Immune cell migration in inflammation: present and future therapeutic targets

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

Springer, T. A. (1994) · Cell · doi:10.1016/0092-8674(94)90337-9 · Cited by 7,009

Immunobiology of Dendritic Cells

Banchereau, J., Brière, F., Caux, C., Davoust, J. M., Lebecque, S., Liu, Y., Pulendran, B., & Palucka, K. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.767 · Cited by 6,755

Chemokines — Chemotactic Cytokines That Mediate Inflammation

Luster, A. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802123380706 · Cited by 3,633

Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504

Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

Sallusto, F., Geginat, J., & Lanzavecchia, A. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104702 · Cited by 3,067

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

Butcher, E. C. (1991) · Cell · doi:10.1016/0092-8674(91)90279-8 · Cited by 2,789

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

Matloubian, M., Lo, C. G., Cinamon, G., Lesneski, M. J., Xu, Y., Brinkmann, V., Allende, M. L., Proia, R. L., & Cyster, J. G. (2004) · Nature · doi:10.1038/nature02284 · Cited by 2,581

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

Boring, L., Gosling, J., Cleary, M., & Charo, I. F. (1998) · Nature · doi:10.1038/29788 · Cited by 1,965

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.

Jung, S., Unutmaz, D., Wong, P., Sano, G., Santos, K. D. L., Sparwasser, T., Wu, S., Vuthoori, S., Ko, K., Zavala, F., et al. (2002) · Immunity · doi:10.1016/s1074-7613(02)00365-5 · Cited by 1,953

Lineage relationship and protective immunity of memory CD8 T cell subsets

Wherry, E. J., Teichgräber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H., & Ahmed, R. (2003) · Nature Immunology · doi:10.1038/ni889 · Cited by 1,864

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

Serhan, C. N., Chiang, N., & Van Dyke, T. E. (2008) · Nature Reviews Immunology · doi:10.1038/nri2294 · Cited by 2,932

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

Swirski, F. K., Nahrendorf, M., Etzrodt, M., Wildgruber, M., Cortez-Retamozo, V., Panizzi, P., Figueiredo, J.-L., Kohler, R. H., Chudnovskiy, A., Waterman, P., et al. (2009) · Science · doi:10.1126/science.1175202 · Cited by 2,221

A cytokine-mediated link between innate immunity, inflammation, and cancer

Lin, W.-W., & Karin, M. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31537 · Cited by 1,940

Inflammatory bowel disease

Kaser, A., Zeissig, S., & Blumberg, R. S. (2010) · Annual Review of Immunology · doi:10.1146/annurev-immunol-030409-101225 · Cited by 1,806

Regulation of inflammation by short chain fatty acids

Vinolo, M. A. R., Rodrigues, H. G., Nachbar, R. T., & Curi, R. (2011) · Nutrients · doi:10.3390/nu3100858 · Cited by 1,724

Skin immune sentinels in health and disease

Nestle, F. O., Meglio, P. D., Qin, J., & Nickoloff, B. J. (2009) · Nature reviews. Immunology · doi:10.1038/nri2622 · Cited by 1,529

Phenotypic Heterogeneity of the Endothelium

Aird, W. C. (2007) · Circulation Research · doi:10.1161/01.res.0000255690.03436.ae · Cited by 1,288

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease

Brochard, V., Combadière, B., Prigent, A., Laouar, Y., Perrin, A., Beray-Berthat, V., Bonduelle, O., Alvarez-Fischer, D., Callebert, J., Launay, J.-M., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36470 · Cited by 1,172

History of myeloid-derived suppressor cells

Talmadge, J. E., & Gabrilovich, D. I. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3581 · Cited by 1,148

Inflammation and pregnancy: the role of the immune system at the implantation site

Mor, G., Cardenas, I., Abrahams, V. M., & Guller, S. M. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05938.x · Cited by 1,111

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

Ajami, B., Bennett, J. L., Krieger, C., McNagny, K. M., & Rossi, F. M. V. (2011) · Nature Neuroscience · doi:10.1038/nn.2887 · Cited by 1,061

Functionally specialized junctions between endothelial cells of lymphatic vessels

Baluk, P., Fuxe, J., Hashizume, H., Romano, T., Lashnits, E., Butz, S., Vestweber, D., Corada, M., Molendini, C., Dejana, E., et al. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20062596 · Cited by 1,006

Inflammation in Atherosclerosis: From Vascular Biology to Biomarker Discovery and Risk Prediction

Packard, R. R. S., & Libby, P. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.097360 · Cited by 925

Mesenchymal Stromal Cells: Current Understanding and Clinical Status

Salem, H. K., & Thiemermann, C. (2009) · Stem Cells · doi:10.1002/stem.269 · Cited by 935

Regulation of Actin Assembly Associated With Protrusion and Adhesion in Cell Migration

Clainche, C. L., & Carlier, M. (2008) · Physiological Reviews · doi:10.1152/physrev.00021.2007 · Cited by 903

Vascular Adhesion Molecules in Atherosclerosis

Galkina, E., & Ley, K. F. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.149179 · Cited by 831

Immunobiology of mesenchymal stem cells

Ma, S., Xie, N., Li, W., Yuan, B., Shi, Y., & Wang, Y. (2013) · Cell Death and Differentiation · doi:10.1038/cdd.2013.158 · Cited by 789

Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing

Yagi, H., Soto–Gutiérrez, A., Parekkadan, B., Kitagawa, Y., Tompkins, R. G., Kobayashi, N., & Yarmush, M. L. (2010) · Cell Transplantation · doi:10.3727/096368910x508762 · Cited by 717

How mesenchymal stem cells interact with tissue immune responses

Shi, Y., Su, J., Roberts, A. I., Shou, P., Rabson, A. B., & Ren, G. (2012) · Trends in Immunology · doi:10.1016/j.it.2011.11.004 · Cited by 637

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

Winkles, J. A. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2488 · Cited by 610

Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells

Spaeth, E., Klopp, A., Dembinski, J., Andreeff, M., & Marini, F. (2008) · Gene Therapy · doi:10.1038/gt.2008.39 · Cited by 579

Preferential recruitment of interferon‐γ–expressing T H 17 cells in multiple sclerosis

Kebir, H., Ifergan, I., Alvarez, J. I., Bernard, M., Poirier, J., Arbour, N., Duquette, P., & Prat, A. (2009) · Annals of Neurology · doi:10.1002/ana.21748 · Cited by 551

Design of therapeutic biomaterials to control inflammation

Tu, Z., Zhong, Y., Hu, H., Shao, D., Haag, R., Schirner, M., Lee, J., Sullenger, B. A., & Leong, K. W. (2022) · Nature Reviews Materials · doi:10.1038/s41578-022-00426-z · Cited by 533

Protection of the Neonate by the Innate Immune System of Developing Gut and of Human Milk

Newburg, D. S., & Walker, W. A. (2007) · Pediatric Research · doi:10.1203/01.pdr.0000250274.68571.18 · Cited by 524

A role for leukocyte-endothelial adhesion mechanisms in epilepsy

Fabene, P. F., Mora, G. N., Martinello, M., Rossi, B., Merigo, F., Ottoboni, L., Bach, S., Angiari, S., Benati, D., Chakir, A., et al. (2008) · Nature Medicine · doi:10.1038/nm.1878 · Cited by 520

The Use of Alternative Strategies for Enhanced Nanoparticle Delivery to Solid Tumors

Izci, M., Maksoudian, C., Manshian, B. B., & Soenen, S. J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00779 · Cited by 506

Secondary bile acids and short chain fatty acids in the colon: a focus on colonic microbiome, cell proliferation, inflammation, and cancer

Zeng, H., Umar, S., Rust, B., Lazarova, D., & Bordonaro, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051214 · Cited by 480

Current Advances in Immunomodulatory Biomaterials for Bone Regeneration

Lee, J., Byun, H., Perikamana, S. K. M., Lee, S., & Shin, H. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201801106 · Cited by 467

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs

Stark, K., Eckart, A., Haidari, S., Tirniceriu, A., Lorenz, M., von Brühl, M.-L., Gärtner, F., Khandoga, A. G., Legate, K. R., Pless, R., et al. (2013) · Nature Immunology · doi:10.1038/ni.2477 · Cited by 447

Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system

Cayrol, R., Wosik, K., Berard, J. L., Dodelet-Devillers, A., Ifergan, I., Kebir, H., Haqqani, A. S., Kreymborg, K., Krug, S., Moumdjian, R., et al. (2008) · Nature Immunology · doi:10.1038/ni1551 · Cited by 444

The role of tenascin-C in tissue injury and tumorigenesis

Midwood, K. S., & Orend, G. (2009) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-009-0075-1 · Cited by 453

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

Eskan, M. A., Jotwani, R., Abe, T., Chmelar, J., Lim, J.-H., Liang, S., Ciero, P. A., Krauss, J. L., Li, F., Rauner, M., et al. (2012) · Nature Immunology · doi:10.1038/ni.2260 · Cited by 429

Endogenous pro‐resolving and anti‐inflammatory lipid mediators: a new pharmacologic genus

Serhan, C. N., & Chiang, N. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707489 · Cited by 441

Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration

Zhu, Y., Liang, H., Liu, X., Wu, J., Cao, Y., Wong, T. M., Kwan, K. Y.-H., Cheung, K., Wu, S., & Yeung, K. (2021) · Science Advances · doi:10.1126/sciadv.abf6654 · Cited by 418

Migration of Zebrafish Primordial Germ Cells: A Role for Myosin Contraction and Cytoplasmic Flow

Blaser, H., Reichman‐Fried, M., Castanon, I., Dumstrei, K., Marlow, F. L., Kawakami, K., Solnica‐Krezel, L., Heisenberg, C., & Raz, E. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.09.023 · Cited by 406

Local injury of the endometrium induces an inflammatory response that promotes successful implantation

Gnainsky, Y., Granot, I., Aldo, P. B., Barash, A., Or, Y., Schechtman, E., Mor, G., & Dekel, N. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.02.022 · Cited by 385

Homing of endogenous stem/progenitor cells for in situ tissue regeneration: Promises, strategies, and translational perspectives

Chen, F., Wu, L., Zhang, M., Zhang, R., & Sun, H. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2010.12.032 · Cited by 387

Resolvins and protectins in the termination program of acute inflammation

Ariel, A., & Serhan, C. N. (2007) · Trends in Immunology · doi:10.1016/j.it.2007.02.007 · Cited by 386

Neutrophil trails guide influenza-specific CD8 + T cells in the airways

Lim, K., Hyun, Y., Emo, K. L., Capece, T., Bae, S., Miller, R., Topham, D. J., & Kim, M. (2015) · Science · doi:10.1126/science.aaa4352 · Cited by 372

Trafficking and differentiation of mesenchymal stem cells

Liu, Z., Zhuge, Y., & Velazquez, O. C. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22091 · Cited by 381

Mechanisms of Rejection: Current Perspectives

Wood, K. J., & Goto, R. (2012) · Transplantation · doi:10.1097/tp.0b013e31823cab44 · Cited by 369

Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression

Ariel, A., Fredman, G., Sun, Y., Kantarcı, A., Dyke, T. E. V., Luster, A. D., & Serhan, C. N. (2006) · Nature Immunology · doi:10.1038/ni1392 · Cited by 363

Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance

Tabata, M., Kadomatsu, T., Fukuhara, S., Miyata, K., Ito, Y., Endo, M., Urano, T., Zhu, H. J., Tsukano, H., Tazume, H., et al. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.08.003 · Cited by 367

Biomedical Micro‐/Nanomotors: From Overcoming Biological Barriers to In Vivo Imaging

Gao, C., Wang, Y., Ye, Z., Lin, Z., Ma, X., & He, Q. Z. (2020) · Advanced Materials · doi:10.1002/adma.202000512 · Cited by 363

Crosstalk between cancer and immune cells: Role of tumor‐associated macrophages in the tumor microenvironment

Wang, J., Li, D., Cang, H., & Guo, B. (2019) · Cancer Medicine · doi:10.1002/cam4.2327 · Cited by 363

An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium

Johnson, L. A., Clasper, S., Holt, A. P., Lalor, P. F., Baban, D., & Jackson, D. G. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20051759 · Cited by 346

Leukocyte – endothelial interactions in inflammation

Langer, H. F., & Chavakis, T. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00811.x · Cited by 355

From oxidative stress to inflammation: redox balance and immune system

Lauridsen, C. (2018) · Poultry Science · doi:10.3382/ps/pey407 · Cited by 354

Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis

Chou, R. C., Kim, N. D., Sadik, C. D., Seung, E., Lan, Y., Byrne, M. H., Haribabu, B., Iwakura, Y., & Luster, A. D. (2010) · Immunity · doi:10.1016/j.immuni.2010.07.018 · Cited by 342

Inflammatory bowel disease

Teitelbaum, D. H., & Coran, A. G. (2006) · CRC Press eBooks · doi:10.1201/b13237-67 · Cited by 341

PET/MRI of Inflammation in Myocardial Infarction

Lee, W. W., Marinelli, B. S., van der Laan, A. M., Sena, B. F., Gorbatov, R., Leuschner, F., Dutta, P., Iwamoto, Y., Ueno, T., Begieneman, M. P. V., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.08.066 · Cited by 349

Disruption of central nervous system barriers in multiple sclerosis

Alvarez, J. I., Cayrol, R., & Prat, A. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.06.017 · Cited by 334

Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking

Sigmundsdóttir, H., & Butcher, E. C. (2008) · Nature Immunology · doi:10.1038/ni.f.208 · Cited by 330

Homing and engraftment of progenitor cells: A prerequisite for cell therapy

Chavakis, E., Urbich, C., & Dimmeler, S. (2008) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2008.01.004 · Cited by 320

Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment

Choi, E. Y., Chavakis, E., Czabanka, M., Langer, H. F., Fraemohs, L., Economopoulou, M., Kundu, R. K., Orlandi, A., Zheng, Y. Y., Prieto, D. A., et al. (2008) · Science · doi:10.1126/science.1165218 · Cited by 319

Intestinal barrier dysfunction orchestrates the onset of inflammatory host–microbiome cross-talk in a human gut inflammation-on-a-chip

Shin, W., & Kim, H. J. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1810819115 · Cited by 313

Three-dimensional cell migration does not follow a random walk

Wu, P.-H., Giri, A., Sun, S. X., & Wirtz, D. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1318967111 · Cited by 312

Leukocyte Trafficking to the Small Intestine and Colon

Habtezion, A., Nguyen, L. P., Hadeiba, H., & Butcher, E. C. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.10.046 · Cited by 312

The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease

Morris, G., Berk, M., Carvalho, A. F., Caso, J. R., Sanz, Y., Walder, K. R., & Maes, M. H. J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0004-2 · Cited by 318

REVIEW ARTICLE: Inflammation and Implantation

Dekel, N., Gnainsky, Y., Granot, I., & Mor, G. (2009) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2009.00792.x · Cited by 303

Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

Dufton, N., Hannon, R., Brancaleone, V., Dalli, J., Patel, H., Gray, M., D’Acquisto, F., Buckingham, J. C., Perretti, M., & Flower, R. J. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903526 · Cited by 298

Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood–Brain Barrier Endothelium

Steiner, O., Coisne, C., Cecchelli, R., Boscacci, R., Deutsch, U., Engelhardt, B., & Lyck, R. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903732 · Cited by 293

Role of β7 Integrins in Intestinal Lymphocyte Homing and Retention

Gorfu, G., Rivera-Nieves, J., & Ley, K. (2009) · Current Molecular Medicine · doi:10.2174/156652409789105525 · Cited by 292

Ccr5 But Not Ccr1 Deficiency Reduces Development of Diet-Induced Atherosclerosis in Mice

Braunersreuther, V., Zernecke, A., Arnaud, C., Liehn, E. A., Steffens, S., Shagdarsuren, E., Bidzhekov, K., Burger, F., Pelli, G., Luckow, B., et al. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000253886.44609.ae · Cited by 296

Resident Memory T Cells (TRM) Are Abundant in Human Lung: Diversity, Function, and Antigen Specificity

Purwar, R., Campbell, J. J., Murphy, G. F., Richards, W. G., Clark, R. A., & Kupper, T. S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016245 · Cited by 286

Hyperoxia, Endothelial Progenitor Cell Mobilization, and Diabetic Wound Healing

Liu, Z., & Velazquez, O. C. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2008.2121 · Cited by 287

Dissecting How CD4 T Cells Are Lost During HIV Infection

Doitsh, G., & Greene, W. C. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.02.012 · Cited by 291

Lymphocyte Crawling and Transendothelial Migration Require Chemokine Triggering of High-Affinity LFA-1 Integrin

Shulman, Z., Shinder, V., Klein, E., Grabovsky, V., Yeger, O., Geron, E., Montresor, A., Bolomini-Vittori, M., Feigelson, S. W., Kirchhausen, T., et al. (2009) · Immunity · doi:10.1016/j.immuni.2008.12.020 · Cited by 268

Mechanisms linking dietary fiber, gut microbiota and colon cancer prevention

Zeng, H. (2014) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v6.i2.41 · Cited by 274

Macroscale biomaterials strategies for local immunomodulation

Dellacherie, M. O., Seo, B. R., & Mooney, D. J. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0106-3 · Cited by 262

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

Kanda, H., Newton, R. A., Klein, R., Morita, Y., Gunn, M. D., & Rosen, S. D. (2008) · Nature Immunology · doi:10.1038/ni1573 · Cited by 262

Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium

Miteva, D., Rutkowski, J. M., Dixon, J. B., Kilarski, W. W., Shields, J. D., & Swartz, M. A. (2010) · Circulation Research · doi:10.1161/circresaha.109.207274 · Cited by 259

Generation of gut‐homing T cells and their localization to the small intestinal mucosa

Johansson‐Lindbom, B., & Agace, W. W. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2006.00482.x · Cited by 248

Noninvasive Molecular Imaging of Neuroinflammation

Jacobs, A. H., Tavitian, B., & the INMiND consortium (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2012.53 · Cited by 245

Integrin modulation and signaling in leukocyte adhesion and migration

Rose, D. M., Alon, R., & Ginsberg, M. H. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2007.00536.x · Cited by 243

Integrin Targeted Therapeutics

Millard, M., Odde, S., & Neamati, N. (2011) · Theranostics · doi:10.7150/thno/v01p0154 · Cited by 242

Engineering Cell Membrane‐Based Nanotherapeutics to Target Inflammation

Yan, H., Shao, D., Lao, Y., Li, M., Hu, H., & Leong, K. W. (2019) · Advanced Science · doi:10.1002/advs.201900605 · Cited by 242

The Role of Inflammation for a Successful Implantation

Dekel, N., Gnainsky, Y., Granot, I., Racicot, K. E., & Mor, G. (2014) · American Journal of Reproductive Immunology · doi:10.1111/aji.12266 · Cited by 239

Tumor-related interleukins: old validated targets for new anti-cancer drug development

Setrerrahmane, S., & Xu, H. (2017) · Molecular Cancer · doi:10.1186/s12943-017-0721-9 · Cited by 245

Mechanobiology of Macrophages: How Physical Factors Coregulate Macrophage Plasticity and Phagocytosis

Jain, N., Moeller, J., & Vogel, V. (2019) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-062117-121224 · Cited by 237

Inflammatory Cell Migration into the Central Nervous System: A Few New Twists on an Old Tale

Man, S., Ubogu, E. E., & Ransohoff, R. M. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00067.x · Cited by 244

Dampening inflammation

Henson, P. M. (2005) · Nature Immunology · doi:10.1038/ni1205-1179 · Cited by 233

Regulatory T‐cell physiology and application to treat autoimmunity

Tang, Q., & Bluestone, J. A. (2006) · Immunological Reviews · doi:10.1111/j.0105-2896.2006.00421.x · Cited by 233

Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses

Tay, M. Z., Wiehe, K. J., & Pollara, J. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00332 · Cited by 242

Random migration precedes stable target cell interactions of tumor-infiltrating T cells

Mrass, P., Takano, H., Ng, L. G., Daxini, S. D., Lasaro, M. O., Iparraguirre, A., Cavanagh, L. L., von Andrian, U. H., Ertl, H. C. J., Haydon, P. G., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060710 · Cited by 228

Engineered cell homing

Sarkar, D., Spencer, J. A., Phillips, J. A., Zhao, W., Schäfer, S., Spelke, D. P., Mortensen, L. J., Ruíz, J. P., Vemula, P. K., Sridharan, R., et al. (2011) · Blood · doi:10.1182/blood-2010-10-311464 · Cited by 227

Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function

Brogdon, J. L., Xu, Y., Szabo, S. J., An, S., Buxton, F., Cohen, D., & Huang, Q. (2006) · Blood · doi:10.1182/blood-2006-04-019711 · Cited by 226

Non-genetic engineering of cells for drug delivery and cell-based therapy

Wang, Q., Cheng, H., Peng, H., Zhou, H., Li, P. Y., & Langer, R. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.12.003 · Cited by 225

T cell homing to epithelial barriers in allergic disease

Islam, S. A., & Luster, A. D. (2012) · Nature Medicine · doi:10.1038/nm.2760 · Cited by 222

CD 4+ T‐cell subsets in intestinal inflammation

Shale, M., Schiering, C., & Powrie, F. M. (2013) · Immunological Reviews · doi:10.1111/imr.12039 · Cited by 230

Endometrial inflammation and effect on implantation improvement and pregnancy outcome

Granot, I., Gnainsky, Y., & Dekel, N. (2012) · Reproduction · doi:10.1530/rep-12-0217 · Cited by 221

Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction

Leuschner, F., Panizzi, P. R., Chico‐Calero, I., Lee, W., Ueno, T., Cortez‐Retamozo, V., Waterman, P. R., Gorbatov, R., Marinelli, B. S., Iwamoto, Y., et al. (2010) · Circulation Research · doi:10.1161/circresaha.110.227454 · Cited by 226

Aptamers Against Pro- and Anti-Inflammatory Cytokines: A Review

Boshtam, M., Asgary, S., Kouhpayeh, S., Shariati, L., & Khanahmad, H. (2016) · Inflammation · doi:10.1007/s10753-016-0477-1 · Cited by 225

The molecular basis of leukocyte recruitment and its deficiencies

Schmidt, S., Moser, M., & Sperandio, M. (2012) · Molecular Immunology · doi:10.1016/j.molimm.2012.11.006 · Cited by 222

Moving targets: cell migration inhibitors as new anti-inflammatory therapies

Mackay, C. R. (2008) · Nature Immunology · doi:10.1038/ni.f.210 · Cited by 219

Cell Membrane-Coated Mimics: A Methodological Approach for Fabrication, Characterization for Therapeutic Applications, and Challenges for Clinical Translation

Chugh, V., Krishna, K. V., & Pandit, A. S. (2021) · ACS Nano · doi:10.1021/acsnano.1c03800 · Cited by 219

Real-Time Intravital Imaging of RGD−Quantum Dot Binding to Luminal Endothelium in Mouse Tumor Neovasculature

Smith, B. R., Cheng, Z., De, A., Koh, A. L., Sinclair, R., & Gambhir, S. S. (2008) · Nano Letters · doi:10.1021/nl080141f · Cited by 215

mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation

Levy, O., Zhao, W., Mortensen, L. J., LeBlanc, S., Tsang, K., Fu, M., Phillips, J. A., Sagar, V., Anandakumaran, P. N., Ngai, J., et al. (2013) · Blood · doi:10.1182/blood-2013-04-495119 · Cited by 212

CXCL12-CXCR4 Axis in Angiogenesis, Metastasis and Stem Cell Mobilization

Liekens, S., Schols, D., & Hatse, S. (2010) · Current Pharmaceutical Design · doi:10.2174/138161210794455003 · Cited by 217

Control of inflammatory responses by ceramide, sphingosine 1-phosphate and ceramide 1-phosphate

Gómez‐Muñoz, A., Presa, N., Gómez-Larrauri, A., Rivera, I.-G., Trueba, M., & Ordoñez, M. (2015) · Progress in Lipid Research · doi:10.1016/j.plipres.2015.09.002 · Cited by 220

Targeting cells in motion: Migrating toward improved therapies

Griffith, J. W., & Luster, A. D. (2013) · European Journal of Immunology · doi:10.1002/eji.201243183 · Cited by 34

Targeting immune cell migration as therapy for inflammatory disease: a review

Song, B., Guo, W., He, Y., Yao, X., Sun, J., & Wang, S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1650760 · Cited by 14

Editorial: Recruitment of leukocytes during resolution of inflammation

de Oliveira, V. L. S., & Struyf, S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1808267

Chemokine-Chemokine Receptor Network in Immune Cell Trafficking

Kim, C. H. (2004) · Current Drug Targets - Immune Endocrine & Metabolic Disorders · doi:10.2174/1568008043339712 · Cited by 95

Introduction for the special issue on new paradigms in leukocyte trafficking, lessons for therapeutics

Luscinskas, F. W., & Imhof, B. A. (2014) · Seminars in Immunopathology · doi:10.1007/s00281-014-0422-z