xu, Jishu, Tang, Anna, Imboywa, Selina H., Schneider, Julie A., Pochet, Nathalie, Krichevsky, Anna M. et al. · 2017 · Molecular Neurodegeneration
- Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary StatisticsJustin M. Luningham, Junyu Chen, Shizhen Tang, Philip L. De Jager, David A. A Bennett, Aron S. Buchman, Jingjing Yang · 2020 · The American Journal of Human Genetics
- AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer’s drug discoveryYadi Zhou, Jiansong Fang, Lynn M. Bekris, Young Heon Kim, Andrew A. Pieper, James B. Leverenz, Jeffrey L. Cummings, Feixiong Cheng · 2021 · Alzheimer s Research & Therapy
- Machine learning identifies interacting genetic variants contributing to breast cancer risk: A case study in Finnish cases and controlsBehravan, Hamid, Hartikainen, Jaana M., Tengström, Maria, Pylkäs, Katri, Winqvist, Robert, Kosma, Veli–Matti, Mannermaa, Arto · 2018 · Scientific Reports
- Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burdenHaure-Mirande, Jean-Vianney, Wang, Minghui, Audrain, Mickael, Fanutza, Tomas, Kim, Soong Ho, Heja, Szilvia, Readhead, Ben, Dudley, Joel T., Blitzer, Robert D., Schadt, Eric E. et al. · 2019 · Molecular Psychiatry
- Shared genetic etiology underlying Alzheimer’s disease and type 2 diabetesHao, Ke, Di Narzo, Antonio Fabio, Ho, Lap, Luo, Wei, Li, Shuyu, Chen, Rong, Li, Tongbin, Dubner, Lauren, Pasinetti, Giulio Maria · 2015 · Molecular Aspects of Medicine
- CR1 in Alzheimer's DiseaseXi‐Chen Zhu, Jin‐Tai Yu, Teng Jiang, Ping Wang, Lei Cao, Lan Tan · 2014 · Molecular Neurobiology
- Alzheimer disease risk genes: 29 and countingLars Bertram, Rudolph E. Tanzi · 2019 · Nature Reviews Neurology
- Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibilityChristopher Hartl, Gokul Ramaswami, William G. Pembroke, Sandrine Muller, Greta Pintacuda, Ashis Saha, Princy Parsana, Alexis J. Battle, Kasper Lage, Daniel H. Geschwind · 2021 · Nature Neuroscience
- Blood–brain barrier endothelial cells in neurodegenerative diseases: Signals from the “barrier”Yiwen Yuan, Jian Sun, Q. Dong, Mei Cui · 2023 · Frontiers in Neuroscience
- Inflammasome assembly in neurodegenerative diseasesSingh, Jagjit, Habean, Maria L., Panicker, Nikhil · 2023 · Trends in Neurosciences
- Eye-brain connections revealed by multimodal retinal and brain imaging geneticsBingxin Zhao, Yujue Li, Zirui Fan, Zhenyi Wu, Juan Shu, Xiaochen Yang, Yilin Yang, Xifeng Wang, Bingxuan Li, Xiyao Wang et al. · 2024 · Nature Communications
- Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and DementiaLoes C.A. Rutten‐Jacobs, Daniel J. Tozer, Marco Duering, Rainer Malik, Martin Dichgans, Hugh Stephen Markus, Matthew Traylor · 2018 · Stroke
- Association of social isolation, loneliness and genetic risk with incidence of dementia: UK Biobank Cohort StudyElovainio, Marko, Lahti, Jari, Pirinen, Matti, Pulkki-Råback, Laura, Malmberg, Anni, Lipsanen, Jari, Virtanen, Marianna, Kivimäki, Mika, Hakulinen, Christian · 2022 · BMJ Open
- Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individualsIghodaro, Eseosa T, Abner, Erin L, Fardo, David W, Lin, Ai-Ling, Katsumata, Yuriko, Schmitt, Frederick A, Kryscio, Richard J, Jicha, Gregory A, Neltner, Janna H, Monsell, Sarah E et al. · 2017 · Journal of Cerebral Blood Flow & Metabolism
- Age-Dependent Pleiotropy Between General Cognitive Function and Major Psychiatric DisordersWilliam David Hill, Gail Davies, David C M Liewald, Andrew Mark McIntosh, Ian J. Deary · 2015 · Biological Psychiatry
- Convergent Genetic and Expression Datasets Highlight TREM2 in Parkinson’s Disease SusceptibilityGuiyou Liu, Yongquan Liu, Qinghua Jiang, Yongshuai Jiang, Rennan Feng, Liangcai Zhang, Zugen Chen, Keshen Li, Jiafeng Liu · 2015 · Molecular Neurobiology
- Proteomic analysis of postsynaptic proteins in regions of the human neocortexMarcia M. Roy, Oksana Sorokina, Nathan Skene, Clémence Simonnet, Francesca Mazzo, Ruud Zwart, Emanuele Sher, Colin Smith, J. Douglas Armstrong, Seth G. N. Grant · 2017 · Nature Neuroscience
- Consequences of Metabolic Disruption in Alzheimer's Disease PathologyJ.C. Ryu, Eduardo Rigon Zimmer, Pedro Rosa‐Neto, Sung Ok Yoon · 2019 · Neurotherapeutics
- Childhood trauma, life-time self-harm, and suicidal behaviour and ideation are associated with polygenic scores for autismVarun Warrier, Simon Baron‐Cohen · 2019 · Molecular Psychiatry
- Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptomeDenis A. Baird, Jimmy Z. Liu, Jie Zheng, Solveig K. Sieberts, Thanneer Malai Perumal, Benjamin Elsworth, Tom G. Richardson, Chia‐Yen Chen, Minerva M. Carrasquillo, Mariet Allen et al. · 2021 · PLoS Genetics
- A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer’s disease and gastrointestinal tract disordersEmmanuel Olorunleke Adewuyi, Eleanor K. O’Brien, Dale R. Nyholt, Tenielle Porter, Simon Matthew Laws · 2022 · Communications Biology
- The Dual Role of Amyloid Beta-Peptide in Oxidative Stress and Inflammation: Unveiling Their Connections in Alzheimer’s Disease EtiopathologyHugo Fanlo-Ucar, Pol Picón-Pagès, Víctor Herrera-Fernández, Gerard ILL‐Raga, Francisco J. Muñoz · 2024 · Antioxidants
- Polygenic Analysis of Late-Onset Alzheimer’s Disease from Mainland ChinaBin Jiao, Xiaoyan Liu, Lin Zhou, Maggie Haitian Wang, Yafang Zhou, Tingting Xiao, Weiwei Zhang, Rui Sun, Mary Miu Yee Waye, Beisha Tang et al. · 2015 · PLoS ONE
- deTS : tissue-specific enrichment analysis to decode tissue specificityGuangsheng Pei, Yulin Dai, Zhongming Zhao, Peilin Jia · 2019 · Bioinformatics
- Cognitive subtypes of probable Alzheimer's disease robustly identified in four cohortsNienke M.E. Scheltens, Betty Marije Tijms, Teddy Koene, Frederik Barkhof, Charlotte Elisabeth Teunissen, Steffen Wolfsgruber, Michael Wagner, Johannes Kornhuber, Oliver Peters, Brendan I. Cohn‐Sheehy et al. · 2017 · Alzheimer s & Dementia
- Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseasesJanou A. Y. Roubroeks, Rebecca G. Smith, Daniël van den Hove, Katie Lunnon · 2017 · Journal of Neurochemistry
- Bioavailability and Pharmaco-therapeutic Potential of Luteolin in Overcoming Alzheimer’s DiseaseFahad R. Ali, Yasir Hasan Siddique · 2019 · CNS & Neurological Disorders - Drug Targets
- Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparitiesAlireza Nazarian, Anatoliy I. Yashin, Alexander M. Kulminski · 2019 · Alzheimer s Research & Therapy
- Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization studyAndrews, Shea J., Goate, Alison, Anstey, Kaarin J. · 2020 · Alzheimer's & Dementia
- An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 geneRoubroeks, Janou A.Y., Smith, Adam R., Smith, Rebecca G., Pishva, Ehsan, Ibrahim, Zina, Sattlecker, Martina, Hannon, Eilis J., Kłoszewska, Iwona, Mecocci, Patrizia, Soininen, Hilkka et al. · 2020 · Neurobiology of Aging
- The role of Alzheimer's disease risk genes in endolysosomal pathwaysMarcell P. Szabo, Swati Mishra, Allison Knupp, Jessica E. Young · 2021 · Neurobiology of Disease
- Genetics of CD33 in Alzheimer's disease and acute myeloid leukemiaManasi Malik, Joe W. Chiles, Hualin Simon Xi, Christopher Medway, James F. Simpson, Shobha Potluri, Dianna S. Howard, Liang Yu, Christian M. Paumi, Shubhabrata Mukherjee et al. · 2015 · Human Molecular Genetics
- microRNA single polynucleotide polymorphism influences on microRNA biogenesis and mRNA target specificityJarosław Króliczewski, Aleksandra Sobolewska, Dawid Lejnowski, James F. Collawn, Rafał Bartoszewski · 2017 · Gene
- Early Life Stress and Epigenetics in Late-onset Alzheimer’s Dementia: A Systematic ReviewErwin Lemche · 2018 · Current Genomics
- Analysis of Shared Heritability in Common Disorders of the Brain2016
- <i>APOE</i>
ε4 associates with microglial activation independently of Aβ plaques and tau tanglesFerrari-Souza, João Pedro, Lussier, Firoza Z., Leffa, Douglas T., Therriault, Joseph, Tissot, Cécile, Bellaver, Bruna, Ferreira, Pâmela C. L., Malpetti, Maura, Wang, Yi-Ting, Povala, Guilherme et al. · 2023 · Science Advances
- BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathologyTaga, Mariko, Petyuk, Vladislav A., White, Charles, Marsh, Galina, Ma, Yiyi, Klein, Hans-Ulrich, Connor, Sarah M., Kroshilina, Alexandra, Yung, Christina J., Khairallah, Anthony et al. · 2020 · Molecular Neurodegeneration
- Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in miceWu, Yu, Dong, Jing-Hua, Dai, Yong-Feng, Zhu, Min-Zhen, Wang, Meng-Yao, Zhang, Yuan, Pan, Yi-Da, Yuan, Xin-Rui, Guo, Zhi-Xin, Wang, Chen-Xi et al. · 2023 · Neuron
- The Contribution of Genetic Factors to Cognitive Impairment and Dementia: Apolipoprotein E Gene, Gene Interactions, and Polygenic RiskJialing Fan, Wuhai Tao, Xin Li, He Li, Junying Zhang, Dongfeng Wei, Yaojing Chen, Zhanjun Zhang · 2019 · International Journal of Molecular Sciences
- Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer’s disease riskShigemizu, Daichi, Mitsumori, Risa, Akiyama, Shintaro, Miyashita, Akinori, Morizono, Takashi, Higaki, Sayuri, Asanomi, Yuya, Hara, Norikazu, Tamiya, Gen, Kinoshita, Kengo et al. · 2021 · Translational Psychiatry
- An overview of the genes and biomarkers in Alzheimer’s diseaseHari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Tianhao Wang, Kang Bei, Chithra Changalath, John J. Rajasekaran · 2024 · Ageing Research Reviews
- Mitochondrial Lysates Induce Inflammation and Alzheimer's Disease-Relevant Changes in Microglial and Neuronal CellsHeather Wilkins, Steven M. Carl, Sam G. Weber, Suruchi Ramanujan, Barry W. Festoff, Daniel A. Linseman, Russell Howard Swerdlow · 2015 · Journal of Alzheimer s Disease
- ABCA1‐Mediated Cholesterol Efflux Capacity to Cerebrospinal Fluid Is Reduced in Patients With Mild Cognitive Impairment and Alzheimer's DiseaseYassine, Hussein N., Feng, Qingru, Chiang, Jiarong, Petrosspour, Larissa M., Fonteh, Alfred N., Chui, Helena C., Harrington, Michael G. · 2016 · Journal of the American Heart Association
- The Landscape of Circular RNA Expression in the Human BrainAkira Gokoolparsadh, Firoz Anwar, Irina Voineagu · 2019 · Biological Psychiatry
- INPP5D regulates inflammasome activation in human microgliaChou, Vicky, Pearse, Richard V., Aylward, Aimee J., Ashour, Nancy, Taga, Mariko, Terzioglu, Gizem, Fujita, Masashi, Fancher, Seeley B., Sigalov, Alina, Benoit, Courtney R. et al. · 2023 · Nature Communications
- A TREM 1 variant alters the accumulation of Alzheimer‐related amyloid pathologyJoseph M. Replogle, Gail Chan, Charles C. White, Towfique Raj, Phoebe A. Winn, Denis A. Evans, Reisa Anne Sperling, Lori Beth Chibnik, Elizabeth M. Bradshaw, Julie A. Schneider et al. · 2014 · Annals of Neurology
- ‘Big data’ in mental health research: current status and emerging possibilitiesRobert J. Stewart, Katrina A. S. Davis · 2016 · Social Psychiatry and Psychiatric Epidemiology
- DNA methylation alterations in Alzheimer’s diseaseAmy S. Yokoyama, John C. Rutledge, Valentina Medici · 2017 · Current Zoology
- Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and LossSalazar, Santiago V., Cox, Timothy O., Lee, Suho, Brody, A. Harrison, Chyung, Annabel S., Haas, Laura T., Strittmatter, Stephen M. · 2019 · The Journal of Neuroscience
- Predicting Alzheimer’s Disease Conversion From Mild Cognitive Impairment Using an Extreme Learning Machine-Based Grading Method With Multimodal DataWei-Ming Lin, Qinquan Gao, Jiangnan Yuan, Zhiying Chen, Chenwei Feng, Weisheng Chen, Min Du, Tong Tong · 2020 · Frontiers in Aging Neuroscience
- Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genesCharles E. Mordaunt, Julia M. Jianu, Benjamin I. Laufer, Yihui Zhu, Hyeyeon Hwang, Keith W. Dunaway, Kelly M. Bakulski, Jason I. Feinberg, Heather E. Volk, Kristen Lyall et al. · 2020 · Genome Medicine
- The Application of Artificial Intelligence in the Genetic Study of Alzheimer’s DiseaseRohan Mishra, Bin Li · 2020 · Aging and Disease
- Shared genetic risk loci between Alzheimer’s disease and related dementias, Parkinson’s disease, and amyotrophic lateral sclerosisMichael Wainberg, Shea J. Andrews, Shreejoy J. Tripathy · 2023 · Alzheimer s Research & Therapy
- Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology ConsortiumStéphanie Debette, Carla A. Ibrahim‐Verbaas, Jan Bressler, Maaike Schuur, Albert V. Smith, Joshua C. Bis, Gail Davies, Christiane Wolf, Vilmundur G. Gudnason, Lori Beth Chibnik et al. · 2014 · Biological Psychiatry
- Identification of Conserved Proteomic Networks in Neurodegenerative DementiaSwarup, Vivek, Chang, Timothy S., Duong, Duc M., Dammer, Eric B., Dai, Jingting, Lah, James J., Johnson, Erik C.B., Seyfried, Nicholas T., Levey, Allan I., Geschwind, Daniel H. · 2020 · Cell Reports
- BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylationSartori, Maxime, Mendes, Tiago, Desai, Shruti, Lasorsa, Alessia, Herledan, Adrien, Malmanche, Nicolas, Mäkinen, Petra, Marttinen, Mikael, Malki, Idir, Chapuis, Julien et al. · 2019 · Acta Neuropathologica
- Identification of conserved proteomic networks in neurodegenerative dementiaSwarup, Vivek, Chang, Timothy S., Duong, Duc M., Dammer, Eric B., Lah, James J., Johnson, Erik E.C.B., Seyfried, Nicholas T., Levey, Allan I., Geschwind, Daniel H. · 2019
- Epigenome-wide association study of Alzheimer’s disease replicates 22 differentially methylated positions and 30 differentially methylated regionsQingqin S. Li, Yu Sun, Tania Wang · 2020 · Clinical Epigenetics
- Oligomers of Amyloid β Prevent Physiological Activation of the Cellular Prion Protein-Metabotropic Glutamate Receptor 5 Complex by Glutamate in Alzheimer DiseaseHaas, Laura T., Strittmatter, Stephen M. · 2016 · Journal of Biological Chemistry
- Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's diseaseEmrin Horgusluoglu, Kwangsik T. Nho, Shannon L. Risacher, Sungeun Kim, Tatiana Foroud, Leslie M. J. Shaw, John Q. Trojanowski, Paul S. S. Aisen, Ronald Carl Petersen, Clifford R. Jack et al. · 2017 · Neurobiology of Aging
- Mitochondria in neuroinflammation – Multiple sclerosis (MS), leber hereditary optic neuropathy (LHON) and LHON-MSDavid Bargiela, Patrick Francis Chinnery · 2017 · Neuroscience Letters
- A Primer on Concepts and Applications of Proteomics in NeuroscienceFabian Hosp, Matthias Mann · 2017 · Neuron
- The immunogenetics of neurological diseaseMisra, Maneesh K., Damotte, Vincent, Hollenbach, Jill A. · 2018 · Immunology