Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

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Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips

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Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data.

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Purification and Cloning of Aggrecanase-1: A Member of the ADAMTS Family of Proteins

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Osteoarthritis development in novel experimental mouse models induced by knee joint instability

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Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS Family

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Syndecans: New Kids on the Signaling Block

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Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4

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Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS‐4 and ADAMTS‐5

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Syndecan-3 and Syndecan-4 Specifically Mark Skeletal Muscle Satellite Cells and Are Implicated in Satellite Cell Maintenance and Muscle Regeneration

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Syndecan-4 signals cooperatively with integrins in a Rhodependent manner in the assembly of focal adhesions and actin stress fibers

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Crucial role of macrophages in matrix metalloproteinase–mediated cartilage destruction during experimental osteoarthritis : Involvement of matrix metalloproteinase 3

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Characterization of and osteoarthritis susceptibility in ADAMTS‐4–knockout mice

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Gene deletion of either interleukin‐1β, interleukin‐1β–converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy

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ADAMTS4 (Aggrecanase-1) Activation on the Cell Surface Involves C-terminal Cleavage by Glycosylphosphatidyl Inositol-anchored Membrane Type 4-Matrix Metalloproteinase and Binding of the Activated Proteinase to Chondroitin Sulfate and Heparan Sulfate on Syndecan-1

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The regulation of the ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review.

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Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4)

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Syndecan-4 Modulates Focal Adhesion Kinase Phosphorylation

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Proprotein Convertase Furin Interacts with and Cleaves Pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi Network

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Direct Binding of Syndecan-4 Cytoplasmic Domain to the Catalytic Domain of Protein Kinase Cα (PKCα) Increases Focal Adhesion Localization of PKCα

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Validity of histopathological grading of articular cartilage from osteoarthritic knee joints

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Development of Osteoarthritis in the Knee Joints of Wistar Rats After Strenuous Running Exercise in a Running Wheel by Intracranial Self-Stimulation

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Characterization of proADAMTS5 processing by proprotein convertases

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Proteolysis of the collagen fibril in osteoarthritis

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Differential expression of fibroblast growth factor receptor-1, -2, and -3 and syndecan-1, -2, and -4 in neonatal rat mandibular condyle and calvaria during osteogenic differentiation in vitro

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ADAMTS-4 (aggrecanase-1): N-Terminal activation mechanisms

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Collagen and Aggrecan Degradation Is Blocked in Interleukin-1-Treated Cartilage Explants by an Inhibitor of IκB Kinase through Suppression of Metalloproteinase Expression

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Semiquantitative reverse transcription-polymerase chain reaction analysis of syndecan-1 and -4 messages in cartilage and cultured chondrocytes from osteoarthritic joints

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Remodelling the extracellular matrix in development and disease

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Heparan Sulfate Proteoglycans

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Inflammation in osteoarthritis

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