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Cited by 825

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells

Batten, Marcel, Li, Ji, Yi, Sothy, Kljavin, Noelyn M, Danilenko, Dimitry M, Lucas, Sophie, Lee, James, de Sauvage, Frederic J, Ghilardi, Nico·2006·Nature Immunology
DOI 10.1038/ni1375
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Research works printed but not linked: 35

  1. Pflanz, S. et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. Immunity 16, 779–790 (2002). · DOI · Paper page
  2. Hibbert, L., Pflanz, S., De Waal Malefyt, R. & Kastelein, R.A. IL-27 and IFN-α signal via STAT1 and STAT3 and induce T-bet and IL-12Rβ2 in naive T cells. J. Interferon Cytokine Res. 23, 513–522 (2003). · DOI · Paper page
  3. Lucas, S., Ghilardi, N., Li, J. & de Sauvage, F.J. IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through STAT1-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. USA 100, 15047–15052 (2003). · DOI · Paper page
  4. Takeda, A. et al. Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J. Immunol. 170, 4886–4890 (2003). · DOI · Paper page
  5. Chen, Q. et al. Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature 407, 916–920 (2000). · DOI · Paper page
  6. Pflanz, S. et al. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J. Immunol. 172, 2225–2231 (2004). · DOI · Paper page
  7. Sprecher, C.A. et al. Cloning and characterization of a novel class I cytokine receptor. Biochem. Biophys. Res. Commun. 246, 82–90 (1998). · DOI
  8. Holscher, C. et al. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J. Immunol. 174, 3534–3544 (2005). · DOI · Paper page
  9. Pearl, J.E. et al. IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice. J. Immunol. 173, 7490–7496 (2004). · DOI
  10. Villarino, A. et al. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 19, 645–655 (2003). · DOI · Paper page
  11. Yoshida, H. et al. WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection. Immunity 15, 569–578 (2001). · DOI · Paper page
  12. Artis, D. et al. The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. J. Immunol. 173, 5626–5634 (2004). · DOI · Paper page
  13. Hamano, S. et al. WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production. Immunity 19, 657–667 (2003). · DOI · Paper page
  14. Miyazaki, Y. et al. Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice. J. Immunol. 175, 2401–2407 (2005). · DOI
  15. Yamanaka, A. et al. Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A-induced hepatitis. J. Immunol. 172, 3590–3596 (2004). · DOI
  16. McKenzie, B.S., Kastelein, R.A. & Cua, D.J. Understanding the IL-23-IL-17 immune pathway. Trends Immunol. 27, 17–23 (2006). · DOI · Paper page
  17. Aggarwal, S., Ghilardi, N., Xie, M.H., de Sauvage, F.J. & Gurney, A.L. Interleukin 23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin 17. J. Biol. Chem. 278, 1910–1914 (2003). · DOI · Paper page
  18. Villarino, A.V. et al. IL-27 limits IL-2 production during Th1 differentiation. J. Immunol. 176, 237–247 (2006). · DOI · Paper page
  19. Owaki, T. et al. IL-27 suppresses CD28-mediated IL-2 production through suppressor of cytokine signaling 3. J. Immunol. 176, 2773–2780 (2006). · DOI
  20. Bettelli, E. et al. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J. Exp. Med. 200, 79–87 (2004). · DOI · Paper page
  21. Pasare, C. & Medzhitov, R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299, 1033–1036 (2003). · DOI · Paper page
  22. Kolls, J.K. & Linden, A. Interleukin-17 family members and inflammation. Immunity 21, 467–476 (2004). · DOI · Paper page
  23. Sergejeva, S., Ivanov, S., Lotvall, J. & Linden, A. Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation. Am. J. Respir. Cell Mol. Biol. 33, 248–253 (2005). · DOI · Paper page
  24. McQualter, J.L. et al. Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis. J. Exp. Med. 194, 873–882 (2001). · DOI · Paper page
  25. Samoilova, E.B., Horton, J.L., Hilliard, B., Liu, T.S. & Chen, Y. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J. Immunol. 161, 6480–6486 (1998). · DOI · Paper page
  26. Cho, M.L. et al. STAT3 and NF-κB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice. J. Immunol. 176, 5652–5661 (2006). · DOI · Paper page
  27. Chen, Z. et al. Selective regulatory function of SOCS3 in the formation of IL-17-secreting T cells. Proc. Natl. Acad. Sci. USA 103, 8137–8142 (2006). · DOI · Paper page
  28. Schimpl, A. et al. IL-2 and autoimmune disease. Cytokine Growth Factor Rev. 13, 369–378 (2002). · DOI
  29. Honda, K. et al. T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis. Inflamm. Bowel Dis. 11, 1044–1052 (2005). · DOI
  30. Jebbari, H., Roberts, C.W., Ferguson, D.J., Bluethmann, H. & Alexander, J. A protective role for IL-6 during early infection with Toxoplasma gondii. Parasite Immunol. 20, 231–239 (1998). · DOI
  31. Suzuki, Y. et al. Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice. Infect. Immun. 65, 2339–2345 (1997). · DOI
  32. Gao, W. & Pereira, M.A. Interleukin-6 is required for parasite specific response and host resistance to Trypanosoma cruzi. Int. J. Parasitol. 32, 167–170 (2002). · DOI
  33. Kelly, M.N. et al. Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect. Immun. 73, 617–621 (2005). · DOI · Paper page
  34. Doganci, A., Sauer, K., Karwot, R. & Finotto, S. Pathological role of IL-6 in the experimental allergic bronchial asthma in mice. Clin. Rev. Allergy Immunol. 28, 257–270 (2005). · DOI
  35. Sedgwick, J.D. et al. Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc. Natl. Acad. Sci. USA 88, 7438–7442 (1991). · DOI · Paper page

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Metadata

Authors
Batten, M., Li, J., Yi, S., Kljavin, N. M., Danilenko, D. M., Lucas, S., Lee, J., de Sauvage, F. J., & Ghilardi, N.
Venue
Nature Immunology
Publisher
Springer Science and Business Media LLC
Published
2006-08-13
Volume
7
Issue
9
Pages
929-936
ISSN
  • 1529-2908 (ISSN-L)
  • 1529-2916
DOI
10.1038/ni1375
OpenAlex
W2068577743
Cited by
825
References
9
FWCI
29.35
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)

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CoChat. (2026). Citation check: Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells. https://app.cochat.ai/papers/10.1038/ni1375
The paper
Batten, M., Li, J., Yi, S., Kljavin, N. M., Danilenko, D. M., Lucas, S., Lee, J., de Sauvage, F. J., & Ghilardi, N. (2006). Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells. Nature Immunology. https://doi.org/10.1038/ni1375

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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