Immune cell migration in inflammation: present and future therapeutic targets

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

Springer, T. A. (1994) · Cell · doi:10.1016/0092-8674(94)90337-9 · Cited by 7,009

Immunobiology of Dendritic Cells

Banchereau, J., Brière, F., Caux, C., Davoust, J. M., Lebecque, S., Liu, Y., Pulendran, B., & Palucka, K. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.767 · Cited by 6,755

Chemokines — Chemotactic Cytokines That Mediate Inflammation

Luster, A. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802123380706 · Cited by 3,633

Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504

Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

Sallusto, F., Geginat, J., & Lanzavecchia, A. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104702 · Cited by 3,067

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

Butcher, E. C. (1991) · Cell · doi:10.1016/0092-8674(91)90279-8 · Cited by 2,789

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

Matloubian, M., Lo, C. G., Cinamon, G., Lesneski, M. J., Xu, Y., Brinkmann, V., Allende, M. L., Proia, R. L., & Cyster, J. G. (2004) · Nature · doi:10.1038/nature02284 · Cited by 2,581

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

Boring, L., Gosling, J., Cleary, M., & Charo, I. F. (1998) · Nature · doi:10.1038/29788 · Cited by 1,965

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.

Jung, S., Unutmaz, D., Wong, P., Sano, G., Santos, K. D. L., Sparwasser, T., Wu, S., Vuthoori, S., Ko, K., Zavala, F., et al. (2002) · Immunity · doi:10.1016/s1074-7613(02)00365-5 · Cited by 1,953

Lineage relationship and protective immunity of memory CD8 T cell subsets

Wherry, E. J., Teichgräber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H., & Ahmed, R. (2003) · Nature Immunology · doi:10.1038/ni889 · Cited by 1,864

Key concepts in immunology

Moser, M., & Léo, O. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.07.022 · Cited by 216

Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns

Sebzda, E., Zou, Z., Lee, J. S., Wang, T., & Kahn, M. L. (2008) · Nature Immunology · doi:10.1038/ni1565 · Cited by 207

Radiobiological mechanisms in inflammatory diseases of low-dose radiation therapy

Rödel, F., Keilholz, L., i, M. H., Sauer, R., & Hildebrandt, G. (2007) · International Journal of Radiation Biology · doi:10.1080/09553000701317358 · Cited by 210

Radiation, Inflammation, and Immune Responses in Cancer

Multhoff, G., & Radons, J. (2012) · Frontiers in Oncology · doi:10.3389/fonc.2012.00058 · Cited by 206

Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19

Alon, R., Sportiello, M., Kozlovski, S., Kumar, A., Reilly, E. C., Zarbock, A., Garbi, N., & Topham, D. J. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-020-00470-2 · Cited by 197

Oncolytic virotherapy: Molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic viruses

Guo, Z. S., Thorne, S. H., & Bartlett, D. L. (2008) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2008.02.001 · Cited by 198

CCL2/MCP-1 modulation of microglial activation and proliferation

Hinojosa, A. E., García‐Bueno, B., Leza, J. C., & Madrigal, J. L. M. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-77 · Cited by 200

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

Balenga, N. A. B., Aflaki, E., Kargl, J., Platzer, W., Schröder, R. J., Blättermann, S., Kostenis, E., Brown, A. J., Heinemann, Á., & Waldhoer, M. (2011) · Cell Research · doi:10.1038/cr.2011.60 · Cited by 197

CD103 or LFA-1 Engagement at the Immune Synapse between Cytotoxic T Cells and Tumor Cells Promotes Maturation and Regulates T-cell Effector Functions

Franciszkiewicz, K., Floc’h, A. L., Boutet, M., Vergnon, I., Schmitt, A., & Mami‐Chouaib, F. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-2569 · Cited by 189

Spiegelmer Inhibition of CCL2/MCP-1 Ameliorates Lupus Nephritis in MRL-(Fas)lpr Mice

Kulkarni, O. P., Pawar, R. D., Purschke, W. G., Eulberg, D., Selve, N., Buchner, K., Ninichuk, V., Segerer, S., Vielhauer, V., Klußmann, S., et al. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006121348 · Cited by 188

The Pancreatic Cancer Microenvironment

Dougan, S. K. (2017) · The Cancer Journal · doi:10.1097/ppo.0000000000000288 · Cited by 193

Corneal Pain without Stain: Is it Real?

Rosenthal, P., Baran, I., & Jacobs, D. S. (2009) · The Ocular Surface · doi:10.1016/s1542-0124(12)70290-2 · Cited by 184

Myeloid Cells in the Tumor Microenvironment: Modulation of Tumor Angiogenesis and Tumor Inflammation

Schmid, M. C., & Varner, J. A. (2010) · Journal of Oncology · doi:10.1155/2010/201026 · Cited by 191

Tissue-tropic effector T cells: generation and targeting opportunities

Agace, W. W. (2006) · Nature reviews. Immunology · doi:10.1038/nri1869 · Cited by 186

Immune cell entry into the central nervous system: Involvement of adhesion molecules and chemokines

Engelhardt, B. (2008) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2008.05.019 · Cited by 179

Why Integrin as a Primary Target for Imaging and Therapy

Niu, G., & Chen, X. S. (2011) · Theranostics · doi:10.7150/thno/v01p0030 · Cited by 187

Design Strategies and Applications of Circulating Cell-Mediated Drug Delivery Systems

Su, Y., Xie, Z., Kim, G. B., Dong, C., & Yang, J. Y. (2015) · ACS Biomaterials Science & Engineering · doi:10.1021/ab500179h · Cited by 180

An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues

Chakraverty, R. K., Côté, D. C., Buchli, J., Cotter, P., Hsu, R., Zhao, G., Sachs, T. E., Pitsillides, C. M., Bronson, R. T., Means, T. K., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060376 · Cited by 178

Chemotactic Activity of S100A7 (Psoriasin) Is Mediated by the Receptor for Advanced Glycation End Products and Potentiates Inflammation with Highly Homologous but Functionally Distinct S100A15

Wolf, R., Howard, O. M. Z., Dong, H., Voscopoulos, C. J., Boeshans, K. M., Winston, J., Divi, R. L., Gunsior, M., Goldsmith, P., Ahvazi, B., et al. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.2.1499 · Cited by 178

Stem-cell ecology and stem cells in motion

Papayannopoulou, T., & Scadden, D. T. (2008) · Blood · doi:10.1182/blood-2007-08-078147 · Cited by 173

Role of high mobility group box 1 in inflammatory disease: Focus on sepsis

Bae, J. (2012) · Archives of Pharmacal Research · doi:10.1007/s12272-012-0901-5 · Cited by 174

Therapeutic approaches targeting inflammation for diabetes and associated cardiovascular risk

Goldfine, A. B., & Shoelson, S. E. (2017) · Journal of Clinical Investigation · doi:10.1172/jci88884 · Cited by 176

Allergen Induces the Migration of Platelets to Lung Tissue in Allergic Asthma

Pitchford, S. C., Momi, S., Baglioni, S., Casali, L., Giannini, S., Rossi, R., Page, C. P., & Gresele, P. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200702-214oc · Cited by 169

Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte–endothelial interactions

Rossi, B., Angiari, S., Zenaro, E., Budui, S. L., & Constantin, G. (2010) · Journal of Leukocyte Biology · doi:10.1189/jlb.0710432 · Cited by 172

The multiple faces of leukocyte interstitial migration

Lämmermann, T., & Germain, R. N. (2014) · Seminars in Immunopathology · doi:10.1007/s00281-014-0418-8 · Cited by 177

The Role of Neutrophils and Monocytes in Innate Immunity

Kantari‐Mimoun, C., Pederzoli-Ribeil, M., & Witko‐Sarsat, V. (2008) · KARGER eBooks · doi:10.1159/000136335 · Cited by 177

Endosomal signalling via exosome surface TGFβ‐1

Shelke, G. V., Yin, Y., Jang, S. C., Lässer, C., Wennmalm, S., Hoffmann, H. J., Li, L., Gho, Y. S., Nilsson, J. A., & Lötvall, J. O. (2019) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2019.1650458 · Cited by 175

Molecular Pathways: VCAM-1 as a Potential Therapeutic Target in Metastasis

Chen, Q., & Massagué, J. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-2904 · Cited by 170

Biopsy-induced inflammatory conditions improve endometrial receptivity: the mechanism of action

Gnainsky, Y., Granot, I., Aldo, P. B., Бараш, А. Н., Or, Y., Mor, G., & Dekel, N. (2014) · Reproduction · doi:10.1530/rep-14-0395 · Cited by 163

NK Cells Stimulate Recruitment of CXCR3+ T Cells to the Brain during Plasmodium berghei -Mediated Cerebral Malaria

Hansen, D. S., Bernard, N. J., Nie, C. Q., & Schofield, L. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.9.5779 · Cited by 162

Chemokines in colon cancer progression

Jia, S., Han, Y.-B., Yang, R., & Yang, Z. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.02.007 · Cited by 161

Immunological Aspects of Approved MS Therapeutics

Rommer, P. S., Milo, R., Han, M. H., Satyanarayan, S., Sellner, J., Hauer, L., Illés, Z., Warnke, C., Laurent, S. A., Weber, M. S., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01564 · Cited by 161

Purinergic P2X4 receptors and mitochondrial ATP production regulate T cell migration

Ledderose, C., Liu, K., Kondo, Y., Slubowski, C. J., Dertnig, T., Denicolò, S., Arbab, M., Hubner, J., Konrad, K., Fakhari, M., et al. (2018) · Journal of Clinical Investigation · doi:10.1172/jci120972 · Cited by 160

Natalizumab: Targeting α4-Integrins in Multiple Sclerosis

Engelhardt, B., & Kappos, L. (2007) · Neurodegenerative Diseases · doi:10.1159/000109933 · Cited by 156

Intracellular transport of Toxoplasma gondii through the blood–brain barrier

Lachenmaier, S., Deli, M. A., Meissner, M., & Liesenfeld, O. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.10.029 · Cited by 159

A key role for G-CSF–induced neutrophil production and trafficking during inflammatory arthritis

Eyles, J. L., Hickey, M. J., Norman, M. U., Croker, B. A., Roberts, A. W., Drake, S. F., James, W. G., Metcalf, D., Campbell, I. K., & Wicks, I. P. (2008) · Blood · doi:10.1182/blood-2008-02-139535 · Cited by 154

MIF Promotes B Cell Chemotaxis through the Receptors CXCR4 and CD74 and ZAP-70 Signaling

Klasen, C., Ohl, K., Sternkopf, M., Shachar, I., Schmitz, C., Heussen, N. M., Hobeika, E., Levit‐Zerdoun, E., Tenbrock, K., Reth, M. G., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1302209 · Cited by 157

T Cell Trafficking through Lymphatic Vessels

Hunter, M. C., Teijeira, Á., & Halin, C. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00613 · Cited by 162

The pathogenic role of tissue-resident immune cells in psoriasis

Boyman, O., Conrad, C., Tonel, G., Gilliet, M., & Nestle, F. O. (2007) · Trends in Immunology · doi:10.1016/j.it.2006.12.005 · Cited by 151

Gut‐associated lymphoid tissue, T cell trafficking, and chronic intestinal inflammation

Koboziev, I., Karlsson, F. J., & Grisham, M. B. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05711.x · Cited by 150

Mechanisms of force generation and force transmission during interstitial leukocyte migration

Renkawitz, J., & Sixt, M. (2010) · EMBO Reports · doi:10.1038/embor.2010.147 · Cited by 145

Borneol, a Bicyclic Monoterpene Alcohol, Reduces Nociceptive Behavior and Inflammatory Response in Mice

Almeida, J. R. G. D. S., Souza, G. R., Silva, J. C., de Lima-Saraiva, S. R. G., Júnior, R. G. D. O., Quintans, J. D. S. S., Barreto, R. D. S. S., Bonjardim, L. R., Cavalcanti, S. C. H., & Quintans‐Júnior, L. J. (2013) · The Scientific World JOURNAL · doi:10.1155/2013/808460 · Cited by 145

Mutant huntingtin impairs immune cell migration in Huntington disease

Kwan, W., Träger, U., Davalos, D., Chou, A., Bouchard, J. J., André, R., Miller, A., Weiss, A., Giorgini, F., Cheah, C. S., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci64484 · Cited by 145

Microfluidic devices for studying chemotaxis and electrotaxis

Li, J., & Lin, F. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.05.002 · Cited by 144

Targeting HMGB1 in the treatment of sepsis

Wang, H., Ward, M. F., & Sama, A. E. (2014) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2014.863876 · Cited by 144

Fibrocytes in lung disease

Gomperts, B. N., & Strieter, R. M. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0906587 · Cited by 141

Dental Pulp Stem Cell Migration

Howard, C., Murray, P. E., & Namerow, K. N. (2010) · Journal of Endodontics · doi:10.1016/j.joen.2010.08.046 · Cited by 141

New Insights into the Cell Biology of Hematopoietic Progenitors by Studying Prominin-1 (CD133)

Bauer, N., Fonseca, A., Florek, M., Freund, D., Jászai, J., Bornhäuser, M., Fargeas, C. A., & Corbeil, D. (2007) · Cells Tissues Organs · doi:10.1159/000112847 · Cited by 137

Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

Cougoule, C., Cabec, V. L., Poincloux, R., Saati, T. A., Mège, J., Tabouret, G., Lowell, C. A., Laviolette‐Malirat, N., & Maridonneau‐Parini, I. (2009) · Blood · doi:10.1182/blood-2009-04-218735 · Cited by 144

Role of Tumor Endothelium in CD4+CD25+ Regulatory T Cell Infiltration of Human Pancreatic Carcinoma

Nummer, D., Suri‐Payer, E., Schmitz‐Winnenthal, H., Bonertz, A., Galindo, L., Antolovic, D., Koch, M., Büchler, M., Weitz, J., Schirrmacher, V., et al. (2007) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djm064 · Cited by 137

Engineered Models of Confined Cell Migration

Paul, C. D., Hung, W.-C., Wirtz, D., & Κωνσταντόπουλος, Κ. (2016) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071114-040654 · Cited by 134

Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors

Kim, C. H., Wu, W., Wysoczynski, M., Abdel‐Latif, A., Sunkara, M., Morris, A. J., Kucia, M., Ratajczak, J., & Ratajczak, M. Z. (2011) · Leukemia · doi:10.1038/leu.2011.185 · Cited by 132

Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on 4 integrin

Ifergan, I., Kébir, H., Alvarez, J. I., Marceau, G., Bernard, M., Bourbonnière, L., Poirier, J., Duquette, P., Talbot, P. J., Arbour, N., et al. (2011) · Brain · doi:10.1093/brain/awr268 · Cited by 136

Fingolimod and Sphingosine-1-Phosphate — Modifiers of Lymphocyte Migration

Maßberg, S., & von Andrian, U. H. (2006) · New England Journal of Medicine · doi:10.1056/nejmp068159 · Cited by 129

Endothelial TNF Receptor 2 Induces IRF1 Transcription Factor-Dependent Interferon-β Autocrine Signaling to Promote Monocyte Recruitment

Venkatesh, D., Ernandez, T., Rosetti, F., Batal, I., Culleré, X., Luscinskas, F. W., Zhang, Y., Stavrakis, G., García‐Cardeña, G., Horwitz, B. H., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.01.012 · Cited by 128

Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin–mediated human T-cell adhesion

Ghandour, H., Culleré, X., Álvarez, Á., Luscinskas, F. W., & Mayadas, T. N. (2007) · Blood · doi:10.1182/blood-2007-03-077628 · Cited by 128

Therapeutic potential of adult bone marrow‐derived mesenchymal stem cells in diseases of the skeleton

Chanda, D., Kumar, S., & Ponnazhagan, S. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22701 · Cited by 127

The microanatomy of T‐cell responses

Lämmermann, T., & Sixt, M. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00592.x · Cited by 126

TLR2 Transmodulates Monocyte Adhesion and Transmigration via Rac1- and PI3K-Mediated Inside-Out Signaling in Response to Porphyromonas gingivalis Fimbriae

Harokopakis, E., Albzreh, M. H., Martin, M. H., & Hajishengallis, G. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.12.7645 · Cited by 126

Implications of mesenchymal stem cells in regenerative medicine

Kariminekoo, S., Movassaghpour, A. A., Rahimzadeh, A., Talebi, M., Shamsasenjan, K., & Akbarzadeh, A. (2016) · Artificial Cells Nanomedicine and Biotechnology · doi:10.3109/21691401.2015.1129620 · Cited by 125

NOVEL HMGB1-INHIBITING THERAPEUTIC AGENTS FOR EXPERIMENTAL SEPSIS

Wang, H., Ward, M. F., & Sama, A. E. (2009) · Shock · doi:10.1097/shk.0b013e3181a551bd · Cited by 125

Multi-step microfluidic device for studying cancer metastasis

Chaw, K. C., Manimaran, M., Tay, E. H., & Swaminathan, S. (2007) · Lab on a Chip · doi:10.1039/b707399m · Cited by 125

Pharmacological Properties, Toxicology and Scientific Rationale for the use of Natalizumab (Tysabri®) in Inflammatory Diseases

Stüve, O., & Bennett, J. L. (2007) · CNS Drug Reviews · doi:10.1111/j.1527-3458.2007.00003.x · Cited by 123

Nuclear constriction segregates mobile nuclear proteins away from chromatin

Irianto, J., Pfeifer, C. R., Bennett, R. R., Xia, Y., Ivanovska, I. L., Liu, A. J., Greenberg, R. A., & Discher, D. E. (2016) · Molecular Biology of the Cell · doi:10.1091/mbc.e16-06-0428 · Cited by 128

Essential role of monocytes and macrophages in the progression of acute pancreatitis

Shrivastava, P. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i32.3995 · Cited by 120

Human Lymphatic Endothelial Cells Express Multiple Functional TLRs

Pegu, A., Qin, S., Junecko, B. A. F., Nisato, R. E., Pepper, M. S., & Reinhart, T. A. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.5.3399 · Cited by 120

Digital cell quantification identifies global immune cell dynamics during influenza infection

Altboum, Z., Steuerman, Y., David, E., Barnett‐Itzhaki, Z., Valadarsky, L., Keren‐Shaul, H., Meningher, T., Mendelson, E., Mandelboim, M., Gat‐Viks, I., et al. (2014) · Molecular Systems Biology · doi:10.1002/msb.134947 · Cited by 125

Quantifying Antigen-Specific CD4 T Cells during a Viral Infection: CD4 T Cell Responses Are Larger Than We Think

McDermott, D. S., & Varga, S. M. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1102104 · Cited by 119

Touch of Chemokines

Blanchet, X., Langer, M., Weber, C., Koenen, R. R., & von Hundelshausen, P. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00175 · Cited by 121

Structure–Property Correlations of Reactive Oxygen Species-Responsive and Hydrogen Peroxide-Eliminating Materials with Anti-Oxidant and Anti-Inflammatory Activities

Zhang, Q., Zhang, F., Chen, Y., Dou, Y., Tao, H., Zhang, D., Wang, R., Li, X., & Zhang, J. (2017) · Chemistry of Materials · doi:10.1021/acs.chemmater.7b02412 · Cited by 118

Ex Vivo Adenoviral Vector Gene Delivery Results in Decreased Vector-associated Inflammation Pre- and Post–lung Transplantation in the Pig

Yeung, J. C., Wagnetz, D., Cypel, M., Rubacha, M., Koike, T., Chun, Y.-M., Hu, J., Waddell, T. K., Hwang, D. M., Liu, M., et al. (2012) · Molecular Therapy · doi:10.1038/mt.2012.57 · Cited by 116

Complement and periodontitis

Hajishengallis, G. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.06.017 · Cited by 117

Natalizumab and Progressive Multifocal Leukoencephalopathy

Warnke, C., Menge, T., Hartung, H., Racke, M. K., Cravens, P. D., Bennett, J. L., Frohman, E. M., Greenberg, B. M., Zamvil, S. S., Gold, R., et al. (2010) · Archives of Neurology · doi:10.1001/archneurol.2010.161 · Cited by 115

Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model

Wu, P.-H., Giri, A., & Wirtz, D. (2015) · Nature Protocols · doi:10.1038/nprot.2015.030 · Cited by 113

Therapeutic potential of HMGB1-targeting agents in sepsis

Wang, H., Zhu, S., Zhou, R., Li, W., & Sama, A. E. (2008) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399408000884 · Cited by 115

Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice

Liu, Y., Belkina, N. V., Park, C., Nambiar, R., Loughhead, S. M., Patiño‐López, G., Ben-Aissa, K., Hao, J.-J., Kruhlak, M. J., Qi, H., et al. (2011) · Blood · doi:10.1182/blood-2011-07-368860 · Cited by 118

Glucocorticoids inhibit macrophage differentiation towards a pro-inflammatory phenotype upon wounding without affecting their migration

Xie, Y., Tolmeijer, S. H., Oskam, J. M., Tonkens, T., Meijer, A. H., & Schaaf, M. J. M. (2019) · Disease Models & Mechanisms · doi:10.1242/dmm.037887 · Cited by 114

Directions in the immune targeting of cancer: Lessons learned from the cancer‐testis Ag NY‐ESO‐1

Nicholaou, T., Ebert, L. M., Davis, I. D., Robson, N. C., Klein, O., Maraskovsky, E., Chen, W., & Cebon, J. S. (2006) · Immunology and Cell Biology · doi:10.1111/j.1440-1711.2006.01446.x · Cited by 112

19F magnetic resonance imaging of endogenous macrophages in inflammation

Temme, S., Bönner, F., Schrader, J., & Flögel, U. (2012) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1163 · Cited by 111

Cyclodextrin‐Derived Intrinsically Bioactive Nanoparticles for Treatment of Acute and Chronic Inflammatory Diseases

Guo, J., Li, D., Tao, H., Li, G., Liu, R., Dou, Y., Jin, T., Li, L., Huang, J., Hu, H., et al. (2019) · Advanced Materials · doi:10.1002/adma.201904607 · Cited by 110

Endogenous modulators of inflammatory cell recruitment

Hajishengallis, G., & Chavakis, T. (2012) · Trends in Immunology · doi:10.1016/j.it.2012.08.003 · Cited by 113

E- and P-Selectin Are Not Required for the Development of Experimental Autoimmune Encephalomyelitis in C57BL/6 and SJL Mice

Döring, A., Wild, M. K., Vestweber, D., Deutsch, U., & Engelhardt, B. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.12.8470 · Cited by 110

Stem cells as vectors for antitumour therapy

Loebinger, M. R., & Janes, S. M. (2010) · Thorax · doi:10.1136/thx.2009.128025 · Cited by 109

Innate immunity as orchestrator of stem cell mobilization

Ratajczak, M. Z., Kim, C. H., Wojakowski, W., Janowska‐Wieczorek, A., Kucia, M., & Ratajczak, J. (2010) · Leukemia · doi:10.1038/leu.2010.162 · Cited by 109

The mechanisms of pathological extramedullary hematopoiesis in diseases

Yang, X., Chen, D., Long, H., & Zhu, B. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03450-w · Cited by 114

Human variability in innate immunity

Kinane, D. F., Demuth, D. R., Gorr, S., Hajishengallis, G., & Martin, M. H. (2007) · Periodontology 2000 · doi:10.1111/j.1600-0757.2007.00220.x · Cited by 110

CD11c + Dendritic Cells Maintain Antigen Processing, Presentation Capabilities, and CD4 + T-Cell Priming Efficacy Under Hypercholesterolemic Conditions Associated With Atherosclerosis

Packard, R. R. S., Maganto-García, E., Gotsman, I., Tabas, I. A., Libby, P., & Lichtman, A. H. (2008) · Circulation Research · doi:10.1161/circresaha.108.185793 · Cited by 107

Strategies to improve homing of mesenchymal stem cells for greater efficacy in stem cell therapy

Naderi‐Meshkin, H., Bahrami, A. R., Bidkhori, H. R., Mirahmadi, M., & Ahmadiankia, N. (2014) · Cell Biology International · doi:10.1002/cbin.10378 · Cited by 106

Confined migration induces heterochromatin formation and alters chromatin accessibility

Hsia, C.-R., McAllister, J., Hasan, O., Judd, J., Lee, S. Y., Agrawal, R., Chang, C., Soloway, P. D., & Lammerding, J. (2022) · iScience · doi:10.1016/j.isci.2022.104978 · Cited by 109

A novel perspective on stem cell homing and mobilization: review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients

Ratajczak, M. Z., Kim, C. H., Abdel‐Latif, A., Schneider, G., Kucia, M., Morris, A. J., Laughlin, M. J., & Ratajczak, J. (2011) · Leukemia · doi:10.1038/leu.2011.242 · Cited by 105

Cell-mediated delivery of synthetic nano- and microparticles

Ayer, M., & Klok, H. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.01.048 · Cited by 105

Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation

Saito, E., Kuo, R., Pearson, R. M., Gohel, N., Cheung, B., King, N. J. C., Miller, S. D., & Shea, L. D. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.02.025 · Cited by 107

Exercise-induced skeletal muscle angiogenesis: impact of age, sex, angiocrines and cellular mediators

Ross, M., Kargl, C. K., Ferguson, R. A., Gavin, T. P., & Hellsten, Y. (2023) · European Journal of Applied Physiology · doi:10.1007/s00421-022-05128-6 · Cited by 116

Novel aspects in the regulation of the leukocyte adhesion cascade

Chavakis, E., Choi, E. Y., & Chavakis, T. (2009) · Thrombosis and Haemostasis · doi:10.1160/th08-12-0844 · Cited by 108

Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice

Yan, A., Liu, Z., Song, L., Wang, X., Zhang, Y., Wu, N., Lin, J., Liu, Y., & Liu, Z. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00529 · Cited by 103

Separating Smoking-Related Diseases Using NMR-Based Metabolomics of Exhaled Breath Condensate

de Laurentiis, G., Paris, D., Melck, D. J., Montuschi, P., Maniscalco, M., Bianco, A., Sofia, M., & Motta, A. (2013) · Journal of Proteome Research · doi:10.1021/pr301171p · Cited by 103

Pioglitazone Inhibits Toll-Like Receptor Expression and Activity in Human Monocytes and db/db Mice

Dasu, M. R. K., Park, S., Devaraj, S., & Jialal, I. (2007) · Endocrinology · doi:10.1210/en.2008-1757 · Cited by 103

Carteramine A, an inhibitor of neutrophil chemotaxis, from the marine sponge Stylissa carteri

Kobayashi, H., Kitamura, K., Nagai, K., Nakao, Y., Fusetani, N., van Soest, R. W. M., & Matsunaga, S. (2007) · Tetrahedron Letters · doi:10.1016/j.tetlet.2007.01.113 · Cited by 103

Mitigation of Inflammation with Foods

Wu, X., & Schauss, A. G. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf3007008 · Cited by 103

Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions

Iwaszkiewicz, K. S., Schneider, J. J., & Hua, S. (2013) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00132 · Cited by 102

Targeting cells in motion: Migrating toward improved therapies

Griffith, J. W., & Luster, A. D. (2013) · European Journal of Immunology · doi:10.1002/eji.201243183 · Cited by 34

Targeting immune cell migration as therapy for inflammatory disease: a review

Song, B., Guo, W., He, Y., Yao, X., Sun, J., & Wang, S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1650760 · Cited by 14

Editorial: Recruitment of leukocytes during resolution of inflammation

de Oliveira, V. L. S., & Struyf, S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1808267

Chemokine-Chemokine Receptor Network in Immune Cell Trafficking

Kim, C. H. (2004) · Current Drug Targets - Immune Endocrine & Metabolic Disorders · doi:10.2174/1568008043339712 · Cited by 95

Introduction for the special issue on new paradigms in leukocyte trafficking, lessons for therapeutics

Luscinskas, F. W., & Imhof, B. A. (2014) · Seminars in Immunopathology · doi:10.1007/s00281-014-0422-z