Canalization of development by microRNAs

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292 · see citing works

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

WADDINGTON, C. H. (1942) · Nature · doi:10.1038/150563a0 · Cited by 3,255 · see citing works

Hsp90 as a capacitor for morphological evolution

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Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

Xie, X., Lu, J., Kulbokas, E. J., Golub, T. R., Mootha, V., Lindblad-Toh, K., Lander, E. S., & Kellis, M. (2005) · Nature · doi:10.1038/nature03441 · Cited by 1,872 · see citing works

The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution

Farh, K. K.-H., Grimson, A., Jan, C., Lewis, B. P., Johnston, W. K., Lim, L. P., Burge, C. B., & Bartel, D. P. (2005) · Science · doi:10.1126/science.1121158 · Cited by 1,484 · see citing works

Intrinsic noise in gene regulatory networks

Thattai, M., & van Oudenaarden, A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.151588598 · Cited by 1,428 · see citing works

Animal MicroRNAs Confer Robustness to Gene Expression and Have a Significant Impact on 3′UTR Evolution

Stark, A., Brennecke, J., Bushati, N., Russell, R. B., & Cohen, S. M. (2005) · Cell · doi:10.1016/j.cell.2005.11.023 · Cited by 1,080 · see citing works

Uncovering cryptic genetic variation

Gibson, G., & Dworkin, I. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1426 · Cited by 546 · see citing works

MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision

Johnston, R. J., Chang, S., Etchberger, J. F., Ortiz, C. O., & Hobert, O. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505530102 · Cited by 276 · see citing works

Network motifs: theory and experimental approaches

Alon, U. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2102 · Cited by 3,279 · see citing works

The evolution of gene regulation by transcription factors and microRNAs

Chen, K., & Rajewsky, N. (2007) · Nature Reviews Genetics · doi:10.1038/nrg1990 · Cited by 1,547 · see citing works

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

Karayiorgou, M., Simon, T. J., & Gogos, J. A. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2841 · Cited by 474 · see citing works

MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system

Kapsimali, M., Kloosterman, W. P., de Bruijn, E., Rosa, F., Plasterk, R. H., & Wilson, S. W. (2007) · Genome Biology · doi:10.1186/gb-2007-8-8-r173 · Cited by 376 · see citing works

MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion

Peterson, K. J., Dietrich, M. R., & McPeek, M. A. (2009) · BioEssays · doi:10.1002/bies.200900033 · Cited by 252 · see citing works

Identification of Dynamically Regulated MicroRNA and mRNA Networks in Developing Oligodendrocytes

Lau, P., Verrier, J. D., Nielsen, J. A., Johnson, K. R., Notterpek, L., & Hudson, L. D. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1932-08.2008 · Cited by 252 · see citing works

A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation

Rosa, A., & Brivanlou, A. H. (2011) · The EMBO Journal · doi:10.1038/emboj.2010.319 · Cited by 198 · see citing works

The evolution of associative learning: A factor in the Cambrian explosion

Ginsburg, S., & Jablonka, E. (2010) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2010.06.017 · Cited by 184 · see citing works

MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise

Siciliano, V., Garzilli, I., Fracassi, C., Criscuolo, S., Ventre, S., & di Bernardo, D. (2013) · Nature Communications · doi:10.1038/ncomms3364 · Cited by 166 · see citing works

The Utility of Paradoxical Components in Biological Circuits

Hart, Y., & Alon, U. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.01.004 · Cited by 151 · see citing works

Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health

Davey Smith, G. (2011) · Genes & Nutrition · doi:10.1007/s12263-010-0181-y · Cited by 134 · see citing works

An Lmx1b–miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool

Anderegg, A., Lin, H.-P., Chen, J.-A., Caronia-Brown, G., Cherepanova, N., Yun, B., Joksimovic, M., Rock, J., Harfe, B. D., Johnson, R., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003973 · Cited by 57 · see citing works

Gestation under chronic constant light leads to extensive gene expression changes in the fetal rat liver

Spichiger, C., Torres-Farfan, C., Galdames, H. A., Mendez, N., Alonso-Vazquez, P., & Richter, H. G. (2015) · Physiological Genomics · doi:10.1152/physiolgenomics.00023.2015 · Cited by 34 · see citing works

Exact distributions of threshold crossing times of proteins under post-transcriptional regulation by small RNAs

Ali, S. Y., Prasad, A., & Das, D. (2025) · Physical Review E · doi:10.1103/physreve.111.014405 · Cited by 2 · see citing works