C/EBPβ is required for 'emergency' granulopoiesis

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Structural basis for effects of CpA modifications on C/EBPβ binding of DNA

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C/EBPβ promotes BCR–ABL-mediated myeloid expansion and leukemic stem cell exhaustion

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The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse

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Deletion of Tristetraprolin Caused Spontaneous Reactive Granulopoiesis by a Non–Cell-Autonomous Mechanism Without Disturbing Long-Term Hematopoietic Stem Cell Quiescence

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Long Non-coding RNAs: Regulators of the Activity of Myeloid-Derived Suppressor Cells

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Accelerated apoptosis of peripheral blood monocytes in Cebpb-deficient mice

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MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

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HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1

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Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation

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Lymphoid to Myeloid Cell Trans-Differentiation Is Determined by C/EBPβ Structure and Post-Translational Modifications

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In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis

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Hematopoietic stem cells undergo a lymphoid to myeloid switch in early stages of emergency granulopoiesis

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Myeloid-Derived Suppressor Cells Ameliorate Cyclosporine A–Induced Hypertension in Mice

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Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia

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The Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) Is Required for Termination of Emergency Granulopoiesis

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Orchestration of B lymphoid cells and their inner myeloid by Bach

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eQTLs identify regulatory networks and drivers of variation in the individual response to sepsis

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Systemic inoculation of Escherichia coli causes emergency myelopoiesis in zebrafish larval caudal hematopoietic tissue

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Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells

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Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ

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GM-CSF Programs Hematopoietic Stem and Progenitor Cells During Candida albicans Vaccination for Protection Against Reinfection

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Cebp1 and Cebpβ transcriptional axis controls eosinophilopoiesis in zebrafish

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The Transcription Factor C/EBP-β Mediates Constitutive and LPS-Inducible Transcription of Murine SerpinB2

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New insights on extramedullary granulopoiesis and neutrophil heterogeneity in the spleen and its importance in disease

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A CEBPB/IL-1β/TNF-α feedback loop drives drug resistance to venetoclax and MDM2 inhibitors in monocytic leukemia

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Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz

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Mathematical Analysis of Cytokine-Induced Differentiation of Granulocyte-Monocyte Progenitor Cells

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The acute myeloid leukemia microenvironment impairs neutrophil maturation and function through NF-κB signaling

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Bone Marrow AT 1 Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitors via Platelet-Derived SDF-1α

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Evolution and Targeting of Myeloid Suppressor Cells in Cancer: A Translational Perspective

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GM-CSF treatment is not effective in congenital neutropenia patients due to its inability to activate NAMPT signaling

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White Blood Cell and Neutrophil Counts and Response to Intravenous Immunoglobulin in Kawasaki Disease

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The gene signature in CCAAT-enhancer-binding protein dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors

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What fungal CNS infections can teach us about neuroimmunology and CNS-specific immunity

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Prevention of Bone Marrow Cell Apoptosis and Regulation of Hematopoiesis by Type I IFNs during Systemic Responses to Pneumocystis Lung Infection

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Chromatin Dynamics during Differentiation of Myeloid Cells

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Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality

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Macrophage-Derived IL-1β Regulates Emergency Myelopoiesis via the NF-κB and C/ebpβ in Zebrafish

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PU.1 is required to restrain myelopoiesis during chronic inflammatory stress

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EGR2 O-GlcNAcylation orchestrates the development of protumoral macrophages to limit CD8+ T cell antitumor responses

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Nitric Oxide: Regulation and Function in Neutrophil Immune Responses

Kumar, S., & Dikshit, M. (2024) · Antioxidants and Redox Signaling · doi:10.1089/ars.2022.0220 · Cited by 17

Identification of target genes of transcription factor CEBPB in acute promyelocytic leukemia cells induced by all-trans retinoic acid

Yu, L., Yang-de, Z., Zhou, J., Yao, D.-M., & Li, X. (2013) · Asian Pacific Journal of Tropical Medicine · doi:10.1016/s1995-7645(13)60077-2 · Cited by 14

Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis

Sánchez, Á., Relaño‐Rupérez, C., Carrasco, A., Contreras‐Jurado, C., Martín‐Duce, A., Aranda, A., & Alemany, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-04538-3 · Cited by 15

Human Isogenic Cell Line Models for Neutrophils and Myeloid-Derived Suppressor Cells

Zhang, Y., Wilt, E., & Lü, X. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207709 · Cited by 14

Mapping of MN1 Sequences Necessary for Myeloid Transformation

Kandilci, A., Surtel, J., Janke, L. J., Neale, G. A. M., Terranova, S., & Grosveld, G. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061706 · Cited by 14

Exploring the relationships between amphibian (Xenopus laevis) myeloid cell subsets

Yaparla, A., Koubourli, D. V., Popović, M., & Grayfer, L. (2020) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2020.103798 · Cited by 14

Granulocytic Phagocytes

Nauseef, W. M., & Clark, R. A. (2010) · Elsevier eBooks · doi:10.1016/b978-0-443-06839-3.00008-4 · Cited by 13

Innate lymphoid cells activated by the cytokine TL1A link colitis to emergency granulopoiesis and the recruitment of tumor-promoting neutrophils

Pires, S., Yang, W., Frigerio, S., Louis, C., Scott, C., Zhou, Y. L., Cardakli, E. D., Tran, N., Hassan‐Zahraee, M., Ye, Z., et al. (2026) · Immunity · doi:10.1016/j.immuni.2025.12.008 · Cited by 15

A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation

Radomska, H. S., Jernigan, F. E., Nakayama, S., Jorge, S. E., Sun, L., Tenen, D. G., & Kobayashi, S. S. (2015) · SLAS DISCOVERY · doi:10.1177/1087057115592220 · Cited by 15

Effects of Dopamine on stem cells and its potential roles in the treatment of inflammatory disorders: a narrative review

Liu, G., Liu, Z., Lin, Z., Chen, P., Yan, Y.-C., Lin, Q., Hu, Y., Jiang, N., & Yu, B. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03454-w · Cited by 15

The effect of inflammatory factors and their inhibitors on the hematopoietic stem cells fate

Najafi, S., Ghanavat, M., Shahrabi, S., Gatavizadeh, Z., & Saki, N. (2021) · Cell Biology International · doi:10.1002/cbin.11545 · Cited by 13

Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment

El‐Sharkawi, D., Sproul, D., Allen, C. G., Feber, A., Wright, M., Hills, R. K., Linch, D. C., & Gale, R. E. (2017) · Haematologica · doi:10.3324/haematol.2017.173096 · Cited by 13

In-silico analysis of myeloid cells across the animal kingdom reveals neutrophil evolution by colony-stimulating factors

Pinheiro, D., Mawhin, M., Prendecki, M. F., & Woollard, K. J. (2020) · eLife · doi:10.7554/elife.60214 · Cited by 12

Proteins That Read DNA Methylation

Liu, K., Shimbo, T., Song, X., Wade, P. A., & Min, J. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-11454-0_11 · Cited by 13

Foxp3+ regulatory T cells ensure B lymphopoiesis by inhibiting the granulopoietic activity of effector T cells in mouse bone marrow

Kim, S., Park, K., Choi, J., Jang, E., Paik, D., Seong, R. H., & Youn, J. (2014) · European Journal of Immunology · doi:10.1002/eji.201444532 · Cited by 12

C/EBPβ sustains the oncogenic program of AML cells by cooperating with MYB and co-activator p300 in a transcriptional module

Klempnauer, K. (2022) · Experimental Hematology · doi:10.1016/j.exphem.2022.01.003 · Cited by 12

C/EBPβ-induced lymphoid-to-myeloid transdifferentiation emulates granulocyte-monocyte progenitor biology

Nguyen, L. T., Zimmermann, K., Kowenz‐Leutz, E., Lim, R., Hofstätter, M., Mildner, A., & Leutz, A. (2023) · Stem Cell Reports · doi:10.1016/j.stemcr.2023.11.011 · Cited by 11

G-CSF-Induced Emergency Granulopoiesis Modulates Neutrophil Effector Function in Mice

Stephan, J., Knerr, T., Wells, C., Gu, Z., Johnson, S. R., Jobe, T. K., Isaacs, W. S., Hill, B. G., & Wysoczynski, M. (2025) · Stem Cell Reviews and Reports · doi:10.1007/s12015-025-10885-w · Cited by 12

HDAC11 regulates expression of C/EBPβ and immunosuppressive molecules in myeloid-derived suppressor cells

Chen, J., Cheng, F., Sahakian, E., Powers, J. J., Wang, Z., Tao, J., Seto, E., Pinilla-Ibarz, J. A., & Sotomayor, E. M. (2021) · Journal of Leukocyte Biology · doi:10.1002/jlb.1a1119-606rrr · Cited by 11

Granulocytic Phagocytes

DeLeo, F. R., & Nauseef, W. M. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-4801-3.00008-4 · Cited by 11

BCG-Induced Immune Training: Interplay between Trained Immunity and Emergency Granulopoiesis

Henok, A., Hollams, E. M., Kollmann, T. R., & Amenyogbe, N. (2023) · Journal of Molecular Biology · doi:10.1016/j.jmb.2023.168169 · Cited by 10

Mitochondrial perturbations in low-protein-diet-fed mice are associated with altered neutrophil development and effector functions

Thind, M. K., Miraglia, E., Ling, C., Khan, M. A., Glembocki, A. I., Bourdon, C., ChenMi, Y., Palaniyar, N., Glogauer, M., Bandsma, R., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114493 · Cited by 12

Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment

Kiss, M., Halász, L., Hadadi, É., Berger, W. K., Tzerpos, P., Póliska, S., Kancheva, D., Gabriel, A. A., Barthelmess, R. M., Debraekeleer, A., et al. (2025) · Genome Medicine · doi:10.1186/s13073-025-01511-y · Cited by 10

Recombinant Ganoderma lucidum Immunomodulatory Protein Improves the Treatment for Chemotherapy-Induced Neutropenia

Lei, X., Zhi, C., Huang, W., Sun, X., Gao, W., Yin, X., Zhang, X., Liang, C., Zhang, H., & Sun, F. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00956 · Cited by 11

Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish

Hall, C. J., Crosier, P. S., & Crosier, K. E. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.10.020 · Cited by 11

Heme oxygenase 1 affects granulopoiesis in mice through control of myelocyte proliferation

Bukowska-Straková, K., Cieśla, M., Szade, K., Nowak, W. N., Straka, R., Szade, A., Tyszka‐Czochara, M., Najder, K., Konturek-Cieśla, A., Siedlar, M., et al. (2016) · Immunobiology · doi:10.1016/j.imbio.2016.10.018 · Cited by 10

Role of Granulocyte Colony-stimulating Factor Therapy in Cirrhosis, ‘Inside Any Deep Asking Is the Answering’

Philips, C. A., Augustine, P., Ahamed, R., Rajesh, S. K., George, T., Valiathan, G. C., & John, S. K. (2019) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2019.00034 · Cited by 10

Candidemia-Induced Emergency Granulopoiesis Consists of Successive Dual Waves Triggered by the Shift From C/EBPalpha to C/EBPbeta Dependency.

Satake, S., Hirai, H., Shime, N., Nagao, R., Tanaka, R., Yao, H., Hayashi, Y., Ashihara, E., Inaba, T., Fujita, N., et al. (2010) · Blood · doi:10.1182/blood.v116.21.3778.3778

C/EBPβ-Mediated Expansion of Hematopoietic Stem/Progenitors Precedes ‘Emergency’ Granulopoiesis Induced by Candidemia.

Tamura, A., Hirai, H., Hayashi, Y., Yao, H., Yoshioka, S., Miura, Y., Ashihara, E., & Maekawa, T. (2012) · Blood · doi:10.1182/blood.v120.21.2336.2336

CREB Is Involved in the Regulation of C/EBPβ During 'emergency' Granulopoiesis.

Hirai, H., Kamio, N., Matsusue, A., Ogino, S., Kimura, N., Satake, S., Ashihara, E., Maekawa, T., Tenen, D. G., & Imanishi, J. (2009) · Blood · doi:10.1182/blood.v114.22.1457.1457

C/EBPβ Is Involved in the Amplification of Early Granulocyte Precursors during Candidemia-Induced “Emergency” Granulopoiesis

Satake, S., Hirai, H., Hayashi, Y., Shime, N., Tamura, A., Yao, H., Yoshioka, S., Miura, Y., Inaba, T., Fujita, N., et al. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103007 · Cited by 85

CCAAT/enhancer-binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony-stimulating factor receptor

Wang, Q., & Friedman, A. D. (2002) · Blood · doi:10.1182/blood.v99.8.2776 · Cited by 90