Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease

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1. Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans
   Andrew J. Saykin, Li Shen, Xiaohui Yao, Sungeun Kim, Kwangsik T. Nho, Shannon L. Risacher, Vijay K. Ramanan, Tatiana Foroud, Kelley M. Faber, Nadeem Sarwar et al. · 2015 · Alzheimer s & Dementia
2. Aging and Alzheimer's disease: comparison and associations from molecular to system level
   Xia, Xian, Jiang, Quanlong, McDermott, Joseph, Han, Jing‐Dong J. · 2018 · Aging Cell
3. Novel genetic loci associated with hippocampal volume
   Hibar, Derrek P., Adams, Hieab H. H., Jahanshad, Neda, Chauhan, Ganesh, Stein, Jason L., Hofer, Edith, Renteria, Miguel E., Bis, Joshua C., Arias-Vasquez, Alejandro, Ikram, M. Kamran et al. · 2017 · Nature Communications
4. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy
   Cyril Laurent, Guillaume Dorothée, Stéphane Hunot, Elodie Martin, Yann Monnet, Marie Duchamp, Yuan Dong, François-Pierre Légeron, Antoine Leboucher, Sylvie Burnouf et al. · 2016 · Brain
5. The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study
   Sven J. van der Lee, Frank J. Wolters, M. Kamran Ikram, Albert Hofman D, M. Arfan Ikram, Najaf Amin, Cornelia M. van Duijn · 2018 · The Lancet Neurology
6. Microglial phagocytosis of neurons in neurodegeneration, and its regulation
   Claire Ann Butler, Alma S. Popescu, Emily J. A. Kitchener, David H. Allendorf, Mar Puigdellívol, Guy Charles Brown · 2021 · Journal of Neurochemistry
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   Shinohara, Mitsuru, Tachibana, Masaya, Kanekiyo, Takahisa, Bu, Guojun · 2017 · Journal of Lipid Research
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   Min Xu, Dengfeng Zhang, Rongcan Luo, Yong Wu, Hejiang Zhou, Lili Kong, Rui Bi, Yong‐Gang Yao · 2017 · Alzheimer s & Dementia
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   Wan, Ying-Wooi, Al-Ouran, Rami, Mangleburg, Carl G., Perumal, Thanneer M., Lee, Tom V., Allison, Katherine, Swarup, Vivek, Funk, Cory C., Gaiteri, Chris, Allen, Mariet et al. · 2020 · Cell Reports
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    Mancuso, Renzo, Van Den Daele, Johanna, Fattorelli, Nicola, Wolfs, Leen, Balusu, Sriram, Burton, Oliver, Liston, Adrian, Sierksma, Annerieke, Fourne, Yannick, Poovathingal, Suresh et al. · 2019 · Nature Neuroscience
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    Mehdi Jorfi, Anna Maaser‐Hecker, Rudolph E. Tanzi · 2023 · Genome Medicine
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    Bianco, Antonio C, Dumitrescu, Alexandra, Gereben, Balázs, Ribeiro, Miriam O, Fonseca, Tatiana L, Fernandes, Gustavo W, Bocco, Barbara M L C · 2019 · Endocrine Reviews
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    Miao, Jifei, Ma, Haixia, Yang, Yang, Liao, Yuanpin, Lin, Cui, Zheng, Juanxia, Yu, Muli, Lan, Jiao · 2023 · Frontiers in Aging Neuroscience
14. Association of Brain DNA Methylation in<i>SORL1</i>,<i>ABCA7</i>,<i>HLA-DRB5</i>,<i>SLC24A4</i>, and<i>BIN1</i>With Pathological Diagnosis of Alzheimer Disease
    Yu, Lei, Chibnik, Lori B., Srivastava, Gyan P., Pochet, Nathalie, Yang, Jingyun, Xu, Jishu, Kozubek, James, Obholzer, Nikolaus, Leurgans, Sue E., Schneider, Julie A. et al. · 2015 · JAMA Neurology
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    Udeochu, Joe C., Amin, Sadaf, Huang, Yige, Fan, Li, Torres, Eileen Ruth S., Carling, Gillian K., Liu, Bangyan, McGurran, Hugo, Coronas-Samano, Guillermo, Kauwe, Grant et al. · 2023 · Nature Neuroscience
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    Franzén, Oscar, Ermel, Raili, Cohain, Ariella, Akers, Nicholas K., Di Narzo, Antonio, Talukdar, Husain A., Foroughi-Asl, Hassan, Giambartolomei, Claudia, Fullard, John F., Sukhavasi, Katyayani et al. · 2016 · Science
17. Exosomes in the Pathology of Neurodegenerative Diseases
    Jason A. Howitt, Andrew Francis Hill · 2016 · Journal of Biological Chemistry
18. Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond
    Elise Cuyvers, Kristel Sleegers · 2016 · The Lancet Neurology
19. Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease
    Villegas-Llerena, Claudio, Phillips, Alexandra, Garcia-Reitboeck, Pablo, Hardy, John, Pocock, Jennifer M · 2016 · Current Opinion in Neurobiology
20. APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases
    Fernández-Calle, Rosalía, Konings, Sabine C., Frontiñán-Rubio, Javier, García-Revilla, Juan, Camprubí-Ferrer, Lluís, Svensson, Martina, Martinson, Isak, Boza-Serrano, Antonio, Venero, José Luís, Nielsen, Henrietta M. et al. · 2022 · Molecular Neurodegeneration
21. The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer’s Disease
    Fernandez, Celia G., Hamby, Mary E., McReynolds, Morgan L., Ray, William J. · 2019 · Frontiers in Aging Neuroscience
22. Molecular Pathogenesis of the Tauopathies
    Götz, Jürgen, Halliday, Glenda, Nisbet, Rebecca M. · 2019 · Annual Review of Pathology: Mechanisms of Disease
23. Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes
    Leah R. Zuroff, David A. Daley, Keith L. Black, Maya Koronyo‐Hamaoui · 2017 · Cellular and Molecular Life Sciences
24. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms
    Rebecca L. Walker, Gokul Ramaswami, Christopher Hartl, Nicholas Mancuso, Michael J. Gandal, Luis de la Torre-Ubieta, Bogdan Paşaniuc, Jason L. Stein, Daniel H. Geschwind · 2019 · Cell
25. Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies
    Lopes, Katia de Paiva, Snijders, Gijsje J. L., Humphrey, Jack, Allan, Amanda, Sneeboer, Marjolein A. M., Navarro, Elisa, Schilder, Brian M., Vialle, Ricardo A., Parks, Madison, Missall, Roy et al. · 2022 · Nature Genetics
26. The <i>MS4A</i> gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk
    Deming, Yuetiva, Filipello, Fabia, Cignarella, Francesca, Cantoni, Claudia, Hsu, Simon, Mikesell, Robert, Li, Zeran, Del-Aguila, Jorge L, Dube, Umber, Farias, Fabiana Geraldo et al. · 2019 · Science Translational Medicine
27. Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
    Zhang, Qian, Sidorenko, Julia, Couvy-Duchesne, Baptiste, Marioni, Riccardo E., Wright, Margaret J., Goate, Alison M., Marcora, Edoardo, Huang, Kuan-lin, Porter, Tenielle, Laws, Simon M. et al. · 2020 · Nature Communications
28. Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains
    Hans‐Ulrich Klein, Cristin Aubin, Elizabeta Gjoneska, Sarah E. Sullivan, Belinda J. Kaskow, Anna Y. Tang, Robert V. Smith, Jishu Xu, Andreas R. Pfenning, B Bernstein et al. · 2018 · Nature Neuroscience
29. The biological pathways of Alzheimer disease: a review
    Marco Calabrò, Carmela Rinaldi, Giuseppe Santoro, Concetta Crisafulli · 2020 · AIMS neuroscience
30. Mosaic Loss of Chromosome y in Blood Is Associated with Alzheimer Disease
    Dumanski, Jan P., Lambert, Jean-Charles, Rasi, Chiara, Giedraitis, Vilmantas, Davies, Hanna, Grenier-Boley, Benjamin, Lindgren, Cecilia M., Campion, Dominique, Dufouil, Carole, Pasquier, Florence et al. · 2016 · The American Journal of Human Genetics
31. Loss of Bin1 Promotes the Propagation of Tau Pathology
    Calafate, Sara, Flavin, William, Verstreken, Patrik, Moechars, Diederik · 2016 · Cell Reports
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    Kim N. Green, Joshua D. Crapser, Lindsay A. Hohsfield · 2020 · Trends in Immunology
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    Abdellaoui, Abdel, Hugh-Jones, David, Yengo, Loic, Kemper, Kathryn E., Nivard, Michel G., Veul, Laura, Holtz, Yan, Zietsch, Brendan P., Frayling, Timothy M., Wray, Naomi R. et al. · 2019 · Nature Human Behaviour
34. Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
    Deczkowska, Aleksandra, Matcovitch-Natan, Orit, Tsitsou-Kampeli, Afroditi, Ben-Hamo, Sefi, Dvir-Szternfeld, Raz, Spinrad, Amit, Singer, Oded, David, Eyal, Winter, Deborah R., Smith, Lucas K. et al. · 2017 · Nature Communications
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    Brian W. Kunkle, Michael A. Schmidt, Hans‐Ulrich Klein, Adam Christian Naj, Kara L. Hamilton‐Nelson, Eric Berg Larson, Denis A. Evans, Philip L. De Jager, Paul K. Crane, Joseph D. Buxbaum et al. · 2020 · JAMA Neurology
36. SumHer better estimates the SNP heritability of complex traits from summary statistics
    Speed, Doug, Balding, David J. · 2019 · Nature Genetics
37. The role of TREM2 in Alzheimer's disease and other neurodegenerative disorders
    Carmona, Susana, Zahs, Kathleen, Wu, Elizabeth, Dakin, Kelly, Bras, Jose, Guerreiro, Rita · 2018 · The Lancet Neurology
38. Multi-modal classification of Alzheimer's disease using nonlinear graph fusion
    Tong Tong, Katherine R. Gray, Qinquan Gao, Liang Chen, Daniel Rueckert · 2016 · Pattern Recognition
39. Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discovery
    Bing Bai, David Vanderwall, Yuxin Li, Xusheng Wang, Suresh Poudel, Hong Wang, Kaushik Kumar Dey, Ping‐Chung Chen, Ka Yang, Junmin Peng · 2021 · Molecular Neurodegeneration
40. APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease
    Nguyen, Aivi T., Wang, Kui, Hu, Gang, Wang, Xuran, Miao, Zhen, Azevedo, Joshua A., Suh, EunRan, Van Deerlin, Vivianna M., Choi, David, Roeder, Kathryn et al. · 2020 · Acta Neuropathologica
41. Genome-wide associations of human gut microbiome variation and implications for causal inference analyses
    David A. Hughes, Rodrigo Bacigalupe, Jun Wang, Malte Christoph Rühlemann, Raul Yhossef Tito, Gwen Falony, Marie Joossens, Sara Vieira‐Silva, Liesbet Henckaerts, Leen Rymenans et al. · 2020 · Nature Microbiology
42. Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation
    Bis, Joshua C., Jian, Xueqiu, Kunkle, Brian W., Chen, Yuning, Hamilton-Nelson, Kara L., Bush, William S., Salerno, William J., Lancour, Daniel, Ma, Yiyi, Renton, Alan E. et al. · 2020 · Molecular Psychiatry
43. Tau immunotherapy for Alzheimer's disease
    Pedersen, Jan Torleif, Sigurdsson, Einar M. · 2015 · Trends in Molecular Medicine
44. Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data
    Tylee, Daniel S., Sun, Jiayin, Hess, Jonathan L., Tahir, Muhammad A., Sharma, Esha, Malik, Rainer, Worrall, Bradford B., Levine, Andrew J., Martinson, Jeremy J., Nejentsev, Sergey et al. · 2018 · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
45. Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes
    Novikova, Gloriia, Kapoor, Manav, TCW, Julia, Abud, Edsel M., Efthymiou, Anastasia G., Chen, Steven X., Cheng, Haoxiang, Fullard, John F., Bendl, Jaroslav, Liu, Yiyuan et al. · 2021 · Nature Communications
46. Cellular and pathological functions of tau
    Celeste Parra Bravo, Sarah A. Naguib, Li Gan · 2024 · Nature Reviews Molecular Cell Biology
47. Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014
    Michael Walter Weiner, Dallas P. Veitch, Paul S. S. Aisen, Laurel A. Beckett, Nigel J. Cairns, Jesse M. Cedarbaum, Michael Donohue, Robert C. Green, Danielle J. Harvey, Clifford R. Jack et al. · 2015 · Alzheimer s & Dementia
48. Microglia in Brain Development, Homeostasis, and Neurodegeneration
    Bohlen, Christopher J., Friedman, Brad A., Dejanovic, Borislav, Sheng, Morgan · 2019 · Annual Review of Genetics
49. Case–control association mapping by proxy using family history of disease
    Liu, Jimmy Z, Erlich, Yaniv, Pickrell, Joseph K · 2017 · Nature Genetics
50. Retromer in Alzheimer disease, Parkinson disease and other neurological disorders
    Scott A. Small, Gregory A. Petsko · 2015 · Nature reviews. Neuroscience
51. Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model
    Dominic Holland, Oleksandr Frei, Rahul S. Desikan, Chun Chieh Fan, Alexey A. Shadrin, Olav Bjerkehagen Smeland, V. S. Sundar, Paul M. Thompson, Ole A. Andreassen, Anders Martin Dale · 2020 · PLoS Genetics
52. A Map of Transcriptional Heterogeneity and Regulatory Variation in Human Microglia
    Young, Adam M. H., Kumasaka, Natsuhiko, Calvert, Fiona, Hammond, Timothy R., Knights, Andrew, Panousis, Nikolaos, Park, Jun Sung, Schwartzentruber, Jeremy, Liu, Jimmy, Kundu, Kousik et al. · 2021 · Nature Genetics
53. Enrichr-KG: bridging enrichment analysis across multiple libraries
    John Erol Evangelista, Zhuorui Xie, Giacomo B. Marino, Nhi Le Uyen Nguyen, Daniel J. B. Clarke, Avi Ma’ayan · 2023 · Nucleic Acids Research
54. Assessment of the genetic variance of late-onset Alzheimer's disease
    Ridge, Perry G., Hoyt, Kaitlyn B., Boehme, Kevin, Mukherjee, Shubhabrata, Crane, Paul K., Haines, Jonathan L., Mayeux, Richard, Farrer, Lindsay A., Pericak-Vance, Margaret A., Schellenberg, Gerard D. et al. · 2016 · Neurobiology of Aging
55. A Test in Context: Neprilysin: Function, Inhibition, and Biomarker.
    A. Bayés-Genís, J. Barallat, A. M. Richards · 2016 · Journal of the American College of Cardiology
56. Novel genetic loci underlying human intracranial volume identified through genome-wide association
    H. Adams, D. Hibar, V. Chouraki, J. Stein, P. Nyquist, Miguel E. Rentería, S. Trompet, A. Arias-Vásquez, S. Seshadri, S. Desriviéres et al. · 2016 · Nature Neuroscience
57. Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms
    Li, Peipei, Marshall, Lee, Oh, Gabriel, Jakubowski, Jennifer L., Groot, Daniel, He, Yu, Wang, Ting, Petronis, Arturas, Labrie, Viviane · 2019 · Nature Communications
58. The Role of Sex and Sex Hormones in Neurodegenerative Diseases
    Elisabetta Vegeto, Alessandro Maria Villa, Sara Della Torre, V. Crippa, P. Rusmini, Riccardo Cristofani, M. Galbiati, Adriana C. Maggi, Angelo Poletti · 2019 · Endocrine Reviews
59. Molecular and Cellular Basis of Neurodegeneration in Alzheimer’s Disease
    Sangyun Jeong · 2017 · Molecules and Cells
60. A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex
    Marzi, Sarah J., Leung, Szi Kay, Ribarska, Teodora, Hannon, Eilis, Smith, Adam R., Pishva, Ehsan, Poschmann, Jeremie, Moore, Karen, Troakes, Claire, Al-Sarraj, Safa et al. · 2018 · Nature Neuroscience
61. Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system
    Yang, Sheng, Qin, Chuan, Hu, Zi-Wei, Zhou, Luo-Qi, Yu, Hai-Han, Chen, Man, Bosco, Dale B., Wang, Wei, Wu, Long-Jun, Tian, Dai-Shi · 2021 · Neurobiology of Disease
62. Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers
    Alzheimer’s Disease Neuroimaging Initiative (ADNI), Deming, Yuetiva, The Alzheimer Disease Genetic Consortium (ADGC), Li, Zeran, Kapoor, Manav, Harari, Oscar, Del-Aguila, Jorge L., Black, Kathleen, Carrell, David, Cai, Yefei et al. · 2017 · Acta Neuropathologica
63. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies
    Bras, Jose, Guerreiro, Rita, Darwent, Lee, Parkkinen, Laura, Ansorge, Olaf, Escott-Price, Valentina, Hernandez, Dena G., Nalls, Michael A., Clark, Lorraine N., Honig, Lawrence S. et al. · 2014 · Human Molecular Genetics
64. Whole-Genome Sequencing of a Healthy Aging Cohort
    Galina A. Erikson, Dale L. Bodian, Manuel Rueda, Bhuvan Molparia, Erick R. Scott, Ashley A. Scott‐Van Zeeland, Sarah E. Topol, Nathan E. Wineinger, John E. Niederhuber, Eric J. Topol et al. · 2016 · Cell
65. Associations between gut microbiota and Alzheimer’s disease, major depressive disorder, and schizophrenia
    Zhuang, Zhenhuang, Yang, Ruotong, Wang, Wenxiu, Qi, Lu, Huang, Tao · 2020 · Journal of Neuroinflammation
66. DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex
    Gasparoni, Gilles, Bultmann, Sebastian, Lutsik, Pavlo, Kraus, Theo F. J., Sordon, Sabrina, Vlcek, Julia, Dietinger, Vanessa, Steinmaurer, Martina, Haider, Melanie, Mulholland, Christopher B. et al. · 2018 · Epigenetics &amp; Chromatin
67. Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores
    Ganna Leonenko, Emily Ann Baker, Joshua O Stevenson‐Hoare, Annerieke S. R. Sierksma, Mark W. E. J. Fiers, Julie H. Williams, Bart De Strooper, Valentina Escott‐Price · 2021 · Nature Communications
68. Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease
    Zeng, Hu, Huang, Jiahao, Zhou, Haowen, Meilandt, William J., Dejanovic, Borislav, Zhou, Yiming, Bohlen, Christopher J., Lee, Seung-Hye, Ren, Jingyi, Liu, Albert et al. · 2023 · Nature Neuroscience
69. Is Alzheimer’s disease a systemic disease?
    Morris, Jill K., Honea, Robyn A., Vidoni, Eric D., Swerdlow, Russell H., Burns, Jeffrey M. · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
70. The SLC transporter in nutrient and metabolic sensing, regulation, and drug development
    Yong Zhang, Yuping Zhang, Kun Sun, Ziyi Meng, Ligong Chen · 2018 · Journal of Molecular Cell Biology
71. Genetic variants associated with longitudinal changes in brain structure across the lifespan
    Rachel M. Brouwer, Marieke Klein, Katrina L. Grasby, Hugo Gerard Schnack, Neda Jahanshad, Jalmar Teeuw, Sophia I. Thomopoulos, Emma Sprooten, Carol E. Franz, Nitin Gogtay et al. · 2022 · Nature Neuroscience
72. Cholesterol and Alzheimer’s Disease; From Risk Genes to Pathological Effects
    Feringa, Femke M., van der Kant, Rik · 2021 · Frontiers in Aging Neuroscience
73. Genetics of Alzheimer’s disease: where we are, and where we are going
    Bellenguez, Céline, Grenier-Boley, Benjamin, Lambert, Jean-Charles · 2020 · Current Opinion in Neurobiology
74. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method
    Rietveld, Cornelius A., Esko, Tõnu, Davies, Gail, Pers, Tune H., Turley, Patrick, Benyamin, Beben, Chabris, Christopher F., Emilsson, Valur, Johnson, Andrew D., Lee, James J. et al. · 2014 · Proceedings of the National Academy of Sciences
75. Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease
    Johnson, Erik C. B., Dammer, Eric B., Duong, Duc M., Yin, Luming, Thambisetty, Madhav, Troncoso, Juan C., Lah, James J., Levey, Allan I., Seyfried, Nicholas T. · 2018 · Molecular Neurodegeneration
76. Untangling Genetic Risk for Alzheimer’s Disease
    Pimenova, Anna A., Raj, Towfique, Goate, Alison M. · 2018 · Biological Psychiatry
77. Cellular and pathological heterogeneity of primary tauopathies
    Dah‐eun Chloe Chung, Shanu Faerch Roemer, Leonard Petrucelli, Dennis W. Dickson · 2021 · Molecular Neurodegeneration
78. Inflammatory Cytokines and Alzheimer’s Disease: A Review from the Perspective of Genetic Polymorphisms
    Su, Fan, Bai, Feng, Zhang, Zhijun · 2016 · Neuroscience Bulletin
79. Peripheral immune system in aging and Alzheimer’s disease
    Cao, Wei, Zheng, Hui · 2018 · Molecular Neurodegeneration
80. Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors
    Van Acker, Zoë P., Bretou, Marine, Annaert, Wim · 2019 · Molecular Neurodegeneration
81. A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics
    Qiongshi Lu, Boyang Li, Derek Ou, Margret Erlendsdottir, Ryan L. Powles, Tony Jiang, Yiming Hu, David Chang, Chentian Jin, Wei Dai et al. · 2017 · The American Journal of Human Genetics
82. WNT Signaling in Disease
    NG Li, Prameet Kaur, Nawat Bunnag, Jahnavi Suresh, Isabelle Chiao Han Sung, Qian Hui Tan, Jan Gruber, Nicholas S. Tolwinski · 2019 · Cells
83. Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer’s Disease
    Lewcock, Joseph W., Schlepckow, Kai, Di Paolo, Gilbert, Tahirovic, Sabina, Monroe, Kathryn M., Haass, Christian · 2020 · Neuron
84. Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer’s disease
    Morris, Gary P., Clark, Ian A., Vissel, Bryce · 2018 · Acta Neuropathologica
85. Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
    Migliore, Lucia, Coppedè, Fabio · 2022 · Nature Reviews Neurology
86. Review of Current Strategies for Delivering Alzheimer’s Disease Drugs across the Blood-Brain Barrier
    Ka Hong Wong, Muhammad Kashif Riaz, Yuning Xie, Xue Zhang, Qiang Liu, Huoji Chen, Zhaoxiang Bian, Xiaoyu Chen, Aiping Lü, Zhijun Yang · 2019 · International Journal of Molecular Sciences
87. Blood–Brain Barrier Breakdown in Alzheimer’s Disease: Mechanisms and Targeted Strategies
    Alkhalifa, Amer E., Al-Ghraiybah, Nour F., Odum, Julia, Shunnarah, John G., Austin, Nataleigh, Kaddoumi, Amal · 2023 · International Journal of Molecular Sciences
88. The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics
    De Roeck, Arne, Van Broeckhoven, Christine, Sleegers, Kristel · 2019 · Acta Neuropathologica
89. Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer’s Disease Genetics
    Podleśny-Drabiniok, Anna, Marcora, Edoardo, Goate, Alison M. · 2020 · Trends in Neurosciences
90. Transcriptional and epigenetic decoding of the microglial aging process
    Xiaoyu Li, Yuxin Li, Yuxiao Jin, Yuheng Zhang, Jingchuan Wu, Zhen Xu, Yubin Huang, Lin Cai, Shuai Gao, Taohui Liu et al. · 2023 · Nature Aging
91. HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework
    Erdem Varol, Aristeidis Sotiras, Christos A. Davatzikos · 2016 · NeuroImage
92. Genetics of Alzheimer’s Disease
    Vincent Antoine Chouraki, Sudha S. Seshadri · 2014 · Advances in genetics
93. Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain
    Devon S. Svoboda, M. Inmaculada Barrasa, Jian Shu, Rosalie G. J. Rietjens, Shupei Zhang, Maya Mitalipova, Peter Berube, Dongdong Fu, Leonard D. Shultz, George W. Bell et al. · 2019 · Proceedings of the National Academy of Sciences
94. The role of <i>TREM2</i> R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease
    Lill, Christina M., Rengmark, Aina, Pihlstrøm, Lasse, Fogh, Isabella, Shatunov, Aleksey, Sleiman, Patrick M., Wang, Li‐San, Liu, Tian, Lassen, Christina F., Meissner, Esther et al. · 2015 · Alzheimer's &amp; Dementia
95. Noncoding RNAs in Alzheimer's disease
    Maria Laura Idda, Rachel B. Munk, Kotb Abdelmohsen, Myriam Gorospe · 2018 · Wiley Interdisciplinary Reviews - RNA
96. Harnessing genetic complexity to enhance translatability of Alzheimer’s disease mouse models: A path toward precision medicine
    Neuner, Sarah M., Heuer, Sarah E., Huentelman, Matthew J., O’Connell, Kristen M.S., Kaczorowski, Catherine C. · 2019 · Neuron
97. The Alzheimer's Disease Sequencing Project: Study design and sample selection
    Beecham, Gary W., Bis, J.C., Martin, E.R., Choi, S.-H., DeStefano, A. L., van Duijn, C.M., Fornage, M., Gabriel, S.B., Koboldt, D.C., Larson, D.E. et al. · 2017 · Neurology Genetics
98. Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System
    Sarah M. Carpanini, Megan Torvell, B. Paul Morgan · 2019 · Frontiers in Immunology
99. Adult Hippocampal Neurogenesis in Major Depressive Disorder and Alzheimer's Disease.
    Thomas Berger, Hyunah Lee, A. Young, D. Aarsland, S. Thuret · 2020 · Trends in Molecular Medicine
100. Improving and Accelerating Drug Development for Nervous System Disorders
     Diana E. Pankevich, Bruce M. Altevogt, John Dunlop, Fred H. Gage, Steve Hyman · 2014 · Neuron